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This Is America’s Richest Zip Code

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Reporter and Curator: Dr. Sudipta Saha, Ph.D.

 

Hepatitis B virus can cause serious, long-term health problems, such as liver disease and cancer, and can spread from mother-to-child during delivery. According to the latest estimates from the World Health Organization (WHO), approximately 257 million people in 2015 were living with the virus. Countries in Asia have a high burden of hepatitis B. There is no cure, and antiviral drugs used to treat the infection usually need to be taken for life.

 

To prevent infection, WHO recommends that all newborns receive their first dose of hepatitis B vaccine within 24 hours of delivery. Infants born to hepatitis B-infected mothers are also given protective antibodies called hepatitis B immune globulin (HBIG). However, mother-to-child transmission can still occur in women with high levels of virus in their blood, as well as those with mutated versions of the virus.

 

Tenofovir disoproxil fumarate (TDF), an antiviral drug commonly prescribed to treat hepatitis B infection, does not significantly reduce mother-to-child transmission of hepatitis B virus when taken during pregnancy and after delivery, according to a phase III clinical trial in Thailand funded by the National Institutes of Health. The study tested TDF therapy in addition to the standard preventative regimen — administration of hepatitis B vaccine and protective antibodies at birth — to explore the drug’s potential effects on mother-to-child transmission rates. The results appear in the New England Journal of Medicine.

 

The present study was conducted at 17 hospitals of the Ministry of Public Health in Thailand. It screened more than 2,500 women for eligibility and enrolled 331 pregnant women with hepatitis B. The women received placebo (163) or TDF (168) at intervals from 28 weeks of pregnancy to two months after delivery. All infants received standard hepatitis B preventatives given in Thailand, which include HBIG at birth and five doses of the hepatitis B vaccine by age 6 months (which differs from the three doses given in the United States). A total of 294 infants (147 in each group) were followed through age 6 months.

 

Three infants in the placebo group had hepatitis B infection at age 6 months, compared to zero infants in the TDF treatment group. Given the unexpectedly low transmission rate in the placebo group, the researchers concluded that the addition of TDF to current recommendations did not significantly reduce mother-to-child transmission of the virus.

 

According to the study, the clinical trial had enough participants to detect statistical differences if the transmission rate in the placebo group reached at least 12 percent, a rate observed in previous studies. Though the reasons are unknown, the researchers speculate that the lower transmission rate seen in the study may relate to the number of doses of hepatitis B vaccine given to infants in Thailand, lower rates of amniocentesis and Cesarean section deliveries in this study, or the lower prevalence of mutated viruses that result in higher vaccine efficacy in Thailand compared to other countries.

 

References:

 

https://www.nih.gov/news-events/news-releases/antiviral-drug-not-beneficial-reducing-mother-child-transmission-hepatitis-b-when-added-existing-preventatives

 

https://www.ncbi.nlm.nih.gov/pubmed/29514030

 

https://www.ncbi.nlm.nih.gov/pubmed/29514035

 

https://www.ncbi.nlm.nih.gov/pubmed/25240752

 

https://www.ncbi.nlm.nih.gov/pubmed/28188612

 

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2018 Annual World Medical Innovation Forum Artificial Intelligence April 23–25, 2018 Boston, Massachusetts  | Westin Copley Place

https://worldmedicalinnovation.org/

https://www.youtube.com/channel/UCauKpbsS_hUqQaPp8EVGYOg

Announcement

Aviva Lev-Ari, PhD, RN,

Founder and Director of LPBI Group will be in attendance covering the event in REAL TIME

@pharma_BI

@AVIVA1950

On 5/2015

4/2018

All TWEETS from LPBI’s Twitter.com handles at

#WMIF18

@pharma_BI

@AVIVA1950

Monday, April 23, 2018

 

7:00 am – 8:00 am
GE Foyer
7:00 am – 8:00 am
Nuance Foyer
8:00 am – 11:30 am
NVIDIA Ballroom
First Look: The Next Wave of AI Breakthroughs in Health Care

Early career Harvard Medical School investigators kick-off the 2018 World Medical Innovation Forum with rapid fire presentations of their high potential new technologies. Nineteen rising stars from Brigham Health and Massachusetts General Hospital will give ten-minute presentations highlighting their discoveries and insights that will disrupt the field of artificial intelligence. This session is designed for investors, leaders, donors, entrepreneurs and investigators and others who share a passion for identifying emerging high-impact technologies. To view speakers and topics, click here.

