Feeds:
Posts
Comments

Archive for the ‘Conference Coverage with Social Media’ Category


Tweet Collection by @pharma_BI and @AVIVA1950 and Re-Tweets for e-Proceedings 14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

Real Time Press Coverage: Aviva Lev-Ari, PhD, RN

 

e-Proceedings 14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

Real Time Press Coverage: Aviva Lev-Ari, PhD, RN

Founder & Director, LPBI Group

https://pharmaceuticalintelligence.com/2020/07/28/14th-annual-biopharma-healthcare-summit-friday-september-4-2020-8-am-est-to-3-30-pm-est-virtual-edition/

 

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Hal Barron, Chief Scientific Officer and President R&D, GlaxoSmithKline GWAS not easy to find which gene drives the association  Functional Genomics gene by gene with phenotypes using machine learning significant help

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Hal Barron, Chief Scientific Officer and President R&D, GSK GWAS not easy to find which gene drives the association  Functional Genomics gene by gene with phenotypes using machine learning significant help

Srihari Gopal
@sgopal2

Enjoyed hearing enthusiasm for Neuroscience R&D by Roy Vagelos at #USAIC20. Wonderful interview by Mathai Mammen

Image

1
2
Show this thread

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Nina Kjellson, General Partner, Canaan Data science is a winner in Healthcare Women – Data Science is an excellent match

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Arpa Garay, President, Global Pharmaceuticals, Commercial Analytics, Merck & Co. Data on Patients and identification who will benefit fro which therapy  cultural bias risk aversion

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Najat Khan, Chief Operating Officer, Janssen R&D Data Sciences, Johnson & Johnson Data Validation  Deployment of algorithms embed data by type early on in the crisis to understand the disease

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Sastry Chilukuri, President, Acorn AI- Medidata Opportunities in Data Science in Paharma COVID-19 and Data Science

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Maya Said, Chief Executive Officer, Outcomes4Me Cancer patients taking change of their care Digital Health – consumerization of Health, patient demand to be part of the decision, part the information FDA launched a Program Project Patient Voice

USAIC
@USAIC

We’re taking a quick break at #USAIC20 before our next panel on rare diseases starts at 12:20pm EDT. USAIC would like to thank our Sponsors and Partners for supporting this year’s digital event.

Image

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Roy Vagelos, Chairman of the Board, Regeneron HIV-AIDS: reverse transcriptase converted a lethal disease to a chronic disease, tried hard to make vaccine – the science was not there

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Roy Vagelos, Chairman of the Board, Regeneron Pharmaceuticals Congratulates Big Pharma for taking the challenge on COVID-19 Vaccine, Antibody and anti-viral Government funding Merck was independent from Government – to be able to set the price

1

Dr Kapil Khambholja
@kapilmk

Christopher Viehbacher, Gurnet Point Capital touches very sensitive topic at #USAIC20 He claims that we are never going to have real innovation out of big pharma! Well this isn’t new but not entirely true either… any more thoughts?
1
1
Show this thread

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Daphne Zohar, Founder & CEO, PureTech Health Disease focus, best science is the decision factors

1

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Christopher Viehbacher, Managing Partner, Gurnet Point Capital Dream of every Biotech – get Big Pharma coming to acquire and pay a lot Morph and adapt

anju ghangurde
@scripanjug

Biogen’s chair Papadopoulos big co mergers is an attempt to solve problems; typically driven by patent expirations.. #usaic20

2

anju ghangurde
@scripanjug

Chris Viehbacher/Gurnet Point Capital on US election: industry will work with whoever wins; we’ll have to ‘morph & adapt’ #usaic20

1

Dr Kapil Khambholja
@kapilmk

of

talks about various philosophies and key reasons why certain projects/molecules are killed early. My counter questions- What are chances of losing hope little early? Do small #biopharma publish negative results to aid to the knowledge pool? #USAIC20

Image

2
2
Show this thread

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Laurie Glimcher, President & CEO, Dana-Farber Cancer Institute DNA repair and epignetics are the future of medicine

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Laurie Glimcher, President & CEO, Dana-Farber Cancer Institute COlonorectal cancer is increasing immuno therapy 5 drugs marketed 30% cancer patients are treated early detection key vs metastatic 10% of cancer are inherited treatment early

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Rehan Verjee, President, EMD Serono Charities funding cancer research – were impacted and resources will come later and in decreased amount New opportunities support access to Medicine improve investment across the board

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Philip Larsen, Global Head of Research, Bayer AG Repurposing drugs as antiviral from drug screening innovating methods Cytokine storm in OCVID-19 – kinase inhibitors may be antiviral data of tested positive allows research of pathway in new ways

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Laurie Glimcher, President & CEO, Dana-Farber 3,000 Telemedicine session in the first week of the Pandemic vs 300 before – patient come back visits patient happy with Telemedicine team virtually need be reimbursed same rate working remotely

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Raju Kucherlapati, Professor of Genetics, Harvard Medical School New normal as a result of the pandemic role of personalized medicine

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Rehan Verjee, President, EMD Serono entire volume of clinical trials at Roche went down same at EMD delay of 6 month, some were to be initiated but was put on hold Charities funding cancer research were impacted and resources will come later smaller

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Laurie Glimcher, President & CEO, Dana-Farber Cancer Institute Dana Farber saw impact of COVID-19 on immunosuppressed patients coming in for Cancer Tx – switch from IV Tx to Oral 96% decrease in screenings due to Pandemic – increase with Cancer

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Kenneth Frazier, Chairman of the Board and Chief Executive Officer, Merck & Co. Pharma’s obligation for next generations requires investment in R&D vs Politicians running for 4 years Patients must come first vs shareholders vs R&D investment in 2011

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Kenneth Frazier, Chairman of the Board and Chief Executive Officer, Merck & Co. Antibiotic research at Merck – no market incentives on pricing for Merck to invest in antibiotics people will die from bacterial resistance next pandemic be bacterial

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Kenneth Frazier, Chairman of the Board and Chief Executive Officer, Merck & Co. Strategies of Merck = “Medicine is for the People not for Profit” – Ketruda in India is not reembureable in India and million are in need it Partnership are encouraged

Dr Kapil Khambholja
@kapilmk

Chairman Stelios Papadopoulos asks #KennethFrazier if wealthy nations will try to secure large proportion of #COVID19 drugs/vaccines. #KennethFrazie rightly mentions: pharma industry’s responsibility to balance the access to diff countries during pandemic. #USAIC20

1
3
Show this thread

Dr Kapil Khambholja
@kapilmk

Almost 60% participants at #USAIC20 feel that MNCs are more likely to run their #clinicalTrials in #INDIA seeing changing environment here, reveals the poll. Exciting time ahead for scientific fraternity as this can substantially increase the speed of #DrugDevelopment globally

Clapping hands sign

Image

1
1
Show this thread

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Barry Bloom, Professor & former Dean, Harvard School of Public Health Vaccine in clinical trials, public need to return for 2nd shot, hesitancy Who will get the Vaccine first in the US  most vulnerable of those causing transmission Pharma’s risk

4

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr. Barry Bloom, Professor & former Dean, Harvard School of Public Health Testing – PCR expensive does not enable quick testing is expensive result come transmission occurred Antibody testing CRISPR test based Vaccine in clinical trials

1

Aviva Lev-Ari
@AVIVA1950

#USAIC20 Dr Andrew Plump, President of R&D, Takeda Pharmaceuticals COllaboration effort around the Globe in the Pandemic therapy solutions including Vaccines

Read Full Post »


Tweets by @pharma_BI and @AVIVA1950 @ 2020 State of Possible Conference, MassBio’s VIRTUAL Annual Meeting, August 26 – 27, 2020

Real Time press coverage: Aviva Lev-Ari, PhD, RN

 

2020 State of Possible Conference, MassBio’s VIRTUAL Annual Meeting, August 26 – 27, 2020

Real Time press coverage: Aviva Lev-Ari, PhD, RN

https://pharmaceuticalintelligence.com/2020/02/21/2020-state-of-possible-conference-massbios-annual-meeting-march-25-26-2020-sonesta-hotel-cambridge-ma/

 

Aviva Lev-Ari
@AVIVA1950

2020 State of Possible Conference, MassBio’s VIRTUAL Annual Meeting, August 26 – 27, 2020
2020 State of Possible Conference, MassBio’s VIRTUAL Annual Meeting, August 26 – 27, 2020 Leaders in Pharmaceutical Business Intelligence (LPBI) Group will cover this event in REAL TIME…
pharmaceuticalintelligence.com
2

Aviva Lev-Ari
@AVIVA1950

Thomas McCourt President Ironwood Pharmaceuticals, Inc. Clinical trials many are STUCK – solve problems calls for adoption of all companies to digital platforms Entrepreneurial spirit in Kendall square took away the prime position of CA Biotech

Aviva Lev-Ari
@AVIVA1950

Thomas McCourt President Ironwood Pharmaceuticals, Inc. GI disease in Patients – My Gi Health started in NIH – symptoms of GI diseases GI entrepreneurs to build a smart e-Tool to analyze the GI Symptoms  few thousand Patients

Aviva Lev-Ari
@AVIVA1950

Nick Dougherty Managing Director MassChallenge HealthTech Around the World communities, MA Biotech infrastructure  MassChallenge HealthTech: In Mexico, in Israel in Switzerland Becoming virtual instantly in MARCH 2020 More locations pick up scale up

1

Aviva Lev-Ari
@AVIVA1950

Naomi Fried Founder CEO Health Innovation Strategies MA best Hospitals: MGH-BWH, Beth Israel-Lahey Clinic, Stuart BC/BS Medical Schools Clusters in Biotech & Digital Health Counsel  Definition of Community changed in the COVID-19 Era

