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Real Time Conference Coverage : 2026 Mid-Atlantic Capital Conference; November 10, 2026 Philadelphia PA

Reporter: Stephen J. Williams, Ph.D.

 

 

Mid-Atlantic Capital Conference

November 9 & 10, 2026

Philadelphia, PA | Presented by PACT

“Cap Con” is one of the largest venture capital conferences on the East Coast — a dynamic platform where innovation meets investment. For over 30 years, the conference has connected emerging growth companies, investors, advisors, and corporate leaders from across the region.

The conference culminates in the Lion’s Den — our version of Shark Tank — where real dollars are invested and real deals are made in front of the room.

Agenda

Tuesday, November 10th 2026

2026 Mid-Atlantic Capital Conference – Pennsylvania Convention Center – 1101 Arch St. Philadelphia, PA 19107

Corporate Innovation Panel Track

10:20 AM – 11:00 AM

201 ABC

Navigating the AI Future: Where Will Value Be Created and Destroyed?

Envision potential future AI scenarios and their implication over the next 3-5 years. 
 
It’s a whole new world. AI is reshaping not only what companies build, but what a company can look like. This interactive session will challenge attendees to explore three possible AI Future Scenarios covering shifts in technology, economics, regulation, and societal response to AI as well as the implications for future enterprises from established companies transforming with AI to AI-natives companies disrupting existing markets with a fraction of the employees.

Through scenario discussions and audience polling, investors, founders, and corporate leaders will consider where durable value will exist, what will remain uniquely human, and how these shifts should change the way we invest and innovate. 

10:20 AM

204 A

Featured Company Presentations Round 1

Healthcare & Life Sciences

  • SynchNeuro
  • Carenostics
  • Moberg Analytics, Inc.
  • Polygon Health Analytics LLC
  • Mind and Match

10:20 AM

204 B

Featured Company Presentations Round 1

Growth Stage

  • DermaSensor Inc.
  • Endomedix, Inc.
  • Meduloc
  • BLUEWAVE Technologies
  • Chromatan Inc

10:20 AM

204 C

Featured Company Presentations Round 1

Technology

  • Raptor Defense Company
  • Serpent Robotics
  • BleedIo, Tech
  • TechNovaTime
  • Alive3D

11:15 AM – 11:55 AM

201 ABC

Beyond the Pilot: Building AI That Actually Delivers 

As organizations gain a clearer understanding of AI’s potential, the focus is shifting toward how these technologies can be thoughtfully adopted and applied to create measurable business value. This session will explore what it takes to move AI, agents, and agentic systems from experimentation into production, where organizations are seeing real ROI, and how leaders can distinguish transformative applications from expensive experimentation.

  • how can AI be made relevant at scale?  How do we move from the pilot AI to a scaled up AI solution
  • CGI moderates the panel of Jefferson Health, Haleon, and TransAmerica
  • Abhijit Singh:  people were not trusting the new technology; the biggest takeaway he had after initiating pilots was that reengineering the solution was an issue because they had to do AI audits but it tooks time to see which pilots failed, especially in health care; Abhijit agrees with Dean on the pain points that it is even more crucial in healthcare; what is problem trying to solve as experts are needed, a general agentic would not be good enough to give value to healthcare industry;  Mark from Haleon agrees with this synopsis
  • Mark Manning: Consumer healthcare company; they had lots of pilot projects started; they experimented with multiple ideas but had issues with measuring success; the AI platform only good as what it has access to;  AI was not giving the depth of answers; they need more relevant agentic AI;  he calls the results ‘shallow’
  • Dean Holland: TransAmerica decided to make their own platform which they call Agentic and seen an acceleration by building their own platform than using an LLM from others like OpenAI; at first they have been having problems with the outcomes; they see an issue with a need for DOMAIN EXPERTISE, it appears to be a pain point in the industry
  • Question: how are you changing operations in digital teams to produce most value?  Mark says their teams are now focused on specific goals so they remain focused on outcomes.  How are they partnering with the hyperscalers? Abjihit: There are lots of decision makers in a hospital so multiple teams evaluate adopting any solutions from partners or hyperscalers: for example radiology imaging has acute shortage of radiologists so can they leverage AI to improve radiology workflows;
  • Question: What comes next and what have you learned from pilots?: Mark; agentic commerce (who do they talk to), should they partner with people or companies; Dean: we are going back to beginning and starting to put projects on hold, they are revisiting their AI strategy (customer engagement and operations will be main focus) and they are needing that deep domain expertise; Jefferson is mainly focused on workflow optimization, however they do see potential to increase physicians interaction time with patients; Jefferson believes in changing entire workflow not just piecemeal solutions to individual problems or time-consuming tasks
  • TransAmerica wants to work closer with the Anthropics and OpenAI but it is imperative to work with internal teams
  • question from audience on partnering: Abhijit says AI is actually making partnering harder; Mark agrees that it takes months for internal teams approval to establish a partnership

11:15 AM

204 A

Featured Company Presentations Round 2

Healthcare & Life Sciences

  • Little One Nutrition Co
  • Nospharma
  • Prolifagen, Inc.
  • BioCurie
  • CTIBIOTECH USA

11:15 AM

204 B

Featured Company Presentations Round 2

Growth Stage

  • Mussel Polymers Inc
  • Setex Technologies
  • Antithesis Foods
  • BioFluff Inc
  • Persevere Therapeutics

11:15 AM

204 C

Featured Company Presentations Round 2

Technology

  • Phyll
  • Seedless
  • Syntropiq Inc.
  • GreenIRR Inc.
  • Value Unlimited Inc DBA OnPoint

12:30 PM

Ballroom A/B

Keynote Fireside Chat: Building a Championship Culture with Jay Wright

What does it take to build a winning team and sustain success over time? Join legendary Villanova men’s basketball coach and Naismith Memorial Basketball Hall of Fame inductee Jay Wright for a fireside chat with Stephanie Humphrey on leadership, teamwork, and building a culture of excellence.
Drawing from more than two decades leading Villanova, two NCAA national championships, and four Final Four appearances, Wright will share lessons on developing talent, fostering trust, navigating challenges, and creating an environment where individuals and teams can perform at their best. The conversation will explore how the principles behind championship teams can be applied to business, entrepreneurship, and organizational leadership.

1:30 PM – 2:10 PM

201 ABC

Startup × Investor × Corporate: Reinventing the Innovation Model 

The traditional playbook for corporate innovation is changing. As AI accelerates ideation, experimentation, lowers barriers to entry, and shortens the time between idea and market, startups, investors, and enterprises are rethinking how they build, buy, partner, and invest. Through real-world examples, this panel will explore how each player can work together to bring innovation to market faster—and what successful partnerships look like in the AI era. 

This presentation features a panel with:

Harris Kaplan, Litmys, LLC

Amanda McBride Wilk, Accenture

Ridhard Friedman,Noom

Moderator: Mikchael Bachman, Boomi

What is one thing AI has made less valuable this year?

