Archive for the ‘Metabolomics’ Category

Reporter and Curator: Dr. Sudipta Saha, Ph.D.


Food is digested by bathing in enzymes that break down its molecules. Those molecular fragments then pass through the gut wall and are absorbed in our intestines. But our bodies make a limited range of enzymes, so that we cannot break down many of the tough compounds in plants. The term “dietary fiber” refers to those indigestible molecules. These dietary fibers are indigestible only to us. The gut is coated with a layer of mucus, on which sits a carpet of hundreds of species of bacteria, part of the human microbiome. Some of these microbes carry the enzymes needed to break down various kinds of dietary fibers.


Scientists at the University of Gothenburg in Sweden are running experiments that are yielding some important new clues about fiber’s role in human health. Their research indicates that fiber doesn’t deliver many of its benefits directly to our bodies. Instead, the fiber we eat feeds billions of bacteria in our guts. Keeping them happy means our intestines and immune systems remain in good working order. The scientists have recently reported that the microbes are involved in the benefits obtained from the fruits-and-vegetables diet. Research proved that low fiber diet decreases the gut bacteria population by tenfold.


Along with changes to the microbiome there were also rapid changes observed in the experimental mice. Their intestines got smaller, and its mucus layer thinner. As a result, bacteria wound up much closer to the intestinal wall, and that encroachment triggered an immune reaction. After a few days on the low-fiber diet, mouse intestines developed chronic inflammation. After a few weeks, they started putting on fat and developing higher blood sugar levels. Inflammation can help fight infections, but if it becomes chronic, it can harm our bodies. Among other things, chronic inflammation may interfere with how the body uses the calories in food, storing more of it as fat rather than burning it for energy.


In a way fiber benefits human health is by giving, indirectly, another source of food. When bacteria finished harvesting the energy in the dietary fiber, they cast off the fragments as waste. That waste — in the form of short-chain fatty acids — is absorbed by intestinal cells, which use it as fuel. But the gut’s microbes do more than just make energy. They also send messages. Intestinal cells rely on chemical signals from the bacteria to work properly. The cells respond to the signals by multiplying and making a healthy supply of mucus. They also release bacteria-killing molecules. By generating these responses, gut bacteria help to maintain a peaceful coexistence with the immune system. They rest on the gut’s mucus layer at a safe distance from the intestinal wall. Any bacteria that wind up too close get wiped out by antimicrobial poisons.


A diet of fiber-rich foods, such as fruits and vegetables, reduces the risk of developing diabetes, heart disease and arthritis. Eating more fiber seems to lower people’s mortality rate, whatever be the cause. Researchers hope that they will learn more about how fiber influences the microbiome to use it as a way to treat disorders. Lowering inflammation with fiber may also help in the treatment of immune disorders such as inflammatory bowel disease. Fiber may also help reverse obesity. They found that fiber supplements helped obese people to lose weight. It’s possible that each type of fiber feeds a particular set of bacteria, which send their own important signals to our bodies.





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  1. Lungs can supply blood stem cells and also produce platelets: Lungs, known primarily for breathing, play a previously unrecognized role in blood production, with more than half of the platelets in a mouse’s circulation produced there. Furthermore, a previously unknown pool of blood stem cells has been identified that is capable of restoring blood production when bone marrow stem cells are depleted.


  1. A new drug for multiple sclerosis: A new multiple sclerosis (MS) drug, which grew out of the work of UCSF (University of California, San Francisco) neurologist was approved by the FDA. Ocrelizumab, the first drug to reflect current scientific understanding of MS, was approved to treat both relapsing-remitting MS and primary progressive MS.


  1. Marijuana legalized – research needed on therapeutic possibilities and negative effects: Recreational marijuana will be legal in California starting in January, and that has brought a renewed urgency to seek out more information on the drug’s health effects, both positive and negative. UCSF scientists recognize marijuana’s contradictory status: the drug has proven therapeutic uses, but it can also lead to tremendous public health problems.


  1. Source of autism discovered: In a finding that could help unlock the fundamental mysteries about how events early in brain development lead to autism, researchers traced how distinct sets of genetic defects in a single neuronal protein can lead to either epilepsy in infancy or to autism spectrum disorders in predictable ways.


  1. Protein found in diet responsible for inflammation in brain: Ketogenic diets, characterized by extreme low-carbohydrate, high-fat regimens are known to benefit people with epilepsy and other neurological illnesses by lowering inflammation in the brain. UCSF researchers discovered the previously undiscovered mechanism by which a low-carbohydrate diet reduces inflammation in the brain. Importantly, the team identified a pivotal protein that links the diet to inflammatory genes, which, if blocked, could mirror the anti-inflammatory effects of ketogenic diets.


  1. Learning and memory failure due to brain injury is now restorable by drug: In a finding that holds promise for treating people with traumatic brain injury, an experimental drug, ISRIB (integrated stress response inhibitor), completely reversed severe learning and memory impairments caused by traumatic brain injury in mice. The groundbreaking finding revealed that the drug fully restored the ability to learn and remember in the brain-injured mice even when the animals were initially treated as long as a month after injury.


  1. Regulatory T cells induce stem cells for promoting hair growth: In a finding that could impact baldness, researchers found that regulatory T cells, a type of immune cell generally associated with controlling inflammation, directly trigger stem cells in the skin to promote healthy hair growth. An experiment with mice revealed that without these immune cells as partners, stem cells cannot regenerate hair follicles, leading to baldness.


  1. More intake of good fat is also bad: Liberal consumption of good fat (monounsaturated fat) – found in olive oil and avocados – may lead to fatty liver disease, a risk factor for metabolic disorders like type 2 diabetes and hypertension. Eating the fat in combination with high starch content was found to cause the most severe fatty liver disease in mice.


  1. Chemical toxicity in almost every daily use products: Unregulated chemicals are increasingly prevalent in products people use every day, and that rise matches a concurrent rise in health conditions like cancers and childhood diseases, Thus, researcher in UCSF is working to understand the environment’s role – including exposure to chemicals – in health conditions.


  1. Cytomegalovirus found as common factor for diabetes and heart disease in young women: Cytomegalovirus is associated with risk factors for type 2 diabetes and heart disease in women younger than 50. Women of normal weight who were infected with the typically asymptomatic cytomegalovirus, or CMV, were more likely to have metabolic syndrome. Surprisingly, the reverse was found in those with extreme obesity.




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Reporter and Curator: Dr. Sudipta Saha, Ph.D.


The trillions of microbes in the human gut are known to aid the body in synthesizing key vitamins and other nutrients. But this new study suggests that things can sometimes be more adversarial.