Aviva Lev-Ari
@AVIVA1950

Stephen Bernstein McDermott Will & Emery LLP Virtual Bench science Life sciences Products; Deploying a compound, provider responsible for the cost or how the Reimbursement will work Consumer & Patients: Specialty Pharmacy  collaborations by planning

Aviva Lev-Ari
@AVIVA1950

Stephen Bernstein McDermott Will & Emery LLP Webinars and Zooms allows communication we will see more innovations – Flatten the World Greater isolation US is expected to lead collaborate is NOW home based no travel creative  Virtual Clinical Trials

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio Precision Medicine Group Network biology modeling – helps inform chemistry models: Cell line in Mice translation to Human in pancreatic cancer cell line  Pessimistic view: Long way to go end point most time

Aviva Lev-Ari
@AVIVA1950

Rachel Hodos Senior AI Scientist BenevolentAI Panelist Pick Targets AI is a Possible dream trusted a drug in human

Aviva Lev-Ari
@AVIVA1950

Nora Khaldi Founder and CSO Nuritas AI biological data is early while relying on that knowledge identify drug safe for human is possible I believe AI – take a molecule to humans 99% working in humans AI teated and validated in vitro

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Merck High dimensional spaces sample comparison Find therapies for Humans in the absence of having Humans participating, data on human is BIASED by drugs history Drugable identify interventions translatable to Humans pathway-based

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio, Precision Medicine Group Chemistry in developing drugs is complex Network biology modeling – helps inform chemistry models: Cell line in Mice translation to Human in pancreatic cancer cell line

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio Precision Medicine Group technology enable company clinical data analysis of data clinical trials ML prior knowledge network biology drive inside MOA prioritize indications Chemistry in developing drugs complex

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Computational and Structural Chemistry Merck metabolomics evolving proteins analyzing data access to compute power data acquisition and storage – High dimensional spaces sample comparison

1

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Computational and Structural Chemistry Merck Drug Target identification Drug Discovery – ML since 1980s Identify molecules syntesis prediction physico space – physiological systems Transcriptomics, single cell biomarkers proteomics

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio Precision Medicine Group Network biology modeling – helps inform chemistry models: Cell line in Mice translation to Human in pancreatic cancer cell line  Pessimistic view: Long way to go end point most time

Aviva Lev-Ari
@AVIVA1950

Rachel Hodos Senior AI Scientist BenevolentAI Panelist Pick Targets AI is a Possible dream trusted a drug in human

Aviva Lev-Ari
@AVIVA1950

Nora Khaldi Founder and CSO Nuritas AI biological data is early while relying on that knowledge identify drug safe for human is possible I believe AI – take a molecule to humans 99% working in humans AI teated and validated in vitro

Aviva Lev-Ari
@AVIVA1950

Thomas McCourt President Ironwood Pharmaceuticals, Inc. Clinical trials many are STUCK – solve problems calls for adoption of all companies to digital platforms Entrepreneurial spirit in Kendall square took away the prime position of CA Biotech

Aviva Lev-Ari
@AVIVA1950

Thomas McCourt President Ironwood Pharmaceuticals, Inc. GI disease in Patients – My Gi Health started in NIH – symptoms of GI diseases GI entrepreneurs to build a smart e-Tool to analyze the GI Symptoms  few thousand Patients

Aviva Lev-Ari
@AVIVA1950

Nick Dougherty Managing Director MassChallenge HealthTech Around the World communities, MA Biotech infrastructure  MassChallenge HealthTech: In Mexico, in Israel in Switzerland Becoming virtual instantly in MARCH 2020 More locations pick up scale up

1

Aviva Lev-Ari
@AVIVA1950

Naomi Fried Founder CEO Health Innovation Strategies MA best Hospitals: MGH-BWH, Beth Israel-Lahey Clinic, Stuart BC/BS Medical Schools Clusters in Biotech & Digital Health Counsel  Definition of Community changed in the COVID-19 Era

Aviva Lev-Ari
@AVIVA1950

Stephen Bernstein McDermott Will & Emery LLP Virtual Bench science Life sciences Products; Deploying a compound, provider responsible for the cost or how the Reimbursement will work Consumer & Patients: Specialty Pharmacy  collaborations by planning

Aviva Lev-Ari
@AVIVA1950

Stephen Bernstein McDermott Will & Emery LLP Webinars and Zooms allows communication we will see more innovations – Flatten the World Greater isolation US is expected to lead collaborate is NOW home based no travel creative  Virtual Clinical Trials

Aviva Lev-Ari
@AVIVA1950

Kenneth Anderson Director, Multiple Myeloma Center Dana-Farber Cancer Institute Hematologic Division – African Americans  Change paradigm of clinical trials Geraldine Feraro was patient at DFCI Tom Bracow patient at DFCI  STEM for girls 6-12 grades

Aviva Lev-Ari
@AVIVA1950

Kenneth Anderson Director, Multiple Myeloma Center Dana-Farber Cancer Institute Multiple Myeloma – 23 drugs approved by FDA Dana-Farber Cancer Institute with Sanofi collaboration Foundations stepped forward to study Multiple Myeloma FDA motivated

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Merck High dimensional spaces sample comparison Find therapies for Humans in the absence of having Humans participating, data on human is BIASED by drugs history Drugable identify interventions translatable to Humans pathway-based

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio, Precision Medicine Group Chemistry in developing drugs is complex Network biology modeling – helps inform chemistry models: Cell line in Mice translation to Human in pancreatic cancer cell line

Aviva Lev-Ari
@AVIVA1950

Renée Deehan-Kenney PhD, VP, QuartzBio Precision Medicine Group technology enable company clinical data analysis of data clinical trials ML prior knowledge network biology drive inside MOA prioritize indications Chemistry in developing drugs complex

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Computational and Structural Chemistry Merck metabolomics evolving proteins analyzing data access to compute power data acquisition and storage – High dimensional spaces sample comparison

1

Aviva Lev-Ari
@AVIVA1950

Juan Alvarez AVP, Computational and Structural Chemistry Merck Drug Target identification Drug Discovery – ML since 1980s Identify molecules syntesis prediction physico space – physiological systems Transcriptomics, single cell biomarkers proteomics

Read Full Post »


14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

Real Time Press Coverage: Aviva Lev-Ari, PhD, RN

Founder & Director, LPBI Group

 

Tweet Collection by @pharma_BI and @AVIVA1950 and Re-Tweets for e-Proceedings 14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

Real Time Press Coverage: Aviva Lev-Ari, PhD, RN

https://pharmaceuticalintelligence.com/2020/09/04/tweet-collection-by-pharma_bi-and-aviva1950-and-re-tweets-for-e-proceedings-14th-annual-biopharma-healthcare-summit-friday-september-4-2020-8-am-est-to-3-30-pm-est-virtual-editio/

 

 

 

http://www.usaindiachamber.org

 

 2021 summit- June 22. Marriott Cambridge, Massachusetts, USA

 

LPBI’s 2020 VISION

@pharma_BI

@AVIVA1950

#USAIC20

 

 

USAIC has created an ecosystem committed to driving a global dialogue on BioPharma & Healthcare innovation, attracting a diverse mix of senior industry professionals and catalyzing partnerships, new ideas, networks and regulatory reform. This unique platform creates mutually beneficial opportunities and relationships for the global Life Sciences & Healthcare industry.

14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

 

Speakers


Kenneth Frazier
Chairman of the Board & CEO
Merck & Co.

Dr. Andrew Plump
President of R&D
Takeda Pharmaceuticals

Dr. Laurie Glimcher
President & CEO
Dana-Farber Cancer Institute

Dr. Roy Vagelos
Chairman of the Board
Regeneron

Dr. Stelios Papadopoulos
Chairman of the Board
Biogen

Dr. Mathai Mammen
Global Head of Janssen R&D
Johnson & Johnson

Christopher Viehbacher
Managing Partner
Gurnet Point Capital

Hari Bhartia
Founder & Co-Chairman
Jubilant Bhartia Group

Dr. Hal Barron
President, R&D and CSO
GlaxoSmithKline

Prof. K. Vijay Raghavan
Principal Scientific Advisor
Government of India

Sanat Chattopadhyay
President- Merck Manufacturing Division
Merck & Co.

Dr. George Yancopoulos
Co-Founder, President & CSO
Regeneron

Kiran Mazumdar Shaw
Executive Chairperson
Biocon

Dr. Elias Zerhouni
Professor Emeritus
Johns Hopkins University

Dr. David Reese
Executive Vice President- R&D
Amgen

Dr. Alfred Sandrock
Executive Vice President, R&D
Biogen

Dr. Naresh Trehan
Chairman
Medanta – the Medicity

Dr. Najat Khan
Chief Operating Officer, Data Sciences
Janssen- Johnson & Johnson

Dr. Richard Hatchett
Chief Executive Officer
CEPI

Amitabh Kant
Chief Executive Officer
NITI Aayog

Dr. Martin Mackay
Co-Founder
Rallybio

Dr. Daniel Curran
Head of the Rare Diseases TA
Takeda Pharmaceuticals

Daphne Zohar
Founder & CEO
PureTech Health

Dr. David Meeker
Chairman & CEO
Rhythm Pharmaceuticals

Dr. John Orloff
EVP and Head of R&D
Alexion

Dr. Mandeep Bhandari
Joint Secretary
Ministry of Health, India

Dr. Barry Bloom
Professor & former Dean
Harvard School of Public Health

Dr. Anne Heatherington
Head of Data Sciences Institute
Takeda Pharmaceuticals

Dr. Philip Larsen
Global Head of Research
Bayer AG

Dr. Timothy Yu
Assistant Professor in Pediatrics
Harvard Medical School

Rehan Verjee
President
EMD Serono

Sastry Chilukuri
Executive Vice President
Medidata

Arpa Garay
President, Commercial Analytics
Merck & Co.