Moderator: Trung Do
  • VP, Business Development, Innovation, PHS
Moderator: Clare Tempany, MD
  • Vice Chair of Research at the Department of Radiology, BWH; Ferenc Jolesz MD Professor of Radiology, HMS
11:45 am – 1:00 pm
3rd Floor and 7th Floor
Discovery Café Workshops

Lunch with Top Leadership from across Partners HealthCare and Industry.

Seven intensive workshops addressing cutting-edge artificial intelligence topics. To view topics and speakers, click here

1:00 pm – 1:20 pm
1:20 pm – 1:45 pm
NVIDIA Ballroom
Opening Remarks
  • Governor of the Commonwealth of Massachusetts
  • Chief Academic Officer, PHS; Laurie Carrol Guthart Professor of Medicine, Academic Dean for Partners, HMS; 2018 Forum Co-Chair
  • CEO, PHS
1:45 pm – 2:25 pm
NVIDIA Ballroom
Reflecting on the Impact of AI at the Bed and the Bench: Chairs Roundtable

Senior clinical leaders, current and past Forum Chairs, will share perspectives on the range of impact of AI on clinical practice. Discussion will highlight the rapid evolution of AI as a practical clinical tool and short and mid-term prospects for adoption in cancer, cardiovascular and neurological care.

Moderator: Sue Siegel
  • CIO and CEO, Business Innovations, GE
  • Chief Data Science Officer, PHS; Vice Chairman, Radiology, MGH; Associate Professor, Radiology, HMS
  • Chief Academic Officer, PHS; Laurie Carrol Guthart Professor of Medicine, Academic Dean for Partners, HMS; 2018 Forum Co-Chair
  • Vice Chair for Scientific Innovation, Department of Medicine, BWH; Chief Executive, One Brave Idea, BWH; Associate Professor of Medicine, HMS; 2017 Forum Co-Chair
  • Chief Clinical Officer, PHS; Professor of Medicine, HMS; 2018 Forum Co-Chair
  • Chief, Cardiology Division, MGH; Professor of Medicine, HMS; 2017 Forum Co-Chair
2:25 pm – 3:15 pm
NVIDIA Ballroom
Can AI Based Drug Development Feed A Hungry Pipeline?

Given the scarcity of late-stage assets, prolonged timelines and enormous costs of bringing drugs to market, AI-based approaches to target discovery, drug design and drug repurposing hold significant promise to positively disrupt the existing R&D paradigm.

  • Chief Data Officer, Broad Institute; Cardiologist, BWH; Venture Partner, Google Ventures
  • CEO, Exscientia
  • Director, Center for Genomic Medicine, MGH; Ofer and Shelly Nemirovsky MGH Research Scholar; Associate Professor of Medicine, HMS
  • EVP and CSO, R&D, Bristol-Myers Squibb
  • CEO, BERG
  • SVP, Strategy, Commercialization & Innovation, Amgen
3:15 pm – 4:05 pm
NVIDIA Ballroom
Smart EHRs: AI for All

The first wave of EHR adoption has focused primarily on digitizing the patient record – with a more recent focus on building interactive clinical decision support capabilities. Development and implementation of CDS applications currently  requires  clinical staff to observe trends in data, develop protocols to act on these trends and work with technical staff to codify the logic into executable form. As NLP and computer vision capabilities become more advanced, algorithms will identify and propose actions reflecting patterns in the data. The panel will discuss existing challenges and whether AI technology will ultimately support an unsupervised learning approach in the EHR to identify trends and possible responses at both the patient and population level?

  • SVP and CMO, MGH
  • CEO, Health Catalyst
  • Director, Analytics & Machine Learning, Epic
  • President, Digital, Persistent Systems
  • CEO, Picnic Health
  • CEO, Wolters Kluwer Health
4:05 pm – 4:55 pm
NVIDIA Ballroom
AI and the Cost of Trials: The Impact of Real World and Real Time Evidence

AI based approaches to conduct faster and more efficient clinical trials are beginning to emerge. Current approaches include applying predictive tools to perform more targeted patient recruitment and more accurate eligibility assessment. Panelists will discuss timelines for AI technology to have a measurable effect on trial cost and time to conduct the trial. Bottlenecks to applying this technology at scale and whether there will be a measurable effect on the cost of bringing drugs to market over the next decade will also be examined.