  • Amanda: less impressive is flashy demo; need a concrete outputs; domain Knowledge is becoming more and more important;  Accenture has the ability to look at large clients data;  organizations are not sure where to go with the new technology; most of their successful deals are partnerships; humans are needed for judgement in investment decisions; AI is great at parsing large amounts of information; experts are still needed for judgement calls; AI does not have the experience
  • Richard: outputs may not be as valuable as the process; why are you doing something is not as important for a builder agentic systems;  he says they tested the small models by putting in the LLMs and LLMs are working better for them; context is important; curious why they are stilling feeding LLMs with SLMs
  • Harris: more valuable faster time to trial; less valuable is increasing using output of AI to do corporate strategy; he talks first hand to physicians and payer and now AI is focusing on the what but lost is the why (like how we change behavior); strategies do not change just the speed at which they can be executed; AI allows companies to assess what is going on quickly and pivot; VC firms need to pivot; AI can be the tool to allow for quick pivot in implementation of strategy
  • moderator: there will be changes in focus of AI in 2027-28; he has been hearing a lot about outcome based pricing; people are wondering how do you value to metric you are using to make the outcome based pricing; with deal making, Accenture would rather partner than invest and create value of the startup; Noom always looks at the platform and how platform increases value; Most of panel thinks there will be a lot less IPOs in 2027 except in niche areas

1:50 PM

204 A

Featured Company Presentations Round 3

Healthcare & Life Sciences

  • Dialysis-X, Inc.
  • Earable Intelligence
  • TOPAS Solutions, Inc.
  • Vivifi Medical Inc
  • Ozie

1:50 PM

204 B

Featured Company Presentations Round 3

Growth Stage

  • Burro
  • Raise Robotics, Inc.
  • Deepwave
  • Tiami Networks Inc
  • Transcendap

1:50 PM

204 C

Featured Company Presentations Round 3

Technology

  • BOSS Controls Inc
  • BUCKSTOP
  • CoStream Technologies, Inc.
  • Dunya Analytics
  • NanoSepex

2:30 PM – 3:00 PM

201 ABC

Building Advantage in the AI Era with Philip Moyer: Where Will the Next Generation of Value Be Created?

As AI becomes embedded across industries, access to powerful models alone won’t create a lasting competitive advantage. The next wave of opportunity will come from what companies build around them—the proprietary data, industry context, tools, workflows, and feedback loops that turn AI capabilities into differentiated products and measurable value.

In this fireside conversation, Philip Moyer of McGraw Hill will explore where value is being created across the emerging AI stack and what that means for startups, investors, and established companies. Drawing from his experience across the technology industry and now leading within a legacy organization undergoing its own transformation, Moyer will discuss how companies can identify opportunities for differentiation, build stronger data and context with every interaction, and create advantages that become more valuable over time.

The conversation will also examine what young companies should be building today, how established organizations can modernize their operating models, and where the next generation of enduring AI businesses may emerge as the technology continues to evolve.

Moderator: Frederic Miskawi

Where is the next value coming from?

Philip Moyer:

  • started out at Microsoft in this Philadelphia area. The last mile of any technology is the hardest part. At Mcgraw Hill he has been over the educational spectrum listening to customers (grade school, high school. medical school)  The era of Large models will end.  In his day AOL was the big player but it all will end.  They are encoding all these learning objectives during education (about 30,000 into ontologies).  LLMs don’t have the contextual ontology (memory).
  • Mcgraw Hill has over 1 million curriculums they serve…  They want universities to use agentic models as they will help protect copyrights.
  • most of the clouds like AWS built on open source and
  • digital moat: 1. speed to market 2.  trust (through partnerships) 3. context (move at speed)
  • McGraw Hill most is built on trust. Education market is 7 trillion market… higher than IT market
  • disruption only happens when you respect the industry.. respect teachers
  • show the data and outcomes to everyone (all stakeholders)
  • pace is also a moat for them: getting the pace of rollout of innovation is important
  • AI moves from answering questions to making goals.  AI can’t make goals now so it is important for human integration to make the goals and let agentic perform the workflows

3:05 PM – 3:45 PM

Ballroom – A/B

Reverse Pitch Live: Corporate Innovation Challenges 

The tables turn as corporate leaders take the stage to pitch their biggest business and technology challenges to the room. Instead of hearing what startups want to sell, founders and investors will hear directly from enterprises about the problems they are actively trying to solve, where they are looking for innovation, and what they need from potential partners. 

The session creates a live marketplace for collaboration: giving startups insight into real enterprise demand; investors visibility into emerging opportunities; and corporations access to new ideas and potential solutions. 

4:00 PM – 5:15 PM

201 ABC

Lion’s Den

The conference culminates in the Lion’s Den — our version of Shark Tank — where real dollars are invested and real deals are made in front of the room. Watch innovation meet opportunity as the most impressive start-ups from the day take the stage to pitch their businesses before a panel of investors. 

Each company will share how much capital it is seeking and the equity it is offering in return, while investors ask tough questions, evaluate the opportunity, and determine whether to make an investment. More than a competition, Lion’s Den offers an unfiltered look at what it takes to secure investment. Expect bold ideas, candid feedback, and an exciting glimpse into the future of healthcare, technology, and innovation.

Meeting Synopsis

This importance conference brought together three groups of stakeholders in corporate AI adoption: AI engineers, AI corporate strategists and consultants, and investors in AI.  There were multiple insights in discussions with these three groups including the long time it takes for any one entity, be it a hospital or a healthcare company, to adopt AI strategy into their workflows.  It was apparent that AI is generally being adopted to decrease workflow time and increase efficiency rather than use in discovery.  For instance, Jefferson Health mentioned they have to go through teams of physicians and healthcare workers along with IT people to see if any agentic AI can be integrated into their workflows, like radiology.  This takes months of strategy  meetings before a partnership or deal is made.  I did find it interesting that a beta test among patients is not included.  Another theme with the investors and consulting firms was they would rather do partnerships and pay for that instead of one off deals.  They had mentioned that there will be a dearth of IPOs in the next year 2027.  Many of the panelists mentioned it is easy  to make agents but the real question is WHY instead of what function does it serve.  They were careful of AI costs as well and some eluded to a sort of Blockchain system to contain AI costs.  Finally some had mentioned about the last mile for the technology will be the hardest phase for AI.  They had mentioned that although these large systems had been built out there is a severe lack of context which only experts in a field can offer.  The consulting firms are actively recruiting such experts with domain Knowledge as well as the engineers see this as a pain point in their organizations (the lack of domain expertise).

Tweet Collection

<blockquote class=”twitter-tweet”><p lang=”en” dir=”ltr”>Live coverage from Mid-Atlantic Capital Conference: @MHEducation New CEO Philip Moyer. We are developing multiple agentic #AI to assist teachers on classrooms; a $7 trillion market @PhilaPACT @Pharma_BI @AVIVA1950</p>&mdash; Stephen J Williams (@StephenJWillia2) <a href=”https://x.com/StephenJWillia2/status/2120268273526640931?ref_src=twsrc%5Etfw”>November 10, 2026</a></blockquote> <script async src=”https://platform.x.com/widgets.js&#8221; charset=”utf-8″></script>
Stephen J Williams
@StephenJWillia2
Live coverage from Mid-Atlantic Capital Conference:

New CEO Philip Moyer. We are developing multiple agentic #AI to assist teachers on classrooms; a $7 trillion market

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AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class III: 100 e-Proceedings and 50 Tweet Collections of Top Biotech and Medical Global Conferences, 2013-2025

Curator: Aviva Lev-Ari, PhD, RN

We had researched the topic of AI Initiatives in Big Pharma in the following article:

  • Authentic Relevance of LPBI Group’s Portfolio of IP as Proprietary Training Data Corpus for AI Initiatives at Big Pharma

https://pharmaceuticalintelligence.com/2025/11/15/authentic-relevance-of-lpbi-groups-portfolio-of-ip-as-proprietary-training-data-corpus-for-ai-initiatives-at-big-pharma/

 

We are publishing a Series of Five articles that demonstrate the Authentic Relevance of Five of the Ten Digital IP Asset Classes in LPBI Group’s Portfolio of IP for AI Initiatives at Big Pharma.