Dr. William Chin
Professor of Medicine, Emeritus
Harvard Medical School

Dr. V G Somani
Drugs Controller General of India
Government of India

Dr. Rajeev Venkayya
President-Global Vaccines
Takeda

Dr. Steve Uden
Co-Founder
Rallybio

Muna Bhanji
SVP, Global Market Access
Merck & Co.

Dr. Maya Said
Chief Executive Officer
Outcomes4Me

Dr. Raju Kucherlapati
Professor of Genetics
Harvard Medical School

Dr. Tony Ho
Head of R&D
CRISPR Therapeutics

Dr. Sanjeev Sinha
Professor of Medicine
All India Institute of Medical Sciences

Nina Kjellson
General Partner
Canaan

Dr. Michael Rosenblatt
Chief Medical Officer
Flagship Pioneering

Dr. Shiv Kumar Sarin
Director
Institute of Liver & Biliary Sciences

Matt Wilsey
Co-Founder & Chairman
Grace Science Foundation

Dr. Samuel Waksal
Founder
Meira GTx

Dr. Alise Reicin
Former President, Global Clinical Dev.
Celgene

Dr. Toni Choueiri
Director
Lank Center for Genitourinary Oncology
Dana-Farber Cancer Institute

Dr. Dhaval Patel
EVP & Chief Scientific Officer
UCB

Dr. Nirmal Kumar Ganguly
Former Director General
Indian Council of Medical Research

Dr. Peter Mueller
President
The Muller Health Foundation

Dr. Timothy Clackson
President & CTO
Xilio Therapeutics
 

 

14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020,

8 AM EST to 3-30 PM EST – Virtual Edition

 

Chair and Master of Ceremonies (Emcee)– Dr. Andrew Plump, President of R&D, Takeda Pharmaceuticals

Timings are Eastern Standard Time (EST)

Time Topic
8 AM – 8-10 AM Welcome addressKarun Rishi, President, USAIC

  • COVID-19 Pandemic is a Global crisis
  • India can play a special role in R&D and in Manufacturing including Vaccine development

Opening commentsDr Andrew Plump, President of R&D, Takeda Pharmaceuticals

  • Global Summit around the World – JP Morgan of the East as we were called – it is Now a Global Conference vs East Coast
  • Record number of Drugs approved as New Drugs with special quality
  • explosion of modality of therapies to include Gene Therapy
  • Billion underserved vs N-of-One drug
  • India’s President Modi allow healthcare access to 1/2Billion
  • collaboration across the World COVID Alliance in vaccine development
  • Global effort, China recovery is remarkable
  • India battle the infection and it is growing – Public Health
  • Remarkable Speakers
8-10 AM – 8-50 AM Panel Discussion- COVID-19: Where are we now? Where are we going?

Panelists:
Dr. Barry Bloom, Professor & former Dean, Harvard School of Public Health

  • Testing – PCR expensive does not enable quick testing is expensive result come transmission occurred
  • Antibody testing
  • CRISPR test based
  • Vaccine in clinical trials, public need to return for 2nd shot, hesitancy
  • Who will get the Vaccine first? in the US  most vulnerable of those causing transmission
  • Pharma takes risk when efficacious level is unknown
    Dr. George Yancopoulos, Co-Founder, President & CSO, Regeneron
  • Repurpose – be careful
  • Ebola vaccine development approach is been REUSED for COVID-19
  • Existential threat by Disease – preparedness is ridiculous as size of investment – far where we need to be
  • Untreatable disease burden COVID-19 cost of healthcare calls massive increases as a society and Private sector Moderna invested in new technology from Academe to the Industry
  • Universal HealthCare will cripple the the healthcare systems
    Kiran Mazumdar-Shaw, Executive Chairperson, Biocon
  • Safety in proof of concept
  • Children focus for emergency use
  • validation of repurpose drugs
  • oral vaccine involve sequential processing, approval and TRUST,
  • concerns about risks
  • accelerate the process is the opportunity
    Dr. Rajeev Venkayya, President of the Global Vaccine Business Unit, Takeda
  • Public confidence in COVID-19 Vaccine
  • The Group with concerns at present is larger than 15 years ago due to the accelerate process od the development process
  • political influences on CDC emergency authorization given prior to election
  • hesitancy – influence of social media, conspiracies
  • Transparency by Pharma and by Regulatory Agencies
  • Independent reviews
    Dr. Richard Hatchett, CEO, Coalition for Epidemic Preparedness Innovations (CEPI)
  • 78 countries ready to participate, Healthcare workers priority to be ready end of next year

 

Moderator:
Dr. William Chin, Professor of Medicine, Emeritus, Harvard Medical School

8-50 AM – 8-55 AM Break + Polling
8-55 AM – 9-10 AM India Regulatory update

Dr. Mandeep Bhandari, Joint Secretary, Ministry of Health & Family Welfare, India

  • COVID related – support for Clinical Trials support to the Industry, innovators, processes and infrastructure is in place

Dr. V G Somani, Drug Controller General of India, Central Drug Control Organization

  • partnership, time line, transparency
  • interaction online with regulators
  • 30 days approval pre and post approval – progress achieved
  • Online presubmission very useful to both sides
  • Ecosystems on early development: Gene therapy

Moderator:
Muna Bhanji, Senior Vice President,  Merck & Co.

  • India’s preparedness
9-10 AM – 9-15 AM Break + Polling
9-15 AM – 9-55 AM Fireside Chat

Kenneth Frazier, Chairman of the Board and Chief Executive Officer, Merck & Co.

Strategies of Merck = “Medicine is for the People not for Profit”

  • AntiViral – nucleocide – orally bioavailable
  • Vaccine in early development – BSV Vaccine used in EBOLA – attenuated virus vector platform experience – 1 single doze, deployed Globally
  • Vaccine modified Measles Vaccine, novel platform – out patient and Hospital
  • Antibiotic research at Merck – no market incentives on pricing for Merck to invest in antibiotics
  • people will die from bacterial resistance infection and next pandemic will be bacterial not viral

Moderator:
Dr. Stelios Papadopoulos, Chairman of the Board, Biogen

  • Most important comments on urgency in investment in drug development by multiple constituencies made by
  • Dr. George Yancopoulos, Co-Founder, President & CSO, Regeneron
  • Access to therapy
9-55 AM – 10 AM Break + Polling
10 AM – 10-40 AM India Innovation Landscape

Panelists:
Amitabh Kant, Chief Executive Officer, National Institution for Transforming India (NITI)

  • Innovation in drug discovery collaboration for clinical trial infrastructure
  • BioEconomy BioSimilar the largest number approved anywhere
  • Incentives for size and scale
  • Ingredients manufacturing to become India’s priority
  • Investment in R&D and Human Capital in the BioEconomy

Hari Bhartia, Founder & Co-Chairman, Jubilant Bhartia Group

  • US history of innovations cluster and infrastructure: Academe, VC, small medium Biopharma, Government involvement
  • India: Contract research – 20 years history, lagging the ability to take risk
  • Changing, pricing of drug increased, innovating drug for local consumption, and it can be taken to US for a better price
  • Cancer immunology in India under development
  • India was Leading Chemistry Research – China’s government invested and took the market
  • Indian companies bigger in size – free on requirement imposed on China
  • India will be a great supplier to US Market to build high capacity raw materials

Dr. K. Vijay Raghavan, Principal Scientific Advisor, Government of India

Resources are necessary 30% from Industry vs Government and Academe with great students and labs

Indian context – Personalized Medicine – Telemedicine and IT infrastructure allowing innovation in a 1Billion Population- sheer volume of quality professional

Dr. Naresh Trehan, Chairman, Medanta – the Medicity

  • Ecosystem ready for Government to promote innovations to conduct clinical trial with global acceptance standard
  • diverse gene pool in population to innovate for new molecule to market
  • Vaccine under development on Phase 1,2,3 – regulatory mechanism is in place
  • genetic drugs, BioSimilar dominance in the market – biotech can do clinical trials in India vs abroad

Moderator:
Sanat Chattopadhyay, President, Merck Manufacturing Division; Merck & Co.