  • Partner, Google Ventures; Instructor in Medicine, BWH
  • CMO, CSO & SVP Oncology, Flatiron Health
  • VP, Research IT, Eli Lilly and Company
  • CEO, GNS Healthcare
  • CEO, BenevolentAI
  • Senior Advisor, R&D, Bayer
  • Executive Director, Clinical Trials Office, PHS; Associate Professor of Medicine, HMS
5:00 pm – 6:00 pm
Nuance Foyer

Tuesday, April 24, 2018

 

7:15 am – 7:50 am
Nuance Foyer
7:50 am – 8:00 am
NVIDIA Ballroom
Opening Remarks
  • Chief Innovation Officer, PHS; President, Partners HealthCare International, PHS
8:00 am – 8:50 am
NVIDIA Ballroom
Will AI Bend the Cost and Access Curve

Historical barriers have driven increased medical costs and decreasing access since the 1960s. The “Iron Triangle of Healthcare” continues to represent a tenuous balance of quality, cost and accessibility – economists have lamented attempts to optimize one characteristic at the expense of the others. The accumulation of innovations in care delivery (e.g. shift to lower cost providers and settings), population management, value based reimbursement and hospital administration are having a measurable effect. Can AI based technologies accelerate the pace of innovation and finally bend the cost and access curves in the US?

Moderator: Timothy Ferris, MD
  • CEO, MGPO
  • SVP and CMO, Humana
  • CEO, Cyft, Inc.
  • Vice Chairman, Investment Banking and Managing Director, Lazard Freres
8:50 am – 9:40 am
NVIDIA Ballroom
Drug Therapy Redefined Through Machine Learning

The drug development process is highly complex and has many drivers. The panel will discuss the strategic impact of AI on the entire process and the implications for healthcare overall. How will the combination of factors – research strategy, drug development, regulatory approvals, reimbursement and clinical effectiveness – be influenced by the implementation of AI. Panelists will discuss short and mid-term prospects and whether AI will ultimately lead to a restructuring of the pharma model to develop new therapies.

  • Partner, Atlas Venture
  • President, Novartis Institutes for Biomedical Research
  • CSO, Relay Therapeutics
  • SVP, Global Head of Data Sciences, Johnson & Johnson
  • CSO, Datavant
  • Global Head of Digital and Personalized Health Care Partnering, Roche
9:40 am – 10:10 am
NVIDIA Ballroom
1:1 Fireside Chat: Atul Gawande, MD
Introduction by: John Fish
  • CEO, Suffolk; Chairman of Board Trustees, Brigham Health
  • President, Brigham Health; Professor of Medicine, HMS
  • Executive Director, Ariadne Labs; Samuel O. Thier Professor of Surgery, HMS; Surgeon, BWH
10:10 am – 10:25 am
Nuance Foyer
10:25 am – 11:15 am
NVIDIA Ballroom
Data Engineering in Healthcare: Liberating Value

The promise of machine learning and big data in in healthcare seems boundless – but healthcare data is massive and complex, and organizing and managing this data is the first step to an AI-empowered healthcare system.  Technology giants are investing in solutions to overcome these data engineering challenges, but with many visions of the future of healthcare data jockeying for dominance, what will the future of healthcare data really look like?  Can we finally liberate the value of data for patient care? And how will it happen?

Moderator: Mark Michalski, MD
  • Executive Director, MGH & BWH CCDS
  • ‎Director of Healthcare Research, Microsoft Research
  • VP and Global CTO, Sales, Dell EMC
  • SVP and CMO, Qualcomm Life
  • VP, Healthcare, Google Cloud
  • Chief Research Information Officer, PHS; Associate Professor of Neurology, HMS
  • CTO, Cognitive Collaboration Group, Cisco
11:15 am – 11:45 am
NVIDIA Ballroom
1:1 Fireside Chat: Jensen Huang, CEO, NVIDIA
Introduction by: Scott Sperling
  • Co-President, Thomas H Lee Partners; Chairman of the Board of Directors, PHS
  • Chief Data Science Officer, PHS; Vice Chairman, Radiology, MGH; Associate Professor, Radiology, HMS
  • CEO, NVIDIA
12:00 pm – 1:00 pm
GE Ballroom
12:30 pm – 1:00 pm
GE Ballroom
1:1 Fireside Chat: Paul Ricci, Former Chairman and CEO of Nuance Communications
Introduction by: Cathy Minehan
  • Managing Director, Arlington Advisory Partners; Chairman, Board of Trustees, MGH
Moderator: James Brink, MD
  • Chief, Department of Radiology, MGH; Juan M. Taveras Professor of Radiology, HMS
  • Former Chairman and CEO, Nuance Communications
1:00 pm – 1:10 pm
1:10 pm – 2:00 pm
NVIDIA Ballroom
AI and Gene Sequencing

Gene sequencing technology has evolved considerably over the last 10 years, dramatically decreasing the cost to sequence a human genome. As the costs associated with the technical assay continue to decrease, data interpretation and reporting has become the new bottleneck. Can AI and ML based approaches be applied to better understand how genetic mutations play a role in diseases like cancer – where the high rate of mutation makes treatment challenging? And will continued democratization of genetic information help to accelerate the pace of innovation in the field?