  • For the Ten IP Asset Classes in LPBI Group’s Portfolio, See

https://pharmaceuticalintelligence.com/portfolio-of-ip-assets/

The following Five Digital IP Asset classes are positioned as Proprietary Training Data and Inference for Foundation Models in Health care.
This Corpus comprises of Live Repository of Domain Knowledge Expert-Written Clinical Interpretations of Scientific Findings codified in the following five Digital IP ASSETS CLASSES:
• IP Asset Class I: Journal: PharmaceuticalIntelligence.com
6,250 scientific articles (70% curations, creative expert opinions.  30% scientific reports).
2.4MM Views, equivalent of $50MM if downloading an article is paid market rate of $30.

https://pharmaceuticalintelligence.com/vision/pharmaceuticalintelligence-com-journal-projecting-the-annual-rate-of-article-views/

 

• IP Asset Class II: 48 e-Books: English Edition & Spanish Edition.
152,000 pages downloaded under pay-per-view. The largest number of downloads for one e-Publisher (LPBI)
• IP Asset Class III: 100 e-Proceedings and 50 Tweet Collections of Top Biotech and Medical Global Conferences, 2013-2025
Article Summary by @Grok
Conclusions and Implications
LPBI Group’s IP Asset Class III assets are “rare, defensible” for Big Pharma AI, powering from R&D acceleration to equitable care. Technical Implications: Enables theme-specific models (e.g., oncology conferences) for diagnostics/trials. Business Implications: Boosts ROI on $500M investments; licensing for symposia/webinars. Unique Insight: As the sole record of speaker insights, these outpace public data for “frontier” inference—key in series for holistic pharma AI moats.Promotional with resource links (e.g., IP portfolio, biotech conference lists). Complements prior pieces by adding temporal/event depth.

• IP Asset Class V: 7,500 Biological Images in our Digital Art Media Gallery, as prior art. The Media Gallery resides in WordPress.com Cloud of LPBI Group’s Web site

• IP Asset Class X: +300 Audio Podcasts: Interviews with Scientific Leaders
BECAUSE THE ABOVE ASSETS ARE DIGITAL ASSETS they are ready for use as Proprietary TRAINING DATA and INFERENCE for AI Foundation Models in HealthCare.
Expert‑curated healthcare corpus mapped to a living ontology, already packaged for immediate model ingestion and suitable for safe pre-training, evals, fine‑tuning and inference. If healthcare domain data is on your roadmap, this is a rare, defensible asset.
The article TITLE of each of the five Digital IP Asset Classes matched to AI Initiatives in Big Pharma, an article per IP Asset Class are:
  • AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class I: PharmaceuticalIntelligence.com Journal, 2.5MM Views, 6,250 Scientific articles and Live Ontology

https://pharmaceuticalintelligence.com/2025/11/22/ai-initiatives-in-big-pharma-grog-prompt-proprietary-data-training-and-inference-by-lpbi-groups-ip-asset-class-i-pharmaceuticalintelligence-com-journal-2-5mm-views-6250-scientific-article/

 

  • AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class II: 48 e-Books: English Edition & Spanish Edition. 152,000 pages downloaded under pay-per-view

https://pharmaceuticalintelligence.com/2025/11/22/ai-initiatives-in-big-pharma-grog-prompt-proprietary-training-data-and-inference-by-lpbi-groups-ip-asset-class-ii-48-e-books-english-edition-spanish-edition-152000/

 

  • AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class III: 100 e-Proceedings and 50 Tweet Collections of Top Biotech and Medical Global Conferences, 2013-2025

https://pharmaceuticalintelligence.com/2025/11/22/ai-initiatives-in-big-pharma-grog-prompt-proprietary-training-data-and-inference-by-lpbi-groups-ip-asset-class-iii-100-e-proceedings-and-50-tweet-collections-of-top-biotech/

 

  • AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class V: 7,500 Biological Images in LPBI Group’s Digital Art Media Gallery, as Prior Art

https://pharmaceuticalintelligence.com/2025/11/22/ai-initiatives-in-big-pharma-grog-prompt-proprietary-training-data-and-inference-by-lpbi-groups-ip-asset-class-v-7500-biological-images-in-lpbi-groups-digital-art/

 

  • AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class X: +300 Audio Podcasts Library: Interviews with Scientific Leaders

https://pharmaceuticalintelligence.com/2025/11/22/ai-initiatives-in-big-pharma-grog-prompt-proprietary-training-data-and-inference-by-lpbi-groups-ip-asset-class-x-300-audio-podcasts-library-interviews-with-scientific-leaders/

 

In the series of five articles, as above, we are presenting the key AI Initiatives in Big Pharma as it was created by our prompt to @Grok on 11/18/2025:

  • What are PFIZER’s AI INITIATIVES?

@Grok Response:

x.com/i/grok/share/0ol5VOJsEYs11baXq4xkzNb0h

Generative AI tools that save scientists up to 16,000 hours annually in literature searches and data analysis.
Drug Discovery and Development Acceleration Pfizer uses AI, supercomputing, and ML to streamline R&D timelines
Clinical Trials and Regulatory Efficiency AI:

-Predictive Regulatory Tools

-Decentralize Trials

-inventory management

Disease Detection and Diagnostics:

–       ATTR-CM Initiative

–       Rare diseases

Generative AI and Operational Tools:

–       Charlie Platform

–       Scientific Data Cloud AWS powered ML on centralized data

–       Amazon’s SageMaker /Bedrock for Manufacturing efficiency

–       Global Health Grants:

Pfizer Foundation’s AI Learning Lab for equitable access to care and tools for community care

Partnerships and Education

–       Collaborations: IMI Big Picture for 3M – sample disease database

–       AI in Pharma AIPM Symposium: Drug discovery and Precision Medicine

–       Webinars of AI for biomedical data integration

–       Webinar on AI in Manufacturing

Strategic Focus:

–       $500M R&D reinvestment by 2026 targets AI for Productivity

–       Part of $7.7B cost savings

–       Ethical AI, diverse DBs

–       Global biotech advances: China’s AI in CRISPR

  • AI Initiatives in Big Pharma @Grok prompt &amp; Proprietary Training Data and Inference by LPBI Group’s IP Asset Class III: 100 e-Proceedings and 50 Tweet Collections of Top Biotech and Medical Global Conferences, 2013-2025

The Left Column was written @Grok

The Right Column was written by Aviva Lev-Ari, PhD, RN

 

AI Initiative at Big Pharma

i.e., Pfizer

e-Proceedings: N = +100

and

Tweet Collections: N = +50

Generative AI tools that save scientists up to 16,000 hours annually in literature searches and data analysis.
Drug Discovery and Development Acceleration Pfizer uses AI, supercomputing, and ML to streamline R&D timelines e-Proceeding of +100 TOP Conferences in Biotech, in Medicine, in Genomics, in Precision Medicine

https://pharmaceuticalintelligence.com/press-coverage/part-two-list-of-biotech-conferences-2013-to-present/

In these conferences the Frontier of Science was presented. These Proceedings are the ONLY written record of the events.

The tweet Collection are QUOTES of speakers on record. NOT ELSEWHERE available by name of speaker and affiliation

Clinical Trials and Regulatory Efficiency AI:

-Predictive Regulatory Tools

-Decentralize Trials

-inventory management

Disease Detection and Diagnostics:

–       ATTR-CM Initiative

–       Rare diseases

Generative AI and Operational Tools:

–       Charlie Platform

–       Scientific Data Cloud AWS powered ML on centralized data

–       Amazon’s SageMaker/Bedrock for Manufacturing efficiency

–       Global Health Grants:

Pfizer Foundation’s AI Learning Lab for equitable  access to care and tools for community care

Ingest to Charlie Platform ALL e-Proceedings of ALL Conferences

 

Apply GPT:

Training Data:

–       One conference at a time

–       All Conference on ONE subject matter, i.e., Immunotherapy, Oncolytic Virus Immunotherapy, Immune Oncology

Partnerships and Education

–       Collaborations: IMI Big Picture for 3M – sample disease database

–       AI in Pharma AIPM Symposium: Drug discovery and Precision Medicine

–       Webinars of AI for biomedical data integration

–       Webinar on Ai in Manufacturing

Use Past agendas to build Future Conference Agendas

Use Speakers Lists

Use topics covered in Employee training & and in Leadership development

Strategic Focus:

–       $500M R&D reinvestment by 2026 targets AI for Productivity

–       Part of $7.7B cost savings

–       Ethical AI, diverse DBs

–       Global biotech advances: China’s AI in CRISPR

Having access to +100 e-Proceedings vs Not having access to this resource is a make or break in Branding

 

CONCLUSIONS: The Voice of Dr. Stephen J. Williams PhD

PENDING

Article Summary of the ArticleTitle:

AI Initiatives in Big Pharma @Grok prompt & Proprietary Training Data and Inference by LPBI Group’s IP Asset Class III: 100 e-Proceedings and 50 Tweet Collections of Top Biotech and Medical Global Conferences, 2013-2025

Publication Date: November 22, 2025

Author/Curator: Aviva Lev-Ari, PhD, RN
(Curator; Posted by 2012pharmaceutical)
@Grok SOURCE:


Overview: Third in LPBI Group’s five-article series on AI-ready digital IP assets for Pharma companies. This installment highlights IP Asset Class III—100 e-proceedings and 50 tweet collections from top global biotech/medical conferences (2013-2025)—as a proprietary, expert-curated corpus of frontier science insights. Using a November 18, 2025, Grok prompt on Pfizer’s AI efforts, it maps these assets to pharma applications, stressing their role in training/inference for foundation models. Unlike prior classes (journal articles, e-books), this focuses on real-time event captures (e.g., speaker quotes, agendas) as unique, non-replicable data for efficiency, education, and branding in AI-driven R&D.

Main Thesis and Key Arguments

  • Core Idea: LPBI’s IP Asset Class III assets provide the “only written record” of +100 top conferences, with tweet collections as verbatim speaker quotes/affiliations—ideal for ingesting into AI platforms to amplify human expertise in combinatorial predictions. This supports Pfizer’s goals like 16,000-hour savings via generative AI, enabling subject-specific training (e.g., immunotherapy) and future agenda building.
  • Value Proposition: 150 total assets (100 e-proceedings + 50 tweet collections) form a live repository of domain knowledge, mapped to ontology for immediate AI use. Equivalent to $50MM value (aligned with series benchmarks); unique for branding (“make or break”) as no other source offers such curated event intel. Part of five AI-ready classes (I, II, III, V, X) for healthcare models.
  • Broader Context: Builds on series by emphasizing event-based data for partnerships/education; contrasts generic datasets with defensible, ethical expert interpretations for global equity (e.g., Pfizer’s AI Learning Lab).

AI Initiatives in Big Pharma (Focus on Pfizer)Reuses Grok prompt highlights, presented in a verbatim table:

Initiative Category
Description
Generative AI Tools
Save scientists up to 16,000 hours annually in literature searches and data analysis.
Drug Discovery Acceleration
Uses AI, supercomputing, and ML to streamline R&D timelines.
Clinical Trials & Regulatory Efficiency
Predictive Regulatory Tools; Decentralize Trials; Inventory management.
Disease Detection & Diagnostics
ATTR-CM Initiative; Rare diseases.
Generative AI & Operational Tools
Charlie Platform; Scientific Data Cloud (AWS-powered ML on centralized data); Amazon’s SageMaker/Bedrock for Manufacturing efficiency; Pfizer Foundation’s AI Learning Lab for equitable access to care and community tools.
Partnerships & Education
IMI Big Picture (3M-sample disease database); AI in Pharma AIPM Symposium (Drug discovery and Precision Medicine); Webinars on AI for biomedical data integration; Webinar on AI in Manufacturing.
Strategic Focus
$500M R&D reinvestment by 2026 for AI productivity; Part of $7.7B cost savings; Ethical AI with diverse DBs; Global biotech advances (e.g., China’s AI in CRISPR).
Mapping to LPBI’s Proprietary DataCore alignment table (verbatim extraction, linking Pfizer initiatives to Class III assets):
Pfizer AI Initiative
Class III Alignment (100 e-Proceedings + 50 Tweet Collections)
Generative AI Tools (16,000 hours saved)
(No specific mapping.)
Drug Discovery Acceleration
e-Proceedings of +100 TOP Conferences in Biotech, Medicine, Genomics, Precision Medicine (2013-2025). Frontier of Science presented; ONLY written record of events. Tweet Collections: Speaker QUOTES on record (not elsewhere available by name/affiliation).
Clinical Trials & Regulatory Efficiency
(No specific mapping.)
Disease Detection & Diagnostics (ATTR-CM, rare diseases)
(No specific mapping.)
Generative AI & Operational Tools (Charlie, AWS, etc.)
Ingest ALL e-Proceedings into Charlie Platform. Apply GPT: Training Data—one conference at a time; OR All Conferences on ONE subject (e.g., Immunotherapy, Oncolytic Virus Immunotherapy, Immune Oncology).
Partnerships & Education (IMI, AIPM, webinars)
Use Past Agendas/Speakers Lists/Topics for: Employee Training & Leadership Development; Build Future Conference Agendas.
Strategic Focus ($500M reinvestment, ethics)
Access to +100 e-Proceedings vs. None = Make or Break in Branding.

Examples: Subject clusters like Immunotherapy; resources include conference lists (2013-present) and e-proceedings deliverables.Methodologies and Frameworks

  • AI Training Pipeline: Ingest proceedings/tweets into Charlie/AWS (e.g., SageMaker); GPT processing per conference or theme for pre-training/fine-tuning/inference. Use ontology for semantic mapping; tweets for quote-based evals.
  • Productivity Model: Enhances Pfizer’s savings ($7.7B total) via event intel for education/partnerships; ethical diverse data for global grants (e.g., CRISPR AI).
  • Insights: Quote from Dr. Stephen J. Williams, PhD: Emphasizes strategic branding via access. Predicts revolution in AI education/leadership from historical agendas.

Conclusions and Implications

LPBI Group’s IP Asset Class III assets are “rare, defensible” for Big Pharma AI, powering from R&D acceleration to equitable care. Technical Implications: Enables theme-specific models (e.g., oncology conferences) for diagnostics/trials. Business Implications: Boosts ROI on $500M investments; licensing for symposia/webinars. Unique Insight: As the sole record of speaker insights, these outpace public data for “frontier” inference—key in series for holistic pharma AI moats.Promotional with resource links (e.g., IP portfolio, biotech conference lists). Complements prior pieces by adding temporal/event depth.
Let me know if you want series comparisons or dives into specific conferences!

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Real Time Conferecence Coverage: Advancing Precision Medicine Conference Philadelphia PA November 1,2 2024  Deliverables

Curator: Stephen J. Williams, Ph.D.

Below are deliverables in form of real Time conference coverage from the Advancing Precision Medicine Confererence held this year in Philadelphia, PA.  The meeting brought together scientists and clinicians to discuss the challenges faced in implementing genomics and proteomics into precision medicine decision making workflow.  As summarized by a future release at the 2025 ASCO, there are many issues and hindrances to incorporating data obtained from sequencing to make a personalized medicine strategy.  The meeting focused on two main disease states: oncology and cardiovascular however most of  the live meeting notes are from the oncology tract.  In general it was discussed there are three areas which need to be addressed to correctly and more frequently incorporate precision medicine and genomic panel testing into clinical decision making workflow:

  1.  access to testing panels and testing methodology for both doctors and patients
  2. expert interpretation of results including algorithms needed to analyze the data
  3. more education of molecular biology and omics data and methodology in medical school to address knowledge gaps between clinicians and scientists

The issues can be summarized by a JCO report to ASCO in 2022:

 Helen Sadik, PhD, Daryl Pritchard, PhD https://orcid.org/0000-0003-2675-0371 dpritchard@personalizedmedicinecoalition.org, Derry-Mae Keeling, BSc, Frank Policht, PhD, Peter Riccelli, PhD, Gretta Stone, BS, Kira Finkel, MSPH, Jeff Schreier, MBA, and Susanne Munksted, MS.  Impact of Clinical Practice Gaps on the Implementation of Personalized Medicine in Advanced Non–Small-Cell Lung Cancer. 2022: JCO Precision Oncology; Volume 6. https://doi.org/10.1200/PO.22.00246

Personalized medicine presents new opportunities for patients with cancer. However, many patients do not receive the most effective personalized treatments because of challenges associated with integrating predictive biomarker testing into clinical care. Patients are lost at various steps along the precision oncology pathway because of operational inefficiencies, limited understanding of biomarker strategies, inappropriate testing result usage, and access barriers. We examine the impact of various clinical practice gaps associated with diagnostic testing-informed personalized medicine strategies on the treatment of advanced non–small-cell lung cancer (aNSCLC).