  • Largest producer of generic drugs
  • antiretroviral drug produced by Indian Pharma
  • Biotech innovations growing middle class – how innovation , infrastructure and shift to research
  • Diversify and become self reliance
10-40 AM – 10-45 AM Break + Polling
10-45 AM – 11-25 AM Panel Discussion- Oncology: Changing landscape- COVID learnings and the promise of new technologies

Panelists:
Dr. Alise Reicin, Former President, Global Clinical Development, Celgene

  • Clinical trial were impacted by association of patients to trials
  • anti bacterial resistance requires investment – needs will be greater for antibiotics in the future
  • Cancer mutation next therapy biomarkers for mutations to be developed

Dr. Laurie Glimcher, President & CEO, Dana-Farber Cancer Institute

  • Dana Farber saw impact of COVID-19 on immunosuppressant population of patients coming in for Cancer Tx – switch from IV Tx to Oral
  • 96% decrease in screenings due to Pandemic – increase with Cancer diagnosis in coming years
  • No clinical Trials in Cancer were suspended – all continued
  • Telemedicine and working at home very efficient
  • Genomics of COVID-19 studies at Dana Farber same pathway identifies
  • safety and efficacy must be achieved – not to approve drugs without phase I & Phase II endpoints

Dr. Philip Larsen, Global Head of Research, Bayer AG

  • Repurposing drugs as antiviral from drug screening innovating methods
  • Cytokine storm in OCVID-19 – kinase inhibitors may be antiviral  – dat of tested positive allows research of pathway in new ways
  • Regulatory agencies in US and Europe for types of drugs vs single patient drugs

Rehan Verjee, President, EMD Serono

  • entire volume of clinical trials at Roche went down same at EMD
  • delay of 6 month, some were to be initiated but was put on hold
  • Charities funding cancer research – were impacted and resources will come later and in decreased amount
  • New opportunities support access to Medicine
  • improve investment across the board
  • Antibody cytotoxic with precision

Dr. Tony Ho, Head of Research and Development, CRISPR Therapeutics

  • challenges overcome by testing at home

Moderator:
Dr. Raju Kucherlapati, Professor of Genetics, Harvard Medical School

  • New normal as a result of the pandemic role of personalized medicine
  • Cancer cure – what are the prospects
11-25 AM – 11-30 AM Break + Polling
11-30 AM – 12-10 PM Panel Discussion- Industry & Investment Outlook

Panelists:
Christopher Viehbacher, Managing Partner, Gurnet Point Capital

  • IPOs can have advantages in Pandemics – Travel curtails all deals done virtually in greater efficiency
  • Drug pricing is a target by White house
  • Dream of every Biotech – get Big Pharma coming to acquire and pay a lot
  • Morph and adapt

Daphne Zohar, Founder & CEO, PureTech Health

  • kill project early financial incentive not in line in the industry
  • incentive to move resources among project and kill early project experiments to find which project to kill
  • Innovations – pattern recognition, fast followers academic translation
  • Disease focus, best science is the decision factors

Dr. Elias Zerhouni, Professor Emeritus, Johns Hopkins University

  • Digital Health
  • CVS opens clinics
  • R&D – Capital is low
  • Network of global innovation hubs vc investor channel like in the past
  • Value of company driven by hits blockbusters

 

Dr. Stelios Papadopoulos, Chairman, Biogen

  • Worst pandemic in our lifetime
  • stock market if hot – in balance in supply and demand, interest rates low, excess supply of equities in entertainment, Travel, hospitality
  • Healthcare was defensive therapeutics needed – opportunity to innovate in HC – shift money from entertainment, Travel hospitality to HC
  • Recovery will shift money away from Healthcare
  • IP Protection and patent expiration – biotech are cases not trends

Moderator:

Dr. Andrew Plump,

President of Research & Development, Takeda Pharmaceuticals

Moderator Presenter: Dr. Michael Rosenblatt, CEO

12-10 PM – 12-20 PM Break + Polling
12-20 PM – 1 PM Panel Discussion- Rare Diseases: No longer forgotten; but more to be achieved

ROI is not there, regulatory requirements reduced, Registry

Panelists:
Dr. Alfred Sandrock, Executive Vice President, Research & Development, Biogen

  • Multiple Sclerosis therapy
  • cost effectiveness is not there vs save a life
  • Appeal opportunity is there and regulators are people

Dr. Daniel Curran, Head of the Rare Diseases Therapeutic Area Unit, Takeda

  • Takeda collaborates with Grace Science Foundation

Dr. David Meeker, Chairman & CEO , Rhythm Pharmaceuticals

  • Cystic Fibrosis 

Dr. John Orloff, Head of Research & Development, Alexion

  • ALS
  • Duchenne Muscular Destrophy
  • HUS
  • ASO
  • gene therapy – one time therapy: Valuation for the industry of long term therapy: US (long term non existence) vs Europe and Japan (much appreciated

Matt Wilsey, Co-Founder & Chairman, Grace Science Foundation

  • Ultra-rare (500 Patients) vs Ultra Ultra-rare (50 Patients)
  • 70 patients in the World, Grace disease, Parent drive the search for drug
  • Manufacturing cost comes down
  • Price is dynamic

Moderator:
Dr. Steve Uden, Co-Founder, Rallybio

  • Regulators are people

 

1 PM – 1-05 PM Break + Polling
1-05 PM – 1-50 PM Fireside Chat

Dr. Roy Vagelos, Chairman of the Board, Regeneron Pharmaceuticals

  • Congratulate Big Pharma for taking the challenge on COVID-19
  • Vaccine, Antibody and anti-viral
  • Government funding
  • Merck was independent from Government – to be independent and be able to set the price
  • HIV-AIDS: reverse transcriptase converted a lethal disease to a chronic disease, tried hard to make vaccine – the science was not there
  • Industry role: Competition of drug discovery capacity is been built, global needs, price need be low for global reach
  • Government is a already a player hoping without a control on pricing
  • 300Million people were treated FREE by Merck’s Family Program HepC
  • 9% in China immunize the newborn with HepB 1994 100% babies immunized – no profit to Merck – eradication of HepB in China
  • Neuro degeneration – science supports drug development
  • Role of R&D Scientists in Drug discovery?

Moderator:
Dr. Mathai Mammen, Global Head of Janssen Research & Development, Johnson & Johnson

  • COVID-19 drug development: Response by Big Pharma
  • Industry role in Access to medicines, biologics, antibodies, vaccines
  • Role of R&D Scientists in Drug discovery?
  • PAHTN – use Machine Learning on top of data collected routinely,

 

1-50 PM – 1-55 PM Break + Polling
1-55 PM – 2-35 PM Panel Discussion- Digital & Data Science in Healthcare: Pragmatic Insights from the Real-World

Panelists:
Dr. Anne Heatherington, Head of Data Sciences Institute, Takeda Pharmaceuticals

  • Reliance on Data – AI and Data in Pharma alliance with MIT
  • collaboration of Data for COVID-19
  • Women need education in STEM and in Data Science

Arpa Garay, President, Global Pharmaceuticals, Commercial Analytics, Merck & Co.

  • Data on Patients and identification who will benefit fro which therapy
  •  cultural bias risk aversion
  • Invest early on in STEM

Dr. Maya Said, Chief Executive Officer, Outcomes4Me

  • Cancer patients taking change of their care
  • Digital Health – consumerization of Health, patient demand to be part of the decision, part of the information
  • FDA launched a Program Project Patient Voice

https://www.fda.gov/about-fda/oncology-center-excellence/project-patient-voice

  • Women should not undersell themselves

Dr. Najat Khan, Chief Operating Officer, Janssen R&D Data Sciences, Johnson & Johnson

  • Validation
  • Deployment of algorithms
  • embed data by type early on in the crisis to understand the disease
  • Compare the Big IT-Data and Pharma where are the barriers?
  • STEM and Women in Pharma – the opportunity must be right

Nina Kjellson, General Partner, Canaan

  • Data science is a winner in Healthcare
  • Women – Data Science is an excellent match

Moderator:
Sastry Chilukuri, President, Acorn AI- Medidata

  • Opportunities in Data Science in Pharma
  • COVID-19 and Data Science
  • STEM and Women in Pharma

 

2-35 PM – 2-40 PM Break + Polling
2-40 PM – 3-20 PM Panel Discussion- R&D Strategies and Trends: Innovation – The Big I

Panelists:
Dr. Andrew Plump, President of Research & Development, Takeda Pharmaceuticals

  • Enter for Plasma and for manufacturing vs discovery
  • Change how pharma behaved inefficiently in the past – with COVID-19 new behaviors in the industry
  • End of Century most diseases could be cured

Dr. David Reese, Executive Vice President, Research and Development, Amgen

  • Interaction with regulator was most favorable

Dr. Hal Barron, Chief Scientific Officer and President R&D, GlaxoSmithKline

  • Cytokine storm – few approaches
  • Control molecule GSK owned
  • GWAS not easy to find which gene drives the association
  • Functional Genomics gene by gene with phenotypes using machine learning significant help

Dr. Mathai Mammen, Global Head of Janssen Research & Development, Johnson & Johnson

  • Neuro-modulation: Symptomology Outcomes – no correlation
  • Vaccine platform used in the past for several vaccines: Selection process from several candidates, cell line enter Clinical waiting for data
  • Using same platform with several proteins – great communality in the development
  • Regulator deepen trust relationship which will carry for the future
  • Pulmonologists and cardiologist in the COVIS-19 Patients – remove drugs monitoring on drugs

Moderator:
Duval Patel presented the Moderator

Moderator:

Martin Mackay, Co-Founder, RallyBio

 

3-20 PM – 3-30 PM Closing Remarks

  • Every year it is getting better
  • India – innovate and make drugs for every country and for India
  • Diversity and inclusion
  • Leadership in Pharma Industry in all Panels
  • Massive impact can be made

 

Poll Questions for September 4

Polling Time (EST) Polling Topic
8-50 AM COVID-19 PanelQuestion 1: What do you foresee as the most likely outcome of the race to develop a vaccine?

  • Heightened international tensions due to inequities in distribution
  • Use of the vaccine as an instrument of geopolitics
  • Collaboration between governments to use vaccine to end the pandemic
  • All of the above

Question 2: What minimum criteria would you like to see for approval of COVID19 vaccines, assuming adequate efficacy?

  • Immune response in people over 60 years
  • Durability of response
  • Antibody plus T-cell response
  • Emergency Use Authorization with caveats followed by final approval
9-10 AM India Regulatory UpdateHow will MNCs respond to the recent regulatory changes for BioPharmas in India? They are _____ to run clinical trials there:

  • More likely
  • Less likely
  • Equally likely
9-55 AM Fireside Chat: Ken Frazier

The BioPharma industry this year has publicly committed itself to greater diversity. What specific measures do you expect to see?

  • Increasing diversity in clinical trials
  • Increasing diversity at the C-suite and board level
  • Increasing diversity throughout the company
  • All of the above
  • None of the above
10-40 AM India Innovation LandscapeWhat is the most important step India could take to become a global leader in life sciences innovation?”