Choline is a key nutrient in a range of metabolic processes, as well as the production of cell membranes. Researchers identified a strain of choline-metabolizing E. coli that, when transplanted into the guts of germ-free mice, consumed enough of the nutrient to create a choline deficiency in them, even when the animals consumed a choline-rich diet.


This new study indicate that choline-utilizing bacteria compete with the host for this nutrient, significantly impacting plasma and hepatic levels of methyl-donor metabolites and recapitulating biochemical signatures of choline deficiency. Mice harboring high levels of choline-consuming bacteria showed increased susceptibility to metabolic disease in the context of a high-fat diet.


DNA methylation is essential for normal development and has been linked to everything from aging to carcinogenesis. This study showed changes in DNA methylation across multiple tissues, not just in adult mice with a choline-consuming gut microbiota, but also in the pups of those animals while they developed in utero.


Bacterially induced reduction of methyl-donor availability influenced global DNA methylation patterns in both adult mice and their offspring and engendered behavioral alterations. This study reveal an underappreciated effect of bacterial choline metabolism on host metabolism, epigenetics, and behavior.


The choline-deficient mice with choline-consuming gut microbes also showed much higher rates of infanticide, and exhibited signs of anxiety, with some mice over-grooming themselves and their cage-mates, sometimes to the point of baldness.


Tests have also shown as many as 65 percent of healthy individuals carry genes that encode for the enzyme that metabolizes choline in their gut microbiomes. This work suggests that interpersonal differences in microbial metabolism should be considered when determining optimal nutrient intake requirements.




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The Biologic Roles of Leptin in Metabolism, Leptin Physiology and Obesity: On the Mechanism of Action of the Hormone in Energy Balance

Reporter: Aviva Lev-Ari, PhD, RN


More than $140 billion is spent each year in the United States to treat obesity-related diseases, according to the CDC.

Worldwide obesity rates have doubled since 1980, and most people now live in countries where more deaths are caused by overweight and obesity than by malnourishment, according to the World Health Organization.

Treatment with leptin was approved in the United States in 2014 for use in congenital leptin deficiency as well as in an unusual syndrome of lipodystrophy, but the protein has not been readily available for clinical experiments.

These are the conclusions in a commentary published June 22 in Cell Metabolism by Harvard Medical School metabolism experts Jeffrey Flier and Eleftheria Maratos-Flier.

Flier, the HMS George Higginson Professor of Physiology and Medicine, and Maratos-Flier, HMS professor of medicine at Beth Israel Deaconess Medical Center, have made significant contributions to the understanding of the metabolism of obesity and starvation in general, and of leptin in particular.

The role for leptin as a starvation signal is now well established. [T]he physiologic role of leptin in most individuals may be limited to signaling the response to hunger or starvation, and then reversing that signal as energy stores are restored


“We continue to believe that healthy and lean individuals exist who resist obesity at least in part through their leptin levels, and that some individuals develop obesity because they have insufficiently elevated leptin levels or cellular resistance to leptin,” Flier said.

“But in science, belief and knowledge are two different things, and as much as we may lean toward this belief, we ought to develop evidence for this hypothesis or abandon it in favor of new potential mechanisms for the regulation of body weight,” he said.


Leptin’s Physiologic Role: Does the Emperor of Energy Balance Have No Clothes?

Jeffrey S. Flier'Correspondence information about the author Jeffrey S. Flier


Eleftheria Maratos-Flier
Publication stage: In Press Corrected Proof

Seeking evidence for anti-obesity claim – Does the Emperor Have Clothes?

Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity

Maren Leifheit-Nestler12, Nana-Maria Wagner13, Rajinikanth Gogiraju1,Michael Didié14, Stavros Konstantinides15, Gerd Hasenfuss1and Katrin Schäfer1*

J Translational Medicine: Cardiovascular, Metabolic and Lipoprotein Translation. 2013; 11:170.


Other related articles on LEPTIN published in this Open Access Online Scientific Journal include the following:


Leptin signaling in mediating the cardiac hypertrophy associated with obesity

Larry H Bernstein, MD, FCAP, Reviewer, and Aviva Lev-Ari, PhD, RN


Leptin and Puberty

Reporter and Curator: Dr. Sudipta Saha, Ph.D.


Pregnancy with a Leptin-Receptor Mutation

Reporter and Curator: Dr. Sudipta Saha, Ph.D.


New Insights into mtDNA, mitochondrial proteins, aging, and metabolic control

Curator: Larry H. Bernstein, MD, FCAP

Adipocyte Derived Stroma Cells: Their Usage in Regenerative Medicine and Reprogramming into Pancreatic Beta-Like Cells

Curator: Evelina Cohn, PhD

Fat Cells Reprogrammed to Make Insulin

Curator: Larry H. Bernstein, MD, FCAP

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Functional Analysis of the Microbiome for Development of Potential Therapeutic Approaches to Weight Regain

Reporter: Aviva Lev-Ari, PhD, RN


Transplanting fecal microbes to prevent recurring obesity

Finally, the researchers used these insights to develop new treatments for recurrent obesity. They implanted formerly obese mice with gut microbes from mice that had never been obese. This fecal microbiome transplantation erased the “memory” of obesity in these mice when they were re-exposed to a high-calorie diet, preventing excessive recurrent obesity.

Gut Microbes Contribute to Recurrent ‘Yo-Yo’ Obesity, Study Shows

By Einat Paz-Frankel, NoCamels December 18, 2016

Researchers at Israel’s Weizmann Institute of Science have shown in mice that intestinal microbes – collectively termed the gut microbiome – play an unexpectedly important role in exacerbated post-dieting weight gain, and that this common phenomenon may in the future be prevented or treated by altering the composition or function of the microbiome.

“We’ve shown in obese mice that following successful dieting and weight loss, the microbiome retains a ‘memory’ of previous obesity,” Elinav said in a statement. “This persistent microbiome accelerated the regaining of weight when the mice were put back on a high-calorie diet or ate regular food in excessive amounts.”


Original Research

Persistent microbiome alterations modulate the rate of post-dieting weight regain

Nature (2016) doi:10.1038/nature20796

Corrected online

28 November 2016

Article tools


In tackling the obesity pandemic, significant efforts are devoted to the development of effective weight reduction strategies, yet many dieting individuals fail to maintain a long-term weight reduction, and instead undergo excessive weight regain cycles. The mechanisms driving recurrent post-dieting obesity remain largely elusive. Here, we identify an intestinal microbiome signature that persists after successful dieting of obese mice, which contributes to faster weight regain and metabolic aberrations upon re-exposure to obesity-promoting conditions and transmits the accelerated weight regain phenotype upon inter-animal transfer. We develop a machine-learning algorithm that enables personalized microbiome-based prediction of the extent of post-dieting weight regain. Additionally, we find that the microbiome contributes to diminished post-dieting flavonoid levels and reduced energy expenditure, and demonstrate that flavonoid-based ‘post-biotic’ intervention ameliorates excessive secondary weight gain. Together, our data highlight a possible microbiome contribution to accelerated post-dieting weight regain, and suggest that microbiome-targeting approaches may help to diagnose and treat this common disorder.

