e-VOICES Podcasting
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Podcast with Dr. Sudipta Saha, PhD, Interview by Gail S. Thornton, PhDc, Narrator’s Voice: Gail S. Thornton, PhDc
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Podcast with Dr. Larry H. Bernstein, MD, FCAP, Interview by Gail S. Thornton, PhDc, Narrator’s Voice: Stephen J. Williams, PhD
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Podcast with Prof. Marcus W. Feldman, PhD, Biology Department, Stanford University, Interview by Gail S. Thornton, PhDc
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Partners in Health and Biz Radio Interview with Aviva Lev-Ari, Ph.D., R.N., Stephen Williams, Ph.D., and Irina Robu, Ph.D., on 5/2019 on topic of 3D Medical BioPrinting Technology: A Revolution in Medicine. Interview organizer: Gail S. Thornton, PhDc
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Standard Operating Procedures for Text to Audio Conversion – How to Create a Podcast and Embed it on a Post or on a Page
Development Plan for e-VOICES Podcasting, 2019 – 2021*
https://pharmaceuticalintelligence.com/audio-podcasts/
Updated on 1/9/2021
Podcast Interviewer | INTERVIEWEE(S) | Subject | Date |
Audio/Video/ Narrator |
Gail S. Thornton | Dr. Stephen J. Williams, Dr. Irina Robu & Dr. Aviva Lev-Ari | 3D BioPrinting in Medicine | 5/2019 | Audio |
Gail S. Thornton | Prof. Feldman | Evolution Biology and Population Genetics | 3/17/2020 | Audio |
Gail S. Thornton | Dr. Larry H. Bernstein, MD, FCAP | Life Memoirs in Clinical Pathology Told | 10/12/2020 | Audio
Narrator: Dr. S.J. Williams |
Gail S. Thornton | Dr. Sudipta Saha | Research in Reproductive Technology | 12/31/2020 | Audio |
Gail S. Thornton | Dr. Justin D. Pearlman, MD, PhD | Cardiac Imaging – Evolution of Diagnostic Methods | 1Q 2021 | Audio |
Gail S. Thornton | Dr. Raphael Nir | From Big Pharma to Biotech Entrepreneurship | 2021 | Audio |
Gail S. Thornton | Dr. Meg Baker | GlycoBiology in Practice | 2021 | Audio |
Gail S. Thornton | Dr. Ofer Markman | Memories of
Procognia |
2021 | Audio |
Gail S. Thornton | Dr. Irina Robu | AI & Tissue Engineering | 2021 | Audio |
Gail S. Thornton | Dr. Williams | Preferably 3rd party interviewer sourced AI & Genomics by Gail | 2021 | Audio |
Gail S. Thornton | Dr. Aviva Lev-Ari | Preferably 3rd party interviewer sourced Curation & ML by Gail | 2021 | Audio |
12/31/2020
Interview with Dr. Sudipta Saha, Assistant Professor in Physiology at Amity University, Noida, India by Gail S. Thornton
Reporter: Gail S. Thornton, M.A.
Welcome to E-Voices, our podcast series exploring cutting-edge science and medical topics, sponsored by the Leaders in Pharmaceutical Business Intelligence. I’m Gail Thornton, your host for this podcast.
Today’s guest is Dr. Sudipta Saha, Ph.D., who is an Assistant Professor in Physiology at Amity University in Noida, India, since 2017.
Dr. Saha completed his Ph.D. in Reproductive Biology from CSIR-Indian Institute of Chemical Biology in 2008 under the supervision of Dr. G.C. Majumder. He began his postdoctoral research in the same lab and later moved to Taiwan to work as a postdoctoral researcher at Chang Gung Memorial Hospital with Dr. Yu Cheng Pei and, subsequently, at Chang Gung University with Prof. Pin Ouyang. He later returned to India and was granted a Senior Research Associate Fellowship from the Council of Scientific and Industrial Research (CSIR), working as a Scientists’ Pool Officer during 2015 through 2017 at the same Institute where he did his Ph.D.
During his first postdoctoral tenure in Taiwan with Dr. Yu Cheng Pei, he had the opportunity to visit and receive training at the lab of Dr. Sliman Bensmaia at University of Chicago in the United States. During his postdoctoral research in Taiwan, he was part of a team that made an instrument that can analyze visual and tactile motion integration in the somatosensory cortex of the brain. This research was published in the journal Sensors.
In his second postdoctoral tenure in Taiwan he worked on regulation of cell division. More specifically, his work was on localization of Cep55 and FLJ25439 proteins during cytokinesis. A part of the research was published in the journal Cell Cycle. Cep55 knockout mice also were developed in the same lab and maintained by him to find some interesting phenotypes.
During his Ph.D. research, he created a novel spectrophotometer-based instrument system to determine and analyze the vertical movement of spermatozoa, including vertical velocity. Vertical velocity is a better index of sperm health as it is recorded against the gravity. This research occurred with the help through an industrial collaboration, which then led to a patent granted in India and data published later in the journal of quantitative cell science, Cytometry Part A.