  • Implement government policies to incentivize innovative drug development
  • Increase availability of financing for BioPharmas
  • Improve clinical trial infrastructure
  • Increase IP protection
11-25 AM Oncology PanelQuestion 1:

Changes in policy and reimbursement over the next five years will impact innovation in cancer therapeutics

  • Not at all
  • Slightly
  • Moderately
  • Significantly

Question 2: What therapeutic innovation do you think will have the biggest impact on cancer in the next five years?

  • Cell-based immunotherapies
  • Antibody-based immunotherapies
  • Bispecific / multi-specific antibodies
  • Antibody drug conjugates
12-10 PM Industry & Investment Outlook PanelMore and more funding has been going into preclinical companies — do you expect this trend to continue?

  • Yes
  • No

R&D Strategies and Trends Panel

COVID-19 has led to an unprecedented level of collaboration among stakeholders in the biopharma industry. Where do you expect to see the biggest increase in collaborations post-pandemic?

  • Discovery/preclinical research
  • Clinical development
  • Manufacturing
  • Commercialization
1 PM Rare Diseases PanelWhat is the biggest barrier to access to Orphan drugs in low-income countries?

  • Price, Access and Availability
  • Disease recognition and diagnosis
  • Lack of patient education regarding new therapies
  • Ultra-rarity of certain diseases creates barriers for BioPharma companies to pursue therapeutic
1-50 PM Fireside Chat: Roy VagelosQuestion 1:

Will pharma’s reputation continue its positive trend or return to negative base line beyond the pandemic

  • Yes
  • No

Question 2:

COVID-19 has put the spotlight on BioPharma as an essential player in the return to normalcy. What primary action do you think the industry needs to take to maintain a positive reputation beyond the pandemic?

  • Continue developing innovative drug pricing models
  • Increase drug pricing transparency
  • Increase data sharing and transparency
  • Improving availability and access in low income countries
2-35 PM Digital & Data Sciences PanelWhere has COVID-19 had the biggest impact on your adoption and use of digital health technologies?

  • Remote clinical trials and patient monitoring
  • Real-world data collection and analysis
  • Virtual drug launches

 

@@@@

In these unprecedented times due to COVID-19, USAIC is offering Free Registration for its annual summit.

Click for free registration

 

AGENDA & SPEAKERS

Chair and Master of Ceremonies (Emcee)– Dr. Andrew Plump, President of R&D, Takeda Pharmaceuticals
Summit Theme: “From N of One to N of a Billion”

  • Moderated Fireside Chat- Kenneth Frazier, Chairman of the Board and Chief Executive Officer, Merck & Co. and Stelios Papadopoulos, Chairman of the Board, Biogen
  • Moderated Fireside Chat- Roy Vagelos, Chairman of the Board, Regeneron Pharmaceuticals and Mathai Mammen, Global Head of R&D, Janssen Pharmaceutical Companies of Johnson & Johnson
  • Moderated Fireside Chat- K. VijayRaghavan, Principal Scientific Advisor, Government of India and Amitabh Kant, CEO, National Institution for Transforming India (NITI)

Panel Discussions:

  • Covid-19: Where are we now? Where are we going?
  • Oncology: A never ending tunnel?
  • Rare Diseases: Breaking Barriers for a Healthy Brain
  • Digital & Data Sciences: Leveraging data and digital to achieve healthcare solutions
  • Industry & Investment Outlook
  • R&D Strategies and Trends: Innovation – The Big I

Program and speakers subject to change*

14th Annual BioPharma & Healthcare Summit, Friday, September 4, 2020, 8 AM EST to 3-30 PM EST – Virtual Edition

Speakers


Kenneth Frazier
Chairman of the Board & CEO
Merck & Co.

Dr. Andrew Plump
President of R&D
Takeda Pharmaceuticals

Dr. Laurie Glimcher
President & CEO
Dana-Farber Cancer Institute

Dr. Roy Vagelos
Chairman of the Board
Regeneron

Dr. Stelios Papadopoulos
Chairman of the Board
Biogen

Christopher Viehbacher
Managing Partner
Gurnet Point Capital

Dr. Mathai Mammen
Global Head of R&D
Janssen- Johnson & Johnson

Kiran Mazumdar Shaw
Chairperson & Managing Director
Biocon

Dr. Hal Barron
President, R&D and CSO
GlaxoSmithKline

Prof. K. Vijay Raghavan
Principal Scientific Advisor
Government of India

Dr. George Yancopoulos
Co-Founder, President & CSO
Regeneron

Dr. Elias Zerhouni
Professor Emeritus
Johns Hopkins University

Daphne Zohar
Founder & CEO
PureTech Health

Sanat Chattopadhyay
President- Merck Manufacturing Division
Merck & Co.

Dr. David Reese
Executive Vice President- R&D
Amgen

Hari Bhartia
Founder & Co-Chairman
Jubilant Bhartia Group

Dr. Alfred Sandrock
Exe Vice President R&D & CMO
Biogen

Dr. Najat Khan
Chief Operating Officer, Data Sciences
Janssen- Johnson & Johnson

Dr. Richard Hatchett
Chief Executive Officer
CEPI

Amitabh Kant
Chief Executive Officer
NITI Aayog

Dr. Martin Mackay
Co-Founder
Rallybio

Dr. Daniel Curran
Head of the Rare Diseases TA
Takeda Pharmaceuticals

Dr. Alise Reicin
Former President, Global Clinical Dev.
Celgene

Dr. David Meeker
Chairman & CEO
Rhythm Pharmaceuticals

Dr. John Orloff
EVP and Head of R&D
Alexion

Dr. Barry Bloom
Professor & former Dean
Harvard School of Public Health

Dr. Mandeep Bhandari
Joint Secretary
Ministry of Health, India

Arpa Garay
President, Commercial Analytics
Merck & Co.

Dr. Steve Uden
Co-Founder
Rallybio

Dr. Philip Larsen
Global Head of Research
Bayer AG

Sastry Chilukuri
Executive Vice President
Medidata

Dr. William Chin
Professor of Medicine, Emeritus
Harvard Medical School

Dr. Anne Heatherington
Head of Data Sciences Institute
Takeda Pharmaceuticals

Dr. V G Somani
Drugs Controller General of India
Government of India

Dr. Rajeev Venkayya
President-Global Vaccines
Takeda

Dr. Raju Kucherlapati
Professor of Genetics
Harvard Medical School

Matt Wilsey
Co-Founder & Chairman
Grace Science Foundation

Muna Bhanji
SVP, Global Market Access
Merck & Co.

Dr. Maya Said
Chief Executive Officer
Outcomes4Me

Rehan Verjee
President
EMD Serono
Pharmasia News Biospectrum India Online

SOURCE:

https://usaindiachamber.org/speaker.php

Read Full Post »


Live Conference Coverage AACR 2020 in Real Time: Monday June 22, 2020 Mid Day Sessions

Reporter: Stephen J. Williams, PhD

This post will be UPDATED during the next two days with notes from recordings from other talks

Follow Live in Real Time using

#AACR20

@pharma_BI

@AACR

 

 

 

 

 

 

 

Register for FREE at https://www.aacr.org/

 

AACR VIRTUAL ANNUAL MEETING II

 

June 22-24: Free Registration for AACR Members, the Cancer Community, and the Public
This virtual meeting will feature more than 120 sessions and 4,000 e-posters, including sessions on cancer health disparities and the impact of COVID-19 on clinical trials

 

This Virtual Meeting is Part II of the AACR Annual Meeting.  Part I was held online in April and was centered only on clinical findings.  This Part II of the virtual meeting will contain all the Sessions and Abstracts pertaining to basic and translational cancer research as well as clinical trial findings.

 

REGISTER NOW

 

Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research

The prestigious Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research was established in 1997 to annually recognize a scientist of international renown who has made a major scientific discovery in basic cancer research OR who has made significant contributions to translational cancer research; who continues to be active in cancer research and has a record of recent, noteworthy publications; and whose ongoing work holds promise for continued substantive contributions to progress in the field of cancer. For more information regarding the 2020 award recipient go to aacr.org/awards.

John E. Dick, Enzo Galligioni, David A Tuveson

DETAILS

Awardee: John E. Dick
Princess Anne Margaret Cancer Center, Toronto, Ontario
For determining how stem cells contribute to normal and leukemic hematopoeisis
  • not every cancer cell equal in their Cancer Hallmarks
  • how do we monitor and measure clonal dynamics
  • Barnie Clarkson did pivotal work on this
  • most cancer cells are post mitotic but minor populations of cells were dormant and survive chemotherapy
  •  only one cell is 1 in a million can regenerate and transplantable in mice and experiments with flow cytometry resolved the question of potency and repopulation of only small percentage of cells and undergo long term clonal population
  • so instead of going to cell lines and using thousands of shRNA looked at clinical data and deconvoluted the genetic information (RNASeq data) to determine progenitor and mature populations (how much is stem and how much is mature populations)
  • in leukemic patients they have seen massive expansion of a single stem cell population so only need one cell in AML if the stem cells have the mutational hits early on in their development
  • finding the “seeds of relapse”: finding the small subpopulation of stem cells that will relapse
  • they looked in BALL;;  there are cells resistant to l-aspariginase, dexamethasone, and vincristine
  • a lot of OXPHOS related genes (in DRIs) that may be the genes involved in this resistance
  • it a wonderful note of acknowledgement he dedicated this award to all of his past and present trainees who were the ones, as he said, made this field into what it is and for taking it into directions none of them could forsee

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Experimental and Molecular Therapeutics, Drug Development, Cancer Chemistry