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Metabolic Genomics & Pharmaceutics



Author, Curator and Editor

Larry H Bernstein, MD, FCAP

Chief Scientific Officer

Leaders in Pharmaceutical Business Intelligence

Chapter 1: Metabolic Pathways

1.1            Carbohydrate Metabolism

1.2            Studies of Respiration Lead to Acetyl CoA

1.3            Pentose Shunt, Electron Transfer, Galactose, more Lipids in brief

1.4            The Multi-step Transfer of Phosphate Bond and Hydrogen Exchange Energy

1.5            Diabetes Mellitus

1.6            Glycosaminoglycans, Mucopolysaccharides, L-iduronidase, Enzyme Therapy

Chapter 2: Lipid Metabolism

2.1            Lipid Classification System

2.2            Essential Fatty Acids

2.3            Lipid Oxidation and Synthesis of Fatty Acids

2.4            Cholesterol and Regulation of Liver Synthetic Pathways

2.5            Sex hormones, Adrenal cortisol, Prostaglandins

2.6            Cytoskeleton and Cell Membrane Physiology

2.7            Pharmacological Action of Steroid hormone

Chapter 3: Cell Signaling

3.1            Signaling and Signaling Pathways

3.2            Signaling Transduction Tutorial

3.3            Selected References to Signaling and Metabolic Pathways in Leaders in Pharmaceutical Intelligence

3.4            Integrins, Cadherins, Signaling and the Cytoskeleton

3.5            Complex Models of Signaling: Therapeutic Implications

3.6            Functional Correlates of Signaling Pathways

Chapter 4: Protein Synthesis and Degradation

4.1            The Role and Importance of Transcription Factors

4.2            RNA and the Transcription of the Genetic Code

4.3            9:30 – 10:00, 6/13/2014, David Bartel “MicroRNAs, Poly(A) tails and Post-transcriptional Gene Regulation

4.4            Transcriptional Silencing and Longevity Protein Sir2

4.5            Ca2+ Signaling: Transcriptional Control

4.6            Long Noncoding RNA Network regulates PTEN Transcription

4.7            Zinc-Finger Nucleases (ZFNs) and Transcription Activator–Like Effector Nucleases (TALENs)

4.8            Cardiac Ca2+ Signaling: Transcriptional Control

4.9            Transcription Factor Lyl-1 Critical in Producing Early T-Cell Progenitors

4.10            Human Frontal Lobe Brain: Specific Transcriptional Networks

4.11            Somatic, Germ-cell, and Whole Sequence DNA in Cell Lineage and Disease

Chapter 5:  Sub-cellular Structure

5.1            Mitochondria: Origin from Oxygen free environment, Role in Aerobic Glycolysis and Metabolic Adaptation

5.2            Mitochondrial Metabolism and Cardiac Function

5.3            Mitochondria: More than just the “Powerhouse of the Cell”

5.4            Mitochondrial Fission and Fusion: Potential Therapeutic Targets?

5.5            Mitochondrial Mutation Analysis might be “1-step” Away

5.6            Autophagy-Modulating Proteins and Small Molecules Candidate Targets for Cancer Therapy: Commentary of Bioinformatics Approaches

5.7            Chromatophagy, A New Cancer Therapy: Starve The Diseased Cell Until It Eats Its Own DNA

5.8           A Curated Census of Autophagy-Modulating Proteins and Small Molecules Candidate Targets for Cancer Therapy

5.9           Role of Calcium, the Actin Skeleton, and Lipid Structures in Signaling and Cell Motility

Chapter 6: Proteomics

6.1            Proteomics, Metabolomics, Signaling Pathways, and Cell Regulation: a Compilation of Articles in the Journal

6.2            A Brief Curation of Proteomics, Metabolomics, and Metabolism

6.3            Using RNA-seq and Targeted Nucleases to Identify Mechanisms of Drug Resistance in Acute Myeloid Leukemia, SK Rathe in Nature, 2014

6.4            Proteomics – The Pathway to Understanding and Decision-making in Medicine

6.5            Advances in Separations Technology for the “OMICs” and Clarification of Therapeutic Targets

6.6           Expanding the Genetic Alphabet and Linking the Genome to the Metabolome

6.7            Genomics, Proteomics and Standards

6.8            Proteins and Cellular Adaptation to Stress

6.9            Genes, Proteomes, and their Interaction

6.10           Regulation of Somatic Stem Cell Function

6.11           Scientists discover that Pluripotency factor NANOG is also active in Adult Organism

Chapter 7: Metabolomics

7.1            Extracellular Evaluation of Intracellular Flux in Yeast Cells

7.2            Metabolomic Analysis of Two Leukemia Cell Lines Part I

7.3            Metabolomic Analysis of Two Leukemia Cell Lines Part II

7.4            Buffering of Genetic Modules involved in Tricarboxylic Acid Cycle Metabolism provides Homeomeostatic Regulation

7.5            Metabolomics, Metabonomics and Functional Nutrition: The Next Step in Nutritional Metabolism and Biotherapeutics

7.6            Isoenzymes in Cell Metabolic Pathways

7.7            A Brief Curation of Proteomics, Metabolomics, and Metabolism

7.8            Metabolomics is about Metabolic Systems Integration

7.9             Mechanisms of Drug Resistance

7.10           Development Of Super-Resolved Fluorescence Microscopy

7.11            Metabolic Reactions Need Just Enough

Chapter 8.  Impairments in Pathological States: Endocrine Disorders; Stress Hypermetabolism and CAncer

8.1           Omega3 Fatty Acids, Depleting the Source, and Protein Insufficiency in Renal Disease

8.2             Liver Endoplasmic Reticulum Stress and Hepatosteatosis

8.3            How Methionine Imbalance with Sulfur Insufficiency Leads to Hyperhomocysteinemia

8.4            AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth InVivo

8.5           A Second Look at the Transthyretin Nutrition Inflammatory Conundrum

8.6            Mitochondrial Damage and Repair under Oxidative Stress

8.7            Metformin, Thyroid Pituitary Axis, Diabetes Mellitus, and Metabolism

8.8            Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?