Moderator: Heidi Rehm, PhD
  • Chief Laboratory Director, Laboratory for Molecular Medicine, PHS Personalized Medicine; Associate Professor of Pathology, BWH and HMS
  • Executive Director, Worldwide R&D, Pfizer
  • Director, Bioinformatics Program, Cancer Center and Department of Pathology, MGH; Director, Institute Member, Broad Institute; Associate Professor of Pathology, HMS
  • Director, Computational Pathology and Director, Technology Development, Center for Integrated Diagnostics, MGH; Assistant Professor, Pathology, HMS
  • CEO, Freenome
  • SVP, Product Development, Illumina, Inc.
2:00 pm – 2:50 pm
NVIDIA Ballroom
Tangible Returns on the AI Value Proposition

Fueled by billions in venture investments, hundreds of new companies have emerged worldwide to develop and apply AI in health care. Beyond the US, China’s high AI priority has resulted in a vast array of technology driven start-ups. Global investors will discuss which area of machine learning will have the earliest meaningful impact? How do investors critically assess differentiation in such a crowded field? How are investment priorities set among the many divergent categories where AI will take hold?

Moderator: Meg Tirrell
  • Reporter, CNBC
  • Managing Director, Santé Ventures
  • VP, Venture, Innovation, PHS
  • Partner, Polaris Partners
  • Partner, Andreessen Horowitz
  • Managing Director, Northern Light Venture Capital
2:50 pm – 3:40 pm
NVIDIA Ballroom
CEO Roundtable: The AI Opportunity as Foundational Change

Chief executives share perspectives on the impact of AI on their respective companies and industry segments. How prominently does AI figure into current investment strategies? And how are they measuring return on existing investments in AI? Panelist will be asked to take a position on whether AI is a truly transformational technology.

Moderator: Peter Slavin, MD
  • President, MGH
  • Chief Innovation Officer, GE Healthcare
  • CEO, Philips
  • CEO, Vertex
  • CEO, Siemens Healthineers
3:40 pm – 3:50 pm
NVIDIA Ballroom
Announcement of IDG Awardees
  • Chair, Department of Radiology, BWH; Philip H. Cook Professor of Radiology, HMS
  • Chief, Department of Radiology, MGH; Juan M. Taveras Professor of Radiology, HMS
3:50 pm – 4:40 pm
NVIDIA Ballroom
Regulating AI in Healthcare, Requirements and Challenges

The increasing application of AI in health products puts pressure on the historical model of regulation – among them the agile development cycles and continuous learning environment that support AI / machine learning based algorithms. Panelists will discuss the regulatory approaches including the FDA’s recently announced Software Precertification pilot program.

Moderator: Michael Jaff, DO
  • President, NWH, PHS, Professor of Medicine, HMS
  • CEO, Arterys
  • Chief Regulatory Officer, Sanofi
  • VP and GM, Healthcare Digital Solutions, GE Healthcare
  • Associate Director for Digital Health, FDA
4:40 pm – 5:30 pm
NVIDIA Ballroom
AI in Hospital Environments: The Learning Provider

Health systems are actively evaluating strategies to drive efficiency throughout hospital operations. The deployment of AI based technologies to automate organizational tasks (e.g. medical coding / billing, prior authorizations) and optimize resource utilization (e.g. smart scheduling, no-show prediction) promises to help hospital systems adapt to changing macro-economic factors. This panel will discuss the role of AI in hospital operations and assess various approaches to reduce healthcare administration costs and increase efficiency.

Moderator: Adam Landman, MD
  • VP and CIO, Brigham Health
  • Executive Director, IT, Personalized Medicine, PHS
  • Partner, Optum Ventures
  • CEO, Change Healthcare
  • CEO, Qventus
  • Co-Founder, Director, PokitDok
5:30 pm – 6:30 pm
GE Foyer

Wednesday, April 25, 2018

 

7:00 am – 7:30 am
Nuance Foyer
7:30 am – 8:20 am
NVIDIA Ballroom
Reconceiving Medical Devices in an AI Dominated Environment

Medical device companies are focused on developing smaller, faster and smarter devices. New technologies will enhance the function of medical devices throughout patient care. Leveraging AI technology to more effectively interact with patients and inform / facilitate outcomes enables smart devices that can learn and improve performance over time. The nature of AI panel based devices, the challenges inherent in developing them and how such devices can evolve over the next 5 years and beyond will be examined.

