Archive for the ‘Health Care System by Country’ Category

Reporter and Curator: Dr. Sudipta Saha, Ph.D.


Hepatitis B virus can cause serious, long-term health problems, such as liver disease and cancer, and can spread from mother-to-child during delivery. According to the latest estimates from the World Health Organization (WHO), approximately 257 million people in 2015 were living with the virus. Countries in Asia have a high burden of hepatitis B. There is no cure, and antiviral drugs used to treat the infection usually need to be taken for life.


To prevent infection, WHO recommends that all newborns receive their first dose of hepatitis B vaccine within 24 hours of delivery. Infants born to hepatitis B-infected mothers are also given protective antibodies called hepatitis B immune globulin (HBIG). However, mother-to-child transmission can still occur in women with high levels of virus in their blood, as well as those with mutated versions of the virus.


Tenofovir disoproxil fumarate (TDF), an antiviral drug commonly prescribed to treat hepatitis B infection, does not significantly reduce mother-to-child transmission of hepatitis B virus when taken during pregnancy and after delivery, according to a phase III clinical trial in Thailand funded by the National Institutes of Health. The study tested TDF therapy in addition to the standard preventative regimen — administration of hepatitis B vaccine and protective antibodies at birth — to explore the drug’s potential effects on mother-to-child transmission rates. The results appear in the New England Journal of Medicine.


The present study was conducted at 17 hospitals of the Ministry of Public Health in Thailand. It screened more than 2,500 women for eligibility and enrolled 331 pregnant women with hepatitis B. The women received placebo (163) or TDF (168) at intervals from 28 weeks of pregnancy to two months after delivery. All infants received standard hepatitis B preventatives given in Thailand, which include HBIG at birth and five doses of the hepatitis B vaccine by age 6 months (which differs from the three doses given in the United States). A total of 294 infants (147 in each group) were followed through age 6 months.


Three infants in the placebo group had hepatitis B infection at age 6 months, compared to zero infants in the TDF treatment group. Given the unexpectedly low transmission rate in the placebo group, the researchers concluded that the addition of TDF to current recommendations did not significantly reduce mother-to-child transmission of the virus.


According to the study, the clinical trial had enough participants to detect statistical differences if the transmission rate in the placebo group reached at least 12 percent, a rate observed in previous studies. Though the reasons are unknown, the researchers speculate that the lower transmission rate seen in the study may relate to the number of doses of hepatitis B vaccine given to infants in Thailand, lower rates of amniocentesis and Cesarean section deliveries in this study, or the lower prevalence of mutated viruses that result in higher vaccine efficacy in Thailand compared to other countries.





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2018 Annual World Medical Innovation Forum Artificial Intelligence April 23–25, 2018 Boston, Massachusetts  | Westin Copley Place


Aviva Lev-Ari, PhD, RN,

Founder and Director of LPBI Group will be in attendance covering the event in REAL TIME




All TWEETS from LPBI’s handles at #WMIF18





Panel Topics*

AI and Gene Sequencing
Can AI Based Drug Development Feed A Hungry Pipeline?
Driving Down the Cost of Trials with Real World and Real Time Evidence
Drug Therapy Redefined Through Machine Learning
Illuminating the Path to Physician Empowerment: Increasing Empowerment, Decreasing Burnout
Learning Computers in Healthcare: Challenges, Requirements and Opportunities
Machine Learning in Image Analysis: A Diagnostician’s Best Friend…or Replacement?
Paying for AI: Thinking Strategically About Reimbursements and Acceptance
Reconceiving Medical Device in an AI Dominated Environment
Reflecting on the Impact of AI in the Clinic and the Lab: Chairs Roundtable
Regulating AI in Healthcare, Requirements and Challenges
Smart EHRs: An Unsupervised Learning Problem
Tangible Returns on the AI Value Proposition
The AI Opportunity: A True Industry Inflection Point: CEO Roundtable
The Learning Provider: AI in Hospital Environments
Will AI Bend the Cost and Access Curve


*Under Development


2018 Speakers

Featured Speakers

Jensen Huang


Vasant Narasimhan MD

CMO and CEO-designate Novartis

Paul Ricci

CEO, Nuance

Atul Gawande MD

Executive Director, Ariadne Labs; Samuel O. Thier Professor of Surgery, Harvard Medical School; Surgeon, Brigham and Women’s Hospital