8.9            Social Behavior Traits Embedded in Gene Expression

8.10          A Future for Plasma Metabolomics in Cardiovascular Disease Assessment

Chapter 9: Genomic Expression in Health and Disease 

9.1            Genetics of Conduction Disease: Atrioventricular (AV) Conduction Disease (block): Gene Mutations – Transcription, Excitability, and Energy Homeostasis

9.2            BRCA1 a Tumour Suppressor in Breast and Ovarian Cancer – Functions in Transcription, Ubiquitination and DNA Repair

9.3            Metabolic Drivers in Aggressive Brain Tumors

9.4            Modified Yeast Produces a Range of Opiates for the First time

9.5            Parasitic Plant Strangleweed Injects Host With Over 9,000 RNA Transcripts

9.6            Plant-based Nutrition, Neutraceuticals and Alternative Medicine: Article Compilation the Journal

9.7            Reference Genes in the Human Gut Microbiome: The BGI Catalogue

9.8            Two Mutations, in the PCSK9 Gene: Eliminates a Protein involved in Controlling LDL Cholesterol

9.9            HDL-C: Target of Therapy – Steven E. Nissen, MD, MACC, Cleveland Clinic vs Peter Libby, MD, BWH



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7th International Conference and Exhibition on Metabolomics, November 14-16, 2016, Orlando, Florida

Reporter: Aviva Lev-Ari, PhD, RN



Conference Series LLC welcomes you to attend the 7th International Conference and Exhibition on Metabolomics during November 14-16, 2016 ,Florida, USA.This is an excellent opportunity for the delegates from Universities and Institutes to interact with the world class Scientists. The main theme of the conference is “Ground Breaking Analytical Concepts and Computational Methods”.

Metabolomics 2016  Conference will be an exploration of New research Innovation of Metabolomics and cover the latest developments and trends in Metabolomics modeling, Proteomics, Systems Biology, Genomics, Precision Medicine, Lipidomics, LC-MS and GC-MS Techniques, Bioinformatics, Plant Metabolomics, Clinical metabolomics, cancer and metabolism, computational biology, metabolomics syndrome, Nutritional Metabolomics, Therapeutic Metabolomics and more. Metabolomics is of interest to physicians because it may lead to improvements in the diagnosis and treatments of human diseases.

Theme: Ground Breaking Analytical Concepts and Computational Methods

Track 1 : Cancer Therapeutic Approaches 

Cancer is devastating illness that changes the digestion system of a cell and therefore the encompassing environment. Metabolomics in pharmaceutical examination turning into associate degree inexorably thought instrument within the life sciences since it’s a typically fast and precise procedure that may be connected with either a particular center or in a very worldwide manner to uncover new learning regarding organic frameworks. NFCR has sent quite $330 million in subsidizing to growth analysis prompting numerous leaps forward, together with offsetting action methodologies, previous analytic systems, and new antineoplastic medications and coverings. The Division of Cancer Biology (DCB) bolsters and encourages basic examination in each facet of neoplasm science at scholarly establishments and exploration establishments over the US and abroad. As a significant facet of the National Cancer Institute, the Federal Government’s foremost workplace for growth analysis and making ready, DCB provides finance for the analytical research that examines the elemental science behind all events of Cancer. Current Metabolomic approaches is being used to search out symptomatic Cancer biomarkers within the clinic, to search out pathways enclosed in illness that might be used for brand spanking new targets and to screen metabolic biomarkers amid remedial mediation. Concentrating on growth through metabolomics, might uncover metabolite stage for hearty approval of biomarkers for Cancer that might be useful for its future forecast, conclusion and treatment. There are various novel ways to handle cancer medicine that have utilized a scope of assorted informative stages. At that point once Cancer digestion system meets frameworks science system models would possibly manual for growth treatment.

Relevant Conferences: Fifth World Congress on Cancer medical aid, September 28-30, 2015 Atlanta, USA; Cancer medicine Conference & Exhibition, June 13-15, 2016, Rome, Italy; International Conference on Cancer immunology and its therapy Conference July 28-30, 2016 Melbourne, Australia; Ninth  Indo Global Summit on Cancer Therapy, November 02-04, 2015, Hyderabad, India; Second International Conference on Breast Cancer , September 19-21, 2016 Phoenix, USA; Novel Cancer therapeutics Summit, November 16-17, 2016 San Francisco city, USA; European lung cancer Conference, April 13-16, 2016, Geneva, Switzerland; Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, March 6–10, 2016, Whistler, Canada; IMPAKT Breast Cancer Conference, may 12 – 14, 2016, Brussels, Belgium.

Track 2 : Metabolomics Applications in Diseases

Metabolomics is connected to analyze a few human ill health issues, to boost their determination and aversion, and to stipulate higher essential systems. Metabolomic identification has been utilized to differentiate novel biomarkers and mechanisms of Cardiovascular Disease risk. Nourishment and Metabolism Center and Center for Human Genetics at Duke University where the examination goes ahead with National Institutes of Health awards. Metabolomics could offer constrained preferences in relevancy alternative “omics” advancements (genomics, proteomics, and Transcriptomics) in diabetes research. CEDAM (Center for Endocrinology, Diabetes and Metabolism) exploration is concentrated on a seat to-bedside approach, taking examination through from basic science speech act to clinical application. this is often inspired by ebb and flow MRC Experimental medication and Biomarker Grants and improved by the close neighborhood of research laboratory offices, Welcome Trust Clinical center and also the Queen Elizabeth Hospital (University Hospital NHS Foundation Trust). Metabolomic approach offers novel experiences into the mechanistic studies of antitumor medications from an extent specific from Traditional Medicine drugs investigations. Totally different and new advancements have been made for technique improvement of metabolomics. Specialized advances have prodded the utilization of metabolomics in AN assortment of varied examination zones spreading over essential, biomedical, and clinical sciences.

Relevant Conferences : Sixth International Metabolomics Conference, being conducted from Nov 28-30, 2016 Chicago, USA; Fifth World Congress on Neurology and therapeutics, March 14-16, 2016, Rome, Italy; International Conference on Cardiovascular Nursing, May 5-7, 2016, Chicago, USA; 11th International Conference on Targeting diabetes and Novel therapeutics, October 17-19, 2016 Kuala Lumpur, Malaysia; Epigenetic and Metabolic Regulation of Aging and Aging-Related Diseases, May 1-5, 2016, Santa Fe, USA; seventeenth International Meeting: Cell & Molecular biology Of genus Chlamydomonas, June 26 –July 1 2016, Kyoto, Japan; 18th International Conference on Genetic science and Molecular biology, October 10 -11 2016, Osaka, Japan; 13th International Congress of Human Genetic science,  April 3-7 2016, Kyoto, Japan.