Moderator: Pat Fortune, PhD
  • VP, Market Sectors, Innovation, PHS
  • CEO, Bay Labs
  • SVP, Chief Medical and Scientific Officer, Medtronic
  • Founder and CEO, Butterfly Network
  • Associate Chief, Cardiology Division, MGH; Professor of Medicine, HMS
8:20 am – 8:50 am
NVIDIA Ballroom
Fireside Chat: Seema Verma, Administrator, Centers for Medicare and Medicaid Services
Moderator: Gregg Meyer, MD
  • Chief Clinical Officer, PHS; Professor of Medicine, HMS; 2018 Forum Co-Chair
  • Administrator, Centers for Medicare and Medicaid Services
8:50 am – 9:20 am
NVIDIA Ballroom
Fireside Chat: Paying for AI: Thinking Strategically About Reimbursements and Acceptance

Understanding how AI will be absorbed into a highly defined payment system is crucial to determining the rate and breadth that the technology will play in health care in the next decade. Two senior leaders will share their perspectives on how the technology will be paid for and what mechanisms will be used to arbitrate the scope and timing of those payments.

Moderator: Peter Markell
  • EVP Administration and Finance, CFO and Treasurer, PHS
  • CEO, BCBS of North Carolina
  • CEO, OptumInsight & Enterprise Growth Officer, Optum
9:20 am – 9:50 am
NVIDIA Ballroom
1:1 Fireside Chat: Vasant Narasimhan, MD, CEO, Novartis
Moderator: Gregg Meyer, MD
  • Chief Clinical Officer, PHS; Professor of Medicine, HMS; 2018 Forum Co-Chair
  • CEO, Novartis
9:50 am – 10:40 am
NVIDIA Ballroom
Machine Learning in Image Analysis: A Diagnostician’s Best Friend…or Replacement?

Diagnostic imaging is among the clinical fields receiving the greatest attention in the early stages of AI in healthcare. Even in this initial phase it appears that the technology may have profound effects on one of the most resource intensive fields in medicine. Panelists will consider the broad implications as well as topics such as how will role of radiologists evolve? Will AI tools ever become advanced enough to make decisions autonomously within the clinical workflow?

Moderator: Giles Boland, MD
  • Chair, Department of Radiology, BWH; Philip H. Cook Professor of Radiology, HMS
  • CEO, PathAI
  • VP, Medical Imaging Technology, Siemens Healthineers
  • Co-Founder and Chairman, Zebra Medical Vision
  • CEO, GE Healthcare Imaging
  • Chief, Breast Imaging Division, MGH; Professor of Radiology, HMS
10:40 am – 10:50 am
Nuance Foyer
10:50 am – 11:20 am
NVIDIA Ballroom
1:1 Fireside Chat: John Kelly, PhD, SVP, Cognitive Solutions and Research, IBM
Moderator: James Noga
  • VP and CIO, PHS
  • SVP, Cognitive Solutions and Research, IBM
11:20 am – 12:10 pm
NVIDIA Ballroom
Illuminating the Path to Clinician Empowerment

The sacred exchange between patient and clinician at the heart of medicine is increasingly under duress driven by a range of factors. Increasing clinician burnout is recognized as among the many negative consequences of this trend. Panelists will discuss how AI may improve the quality of the patient encounter, clinician workflow and ultimately clinician quality of life. Panelist will discuss how the new technology can meet these objectives when earlier information based technologies may have exacerbated the challenge.

Moderator: Sree Chaguturu, MD
  • VP, Population Health Management, PHS
  • SVP, New Business Development, Healthcare Division, Nuance
  • Chief Health Strategy Officer, US Health & Life Sciences, Microsoft
  • CEO, Robin AI
  • Chief Medical Information Officer, MGPO
12:10 pm – 1:10 pm
NVIDIA Ballroom
Disruptive Dozen: 12 AI Technologies That Will Reinvent Care

The culture of innovation throughout Partners HealthCare naturally fosters robust discussions about new “disruptive” technologies and which ones will have the biggest impact on health care. The Disruptive Dozen was created to identify and rank the technologies that Partners faculty feel will break through over the next decade to significantly improve health care. This year, the Disruptive Dozen focuses on relevant advances and opportunities in artificial intelligence (AI).