Sue Siegel

Chief Innovation Officer, GE

Frans van Houten

CEO, Philips

Bernd Montag PhD

CEO, Siemens Healthineers

John Kelly PhD

Senior Vice President, Cognitive Solutions and Research, IBM

Colin Hill

CEO, GNS Healthcare

Diana Nole

CEO, Wolters Kluwer Health

Fabien Beckers PhD

CEO, Arterys

Elad Benjamin

CEO, Zebra Medical Vision

Georgia Papathomas PhD

Global Head of Data Sciences, Johnson & Johnson

Dan Burton

CEO. Health Catalyst

Patrick Conway MD

President and CEO-Elect, Blue Cross and Blue Shield of North Carolina

Jackie Hunter, PhD

CEO, BenevolentAI

Noga Leviner

CEO, Picnic Health

Leonard D’Avolio, PhD

CEO, Cyft, Inc.

Iain Buchan MD

‎Director of Healthcare Research, Microsoft Research

Andrew Hopkins

CEO, Exscientia

Gabriel Otte

CEO, Freenome

David Torchiana MD,

CEO, Partners HealthCare

Susan Tousi

Senior Vice President, Product Development, Illumina, Inc.

Tim Tuttle

CTO, Cognitive Collaboration Group, Cisco


Note: speakers are subject to change.



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HealthCare focused AI Startups from the 100 Companies Leading the Way in A.I. Globally

Reporter: Aviva Lev-Ari, PhD, RN


These 100 Companies Are Leading the Way in A.I.

By Nicolas Rapp and Brian O’Keefe

January 8, 2018

Whether you fear it or embrace it, the A.I. revolution is coming—and it promises to have an enormous impact on the world economy. PwC estimates that artificial intelligence could add $15.7 trillion to global GDP by 2030. That’s a gargantuan opportunity. To identify which private companies are set to make the most of it, research firm CB Insights recently released its 2018 “A.I. 100,” a list of the most promising A.I. startups globally (grouped by sector in the graphic above). They were chosen, from a pool of over 1,000 candidates, by CB Insights’ Mosaic algorithm, based on factors like investor quality and momentum.

  • China’s Bytedance leads in funding with $3.1 billion, but
  • 76 of the 100 startups are U.S.-based.



  • A Focus on Health Care and Life Sciences Sectors show that of 100 AI start ups, only 9 are in Health Care that made the cut from the initial 1,000 start ups considered for inclusion in the classification by Sector done by CB Insights, using CB Insights’ Mosaic algorithm
  • Three US Based AI start ups in Health Care have already funding exceeding $100 Million:
  1. Flatiron Health – $313 Million
  2. Recursion Pharmaceuticals – $118.62 Million
  3. Zymergen – $174 Million
  • That list does not include Health Care related AI investments in Non start ups.
  • In the US, Non start ups Health Care related AI investments include the following:

Veterans Health Administration – Veterans Affairs


Health Care HMOs:

Kaiser Permanenete, Partners

Health Care Insurance Companies:

United HealthCare, Blue Cross Blue Shield

Academic Hospitals:

MGH, Duke Medical Center, Stanford Medical Center,

2018 Annual World Medical Innovation Forum

Artificial Intelligence

April 23–25, 2018
Boston, Massachusetts  |  Westin Copley Place
For inquiries:

The World Medical Innovation Forum is a global gathering of more than 1,000 senior health care leaders in the heart of Boston. It was established to respond to the intensifying transformation of health care and its impact on innovation. The Forum is rooted in the belief that no matter the magnitude of that change, the center of health care needs to be a shared, fundamental commitment to collaborative innovation – industry and academia working together to improve patient lives.

APRIL 23–25, 2018




($ Mil.)










Flatiron Health






Insilico Medicine



Recursion Pharmaceuticals



Tempus Labs






CB Insights; for the complete list, go to

A version of this article appears in the Jan. 1, 2018 issue of Fortune with the headline “Leading the Way in A.I.”