Track 3 : Metabolomics in Precision Medicine

Metabolomics, the post-genomic investigation of the particles and procedures that conjure digestion system, shows up as a possible radical higher approach for observing science and ill health. Precision medication could be a path to agitate finding and making medications and antibodies that conveys unmatched results for patients, by incorporating clinical and sub-atomic information to understand the organic premise of infection. Pharmacometabolomics informs and compliments pharmacogenomics and along with, they offer building items to Quantitative and Systems pharmacological medicine. Preciseness offers next generation solutions to maximize your success in translational analysis. The arrival of huge parallel sequencing is accountable of a paradigm shift in biomarker discovery and clinical test style on the approach to what’s currently referred to as “biomarker-driven cancer medicine” or “precision medicine.”  Complementing hearty ventures to comprehensively bolster exploration, improvement, and advancement, the President’s 2016 Budget can provide a $215 million speculation to the National Institutes of Health (NIH), along with the Food and Drug Administration (FDA), and therefore the office of the National organizer for Health Information Technology (ONC) to backing this effort.

Relevant Conferences: International Conference on precision Medicine or  drugs, November 03-05, 2016, Baltimore, USA; Fifth International Conference on Translational Medicine, November 17-19 2016, San Francisco , USA; Fourth International Conference on prognostic, Preventive and Personalized Medicine & Molecular Diagnostics Sep 19-21 2016, Phoenix, USA; Second International Conference and Exhibition on Molecular Medicine or drugs and medical specialty, Sep 26-28, 2016 Miami, USA; International Conference on Medicinal Chemistry & Computer Aided Drug Designing December 01-03, 2016 Chicago, USA; International Conference on General Medicine & Dental Practice, November 7-9, 2016 Istanbul, Turkey; Precision Medicine, March 7–9 2016,San Francisco, CA; The Personalized Medicine World Conference (PMWC) 2016, San Francisco city, USA; Eighteenth International Conference on Genetics science and Molecular biology science, October 10-11, 2016 Osaka, Japan; thirteenth International Congress of Human Genetic science, April 3-7 2016, Kyoto, Japan.

Track 4 : Frontiers of Metabolomics Research

Metabolomic studies will prompt improved comprehension of ill health instruments and to new diagnostic markers and in addition upgraded comprehension of drug for medication or xenobiotic impact and hyperbolic ability to predict individual variation in drug response phenotypes. Howard University Center for computational Biology and Bioinformatics (CCBB) is to energize and advance the use of computational approach that deals with the investigation of both medical, biological and infection forms. New software system and progressively refined NMR metabolite spectral databases are dynamical the fascinating capacities of NMR chemical analysis to acknowledge and measure very little particles in declare investigations of substance metabolite biomarkers and metabolic flux. NIH Awards $1.6M to Fund micro RNA Biomarker analysis in Cancer, Alzheimer’s disease. The Bill and Melinda Gates Foundation these days reported $7.7 million in subsidizing for ten new permits to tell apart biomarkers for diagnosing Tuberculosis (TB) in low-asset settings. NMR metabolomics to demonstrate that divergent environmental signals area unit transduced into common Metabolomic changes that are “sensed” by metabolite responsive regulators.

Relevant Conferences: Seventh International Conference on Biomarkers & Clinical Research analysis, November 28-30, 2016, Baltimore, USA; Sixth International Conference & Expo exhibition on proteomics March 29-30, 2016, Atlanta, USA; Fifth  International Conference on Medicinal Chemistry Computer aided  Drug Designing December 01-03, 2016 Chicago, USA; Second International Conference and Exhibition on Molecular Medicine  and Diagnostics Sept 26-28, 2016 Miami, USA; Precision Medicine, March 7 – 9 2016,San Francisco, CA; The personalized medicine World Conference (PMWC) 2016, San Francisco, USA; Seventeenth International Meeting: Cell & Molecular biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan; 18th International Conference on Genetic science and Molecular biology, Oct 10 – 11 2016, Osaka, Japan; 13th International Congress of Human Genetic science, April 3-7 2016, Kyoto, Japan.

Track 5 : Therapeutic Metabolomics

Metabolomics is one amongst the relative newcomers of the omics methods and is probably be one of the most firmly known with real infection pathophysiology. The role of metabolism in immunity has been underexplored during this approach; on the other hand scientists have created crucial commitments in depicting relationship of unsusceptible procedures and metabolic pathways. Systems immunology aims to review the immunological system within a lot of integrated perspective on how entities and players participate at completely different system levels to the immune function. Computational immunology could be a field of science that encompasses high-throughput genomic and bioinformatics approaches to immunology. The combination of genomic information and reenactment of the motion of the resistant framework, in one single device, offers new points of study for a superior comprehension of the safe framework. The Honorable Michelle Rempel, pastor of state for western monetary enlargement, these days reported a venture of about $3 million toward leading edge metabolomics analysis gear for the U of A’s another Metabolomics Technology Demonstration Center, viz., set to open within the spring of 2015.

Relevant ConferencesInternational Conference on Clinical and Molecular Genetics, Nov 28-30, 2016, Chicago, USA; International Conference on Cancer Immunology and Immunotherapy Conference July 28-30, 2016 Melbourne, Australia; Fifth International Conference on Translational Medication, Nov 17-19 2016, San Francisco , USA; Second International Conference and Exhibition on Molecular Medicine and Diagnostics September 26-28, 2016 Miami, USA; Epigenetic and Metabolic Regulation of Aging and Aging-Related Diseases, May 1-5, 2016,Santa Fe, USA; Seventeenth International Meeting: Cell & Molecular Biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan; 18th International Conference on Genetics and Molecular Biology, Oct 10 – 11 2016, Osaka, Japan; 13th International Congress of Human Genetics, April 3-7 2016, Kyoto, Japan.

Track 6 : Transcriptomics & Metabolic pathways

Transcriptomics is the study of the transcriptome, the entire set of RNA transcripts that are delivered by the genome, under explicit circumstances or in an exceedingly explicit cell utilizing high-throughput routines, example, and microarray analysis. The worldwide Transcriptomics business sector is relied upon to develop at a CAGR of 13.7% amid the figure time of 2014 to 2019 and is evaluated to be value $3,773.0 million by 2019. The Transcriptomics market has manifestly developed within the previous few years basically due to the expanding mechanical headways within the field of sequencing advances in Transcriptomics analysis. Recent advances in Metabolomic measurement technologies are dramatic, extracting biological insight from complicated metabolite profiles remains a challenge, an analytical strategy that uses information obtained from high resolution LC–mass spectrum analysis and a bioinformatics toolset for detecting actively dynamic  metabolic pathways upon external perturbation. RNA-Seq recently developed approach with transcriptome profiling that uses profound sequencing advancements. The National Human genome analysis Institute (NHGRI), that could be a piece of the National Institutes of Health (NIH), has partaken in 2 ventures that created transcriptome assets for scientists round the globe the mammalian gene collection activity and the Mouse Transcriptome Project.