The authors used a  Diaceutics’ Data Repository, a multisource database including commercial and Medicare claims and laboratory data from over 500,000 patients with non–small-cell lung cancer in the United States. They  analyzed the number of patients with newly diagnosed aNSCLC who could have, but did not, benefit from a personalized treatment. The analysis was focused on identifying the gaps and at which steps during care did gaps existed which precipitated either lack of use of precision medicine testing or incorrect interpretation of results.

Their conclusions were alarming:

Most patients with aNSCLC eligible for precision oncology treatments do not benefit from them because of clinical practice gaps. This finding is likely reflective of similar gaps in other cancer types. An increased understanding of the impact of each practice gap can inform strategies to improve the delivery of precision oncology, helping to fully realize the promise of personalized medicine.

The links to the live meeting notes are given below and collection of tweets follow (please note this meeting did not have a Twitter hashtag)

Real Time Coverage Advancing Precision Medicine Annual Conference, Philadelphia PA November 1,2 2024

https://pharmaceuticalintelligence.com/2024/11/01/real-time-coverage-advancing-precision-medicine-annual-conference-philadelphia-pa-november-12-2024/

Real Time Coverage Morning Session on Precision Oncology: Advancing Precision Medicine Annual Conference, Philadelphia PA November 1 2024

https://pharmaceuticalintelligence.com/2024/11/01/real-time-coverage-morning-session-on-precision-oncology-advancing-precision-medicine-annual-conference-philadelphia-pa-november-1-2024/

Real Time Coverage Afternoon Session on Precision Oncology: Advancing Precision Medicine Annual Conference, Philadelphia PA November 1 2024

https://pharmaceuticalintelligence.com/2024/11/01/real-time-coverage-afternoon-session-on-precision-oncology-advancing-precision-medicine-annual-conference-philadelphia-pa-november-1-2024/ 

Real Time Coverage Morning Session on Precision Oncology: Advancing Precision Medicine Annual Conference, Philadelphia PA November 2 2024

https://pharmaceuticalintelligence.com/2024/11/04/real-time-coverage-morning-session-on-precision-oncology-advancing-precision-medicine-annual-conference-philadelphia-pa-november-2-2024/ 

Tweet Collection

Tweet Collection Advancing Precision Medicine Conference November 1,2 2024 Philadelphia PA

 

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Real Time Conference Coverage: Advancing Precision Medicine Conference, Philadelphia, October 3–4, 2025 – DELIVERABLES

Conference Press Coverage and Scientific Reporting

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference

LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags:

@AdvancingPM  #WINSYMPO2025

Post #1

Select Conference Coverage 2025 Advancing Precision Medicine Conference, Philadelphia PA October 3-4 2025

https://pharmaceuticalintelligence.com/2025/10/02/conference-coverage-2025-advancing-precision-medicine-conference-philadelphia-pa-october-3-4-2025/

 

Post #2

Select Real Time Conference Coverage: Advancing Precision Medicine Conference,Morning Session Track 1 October 3 2025

https://pharmaceuticalintelligence.com/2025/10/03/real-time-conference-coverage-advancing-precision-medicine-conferencemorning-session-track-1-october-3-2025/

 

Post #3

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session Track 1 October 3 2025

https://pharmaceuticalintelligence.com/2025/10/03/real-time-conference-coverage-advancing-precision-medicine-conference-afternoon-session-track-1-october-3-2025/

 

Post #4

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Omics Session Track 2 October 3 2025

https://pharmaceuticalintelligence.com/2025/10/03/real-time-conference-coverage-advancing-precision-medicine-conference-afternoon-omics-session-track-2-october-3-2025/

 

Post #5

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, Early Morning Session Track 1 October 4 2025

https://pharmaceuticalintelligence.com/2025/10/04/real-time-conference-coverage-advancing-precision-medicine-conference-early-morning-session-track-1-october-4-2025/

 

Post #6

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, MidMorning Session Track 1 October 3 2025

https://pharmaceuticalintelligence.com/2025/10/04/real-time-conference-coverage-advancing-precision-medicine-conference-midmorning-session-track-1-october-3-2025/

 

Post #7

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session Track 1 October 3 2025

https://pharmaceuticalintelligence.com/2025/10/04/real-time-conference-coverage-advancing-precision-medicine-conference-afternoon-session-track-1-october-3-2025-2/

 

Post #8

Select Real Time Conference Coverage: Advancing Precision Medicine Conference, Late Morning Session Track 1 October 4 2025

https://pharmaceuticalintelligence.com/2025/10/04/real-time-conference-coverage-advancing-precision-medicine-conference-late-morning-session-track-1-october-4-2025/

 

Post #9

Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session, October 4 2025

https://pharmaceuticalintelligence.com/2025/10/04/real-time-conference-coverage-advancing-precision-medicine-conference-afternoon-session-october-4-2025/

 

 

 

 

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Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session October 4 2025

Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session  October 4 2025

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags

#AdvancingPM #precisionmedicine #WINSYMPO2025

1:40 – 2:30

AI in Precision Medicine

Dr. Ganhui Lan
Dr. Xiaoyan Wang
Dr. Ahmad P. Tafti
Jen Gilburg

Jen Gilburg (moderator)Deputy Secretary of Technology and Entrepreneurship, Dept. of Community and Economic Development, Commonwealth of Pennsylvania

  • AI will help reduce time for drug development especially in early phase of discovery but eventually help in all phases
  • Ganhui: for drug regulators might be more amenable to AI in clinical trials; AI may be used differently by clinicians
  • nonprofit in Philadelphia using AI to repurpose drugs (this site has posted on this and article will be included here)
  • Ganhui: top challenge of AI in Pharma; rapid evolution of AI and have to have core understanding of your needs and dependencies; realistic view of what can be done; AI has to have iterative learning; also huge vertical challenge meaning how can we allign the use of AI through the healthcare vertical layer chain like clinicians, payers, etc.
  • Ganhui sees a challenge for health companies to understand how to use AI in business to technology; AI in AI companies is different need than AI in healthcare companies
  • 95% of AI projects not successful because most projects are very discrete use

2:00-2:20

Building Precision Oncology Infrastructure in Low- and Middle-Income Countries

Razelle Kurzrock, MD

Sewanti Limaye, MD, Director, Medical & Precision Oncology; Director Clinical and Translational Oncology Research, Sir HN Reliance Foundation Hospital & Research Centre, Mumbai, India; Founder, Nova Precision AI; Co-Founder, Iylon Precision Oncology; Co-Chair, Asia Pacific Coalition Against Lung Cancer; Co-Chair,  Asia Pacific Immuno-Oncology; Member,  WIN Consortium