Chemistry to the Clinic: Part 1: Lead Optimization Case Studies in Cancer Drug Discovery

How can one continue to deliver innovative medicines to patients when biological targets are becoming ever scarcer and less amenable to therapeutic intervention? Are there sound strategies in place that can clear the path to targets previously considered “undruggable”? Recent advances in lead finding methods and novel technologies such as covalent screening and targeted protein degradation have enriched the toolbox at the disposal of drug discovery scientists to expand the druggable ta

Stefan N Gradl, Elena S Koltun, Scott D Edmondson, Matthew A. Marx, Joachim Rudolph

DETAILS

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Bioinformatics and Systems Biology, Molecular and Cellular Biology/Genetics

Informatics Technologies for Cancer Research

Cancer researchers are faced with a deluge of high-throughput data. Using these data to advance understanding of cancer biology and improve clinical outcomes increasingly requires effective use of computational and informatics tools. This session will introduce informatics resources that support the data management, analysis, visualization, and interpretation. The primary focus will be on high-throughput genomic data and imaging data. Participants will be introduced to fundamental concepts

Rachel Karchin, Daniel Marcus, Andriy Fedorov, Obi Lee Griffith

DETAILS

  • Variant analysis is the big bottleneck, especially interpretation of variants
  • CIVIC resource is a network for curation, interpretation of genetic variants
  • CIVIC curators go through multiple rounds of editors review
  • gene summaries, variant summaries
  • curation follows ACSME guidelines
  • evidences are accumulated, categories by various ontologies and is the heart of the reports
  • as this is a network of curators the knowledgebase expands
  • CIVIC is linked to multiple external informatic, clinical, and genetic databases
  • they have curated 7017 clinical interpretations, 2527 variants, using 2578 papers, and over 1000 curators
  • they are currently integrating with COSMIC ClinVar, and UniProt
  • they are partnering with ClinGen to expand network of curators and their curation effort
  • CIVIC uses a Python interface; available on website

https://civicdb.org/home

The Precision Medicine Revolution

Precision medicine refers to the use of prevention and treatment strategies that are tailored to the unique features of each individual and their disease. In the context of cancer this might involve the identification of specific mutations shown to predict response to a targeted therapy. The biomedical literature describing these associations is large and growing rapidly. Currently these interpretations exist largely in private or encumbered databases resulting in extensive repetition of effort.

CIViC’s Role in Precision Medicine

Realizing precision medicine will require this information to be centralized, debated and interpreted for application in the clinic. CIViC is an open access, open source, community-driven web resource for Clinical Interpretation of Variants in Cancer. Our goal is to enable precision medicine by providing an educational forum for dissemination of knowledge and active discussion of the clinical significance of cancer genome alterations. For more details refer to the 2017 CIViC publication in Nature Genetics.

U24 funding announced: We are excited to announce that the Informatics Technology for Cancer Research (ICTR) program of the National Cancer Institute (NCI) has awarded funding to the CIViC team! Starting this year, a five-year, $3.7 million U24 award (CA237719), will support CIViC to develop Standardized and Genome-Wide Clinical Interpretation of Complex Genotypes for Cancer Precision Medicine.

Informatics tools for high-throughput analysis of cancer mutations

Rachel Karchin
  • CRAVAT is a platform to determine, categorize, and curate cancer mutations and cancer related variants
  • adding new tools used to be hard but having an open architecture allows for modular growth and easy integration of other tools
  • so they are actively making an open network using social media

Towards FAIR data in cancer imaging research

Andriy Fedorov, PhD

Towards the FAIR principles

While LOD has had some uptake across the web, the number of databases using this protocol compared to the other technologies is still modest. But whether or not we use LOD, we do need to ensure that databases are designed specifically for the web and for reuse by humans and machines. To provide guidance for creating such databases independent of the technology used, the FAIR principles were issued through FORCE11: the Future of Research Communications and e-Scholarship. The FAIR principles put forth characteristics that contemporary data resources, tools, vocabularies and infrastructures should exhibit to assist discovery and reuse by third-parties through the web. Wilkinson et al.,2016. FAIR stands for: Findable, Accessible, Interoperable and Re-usable. The definition of FAIR is provided in Table 1:

Number Principle
F Findable
F1 (meta)data are assigned a globally unique and persistent identifier
F2 data are described with rich metadata
F3 metadata clearly and explicitly include the identifier of the data it describes
F4 (meta)data are registered or indexed in a searchable resource
A Accessible
A1 (meta)data are retrievable by their identifier using a standardized communications protocol
A1.1 the protocol is open, free, and universally implementable
A1.2 the protocol allows for an authentication and authorization procedure, where necessary
A2 metadata are accessible, even when the data are no longer available
I Interoperable
I1 (meta)data use a formal, accessible, shared, and broadly applicable language for knowledge representation.
I2 (meta)data use vocabularies that follow FAIR principles
I3 (meta)data include qualified references to other (meta)data
R Reusable
R1 meta(data) are richly described with a plurality of accurate and relevant attributes
R1.1 (meta)data are released with a clear and accessible data usage license
R1.2 (meta)data are associated with detailed provenance
R1.3 (meta)data meet domain-relevant community standards

A detailed explanation of each of these is included in the Wilkinson et al., 2016 article, and the Dutch Techcenter for Life Sciences has a set of excellent tutorials, so we won’t go into too much detail here.

  • for outside vendors to access their data, vendors would need a signed Material Transfer Agreement but NCI had formulated a framework to facilitate sharing of data using a DIACOM standard for imaging data

Monday, June 22

1:30 PM – 3:01 PM EDT

Virtual Educational Session

Experimental and Molecular Therapeutics, Cancer Chemistry, Drug Development, Immunology

Engineering and Physical Sciences Approaches in Cancer Research, Diagnosis, and Therapy

The engineering and physical science disciplines have been increasingly involved in the development of new approaches to investigate, diagnose, and treat cancer. This session will address many of these efforts, including therapeutic methods such as improvements in drug delivery/targeting, new drugs and devices to effect immunomodulation and to synergize with immunotherapies, and intraoperative probes to improve surgical interventions. Imaging technologies and probes, sensors, and bioma

Claudia Fischbach, Ronit Satchi-Fainaro, Daniel A Heller

DETAILS

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Survivorship

Exceptional Responders and Long-Term Survivors

How should we think about exceptional and super responders to cancer therapy? What biologic insights might ensue from considering these cases? What are ways in which considering super responders may lead to misleading conclusions? What are the pros and cons of the quest to locate exceptional and super responders?

Alice P Chen, Vinay K Prasad, Celeste Leigh Pearce

DETAILS

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Tumor Biology, Immunology

Exploiting Metabolic Vulnerabilities in Cancer

The reprogramming of cellular metabolism is a hallmark feature observed across cancers. Contemporary research in this area has led to the discovery of tumor-specific metabolic mechanisms and illustrated ways that these can serve as selective, exploitable vulnerabilities. In this session, four international experts in tumor metabolism will discuss new findings concerning the rewiring of metabolic programs in cancer that support metabolic fitness, biosynthesis, redox balance, and the reg

Costas Andreas Lyssiotis, Gina M DeNicola, Ayelet Erez, Oliver Maddocks

DETAILS

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Other Articles on this Open Access  Online Journal on Cancer Conferences and Conference Coverage in Real Time Include

Press Coverage

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Symposium: New Drugs on the Horizon Part 3 12:30-1:25 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on NCI Activities: COVID-19 and Cancer Research 5:20 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on Evaluating Cancer Genomics from Normal Tissues Through Metastatic Disease 3:50 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on Novel Targets and Therapies 2:35 PM

Read Full Post »


Live Conference Coverage AACR 2020 in Real Time: Monday June 22, 2020 8AM-Noon Sessions

Reporter: Stephen J. Williams, PhD

Follow Live in Real Time using

#AACR20

@pharma_BI

@AACR

 

Register for FREE at https://www.aacr.org/

AACR VIRTUAL ANNUAL MEETING II

 

June 22-24: Free Registration for AACR Members, the Cancer Community, and the Public
This virtual meeting will feature more than 120 sessions and 4,000 e-posters, including sessions on cancer health disparities and the impact of COVID-19 on clinical trials

 

This Virtual Meeting is Part II of the AACR Annual Meeting.  Part I was held online in April and was centered only on clinical findings.  This Part II of the virtual meeting will contain all the Sessions and Abstracts pertaining to basic and translational cancer research as well as clinical trial findings.