Relevant Conferences: 5th International Conference on Translational Medicine, November 17-19, 2016 San Francisco, USA; 2nd International Conference on Transcriptomics, August 18-20, 2016 Portland, Oregon USA; Fifth International Conference on Computational Systems Biology , August 22-23, 2016 Philadelphia USA ; International Conference on Clinical and , molecular genetics, November 28-30, 2016, Chicago, USA; 2nd International Conference and Exhibition on Molecular medicine and diagnostics, September 26-28, 2016 Miami, USA; The personalized medicine World Conference (PMWC) 2016, San Francisco, USA; Seventeenth International Meeting: Cell Molecular Biology  of genus Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan; 18th International Conference on Genetics and molecular biology, October 10 – 11 2016, Osaka, Japan; 13th International Congress of Human genetics, April 3-7 2016, Kyoto, Japan.

Track 7 : Metabolic Modeling

Metabolism is a vital cell procedure, and its malfunction could be a significant donor to various human sicknesses. Metabolites can function as a metabolic infirmity biomarker. Recognition of such biomarkers assumes an enormous part within the investigation of biochemical response and flagging systems. Metabolic profiling, Metabolomic and metabonomic concentrates for the foremost part which includes the multicomponent investigation of natural liquids, tissue and cell removes utilizing NMR spectroscopy and/or mass spectroscopic analysis (MS). Metabolic identification (metabolomics / metabonomics) is that the estimation in organic frameworks of the supplement of low-sub-atomic weight metabolites and their intermediates that mirror the dynamic reaction to hereditary modification and physiological, pathophysiological, and/or formative boosts. These developments in metabolomics and metabolic identification technologies have paved to the invention of many new metabolic biomarkers. Through the NIH Common Fund’s Increasing Metabolomics research capability program External web site Policy, the NIH has given over $65 million to quicken the sector of metabolomics throughout the subsequent 5 years. The target of this finance system is to propel a few center ranges, together with far reaching metabolomics asset centers, metabolomics innovation improvement, metabolomics reference principles amalgamation, getting prepared and instructive exercises in metabolomics.

Relevant Conferences:7th International Conference on Biomarkers & Clinical Research, Nov 28-30, 2016, Baltimore, USA; Sixth International Conference & Expo on Proteomics March 29-30, 2016, Atlanta, USA; Fifth International Conference on Computational Systems Biology, August 22-23, 2016 Philadelphia, USA ; 2nd  International Conference on Current Trends in Mass spectrometry from May 09-11, 2016 Chicago, USA; Sixth International Conference on Genomics & Pharmacogenomics, September 22-24, 2016, Berlin, Germany; The personalized medicine World Conference (PMWC) 2016, San Francisco, USA; Seventeenth International Meeting: Cell Molecular biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan; 18th International Conference on Genetics and molecular biology, October 10 – 11 2016, Osaka, Japan; 13th International Congress of Human Genetics, April 3-7 2016, Kyoto, Japan.

Track 8 : Clinical Metabolomics & Lipidomics

Metabolomics and lipidomics, intense apparatuses in frameworks science, expect to screen minor metabolites and its presence in organic examples. Contrasts within the species or measures of metabolites are utilized to portray phenotypes and natural reactions to annoyances (hereditary changes, ailments, or nutrient and pharmacological medications). The Thermo Scientific TSQ arrangement mass spectrometer instrument family, joined with high determination GC or UHPLC, offers unmatched versatility and affectability to chosen  particle response checking (SRM) tests for the measure of  endogenous metabolites and lipids utilizing Thermo Scientific Trace Finder and LC Quan programming. Translational Biomarker Discovery Core incorporate identifying, approving and creating the pre-clinical biomarkers for building up the locality of complaint, observant reduction stature, deciding the viability of specific remedial conventions, and regulating the selection of specific useful mediations. Connecting the implications of biomarker studies utilizing protein-protein association methodologies will facilitate with frameworks science approaches and will prompt theory era and recognizable proof of latest medication targets. Science Minister David Willetts has declared £48 million of latest speculation to store studies on ventures went for handling well-being problems.

Relevant Conferences: Second International Conference on Current Trends in Mass spectrometry analysis May 09-11, 2016 Chicago, USA; Asia Pacific Mass spectrum analysis Congress October 13-15, 2016 Malaysian capital, Kuala Lumpur; Seventh International Conference on Biomarkers & Clinical Research analysis, Nov 28-30, 2016, Baltimore, USA; Seventh International Conference and Exhibition on Analytical & Bio analytical Techniques, Sept 29-Oct 01, 2016 , Miami, USA; Second International Conference on Genetic and Protein Engineering ,November 14-16, 2016 Atlanta, USA; LIPID MAPS Annual Meeting 2016: Lipidomics Impact on Metabolic, Cancer, cardiovascular and Inflammatory Diseases, may 17 – 18, 2016, La Jolla, USA; 64th ASMS Conference, 5–9 June 2016 San Antonio, TX; 21st International Mass spectrum analysis Conference (IMSC 2016),August 20-26, 2016,Toronto, Canada; 17th International Meeting: Cell & Molecular biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan.

Track 9 : Plant & Environmental Metabolomics

Metabolomics is examination of endogenous and exogenous low mass metabolites within a cell, tissue, or bio fluid of an organic structure in presence of light of an outer aggravation. The sub-control of environmental metabolomics is utilization of metabolomic ways to analyze the connections of life forms with their surroundings. Drug metabolism system is procedure by which the body separates and changes over pharmaceutical into dynamic concoction substances. Toxicology is the branch of bio medical science that arrangements with the impacts of artificial compound used as a section of the conclusion, treatment, or antidotal action of complaint or alternative uncommon condition on the body. Plant Metabolomics is to consider the plant framework at the sub-atomic level giving non-one-sided characterization of the whole metabolite pool (metabolome) of plants beneath explicit conditions. Usage of the Metabolomics, is a very better understanding of the correlation between genes and therefore the biochemical composition of a tissue of the plant in response to its surroundings (phenotype) is obtained, and this info is further more accustomed to assess function of the gene operate (genotype). Four joint U.S. also, Japanese research analysis teams have recompensed subsidizing totaling approximately $12 million (about Yen 960 million) to grow new naturally well-disposed methods to expand the creation of renewable biofuel and reduce chemical use.

Relevant Conferences: 2nd International Conference on Current Trends in Mass spectroscopic analysis May 09-11, 2016 Chicago, USA; Asia Pacific Mass spectroscopy Congress October 13-15, 2016 Malaysian Capital, Kuala Lumpur, Malaysia; International Summit on Plant Science, October 31-November 02, 2016 Baltimore, USA San Antonio, USA; International Conference on Plant Physiology, June 09-11, 2016, Dallas, USA; International Conference on Clinical and Molecular Genetics, November 28-30, 2016, Chicago, USA; HPLC 2016, June 19-24, 2016, San Francisco, USA; 21st International Mass spectroscopic analysis Conference (IMSC 2016),August 20-26, 2016,Toronto, Canada; Plant Metabolic Engineering, July 19-24, 2016, Waterville valley, NH; 11th International Congress of  Plant Molecular Biology (IPMB), October 25-30, 2015 Foz do Iguazu, Brazil.