  • globally 60 precision initiatives but there really are because many in small countries
  • three out of five individuals in India die of cancer
  • precision medicine is a must and a hub and spoke model is needed in these places; Italy does this hub and spoke; spokes you enable the small places and bring them into the network so they know how and have access to precision medicine
  • in low income countries the challenge starts with biopsy: then diagnosis and biomarker is issue; then treatment decision a problem as they may not have access to molecular tumor boards
  • prevention is always a difficult task in LMICs (low income)
  • you have ten times more patients in India than in US (triage can be insurmountable)
  • ICGA Foundation: Indian Cancer Genome Atlas
  • in India mutational frequencies vary with geographical borders like EGFR mutations or KRAS mutations
  • genomic landscape of ovarian cancer in India totally different than in TCGA data
  • even different pathways are altered in ovarian cancer seen in North America than in India
  • MAY mean that biomarker panels need to be adjusted based on countries used in
  • the molecular data has to be curated for the India cases to be submitted to a tumor board
  • twenty diagnostic tests in market like TruCheck for Indian market; uses liquid biopsy
  • they are also tailoring diagnostic and treatment for India getting FDA fast track approvals

2:20-2:40

Co-targeting KIT/PDGRFA and Genomic Integrity in Gastrointestinal Stromal Tumors

Razelle Kurzrock, MD

Lori Rink, PhD, Associate Professor, Fox Chase Cancer Center

  • GIST are most common nesychymal tumor in GI tract
  • used to be misdiagnosed; was considered a leimyosarcoma
  • very asymptomatic tumors and not good prognosis
  • very refractory to genotoxic therapies
  • RTK KIT/PDGFRA gain of function mutations
  • Gleevec imatinib for unresectable GIST however vast majority of even responders become resistant to therapy and cancer returns
  • there is a mutation map for hotspot mutations and sensitivity for gleevec
  • however resistance emerged to ripretinib; in ATP binding pocket
  • over treatment get a polyclonal resistance
  • performed a kinome analysis; Wee1 looked like a potential target
  • mouse studies (80 day) showed good efficacy
  • avapiritinib ahs some neurotox and used in PDGFRA mut GIST model which is resistant to imitinib
  • but if use Wee1 inhibitor with TKI can lower dose of avapiritinib
  • cotargeting KIT/PDGFRA and WEE1 increases replicative stress
  • they are using PDX models to test these combinations
  • combination creates genomic instability

 

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Real Time Conference Coverage: Advancing Precision Medicine Conference, Late Morning Session Track 1 October 4 2025

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags

#AdvancingPM #precisionmedicine #WINSYMPO2025

SESSION 3

Advances in Precision Oncology:
From Genomics to Targeted Therapies

11:10-11:55

Breaking the Glass Ceiling: Targeting KRAS in Pancreatic Cancer

Razelle Kurzrock, MD
Razelle Kurzrock, MD

11:55-12:15

Charting the Future of Cancer Care: Precision Oncology and the Power of Genomics

Razelle Kurzrock, MD

12:15-12:35

Molecular Pathology as a Driver of Precision in Urological Cancers

Razelle Kurzrock, MD

12:30-12:40

Non – CME – dSTRIDE™-HR: A Functional Biomarker for In Situ, ‘real-time’ Detection and Quantification of Homologous Recombination Activity.

Magda Kordon-Kiszala, PhD

Magda Kordon-Kiszala, PhD, CEO and co-founder, intoDNA

12:35-12:55

Epigenetic Plasticity and Tumor Evolution: Mechanisms of Resistance in Precision Oncology

Johnathan R. Whetstine, PhD

Johnathan R. Whetstine, PhD, Director, Cancer Epigenetics Institute, Director, Geonomics Resource, Fox Chase Cancer Center

  • Title: Epigenetic plasticity a gatekeeper to generating extrachromosomal DNA amplification and rearrangements
  • genetic events in cancer are actually controlled not random as he says
  • Fox Chase Cancer Center Epigenetics Institute; 5th year goal to understand epigenetic mechanisms to understand resistance and biomarker development; bring others and break down silos;  they are expanding and hiring and bringing into a network; March 5 2026 5th Annual Symposium Philadelphia Franklin Institute
  • DNA amplification is also chromosomal: integrated same locus or different regions or chromosomal duplication
  • KDM4A epigenetic demethylase controls transiet site specific DNA re-replication; can have focal control of DNA regions
  • you can control regional control of like EGFR amplification
  • can use Cy3 to find local regions
  • KDM3B inhibitor promotes transiet copy gains in KMT2A/MLL
  • EHMT2 is lysine demethylase is a driver of this copy amplification
  • this demethylase can change expression locally in one hour.. very fast
  • demethylases are very specific for their gene locus they control and so this demethylase only controls MLL gene
  • doxorubicin topoisomerase inhibitor can cause LOH in MLL locus and methylase inhibitor can reverse this
  • over twenty combinatorial regulators so this field is just budding

11:30-12:30

Companion Diagnostics in Hereditary and Chronic Diseases – Development, Regulatory Approval, and Commercialization – Non-CME Discussion

Huw Ricketts

Huw Ricketts PhD, Senior Director, CLIA Business Development, QIAGEN

Tricia Carrigan

Tricia Carrigan, PhD, BC Biosolutions

Arushi Agarwal

Arushi Agarwal, MS,  Partner, Health Advances

Melissa Reuter

Melissa Reuter, MS, MBA, Director, Precision Medicine Program Strategy, GSK

  • This is a session panel Discussion on the current state of companion diagnostic development, not just in oncology.  Regulatory aspects will be discussed
  • Arushi: There are alot of opportunities in non-oncology areas for companion diagnostics, and time to development may be an obstacle
  • Huw Rickets:  From a development standpoint most people are not looking at the diagnostic side but more on the therapeutic side.
  • Tricia:  There needs to be a shift in oncology drug development world, and pharma sees developing diagnostic is too expensive.
  • Meliisa: They try to engage early with the agencies to understand the regulatory landscape; GSK is very strong in their oncology platform but there are gaps in diagnostics and non-oncology programs
  • Arushi: seems in Pharma oncology and non-oncology programs seems siloed
  • for non-oncology many of the biomarkers may be rare… well under 25% of population
  • Huw: Qiagen trying to develop diagnostics for Parkinson’s but those rare genetic diseases are easier to develop
  • Arushi: neurodegenerative, NASH, and immuno diseases are big areas where companies are looking to make companion diagnostics
  • Huw: kidney  disease is a big focus to develop companion diagnostics for

 

12:30-12:40

Non – CME – dSTRIDE™-HR: A Functional Biomarker for In Situ, ‘real-time’ Detection and Quantification of Homologous Recombination Activity.

Magda Kordon-Kiszala, PhD

Magda Kordon-Kiszala, PhD, CEO and co-founder, intoDNA

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WMIF25 – World Medical Innovation Forum, Sept. 15-17, 2025, Boston

Clinical experts, industry, investment leaders

https://2025.worldmedicalinnovation.org/

 

I, Aviva Lev-Ari, PhD, RN had covered the WMIF Conference since it was launched 11 years ago, including WMIF24.

 

#WMIF19 was a special conference with the focus on AI in Medicine

The #WMIF19 Influencers via ‘s  Hashtags http://bit.ly/WMIF19 – By Mentions and By Tweets Ranked #4: @pharma_BI and #2: @AVIVA1950, respectively. Ranked #3 via NodeXL’s Betweenness Centrality http://bit.ly/2KB6cPN

https://pharmaceuticalintelligence.com/2019/04/13/the-wmif19-influencers-via-symplurs-healthcare-hashtags-http-bit-ly-wmif19-by-mentions-and-by-tweets-ranked-4-pharma_bi-and-2-aviva1950-respectively-ranked-3-via-node/

 

9/15/2025 – 9/17/2025 – I did not attended In-person WMIF25.