 

REGISTER NOW

 

Monday, June 22

8:30 AM – 10:10 AM EDT

Virtual Special Session

Opening Ceremony

The Opening Ceremony will include the following presentations:
Welcome from AACR CEO Margaret Foti, PhD, MD (hc)

CHIEF EXECUTIVE OFFICER

MARGARET FOTI, PHD, MD (HC)

​American Association for Cancer Research
Philadelphia, Pennsylvania

  • Dr. Foti mentions that AACR is making progress in including more ethnic and gender equality in cancer research and she feels that the disparities seen in health care, and in cancer care, is related to the disparities seen in the cancer research profession
  • AACR is very focused now on blood cancers and creating innovation summits on this matter
  • In 2019 awarded over 60 grants but feel they will be able to fund more research in 2020
  • Government funding is insufficient at current levels

Remarks from AACR Immediate Past President Elaine R. Mardis, PhD, FAACR

  • involved in planning and success of the first virtual meeting (it was really well done)
  • # of registrants was at unprecedented numbers
  • the scope for this meeting will be wider than the first meeting
  • they have included special sessions including COVID19 and health disparities
  • 70 educational and methodology workshops on over 70 channels

AACR Award for Lifetime Achievement in Cancer Research

  • Dr. Philip Sharp is awardee of Lifetime Achievement Award
  • Dr. Sharp is known for his work in RNA splicing and development of multiple cancer models including a mouse CRSPR model
  • worked under Jim Watson at Cold Spring Harbor
    Presentation of New Fellows of the AACR Academy
  • Dr. Radcliffe for hypoxic factors
  • CART therapies
  • Dr. Semenza for HIF1 discovery
  • Dr Swanton for stratification of patients and tumor heterogeneity
  • these are just some of the new fellows

AACR-Biedler Prizes for Cancer Journalism

  • Writer of Article War of Nerves awarded; reported on nerve intervation of tumors
  • writer Budman on reporting and curation of hedgehog inhibitors in cancers
  • patient advocacy book was awarded for journalism
  • cancer survivor Kasie Newsome produced multiple segments on personalized cancer therapy from a cancer survivor perspective

Remarks from Speaker of the United States House of Representatives Nancy Pelosi

  • helped secure a doubling of funding for NCI and NIH in the 90s
  • securing COVID funding to offset some of the productivity issues related to the shutdown due to COVID
  • advocating for more work to alleviate health disparities

 

Remarks from United States Senator Roy Blunt

  • tireless champion in the Senate for cancer research funding; he was a cancer survivor himself
  • we need to keep focus on advances in science

Margaret Foti

DETAILS

Monday, June 22

10:10 AM – 12:30 PM EDT

Virtual Plenary Session

Bioinformatics and Systems Biology, Epidemiology, Immunology, Molecular and Cellular Biology/Genetics

Opening Plenary Session: Turning Science into Lifesaving Care

Alexander Marson, Antoni Ribas, Ashani T Weeraratna, Olivier Elemento, Howard Y Chang, Daniel D. De Carvalho

DETAILS

Monday, June 22

12:45 PM – 1:30 PM EDT

Awards and Lectures

How should we think about exceptional and super responders to cancer therapy? What biologic insights might ensue from considering these cases? What are ways in which considering super responders may lead to misleading conclusions? What are the pros and cons of the quest to locate exceptional and super responders?

Alice P Chen, Vinay K Prasad, Celeste Leigh Pearce

DETAILS

Monday, June 22

1:30 PM – 3:30 PM EDT

Virtual Educational Session

Tumor Biology, Immunology

Experimental and Molecular Therapeutics, Immunology

Other Articles on this Open Access  Online Journal on Cancer Conferences and Conference Coverage in Real Time Include

Press Coverage

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Symposium: New Drugs on the Horizon Part 3 12:30-1:25 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on NCI Activities: COVID-19 and Cancer Research 5:20 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on Evaluating Cancer Genomics from Normal Tissues Through Metastatic Disease 3:50 PM

Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on Novel Targets and Therapies 2:35 PM

 

Read Full Post »


 

custom image

Vaccinology in the Age of Pandemics:
Strategies Against COVID-19 & Other Global Threats

June 15–16, 2020 | 11:00AM–3:30PM ET | 3:00–7:30PM UTC | 5:00–9:30PM CEST*
*Program is subject to change


As the world faces the greatest global pandemic of our lifetimes, the critical importance of vaccine development has come to the forefront of scientific and public audiences alike. Over the course of history, vaccination has enabled us to conquer devastating diseases from measles to smallpox, but new challenges arise when addressing an emerging pandemic in real time. This virtual meeting will assemble the world’s leading vaccinology and global health experts to present the latest advances in vaccine design and development. Finally, this virtual conference will discuss how to best apply these strategies in the context of the current pandemic.

The field of vaccinology has made great leaps in recent years, providing novel technologies and approaches that can be leveraged to our advantage against the novel coronavirus, COVID-19. Incredible advances in science and technology now make it technically possible to develop vaccines against many new targets. Meanwhile, innovative approaches to vaccine development are tackling challenges of emerging infections and implementation in low-income countries. These advances, among many others, will guide the way towards a safe and effective COVID-19 vaccine. Additionally, these new scientific advances will set the stage for success against this pandemic, as vaccinologists race against the ever-rising global death toll.

This virtual meeting program will cover many important facets of vaccine science, technology and strategy, including:

  • transformative new technologies, including structure-based design, adjuvants, nucleic acid vaccines (especially RNA), viral vectors, systems biology, and controlled human infections
  • scientific underpinnings of new vaccinology strategies, including advances in the fields of human immunology, genomics, synthetic biology, molecular structure of antigens and antigen-antibody complexes, germinal centers, and microbiome
  • multidisciplinary technologies and strategies, including efforts of Coalition for Epidemic Preparedness Innovations (CEPI), Bill & Melinda Gates Foundation and Wellcome Trust, which will change the way vaccines are developed

Program is intended for scientific researchers and clinical audiences.

Join us for this landmark virtual event, brought to you by Keystone Symposia.

Regular Registration Rate: $50 USD

#VKSvaxcovid19

SPEAKERS

Program Details

Keynote Speaker


Anthony S. Fauci, MD
Anthony S. Fauci, MD
NIAID, National Institutes of Health
Transforming Vaccinology: Considerations for the Next Decade

Speaking at this eSymposia


Galit Alter

MIT and Harvard University

Yasmine Belkaid

NIAID, National Institutes of Health

Anthony S. Fauci, MD

Anthony S. Fauci

NIAID, National Institutes of Health

Barney S. Graham

NIAID, National Institutes of Health

Richard Hatchett

Coalition for Epidemic Preparedness Innovations, CEPI

Neil P. King

University of Washington

Antonio Lanzavecchia

Institute for Research in Biomedicine

Ulrike Protzer

Technische Universität München

Bali Pulendran

Stanford University School of Medicine

Rino Rappuoli

GlaxoSmithKline Vaccines

Federica Sallusto

Università della Svizzera Italiana & ETH Zurich

Robert A. Seder

NIAID, National Institutes of Health

Christine Shaw

Moderna

Gabriel D. Victora

Gabriel D. Victora

Rockefeller University

Hedda Wardemann

German Cancer Research Center

Catherine J. Wu

Dana-Farber Cancer Institute

SOURCE

Read Full Post »


2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

Dialogue among principals is a World Forum’s signature. Expert moderators guiding discussion and questions in audience friendly exchanges. No slides – shared perspectives facilitated by Harvard faculty, leading journalists and Mass General Brigham executives.

Jeffrey Golden, MD

Chair, Department of Pathology, BH; Ramzi S. Cotran Professor of Pathology, Harvard Medical School

Hadine Joffe, MD

Vice Chair, Psychiatry, Executive Director, Mary Horrigan Connors Center for Women’s Health and Gender Biology, BH; Paula A. Johnson Professor, Women’s Health, Harvard Medical School

Thomas Sequist, MD

Chief Patient Experience and Equity Officer, Mass General Brigham; Professor of Medicine and Health Care Policy, Harvard Medical School

Erica Shenoy, MD, PhD

Associate Chief, Infection Control Unit, MGH; Assistant Professor, Harvard Medical School

Gregg Meyer, MD

Chief Clinical Officer, Mass General Brigham; Interim President, NWH; Professor, Harvard Medical School

Ravi Thadhani, MD

CAO, Mass General Brigham; Professor and Faculty Dean for Academic Programs, Harvard Medical School

Ann Prestipino

SVP; Incident Commander, MGH

Roger Kitterman

VP, Venture and Managing Partner, Partners Innovation Fund, Mass General Brigham

David Louis, MD

Pathologist-in-Chief, MGH; Benjamin Castleman Professor of Pathology, Harvard Medical School

Janet Wu

Bloomberg

Ron Walls, MD

EVP and Chief Operating Officer, BH; Neskey Family Professor of Emergency Medicine, Harvard Medical School

Alice Park

Senior Writer, TIME

 

Jeffrey Golden, MD

Chair, Department of Pathology, BH; Ramzi S. Cotran Professor of Pathology, Harvard Medical School

Hadine Joffe, MD

Vice Chair, Psychiatry, Executive Director, Mary Horrigan Connors Center for Women’s Health and Gender Biology, BH; Paula A. Johnson Professor, Women’s Health, Harvard Medical School

Thomas Sequist, MD

Chief Patient Experience and Equity Officer, Mass General Brigham; Professor of Medicine and Health Care Policy, Harvard Medical School

Erica Shenoy, MD, PhD

Associate Chief, Infection Control Unit, MGH; Assistant Professor, Harvard Medical School

Gregg Meyer, MD

Chief Clinical Officer, Mass General Brigham; Interim President, NWH; Professor, Harvard Medical School

Ravi Thadhani, MD

CAO, Mass General Brigham; Professor and Faculty Dean for Academic Programs, Harvard Medical School

Ann Prestipino

SVP; Incident Commander, MGH

Roger Kitterman

VP, Venture and Managing Partner, Partners Innovation Fund, Mass General Brigham

David Louis, MD

Pathologist-in-Chief, MGH; Benjamin Castleman Professor of Pathology, Harvard Medical School

Janet Wu

Bloomberg

Ron Walls, MD

EVP and Chief Operating Officer, BH; Neskey Family Professor of Emergency Medicine, Harvard Medical School

Alice Park

Senior Writer, TIME

 

VIEW VIDEOS from the event

https://www.youtube.com/channel/UCauKpbsS_hUqQaPp8EVGYOg

 

From: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Date: Tuesday, May 12, 2020 at 6:48 AM

To: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Subject: REGISTRANT RECAP | World Medical Innovation Forum  

 

Dear World Forum Attendee, 

On behalf of Mass General Brigham CEO Anne Klibanski MD and Forum co-Chairs Gregg Meyer MD and Ravi Thadhani MD, many thanks for being among the nearly 11,000 registrants representing 93 countries, 46 states and 3200 organizations yesterday. A community was established around many pressing topics that  will continue long into the future. We hope you have a chance to examine the attached survey results. There are several revealing items that should be the basis for ongoing discussion. We expect to be in touch regularly during the year. Among the plans is a “First Look” video series highlighting top Mass General Brigham Harvard faculty as well as emerging Harvard investigators.  As promised, we  wanted to also share visual Forum session summaries.  You will be able to access the recordings on the Forum’s YouTube page . The first set will go up this morning

We hope you will join us for the 2021 Forum!  