  • Director of Research Strategy and Operations, MGH & BWH CCDS; Associate Professor, Radiology, HMS
  • Chief Data Science Officer, PHS; Vice Chairman, Radiology, MGH; Associate Professor, Radiology, HMS
1:10 pm – 1:15 pm
NVIDIA Ballroom
Last Look
  • Chief Data Science Officer, PHS; Vice Chairman, Radiology, MGH; Associate Professor, Radiology, HMS
  • Chief Academic Officer, PHS; Laurie Carrol Guthart Professor of Medicine, Academic Dean for Partners, HMS; 2018 Forum Co-Chair
  • Chief Clinical Officer, PHS; Professor of Medicine, HMS; 2018 Forum Co-Chair

*Panels and speakers are subject to change.

Highlighted Presenters

Jensen Huang

CEO, NVIDIA

Vasant Narasimhan MD

CEO, Novartis

Paul Ricci

Former Chairman and CEO, Nuance Communications

Atul Gawande MD

Executive Director, Ariadne Labs; Samuel O. Thier Professor of Surgery, HMS; Surgeon, BWH

Seema Verma

Administrator, Centers for Medicare and Medicaid Services

Sue Siegel

CIO and CEO, Business Innovations, GE

Frans van Houten

CEO, Philips

Bernd Montag PhD

CEO, Siemens Healthineers

Terri Bresenham

Chief Innovation Officer, GE Healthcare

John Kelly PhD

SVP, Cognitive Solutions and Research, IBM

Karim Karti

CEO, GE Healthcare Imaging

Jonathan Rothberg PhD

Founder and CEO, Butterfly Network

Jay Bradner MD

President, Novartis Institutes for Biomedical Research

Colin Hill

CEO, GNS Healthcare

Amy Abernethy MD, PhD

CMO, CSO & SVP Oncology, Flatiron Health

Thomas Lynch MD

EVP and CSO, R&D, Bristol-Myers Squibb

Diana Nole

CEO, Wolters Kluwer Health

Roy Beveridge MD

SVP and CMO, Humana

Fabien Beckers PhD

CEO, Arterys

Peter Orszag PhD

Vice Chairman, Investment Banking and Managing Director, Lazard Freres

Georgia Papathomas PhD

SVP, Global Head of Data Sciences, Johnson & Johnson

Punit Soni

CEO, Robin AI

Dan Burton

CEO, Health Catalyst

Jean-François Formela MD

Partner, Atlas Venture

Patrick Conway MD

CEO, BCBS of North Carolina

Jackie Hunter PhD

CEO, BenevolentAI

Greg Moore MD, PhD

VP, Healthcare, Google Cloud

Noga Leviner

CEO, Picnic Health

Leonard D’Avolio PhD

CEO, Cyft, Inc.

Vijay Pande PhD

Partner, Andreessen Horowitz

Iain Buchan MD

‎Director of Healthcare Research, Microsoft Research

Mark Murcko PhD

CSO, Relay Therapeutics

Andrew Hopkins

CEO, Exscientia

Gabriel Otte

CEO, Freenome

Joseph Scheeren PharmD

Senior Advisor, R&D, Bayer

Susan Tousi

SVP, Product Development, Illumina, Inc.

Lisa Maki

Co-Founder, Director, PokitDok

Timothy Tuttle PhD

CTO, Cognitive Collaboration Group, Cisco

Seth Hain

Director, Analytics & Machine Learning, Epic

Featured Speakers

Note: speakers are subject to change.

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HealthCare focused AI Startups from the 100 Companies Leading the Way in A.I. Globally

Reporter: Aviva Lev-Ari, PhD, RN

 

These 100 Companies Are Leading the Way in A.I.

By Nicolas Rapp and Brian O’Keefe

January 8, 2018

Whether you fear it or embrace it, the A.I. revolution is coming—and it promises to have an enormous impact on the world economy. PwC estimates that artificial intelligence could add $15.7 trillion to global GDP by 2030. That’s a gargantuan opportunity. To identify which private companies are set to make the most of it, research firm CB Insights recently released its 2018 “A.I. 100,” a list of the most promising A.I. startups globally (grouped by sector in the graphic above). They were chosen, from a pool of over 1,000 candidates, by CB Insights’ Mosaic algorithm, based on factors like investor quality and momentum.

  • China’s Bytedance leads in funding with $3.1 billion, but
  • 76 of the 100 startups are U.S.-based.