  • I was invited to cover the event in real time, as follows:

From: “Doyle, Tracy” <tdoyle5@mgb.org>
Date: Wednesday, August 20, 2025 at 11:07 AM
Cc: “Yiannacopoulos, John” <john.yiannacopoulos@bofa.com>, “Doyle, Tracy” <tdoyle5@mgb.org>
Subject: Media Invite: World Medical Innovation Forum, Sept. 15-17, Boston — Clinical experts, industry, investment leaders

Media Invite: World Medical Innovation Forum: Monday, Sept. 15 — Wednesday, Sept. 17, Boston – Innovation at Scale

 

VIDEOS from this Conference on Youtube.com

https://www.youtube.com/results?search_query=WMIF

 

Selected Speakers:

Peter Arduini

CEO, GE HealthCare

 

Eliav Barr, MD

 

SVP, Chief Medical Officer and Head of Global Clinical Development, Merck

Meredith Fisher, PhD

 

Partner, Mass General Brigham Ventures

Jean-François Formela, MD

 

Partner, Atlas Venture

Adele Gulfo

 

President & CEO, Biopharma Strategies and Insights

Jason Hafler, PhD

 

Managing Director, Sanofi Ventures

Rajiv Kaul

 

Portfolio Manager, Fidelity Investments

Paul LaViolette

 

Managing Partner, SV Health Investors

David Liu, PhD

 

Richard Merkin Professor; Director, Merkin Institute of Transformative Technologies in Healthcare, Broad Institute

Paul Matsen

 

Chief Marketing and Communications Officer, Cleveland Clinic

Michael Mihm, PhD

 

Asset Lead, Astellas Pharma

Bernd Montag, PhD

 

CEO, Siemens Healthineers

Michael Quigley, PhD

 

Chief Scientific Officer, Global Head of Research, Sanofi

John Reed, MD, PhD

 

Executive Vice President, Innovation Medicine, R&D, Johnson & Johnson

David Reese, MD

 

EVP & Chief Technology Officer, Amgen

David Rhew, MD

 

Global Chief Medical Officer & VP Healthcare, Microsoft

Jay Rughani

 

Investing Partner, Andreessen Horowitz

Gaurav Singal, MD

 

Independent advisor and investor

Ariel Stern, PhD

 

Alexander von Humboldt Professor, Hasso Plattner Institute

Ricky Sun, PhD

 

Partner, Bain Capital

Andrew Trister, MD, PhD

 

Chief Medical and Scientific Officer, Verily [Google]

Christopher Viehbacher

 

CEO, Biogen

Erin Xie, PhD

 

Managing Director, BlackRock

 

1:1 firesides and panels with top experts including:

Amy Abernethy MD, PhD, Cofounder, Highlander Health

Peter Arduini, CEO, GE HealthCare

Jeffrey Balser MD, PhD, CEO, Vanderbilt University Medical Center

Eliav Barr MD, Chief Medical Officer, Merck

Tom Frohlich, CEO, Jade Biosciences

David Hyman MD, Chief Medical Officer, Eli Lilly

Rajiv Kaul, Portfolio Manager, Fidelity

Anne Klibanski MD, CEO, Mass General Brigham

Robert Langer ScD, Institute Professor, MIT

Anu Madgavkar, Partner, McKinsey Global Institute

Kevin Mahoney, CEO, UPenn Health System

Paul Matsen, Chief Marketing and Communications Officer, Cleveland Clinic

Bernd Montag PhD, CEO, Siemens Healthineers

Dinesh Patel, PhD, CEO, Protagonist Therapeutics

Xiayang Qiu, PhD, CEO, Regor Therapeutics

Mike Quigley, CSO, Sanofi

David Rhew, Global Chief Medical Officer & VP Healthcare, Microsoft

Ken Song, MD, CEO, Candid Therapeutics

David Sontag PhD, CEO, Layer Health

Chris Viehbacher, CEO, Biogen

 

Government and regulatory experts including:

Larry Bucshon MD, Senior Policy Advisor, Holland & Knight; Former U.S. Representative (Indiana, 2011–2025)

Robert Califf MD, Instructor in Medicine, Duke University; Former Commissioner, U.S. Food and Drug Administration

Susan Collins, Senior U.S. Senator from Maine

Maura Healey, Governor of the Commonwealth of Massachusetts

Susan Monarez PhD, Director, Centers for Disease Control and Prevention

 

Deep-Dive KOL and Focused Sessions including:

  • Emerging Treatments: Cancer, Cardiovascular Disease, Obesity & Metabolic Diseases
  • AI at the Bedside — Physician Co-Pilots
  • Upending the U.S. Care Model
  • Antimicrobial Resistance – An Urgent, Global Crisis
  • The Silver Tsunami – Unprecedented and Unceasing
  • Institutional Investor Perspectives
  • Innovations in Disability Technology
  • Consumerism in Healthcare
  • Tackling High-Priority Health Challenges in Under-Served Communities
  • Sleep – the Future of a Busy Market
  • Gene Editing – Precision Medicine in Practice
  • Hospital Venture Investing

 

Leading biotech and venture execs from companies such as:

  • Andreessen Horowitz
  • ArrePath
  • Bain Capital Life Sciences
  • Caris Life Sciences
  • Enable Ventures
  • Fidelity Investments
  • Intellia Therapeutics
  • Layer Health
  • Lightspeed Venture Capital
  • Novo Holdings Venture Investments
  • Viz.ai

Exclusive programming:  

  • First Look – 19 rapid-fire presentations on the latest research from leading Mass General Brigham scientists
  • Big Ideas – 100+ key opinion leaders in healthcare weigh in on solving the top un-met clinical needs in medicine today
  • Emerging Tech Zone – Hands-on exploration of some of the latest digital and AI-based healthcare technologies

 

 

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Real Time Conference Coverage: Advancing Precision Medicine Conference, Afternoon Session Track 1 October 3 2025

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags

#AdvancingPM #precisionmedicine #WINSYMPO2025

1:00 – 1:50

Lunch & Exhibits

TRACK 1  204BC

TRACK 2  204A

WIN SYMPOSIUM

MULTI-OMICS

1:50-4:05

SESSION 4

From Targets to Trials:
Translating Discovery into Impact

1:50-2:10

Beyond Checkpoint Inhibitors: Targeted Immunotherapeutic Approaches for the Management of Solid Tumors

Andrea Ferreira-Gonzalez

2:10-2:30

Implementing Molecular Profiling in Early Phase Clinical Trials: Precision from Bench to Bedside

Andrea Ferreira-Gonzalez

2:30-2:40

Q&A

Andrea Ferreira-Gonzalez
Andrea Ferreira-Gonzalez

2:40-3:20

Non- CME Session: Venture Philanthropy

Andrea Ferreira-Gonzalez

Eric Heil, MBA, Managing Partner, Medical Excellence Capital

John Lehr, President & CEO, Parkinson's Foundation

John Lehr, President & CEO, Parkinson’s Foundation

Dr. Blaine Robinson

Dr. Blaine Robinson, PhD, Vice President of the Therapy Acceleration Program (TAP), Blood Cancer United

3:20-4:10

eNSCLC Testing

Andrea Ferreira-Gonzalez

4:10 – 4:25

Break and Exhibits

TRACK 1  204BC

TRACK 2  204A

WIN SYMPOSIUM

MULTI-OMICS

4:25-6:45

4:25-5:15

Transforming Pediatric Oncology: The Power of Precision Medicine

Andrea Ferreira-Gonzalez

Giselle L. Sholler, MD, Division Chief, Pediatric Hematology/Oncology/BMT, Penn State Hershey Children’s Hospital; Professor, Pediatrics and Pharmacology; Founder & Chair, Beat Childhood Cancer Consortium

Andrea Ferreira-Gonzalez

Wei Zhang, PhD, Hanes and Willis Family Professor in Cancer; Director, Cancer Genomics and Precision Oncology, Wake Forest Baptist Comprehensive Cancer Center

Andrea Ferreira-Gonzalez

Elias Sayour, MD, PhD, Professor, Neurosurgery and Pediatrics;  Assistant Dean,  Clinical Research, UF College of Medicine, Program Co-leader,  UF Health Cancer Center Immuno-Oncology and Microbiome (IOM) Program