Thanks again, Chris

e-Proceedings 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/04/22/world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-monday-may-11-815-a-m-515-p-m-et/

Tweets & Retweets 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/05/11/tweets-retweets-2020-world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-mond/

Read Full Post »


Collaborative innovation has never been more important.

2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

Join top leaders guiding the response, technology and people confronting this century’s greatest health challenge.

Priya Abani

CEO, AliveCor

General Keith Alexander

Co-CEO, IronNet; Former NSA Head

Stéphane Bancel

CEO, Moderna

Marc Casper

CEO, Thermo Fisher

Timothy Ferris, MD

CEO, MGPO; Professor, HMS

John Fernandez  

President, MEE; President, Ambulatory Care, Mass General Brigham

 

John Fish

CEO, Suffolk; BH Board Chair

JF Formela, MD

Partner, Atlas Venture

Jan Garfinkle

Manager Partner, Arboretum Ventures; Chair, NVCA

Phillip Gross

Managing Director, Adage Capital Management

Julia Hu

CEO, Lark Health

Anjali Kataria

CEO, Mytonomy

Roger Kitterman

VP, Managing Partner, Mass General Brigahm Fund

Jonathan Kraft

President, Kraft Group; Chair, MGH Board

Brooke LeVasseur

CEO, AristaMD

Mike Mahoney

CEO, Boston Scientific

Bernd Montag, PhD

CEO, Siemens Healthineers

Kieran Murphy

CEO, GE Healthcare

Elizabeth Nabel, MD

President, BH; Professor, HMS

Matt Sause

CEO, Roche Diagnostics

Peter Slavin, MD

President, MGH; Professor, HMS

Scott Sperling

Co-President, TH Lee; Chair, Mass General Brigham Board

Christopher Viehbacher

Managing Partner, Gurnet Point Capital

Michel Vounatsos

CEO, Biogen

Collaborative Innovation

Together we meet the challenge of the coronavirus and share our commitment to the future of medicine.

 

Anne Klibanski, MD

CEO, Mass General Brigham

Amy Abernethy, MD, PhD

Principal Deputy Commissioner and Acting CIO, FDA

PANEL

FDA Role in Managing Crisis and Anticipating the Next

Elizabeth Nabel, MD

President, Brigham Health; Professor of Medicine, HMS

PANEL

Care in the Next 18 Months 

Karen DeSalvo, MD

Chief Health Officer, Google Health

PANEL

Role of AI and Big Data in Fighting COVID-19 

Dawn Sugarman, PhD

Assistant Psychologist, Division of Alcohol, Drugs, and Addiction, McLean; Assistant Professor, Psychiatry, HMS

PANEL

Digital Therapeutics

Ann Prestipino

SVP; Incident Commander, MGH; Teaching Associate, HMS

PANEL

Real Time: Front Line Innovation

Hadine Joffe, MD

Vice Chair, Research, Psychiatry; Executive Director, Mary Horrigan Connors Center for Women’s Health and Gender Biology, BH; Paula Johnson Professor, Women’s Health, HMS

PANEL

Digital Therapeutics

Priya Abani

CEO, AliveCor

PANEL

Digital Therapeutics

Julia Hu

CEO, Lark Health

PANEL

Digital Therapeutics

Jan Garfinkle

Manager Partner, Arboretum Ventures; Chair NVCA

PANEL

Early Stage Investment Environment

Anjali Kataria

CEO, Mytonomy

PANEL

Patient Experience During the Pandemic

Brooke LeVasseur

CEO, AristaMD

PANEL

Digital Health Becomes a Pillar

Julie Lankiewicz

Head, Clinical Affairs & Health Economics Outcomes Research, Bose Health

PANEL

Emergency and Urgent Care

 

VIEW VIDEOS from the event

https://www.youtube.com/channel/UCauKpbsS_hUqQaPp8EVGYOg

 

From: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Date: Tuesday, May 12, 2020 at 6:48 AM

To: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Subject: REGISTRANT RECAP | World Medical Innovation Forum  

 

Dear World Forum Attendee, 

On behalf of Mass General Brigham CEO Anne Klibanski MD and Forum co-Chairs Gregg Meyer MD and Ravi Thadhani MD, many thanks for being among the nearly 11,000 registrants representing 93 countries, 46 states and 3200 organizations yesterday. A community was established around many pressing topics that  will continue long into the future. We hope you have a chance to examine the attached survey results. There are several revealing items that should be the basis for ongoing discussion. We expect to be in touch regularly during the year. Among the plans is a “First Look” video series highlighting top Mass General Brigham Harvard faculty as well as emerging Harvard investigators.  As promised, we  wanted to also share visual Forum session summaries.  You will be able to access the recordings on the Forum’s YouTube page . The first set will go up this morning

We hope you will join us for the 2021 Forum!  

Thanks again, Chris

e-Proceedings 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/04/22/world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-monday-may-11-815-a-m-515-p-m-et/

Tweets & Retweets 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/05/11/tweets-retweets-2020-world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-mond/

Read Full Post »


2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

 

Thermo Fisher provides the technologies required to return to work as well as to combat a COVID-19 resurgence. CEO Marc Casper shares perspectives with MGB EVP Peter Markell.

Marc Casper

CEO, Thermo Fisher

Moderator

Peter Markell

EVP and CFO,

Mass General Brigham

 

VIEW VIDEOS from the event

https://www.youtube.com/channel/UCauKpbsS_hUqQaPp8EVGYOg

 

From: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Date: Tuesday, May 12, 2020 at 6:48 AM

To: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Subject: REGISTRANT RECAP | World Medical Innovation Forum  

 

Dear World Forum Attendee, 

On behalf of Mass General Brigham CEO Anne Klibanski MD and Forum co-Chairs Gregg Meyer MD and Ravi Thadhani MD, many thanks for being among the nearly 11,000 registrants representing 93 countries, 46 states and 3200 organizations yesterday. A community was established around many pressing topics that  will continue long into the future. We hope you have a chance to examine the attached survey results. There are several revealing items that should be the basis for ongoing discussion. We expect to be in touch regularly during the year. Among the plans is a “First Look” video series highlighting top Mass General Brigham Harvard faculty as well as emerging Harvard investigators.  As promised, we  wanted to also share visual Forum session summaries.  You will be able to access the recordings on the Forum’s YouTube page . The first set will go up this morning

We hope you will join us for the 2021 Forum!  

Thanks again, Chris

e-Proceedings 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/04/22/world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-monday-may-11-815-a-m-515-p-m-et/

Tweets & Retweets 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/05/11/tweets-retweets-2020-world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-mond/

Read Full Post »


2020 World Medical Innovation Forum – COVID-19, AI  – Life Science and Digital Health Investments, MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

 

 

 

Life science and digital health investments have continued at a strong pace during the COVID-19 crisis. Senior investment leaders discuss what to expect. Will:

  • social distancing affect deal making?
  • key asset categories remain strong – venture, private equity, public offerings, acquisitions?
  • valuations hold up in some categories while others fall?

Moderator: Roger Kitterman, VP, Venture and Managing Partner, Partners Innovation Fund, Mass General Brigham


Jan Garfinkle
, Founder & Manager Partner, Arboretum Ventures, Chair NVCA

Phillip Gross, Managing Director, Adage Capital Management

Christopher Viehbacher, Managing Partner, Gurnet Point Capital

 

VIEW VIDEOS from the event

https://www.youtube.com/channel/UCauKpbsS_hUqQaPp8EVGYOg

From: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Date: Tuesday, May 12, 2020 at 6:48 AM

To: “Coburn, Christopher Mark” <CMCOBURN@PARTNERS.ORG>

Subject: REGISTRANT RECAP | World Medical Innovation Forum  

 

Dear World Forum Attendee, 

On behalf of Mass General Brigham CEO Anne Klibanski MD and Forum co-Chairs Gregg Meyer MD and Ravi Thadhani MD, many thanks for being among the nearly 11,000 registrants representing 93 countries, 46 states and 3200 organizations yesterday. A community was established around many pressing topics that  will continue long into the future. We hope you have a chance to examine the attached survey results. There are several revealing items that should be the basis for ongoing discussion. We expect to be in touch regularly during the year. Among the plans is a “First Look” video series highlighting top Mass General Brigham Harvard faculty as well as emerging Harvard investigators.  As promised, we  wanted to also share visual Forum session summaries.  You will be able to access the recordings on the Forum’s YouTube page . The first set will go up this morning

We hope you will join us for the 2021 Forum!  

Thanks again, Chris

e-Proceedings 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/04/22/world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-monday-may-11-815-a-m-515-p-m-et/

Tweets & Retweets 2020 World Medical Innovation Forum – COVID-19, AI and the Future of Medicine, Featuring Harvard and Industry Leader Insights – MGH & BWH, Virtual Event: Monday, May 11, 8:15 a.m. – 5:15 p.m. ET

https://pharmaceuticalintelligence.com/2020/05/11/tweets-retweets-2020-world-medical-innovation-forum-covid-19-ai-and-the-future-of-medicine-featuring-harvard-and-industry-leader-insights-mgh-bwh-virtual-event-mond/

Read Full Post »

Older Posts »