 

Observations:

  • A Focus on Health Care and Life Sciences Sectors show that of 100 AI start ups, only 9 are in Health Care that made the cut from the initial 1,000 start ups considered for inclusion in the classification by Sector done by CB Insights, using CB Insights’ Mosaic algorithm
  • Three US Based AI start ups in Health Care have already funding exceeding $100 Million:
  1. Flatiron Health – $313 Million
  2. Recursion Pharmaceuticals – $118.62 Million
  3. Zymergen – $174 Million
  • That list does not include Health Care related AI investments in Non start ups.
  • In the US, Non start ups Health Care related AI investments include the following:

Veterans Health Administration – Veterans Affairs

NIH

Health Care HMOs:

Kaiser Permanenete, Partners

Health Care Insurance Companies:

United HealthCare, Blue Cross Blue Shield

Academic Hospitals:

MGH, Duke Medical Center, Stanford Medical Center,

2018 Annual World Medical Innovation Forum

Artificial Intelligence

April 23–25, 2018
Boston, Massachusetts  |  Westin Copley Place
For inquiries: WMIF@partners.org

The World Medical Innovation Forum is a global gathering of more than 1,000 senior health care leaders in the heart of Boston. It was established to respond to the intensifying transformation of health care and its impact on innovation. The Forum is rooted in the belief that no matter the magnitude of that change, the center of health care needs to be a shared, fundamental commitment to collaborative innovation – industry and academia working together to improve patient lives.

ARTIFICIAL INTELLIGENCE
APRIL 23–25, 2018
BOSTON, MA • UNITED STATES

COMPANY

COUNTRY SECTOR

FUNDING

($ Mil.)

AiCure

U.S. HEALTHCARE

30.74

Arterys

U.S. HEALTHCARE

42

babylon

U.K. HEALTHCARE

85

Flatiron Health

U.S. HEALTHCARE

313

Freenome

U.S. HEALTHCARE

79

Insilico Medicine

U.S. HEALTHCARE

8.26

Recursion Pharmaceuticals

U.S. HEALTHCARE

118.62

Tempus Labs

U.S. HEALTHCARE

70

Zymergen U.S. LIFE SCIENCE

174

ORIGINAL Source:

CB Insights; for the complete list, go to cbinsights.com/research-ai-100.

A version of this article appears in the Jan. 1, 2018 issue of Fortune with the headline “Leading the Way in A.I.”

Second SOURCE

http://fortune.com/2018/01/08/artificial-intelligence-ai-companies-invest-startups/

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Defining Health Care’s Future: Digital Health, Innovation Accessible, Prevention Importance as Cure – The Vision of Stanford Medical School Dean delivered at 2018 JP Morgan in San Francisco

Reporter: Aviva Lev-Ari, PhD, RN

 

At JPM 2018: Three Challenges That Will Define Health Care’s Future

Lloyd Minor

Lloyd Minor, LinkedIn Influencer

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PMC Comment Letter on Centers for Medicare & Medicaid Services: Innovation Center New Direction

Guest Author: Cynthia A. Bens, Vice President, Public Policy, PMC

cbens@personalizedmedicinecoalition.org

NOVEMBER 27, 2017

In response to a Wall Street Journal op-ed and request for information about innovative ways to pay for and deliver health care in the U.S., the Personalized Medicine Coalition has encouraged the Centers for Medicare & Medicaid Services (CMS) to spearhead models that empower physicians to move away from the current standard of care when patient outcomes can be improved by tailoring care to a patient’s genetics and other factors:

In keeping with PMC’s mission to underline the significance of personalized medicine to patients and the health system, the Coalition’s comment letter contends that personalized medicine products and services can increase the overall value of dollars spent by improving health outcomes.

CMS’ previous efforts to advance new payment models, the letter notes, were met with resistance largely because they focused on reducing overall health care costs without adequately considering whether those reductions would result in a disproportionate decrease in the outcomes that matter to patients.

PMC indicates in the letter that the guiding principles put forth in CMS’ request for information provide “reasonable assurance” that the agency plans to proceed at “a more measured pace” going forward.

“We believe that personalized medicine has the potential to help CMS deliver on its goal of [affordable, accessible health care] if [the agency] focuses on maximizing individual patient outcomes, if new models are fully evaluated before large-scale implementation, if payment is not rooted in current standard of care, and if physicians have the flexibility to tailor care based on a patient’s genetics and other factors,” the letter reads.

Please contact Cynthia A. Bens, Vice President, Public Policy, at cbens@personalizedmedicinecoalition.org with questions about PMC’s comment letter.