Andrea Ferreira-Gonzalez

Milan Radovich, PhD, Senior Vice President, Chief Scientific Officer, Caris Life Sciences

Andrea Ferreira-Gonzalez

Pei Wang, PhD, Professor, Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai

Abigail Moore

5:15-5:25

Informing therapy decisions for improved patient care

Ashley Varghese, PharmD, RPh

5:25-5:50

Liquid Biopsies and Resistance Monitoring in Targeted Therapies 

Andrea Ferreira-Gonzalez

Pashtoon Kasi, MD, MS, Medical Director, GI Medical Oncology, City of Hope

5:50-6:10

Liquid Biopsies in Clinical Practice: Transforming Precision Oncology Through Molecular Monitoring

Andrea Ferreira-Gonzalez

Hatim Husain, MD, Associate Professor, University of California, San Diego 

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Real Time Conference Coverage: Advancing Precision Medicine Conference, MidMorning Session Track 1 October 3 2025

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags

#AdvancingPM #precisionmedicine #WINSYMPO2025

0:40 – 11:10

Break and Exhibits

TRACK 1  204BC

TRACK 2  204A

WIN SYMPOSIUM

MULTI-OMICS

11:10 – 1:10

SESSION 2

The Evolution of Precision Oncology:

Integrating MRD, AI, and Beyond

11:10-12:00

Precision Cancer Consortium

Andrea Ferreira-Gonzalez
Andrea Ferreira-Gonzalez

Shruti Mathur, MS, Pharma Diagnostic Strategy Leader, Global Product Strategy (GPS), Genentech

Andrea Ferreira-Gonzalez

Daryl Pritchard, PhD, Interim President, Personalized Medicine Coalition

Andrea Ferreira-Gonzalez

Keith T. Flaherty, MD, FAACR, Director of Clinical Research, Massachusetts General Cancer Center; Professor of Medicine, Harvard Medical School;
President-Elect: 2025-2026, American Association for Cancer Research (AACR) 

SESSION 3

The Shifting Landscape:

Tumor Plasticity and Resistance

12:00-12:20

Mathematical and Evolutionary Modeling in Precision Radiation Oncology

Andrea Ferreira-Gonzalez

Jacob Scott, MD, DPhil, Professor and Staff Physician-Scientist, CWRU School of Medicine and Cleveland Clinic

12:20-12:40

Plasticity and Persistence: The Role of EMT in Cancer Progression and Therapy Resistance

Andrea Ferreira-Gonzalez

Sendurai A. Mani, PhD, Professor of Pathology and Laboratory Medicine, Brown University; Associate Director of Translational Oncology, Brown University Legorreta Cancer Center

12:40-1:00

Targeting Molecularly Defined Subsets: Challenges in Translational Oncology

Andrea Ferreira-Gonzalez

Benedito A. Carneiro, MD, MS, Director, Clinical Research
Director, Cancer Drug Development; Associate Director, Division of Hematology/Oncology
Legorreta Cancer Center, Brown University Health

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Real Time Conference Coverage: Advancing Precision Medicine Conference, Early Morning Session Track 1 October 4 2025

Reporter: Stephen J. Williams, PhD

Leaders in Pharmaceutical Business Intellegence will be covering this conference LIVE over X.com at

@pharma_BI

@StephenJWillia2

@AVIVA1950

@AdvancingPM

using the following meeting hashtags

#AdvancingPM #precisionmedicine #WINSYMPO2025

 

8:55 – 10:35

SESSION 1

Precision For All:

Global Access, Real Cases, and Implementation Science

 

8:55-9:15

Results and Future Direction from WIN’s Data Science Paper

Razelle Kurzrock, MD

9:15-9:55

When Precision Gets Personal: WIN Consortium International Molecular Tumor Board Live

Andrea Ferreira-Gonzalez
Razelle Kurzrock, MD

Razelle Kurzrock, MD, FACP, Chief Medical Officer, WIN Consortium; Professor of Medicine, Associate Director, Clinical Research, Linda T. and John A. Mellowes Endowed Chair of Precision Oncology, MCW Cancer Center and Linda T. & John A. Mellowes Center for Genomic Sciences and Precision Medicine

Notes from Live Tumor Board from Live Tweets

Tumor board Live… Molecular profiling great for identifying synthetic lethal combinations work very well… Many oncologist not accepting recommendations of molec tumor board

Tumor board Live . Oncologists don’t always accept tumor board recommendations based on molecular profiling… Dr Baptiste at first felt constrained to use single agent but WINTER combo trial with molec profiling better

Tumor board Live… Oncologist may give pushback when molecular therapeutic targets identified.. like when methylomics give a result and tumor board suggest temazolamide

Tumor board Live… Oncologist may give pushback when molecular therapeutic targets identified.. like when methylomics give a result and tumor board suggest temazolamide

Tumor board Live… Oncologist may give pushback when molecular therapeutic targets identified.. like when methylomics give a result and tumor board suggest temazolamide

Pemetrexemed not always working but MTAP inhibitions may work

Tumor board Live… Discussion of ovarian cancer case women first presented with CRC BRCA mut but failed PARP inhibitor board is looking at immunotherapy NGS IHC performed

#WINconsortium

Fusions being detected by RNAseq at rate of 100 per month

Tumor board Live…. Theranostics are becoming part of molec tumor board … Radio labeled dual diagnostic therapeutic antibodies

Tumor board Live… Molecular profiling great for identifying synthetic lethal combinations work very well… Many oncologist not accepting recommendations of molec tumor board

SESSION 2

Expanding the Precision Frontier

9:55-10:25

Precision Oncology in the Immunotherapy Era: Biomarkers and Clinical Trial Innovation

Razelle Kurzrock, MD

Lillian Siu, MD, President, AACR 2025-2026; Director, Phase I Clinical Trials Program; Co-Director, Robert and Maggie Bras and Family Drug Development Program Clinical Lead, Tumor Immunotherapy Program; BMO Chair, Precision Cancer Genomics, Princess Margaret Cancer Centre Professor of Medicine, University of Toronto

  • Princess Margaret CC went to Merck got pembrolizumab from them but built a team platform of clinicians and scientists to work on INSPIRE trial
  • $11 million of grants, 13 major papers, great team science
  • did ctDNA from liquid biopsy and also looked at methylation patterns in cfDNA
  • looked at IFN stimulation and outcome to pembrolizumab
  • retro transposable elements found in INSPIRE program, maybe a predictor of immune sensitivity
  • they were able to correlate some of their findings with spatial omics
  • using spatial data they could look at hot versus cold head and neck cancer
  •  factors for response to immunotherapy: TMB, t cell infiltrate,  PDL1 etc
  • using AI with IHC slides as well as NGS data sets
  • as clinical trials become multiomics and AI with multiomics platforms data sharing will be critical for success

10:25 – 10:35

The Microbiome and Its Role in Cancer Development and Treatment Response

Razelle Kurzrock, MD

Sabine Hazan, MD, CEO, Ventura Clinical Trials; CEO, Progenabiome

  • microbiome research at the infancy so we don’t know much when comes to oncology
  • we need to compare microbiome between persons using NGS and other omics
  • we all have different microbiome even though microbiome ‘healthy’
  • lots of factors affect microbiome including surgery
  • families are similar in their microbiome but when looking at Alzheimers there are differences
  • first lab to find whole COVID in the stools
  • virus was different in different people, difference spike proteins. Virus mutates from lung to stool (gut)
  • in intrafamily patients had different microbiome upon COVID infection
  • bifodobacteria was found as a major part of microbiome altered in COVID but also lots of other diseases
  • lots of examples of host microbial symbiosis
  • they had an instance with throat tumor treated with microbiome and tumor receded without chemo
  • in a glioblastoma microbiome adjustment helped but changed positive response to immunotherapy

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