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Defining Health Care’s Future: Digital Health, Innovation Accessible, Prevention Importance as Cure – The Vision of Stanford Medical School Dean delivered at 2018 JP Morgan in San Francisco

Reporter: Aviva Lev-Ari, PhD, RN


At JPM 2018: Three Challenges That Will Define Health Care’s Future

Lloyd Minor

Lloyd Minor, LinkedIn Influencer

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PMC Comment Letter on Centers for Medicare & Medicaid Services: Innovation Center New Direction

Guest Author: Cynthia A. Bens, Vice President, Public Policy, PMC

NOVEMBER 27, 2017

In response to a Wall Street Journal op-ed and request for information about innovative ways to pay for and deliver health care in the U.S., the Personalized Medicine Coalition has encouraged the Centers for Medicare & Medicaid Services (CMS) to spearhead models that empower physicians to move away from the current standard of care when patient outcomes can be improved by tailoring care to a patient’s genetics and other factors:

In keeping with PMC’s mission to underline the significance of personalized medicine to patients and the health system, the Coalition’s comment letter contends that personalized medicine products and services can increase the overall value of dollars spent by improving health outcomes.

CMS’ previous efforts to advance new payment models, the letter notes, were met with resistance largely because they focused on reducing overall health care costs without adequately considering whether those reductions would result in a disproportionate decrease in the outcomes that matter to patients.

PMC indicates in the letter that the guiding principles put forth in CMS’ request for information provide “reasonable assurance” that the agency plans to proceed at “a more measured pace” going forward.

“We believe that personalized medicine has the potential to help CMS deliver on its goal of [affordable, accessible health care] if [the agency] focuses on maximizing individual patient outcomes, if new models are fully evaluated before large-scale implementation, if payment is not rooted in current standard of care, and if physicians have the flexibility to tailor care based on a patient’s genetics and other factors,” the letter reads.

Please contact Cynthia A. Bens, Vice President, Public Policy, at with questions about PMC’s comment letter.


Personalized Medicine Coalition
1710 Rhode Island Ave. NW; Suite 700
Washington, D.C. 20036
Blog: Education & Advocacy
Twitter: @PerMedCoalition


From: Personalized Medicine Coalition <>
Reply-To: “Christopher Wells (PMC)” <>
Date: Monday, November 27, 2017 at 2:58 PM
To: Aviva Lev-Ari <>
Subject: PMC to CMS: To Increase Value, Empower Physicians to Tailor Care, Optimize Outcomes


From: “Christopher Wells (PMC)” <>

Date: Tuesday, November 28, 2017 at 7:34 AM

To: Aviva Lev-Ari <>

Subject: Re: PMC to CMS: To Increase Value, Empower Physicians to Tailor Care, Optimize Outcomes

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The Future of Hospitals – How Medical Care and Technology Work Together to Advance Patient Care 

Curator: Gail S. Thornton, M.A.

Co-Editor: The VOICES of Patients, Hospital CEOs, HealthCare Providers, Caregivers and Families: Personal Experience with Critical Care and Invasive Medical Procedures


Gap Medics (, the world’s leading provider of hospital work experience placements for high school and university students, recently released their “Futuristic Hospitals” infographic. The infographic reviews a collection of top hospitals in the world based on several key factors:

  • overall patient care,
  • innovative medical and technological excellence,
  • efforts toward sustainability,
  • environmental stewardship, and
  • social responsibility, as well as
  • other innovative health care features

to help advance the field of medicine and, ultimately, patient care.

Futuristic Hospitals Infographic

Image SOURCE: Infographic of Futuristic Hospitals courtesy of Evolved Digital and Gap Medics. Reprinted here with Permission from the Source.


“Many leading hospital facilities are now rolling out significant improvements and changes that couldn’t have been envisioned 10 years ago,” said Ian McIntosh, Director, Evolved Digital (, a U.K.-based digital marketing company specializing in search engine optimization and content marketing, whose team created the infographic for Gap Medics.

Science and innovation are working together to help convey higher expectations for quality medical and health care and advancements in the hospital experience for health care providers, patients and their families.

Particularly, the infographic analyzed prominent hospitals around the world so patients and their families can learn about the latest advances and efforts in patient care and hospital and medical technology.

In this infographic, we investigated the most cutting-edge hospital facilities in the world, where best-in-class technology and innovative medical care are making a difference in providing a quality experience all over the world.

“Gap Medics creates programs offered to thousands of students from Europe, Asia and the United States so they have the opportunity to gain insights into the work of doctors, nurses, physician assistants, midwives and dentists before the students begin their clinical training,” said Dave Brown, Director, Gap Medics, a U.K.-based company that provides hospital work experience between 1-8 weeks to students 16 years of age and older.