###

Personalized Medicine Coalition
1710 Rhode Island Ave. NW; Suite 700
Washington, D.C. 20036
Blog: Education & Advocacy
Twitter: @PerMedCoalition
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From: Personalized Medicine Coalition <messages@app.production.membersuite.com>
Reply-To: “Christopher Wells (PMC)” <cwells@personalizedmedicinecoalition.org>
Date: Monday, November 27, 2017 at 2:58 PM
To: Aviva Lev-Ari <AvivaLev-Ari@alum.berkeley.edu>
Subject: PMC to CMS: To Increase Value, Empower Physicians to Tailor Care, Optimize Outcomes

 and

From: “Christopher Wells (PMC)” <cwells@personalizedmedicinecoalition.org>

Date: Tuesday, November 28, 2017 at 7:34 AM

To: Aviva Lev-Ari <AvivaLev-Ari@alum.berkeley.edu>

Subject: Re: PMC to CMS: To Increase Value, Empower Physicians to Tailor Care, Optimize Outcomes

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The Future of Hospitals – How Medical Care and Technology Work Together to Advance Patient Care 

Curator: Gail S. Thornton, M.A.

Co-Editor: The VOICES of Patients, Hospital CEOs, HealthCare Providers, Caregivers and Families: Personal Experience with Critical Care and Invasive Medical Procedures

 

Gap Medics (https://www.gapmedics.com/blog/), the world’s leading provider of hospital work experience placements for high school and university students, recently released their “Futuristic Hospitals” infographic. The infographic reviews a collection of top hospitals in the world based on several key factors:

  • overall patient care,
  • innovative medical and technological excellence,
  • efforts toward sustainability,
  • environmental stewardship, and
  • social responsibility, as well as
  • other innovative health care features

to help advance the field of medicine and, ultimately, patient care.

Futuristic Hospitals Infographic

Image SOURCE: Infographic of Futuristic Hospitals courtesy of Evolved Digital and Gap Medics. Reprinted here with Permission from the Source.

 

“Many leading hospital facilities are now rolling out significant improvements and changes that couldn’t have been envisioned 10 years ago,” said Ian McIntosh, Director, Evolved Digital (http://evolveddigital.co.uk/), a U.K.-based digital marketing company specializing in search engine optimization and content marketing, whose team created the infographic for Gap Medics.

Science and innovation are working together to help convey higher expectations for quality medical and health care and advancements in the hospital experience for health care providers, patients and their families.

Particularly, the infographic analyzed prominent hospitals around the world so patients and their families can learn about the latest advances and efforts in patient care and hospital and medical technology.

In this infographic, we investigated the most cutting-edge hospital facilities in the world, where best-in-class technology and innovative medical care are making a difference in providing a quality experience all over the world.

“Gap Medics creates programs offered to thousands of students from Europe, Asia and the United States so they have the opportunity to gain insights into the work of doctors, nurses, physician assistants, midwives and dentists before the students begin their clinical training,” said Dave Brown, Director, Gap Medics, a U.K.-based company that provides hospital work experience between 1-8 weeks to students 16 years of age and older.

This one-in-a-lifetime opportunity helps students better understand their chosen career path, develop as people, and strengthen their university application process.

 

REFERENCE/SOURCE

http://evolveddigital.co.uk/

https://www.gapmedics.com/blog/2017/03/27/futuristic-hospitals/

Other related articles published in this Open Access Online Scientific Journal include the following:

 

“Sudden Cardiac Death,” SudD is in Ferrer inCode’s Suite of Cardiovascular Genetic Tests to be Commercialized in the US

Curator: Aviva Lev-Ari, PhD, RN

https://pharmaceuticalintelligence.com/2014/02/10/sudden-cardiac-death-sudd-is-in-ferrer-incodes-suite-of-cardiovascular-genetic-tests-to-be-commercialized-in-the-us/

 

Hybrid Cath Lab/OR Suite’s da Vinci Surgical Robot of Intuitive Surgical gets FDA Warning Letter on Robot Track Record

Reporter: Aviva Lev-Ari, PhD, RN

https://pharmaceuticalintelligence.com/2013/07/19/hybrid-cath-labor-suites-da-vinci-surgical-robot-of-intuitive-surgical-gets-fda-warning-letter-on-robot-track-record/

 

3D Cardiovascular Theater – Hybrid Cath Lab/OR Suite, Hybrid Surgery, Complications Post PCI and Repeat Sternotomy

Curator: Aviva Lev-Ari, PhD, RN

https://pharmaceuticalintelligence.com/2013/07/19/3d-cardiovascular-theater-hybrid-cath-labor-suite-hybrid-surgery-complications-post-pci-and-repeat-sternotomy/

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