Track 10 : Food & Nutritional Metabolomics

Unlike the other ‘omics’ technologies (proteomics, genomics …etc.), metabolomics provides organic understanding that mirrors each individual’s one amongst a kind of hereditary distinctive mark, also as means of life, intake of routine food and surroundings. Utilizing metabolomics, scientists will quantitatively dissect non-hereditary variables that includes in post genomic and posttranscriptional modification. Nutritional metabolomics is fast developing to utilize very little atom substance identification to bolster incorporation of intake program and sustenance in complicated bio systems analysis. Nutrigenomics is the branch of nutritional genetic science and is the study of the resulted effects of food and food constituents on gene expression. Foodomics has been recently outlined as a brand new discipline that studies food and nutrition domains through the appliance of advanced omics technologies within which MS techniques are considered indispensable. Applications of Foodomics embodies the genomic, Transcriptomics, proteomic, and/or metabolomic study of foods for compound identification, credibility, and/or biomarker-detection associated with food quality or safety; the development of latest transgenic foods, food contaminants, and whole toxicity studies; new investigations on food bioactivity, food effects on human health. The University of Michigan Nutrition obesity research center (UM NORC) started in 2010, supported by the National Institute of diabetes and digestive and kidney Diseases (NIDDK). The UM NORC is one among of Twelve U.S. focuses supposed to maneuver and backing translational, multi-disciplinary exploration in ponderosity and sustenance, over the continuum of elementary science to applications in pupil (solution) and populations (public health).

Relevant Conferences: Fifth International Conference on Clinical Nutrition, San Antonio, November 28-30, 2016; USA; Sixth International Conference and Exhibition on Diet and Nutrition, August 18-20, 2016 London, UK; 2nd International Conference on lipid Science & Technology, Oct 06-08, 2016 Maimi, USA; International Conference on Environmental toxicology and Ecological Risk Assessment , August 25-26, 2016 Sao Paulo, Brazil; 2nd International Conference on livestock Nutrition, July 21-22, 2016 Brisbane, Australia; Tenth Congress of the International Society of Nutrigenetics & Nutrigenomics (ISNN), May 22-26, 2016, Tel Aviv, Israel; Max Rubner Conference 2016: Food Metabolomics, Oct 10-12,2016, Germany.

Track 11: Metabolomic devices

Metabolomics, alternately metabolomics, a rising field of biochemical exploration, could be a reciprocal procedure to the genomics, Transcriptomics, and proteomics. Direct quantitative estimations of metabolite expressions in pee, serum, plasma, and tissue are very crucial for the investigation of organic procedures in typical and malady states. Beyond the number of metabolites in a natural example is intensive partition science assumes an essential part in metabolomic analysis. Atomic attractive reverberation (NMR) spectrscopy is especially capable for centered investigation since its quantitative, reproducible, and appropriate for advanced examples, as an example, blood, pee, or tissue removes with much zero getting ready. Thermo Fisher, AB SCIEX, and Bruker likewise provide instruments for imaging MS, in addition known as MALDI imaging. To fulfill difficulties of search ability and knowledge reconciliation, the metabolomics cluster incorporates a few activities to make up info vaults. Cases are Metabolites within the UK, bolstered by the European COSMOS (Coordination of Standards in Metabolomics) association that’s making metabolomics info norms, and Metabolomics work bench, which suggests being the database for NIH-subsidized metabolomics ventures. Thermo Fisher groups up with Fiehn on, a free community database that features actual and virtual MS spectra with unknown compounds to be annotated as they’re known.

Relevant Conferences: 2nd International Conference on Current Trends in Mass spectroscopic analysis May 09-11, 2016 Chicago, USA; Asia Pacific Mass spectroscopic analysis Congress October 13-15, 2016 National capital, Kuala Lumpur, Malaysia; Seventh International Conference on Biomarkers & Clinical Research analysis, November 28-30, 2016, Baltimore, USA; Seventh International Conference and Exhibition on Analytical & Bio analytical Techniques, Sept 29-Oct 01, 2016 , Miami, USA; 2nd International Conference on Genetic and Protein Engineering ,November 14-16, 2016 Atlanta, USA; Lipid MAPS Annual Meeting 2016: Lipidomics Impact on Metabolic, Cancer, cardiovascular and Inflammatory Diseases, May 17- 18, 2016, La Jolla, USA; Sixty fourth ASMS Conference, 5–9 June 2016 city, TX; twenty first International Mass spectroscopy analysis Conference (IMSC 2016),August 20-26, 2016,Toronto, Canada; Seventeenth International Meeting: Cell & Molecular biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan.

Track 12 : Analytical Platforms in Metabolomics

In metabolomics, real endeavors are the resources into the advancement of appropriate scientific methodologies. Metabolomics, the foremost youngest field within the ‘omics family, is growing quickly. Developing directly behind genomics, Transcriptomics, and proteomics, metabolomics is the intensive examination of very little particle metabolites. In subsequent to most metabolites are made by enzymatic proteins that outcome from quality expression, and metabolites provide creatures their biochemical attributes, the metabolome links genotype with phenotypic constitution. Metabolomics is so far growing, however, as merchants regulate division and discovery instruments to fulfill its difficulties and also the examination cluster deciphers and incorporates the fascinating data they’re gaining. The late fast advancement of a scope of fact-finding stages, as well as GC, HPLC, UPLC, CE coupled to MS and NMR spectrum analysis, might empower partition, identification, portrayal and analysis of such metabolites and connected metabolic pathways. Proceeded with improvement of those diagnostic stages can quicken so much reaching use and coordination of metabolomics into frameworks science. NIH Awards $1.6M to Fund microRNA Biomarker analysis in Cancer, Alzheimer’s. The Bill and Melinda Gates Foundation these days declared $7.7 million in finance for ten new grants to spot biomarkers for the diagnosis of Tuberculosis (TB) in low-resource settings.