This one-in-a-lifetime opportunity helps students better understand their chosen career path, develop as people, and strengthen their university application process.



Other related articles published in this Open Access Online Scientific Journal include the following:


“Sudden Cardiac Death,” SudD is in Ferrer inCode’s Suite of Cardiovascular Genetic Tests to be Commercialized in the US

Curator: Aviva Lev-Ari, PhD, RN


Hybrid Cath Lab/OR Suite’s da Vinci Surgical Robot of Intuitive Surgical gets FDA Warning Letter on Robot Track Record

Reporter: Aviva Lev-Ari, PhD, RN


3D Cardiovascular Theater – Hybrid Cath Lab/OR Suite, Hybrid Surgery, Complications Post PCI and Repeat Sternotomy

Curator: Aviva Lev-Ari, PhD, RN

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The Lancet : Health in Israel – One Historic Issue to Review

Reporter: Aviva Lev-Ari, PhD, RN



Health in Israel

Published: May 8, 2017

Executive Summary

These five Lancet Series papers and accompanying comments outline Israel’s achievements in health and health care, towards a goal of attaining universal health coverage for an unusually diverse population. The papers explore Israel’s unique history, challenges, and accomplishments, and the religious and regional influences that have had an impact on health. The Series also offers an insight into existing collaborations and potential future opportunities, and outlines extensive recommendations to address the persisting inequalities between population groups, and to further strengthen health-care delivery systems.




  • A personal perspective on health in Israel

    Tamara Lucas
    The Lancet
    Published: May 8, 2017
  • Digital health nation: Israel’s global big data innovation hub

    Ran D Balicer, Arnon Afek
    The Lancet
    Published: May 8, 2017
  • Medical genetics in Israel’s diverse population

    Satvit A Shalev, Joel Zlotogora, Adel Shalata, Ephrat Levy-Lahad
    The Lancet
    Published: May 8, 2017


  • Rafael Beyar: a meeting of medicine, science, and technology

    Tamara Lucas
    The Lancet
    Published: May 8, 2017
  • Orly Manor: public health leader in Israel’s health system

    Richard Lane
    The Lancet
    Published: May 8, 2017


  • Health and health care in Israel: an introduction

    A Mark Clarfield, Orly Manor, Gabi Bin Nun, Shifra Shvarts, Zaher S Azzam, Arnon Afek, Fuad Basis, Avi Israeli
    The Lancet
    Published: May 8, 2017
  • Maternal and child health in Israel: building lives

    Lisa Rubin, Ilana Belmaker, Eli Somekh, Jacob Urkin, Mary Rudolf, Mira Honovich, Natalya Bilenko, Zachi Grossman
    The Lancet
    Published: May 8, 2017
  • Inequalities in non-communicable diseases between the major population groups in Israel: achievements and challenges

    Khitam Muhsen, Manfred S Green, Varda Soskolne, Yehuda Neumark
    The Lancet
    Published: May 8, 2017
  • Coming of age: health-care challenges of an ageing population in Israel

    Tzvi Dwolatzky, Jenny Brodsky, Faisal Azaiza, A Mark Clarfield, Jeremy M Jacobs, Howard Litwin
    The Lancet
    Published: May 8, 2017
  • Israel: health and beyond

    Karl Skorecki, Richard Horton
    The Lancet
    Published: May 8, 2017


  • Israel: a start-up life science nation

    Rafael Beyar, Benny Zeevi, Gideon Rechavi
    The Lancet
    Published: May 8, 2017
  • The medical education system in Israel

    Shmuel Reis, Shimon M Glick, Jacob Urkin, Peter Gilbey
    The Lancet
    Published: May 8, 2017
  • Women and health in Israel

    Leeat Granek, Ora Nakash, Rivka Carmi
    The Lancet
    Published: May 8, 2017
  • Helping hands across a war-torn border: the Israeli medical effort treating casualties of the Syrian Civil War

    Hany Bahouth, Amir Shlaifer, Avraham Yitzhak, Elon Glassberg
    The Lancet
    Published: May 8, 2017


  • Medical ethics in Israel—bridging religious and secular values

    Alan B Jotkowitz, Riad Agbaria, Shimon M Glick
    The Lancet
    Published: May 8, 2017


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