Relevant Conferences: 2nd International Conference on Current Trends in Mass spectrometry May 09-11, 2016 Chicago, USA; Asia Pacific Mass spectrometryCongress October 13-15, 2016 Malaysian Capital, Kuala Lumpur, Malaysia; Seventh International Conference on Biomarkers &  Clinical analysis, Nov 28-30, 2016, Baltimore, USA; Seventh International Conference and Exhibition onAnalytical & Bio analytical Techniques, Sept 29-Oct 01, 2016 , Miami, USA; 2nd International Conference on Genetic and Protein Engineering ,November 14-16, 2016 Atlanta, USA; Lipid MAPS Annual Meeting 2016: Lipidomics Impact onMetabolic, Cancer, Cardiovascular and Inflammatory Diseases, May 17 – 18, 2016, La Jolla, USA; 64th ASMS Conference, 5–9 June 2016 San Antonio, TX; 21st International Mass spectrometry Conference (IMSC 2016),August 20-26, 2016,Toronto, Canada; 17th International Meeting: Cell & Molecular Biology of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan.

Track 13 : Data Analysis & Systems Biology

Systems biology is a field within biology aimed at understanding biological processes at Systems biology is field with in the biology aimed towards understanding biological processes at the systems level and rising from dynamic interactions of individual parts operational at multiple spatiotemporal scales. Systems biology considers organic Systems by with efficiency bothering them (organically, hereditarily, or artificially); observant the standard, protein, and academic pathway reactions; incorporating these information; eventually, coming up with numerical models that portray the structure of the framework and anticipate its reaction to individual irritations. Integrated “omics” approaches have created energizing open doors for Systems science and different organic examines. Decreases within the expense of manufacturing genomic info have created DNA sequencing, RNA-Seq, ad high-throughput screening an undeniably imperative piece of biomedical exploration. The National Institute of medicine Sciences (NIGMS), The organization of the National Institutes of Health (NIH) supporting basic analysis and research getting ready, declared shortly past that it’d build up 2 new divisions — together with one targeting biomedical innovation, bioinformatics, and computational biology  – – as a part of a reorganization that includes the dissolution of the NIH National Center for analysis Resources (NCRR) that has had a history of supporting scientific computing.

Relevant Conferences:7th International Conference on Biomarkers & Clinical analysis, Nov 28-30, 2016, Baltimore, USA; Sixth International Conference & expo on Proteomics March 29-30, 2016, Atlanta, USA; fifth International Conference on Computational Systems Biology , August 22-23, 2016 Philadelphia, USA ; second  International Conference on Current Trends in Mass spectrometry May 09-11, 2016 Chicago, USA; sixth International Conference on Genomics & Pharmacogenomics, Sep 22-24, 2016, Berlin, Germany; The personalized medication World Conference (PMWC) 2016, San Francisco, USA; seventeenth International Meeting: Cell molecular biology of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan; Eighteenth International Conference on Genetics and Molecular biology, October 10 – 11, 2016, Osaka, Japan; Thirteenth International Congress of Human Genetics science, April 3-7 2016, Kyoto, Japan.

Track 14 : Enhancing Analytical Approaches

The speedily growing space of “metabolomics,” during which an oversized range of metabolites from body fluids, cells or tissue area unit detected quantitatively, in a very single step, guarantees vast potential for huge count of disciplines as well as early illness diagnosing, therapy observance, systems biology, drug discovery and nutritional science. As a result of its ability to sight an oversized range of metabolites in intact biological samples reproducibly and quantitatively, nuclear resonance (NMR) spectrum analysis has emerged jointly of the foremost powerful analytical techniques in metabolomics. Metabolome, Agilent Technologies, Thermo Scientific, Chenomx and Human Metabolome Technologies, Bio crates Life Sciences, and Metanomics is the most leaders within the metabolomics area. They’re active in many aspects of this market: medically special diagnose development, identification services, tutorial collaborations, and even acquisitions. Through the NIH Common Fund’s Increasing Metabolomics analysis capability program External web site Policy, the NIH has committed over $65 million to accelerate the sector of metabolomics over following 5 years. The goal of this funding program is to advance many core areas, as well as comprehensive metabolomics resource cores, metabolomics technology development, metabolomics reference standards synthesis, and coaching and academic activities in metabolomics.

Relevant Conferences: Asia Pacific Mass spectrometry Congress Oct 13-15, 2016 Malaysian capital, Kuala Lumpur Malaysia; Seventh International Conference on Biomarkers & Clinical analysis, November 28-30, 2016, Baltimore, USA; 2nd International Conference on Current Trends in Mass Spectrometry analysis May 09-11, 2016 Chicago, USA; Seventh International Conference and Exhibition on Analytical & Bio analytical Techniques, Sept 29-Oct 01, 2016 , Miami, USA; 2nd International Conference on Genetic and protein Engineering ,November 14-16, 2016 Atlanta, USA; Macromolecule MAPS Annual Meeting 2016: Lipidomics Impact on Metabolic, Cancer, Cardiovascular and Inflammatory Diseases, May 17 – 18, 2016, La Jolla, USA; Sixty fourth ASMS Conference, 5–9 June 2016 city, TX; Twenty first International Mass spectroscopic analysis Conference (IMSC 2016),August 20-26, 2016,Toronto, Canada; Seventeenth International Meeting: Cell & molecular biology Of Chlamydomonas, June 26 – July 1 2016, Kyoto, Japan.

Track 15 : Case Reports 

Case reports are a vital direct wellspring of confirmation in pharmaceutical and a device regularly utilized as a part of practice to trade data and create a more extended quest for proof. A decent case report will be clear about the significance of the perception being accounted for. A good case report will be clear about the importance of the observation being reported. In addition to the “evidence of what happened”, single or multiple cases are an important basis for further and more advanced research on diagnosis, treatment adequacy, reasons and results of ailment. Case reports might be first to give signs in distinguishing another ailment or unfriendly wellbeing impact from a presentation. Case reports must be authentic, understandable, educational and clinically interesting to an international audience of surgeons, trainees and researchers in all surgical subspecialties, as well as clinicians in related fields.

Relevant Conferences: International Conference on Case Reports, March 31-April 02, 2016 Valencia, Spain; 2nd  International Meeting on Clinical Case Reports , April 18-20, 2016 Dubai, UAE; 3rd Experts Meeting on Medical Case Reports , May 09-11, 2016 New Orleans, USA; 2nd International Conference and Exhibition on Molecular Medicine and Diagnostics, September 26-28, 2016 Miami, USA; 4th International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics, September 19-21 2016, Phoenix, USA; Autumn Conference 2016 Case Report  discussion, October 15-16,2016, Birmingham, UK; 17th International Meeting: Cell & Molecular Biology Of Chlamydomonas, June 26-July 1 2016, Kyoto, Japan; 13th International Congress of Human Genetics, April 3-7 2016, Kyoto, Japan; IMPAKT  Breast Cancer Conference,  May 12-14 2016, Brussels, Belgium; International Conference on General Medicine & Dental Practise, Nov 7-9, 2016 Istanbul, Turkey; The Personalized Medicine World Conference (PMWC), May 11-13, 2016, San Francisco, USA;


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