Additionally, Dr. Saha isolated a novel protein from goat blood that can enhance the sperm forward motility to a great extent and much more than any other known motility promoters like theophylline or bicarbonate. This protein also helped in maintaining sperm motility in room temperature for a long duration. The antibody of this protein also inhibited sperm-egg interaction. This research was published in Fertility and Sterility.
Both Dr. Saha’s Ph.D. research topics have potential use in fertility management and conservation of endangered species. The instrument design brought several awards, including two best poster awards, the India Innovation Pioneers Challenge Award from Indo-U.S. Science and Technology Forum and the Biotech Idea to Innovation Award from the British Council. Because of these recognitions, he received additional training at the lab of Dr. Uday Kishore in Brunel University, London, U.K.
For the past eight years, he has been an author, curator and reporter of numerous scientific articles for Leaders in Pharmaceutical Business Intelligence (LPBI) Group, a pharmaceutical media venture with several cloud-based products. LPBI Group’s products include an open-access online scientific journal called PharmaceuticalIntelligence.com, a BioMed e-Series of 16 volumes in Medicine, real-time press coverage of biotech and medical conferences, and a podcast library of Interviews with key opinion leaders, all involving a team of experts, authors and writers in science and medicine.
Dr. Saha served as an Editor on several volumes in LPBI’s BioMed e-Series, namely on gene editing, genomics, cardiovascular disease and regenerative and translational medicine. He has published 14 journal articles, four book chapters and eight e-Books.
He is one of six authors of a recently published book (In Press), Microbial Pathogenesis: Infection and Immunity, by Springer Nature in New York. In this book, he co-authored a chapter on the COVID-19 pandemic with Dr. Uday Kishore. The title of the chapter is: SARS-CoV-2: Pathogenic mechanisms and host immune response.
Dr. Saha has received a research grant from Science and Engineering Research Board, Department of Science and Technology, India, to work on the isolation and characterization of the receptor of the motility stimulating protein that he isolated during his Ph.D. research. Two Ph.D. students are working in his lab presently.
He is a reviewer of Plos One Journal and he is a life member of the Indian Science Congress Association and the Society of Biological Chemists in India.
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10/11/2020
Updated on 11/27/2020
From: “Dr. Larry Bernstein” <larry.bernstein@gmail.com>
Reply-To: “Dr. Larry Bernstein” <larry.bernstein@gmail.com>
Date: Friday, November 27, 2020 at 2:39 PM
To: “Aviva Lev-Ari, PhD, RN” <AvivaLev-Ari@alum.berkeley.edu>
Subject: Re: DID YOU AUDIT the Podcast Dr. Williams narrated for you –>>>>>>>> e-VOICES Podcasting | Leaders in Pharmaceutical Business Intelligence (LPBI) Group
It was very well done. It is unfortunate that I only had the hemograms. Much work has been done since. Despite the progress none of the work has been introduced into daily use, or even a large trial. We did not have the enzyme data for heart attack, even though I had previously published a powerful study of heart attack using CK-MB at 0 and 8 hours later (there is a lag prior to admission) with another member of the NACB, who had also participated in the seminal code breaking trial in England. I did a repeat study on heart attack with the great Soviet mathematician, Izaak Mayzlin. This began as a resident at the University of California, San Diego, where the mathematician said he could give me brief moments of his time at no cost. Then the other critical data would pertain to sepsis based on elevated neutrophil count, which would be in part in the hemogram.
It was quite a journey.
Larry
Interview with Dr. Larry H. Bernstein, an icon in the medical field, by Dr. Stephen Williams
Welcome to E-Voices, our podcast series exploring cutting-edge science and medical topics, sponsored by the Leaders in Pharmaceutical Business Intelligence. I’m Dr. Stephen Williams, your host for this podcast.
Today’s guest is Dr. Larry H. Bernstein, M.D., FCAP, who has had a stellar career in medicine. He is a retired pathologist, pathophysiologist, histologist, bacteriologist, chemical geneticist, biochemist, enzymologist, molecular biologist and mathematical statistician.
Since Dr. Bernstein is not available to record this audio podcast with us, he provided us with answers to several questions plus gave us a biographic review of his life.
Most recently, Dr. Bernstein served as Chief of the Division of Clinical Pathology at New York Methodist Hospital-Weill Cornell Affiliate in Brooklyn, New York, followed by an interim consultancy at Norwalk Hospital in Connecticut. Previously, he was Chief of Clinical Chemistry and Chief of the Blood Bank at Bridgeport Hospital also in Connecticut and Acting Chairperson of Yale University’s Department of Pathology at Bridgeport Hospital.
For many years, he was the Chief Scientific Officer and Member of the Board of Leaders in Pharmaceutical Business Intelligence (LPBI) Group, a pharmaceutical media venture with several cloud-based products, such as an open-access online scientific journal called PharmaceuticalIntelligence.com, a BioMed e-Series of 16 volumes in Medicine, real-time press coverage of biotech and medical conferences, and a podcast library of Interviews with key opinion leaders, all involving a team of experts, authors and writers in science and medicine.
Dr. Bernstein had contributed 1,400 curated articles to LPBI’s Journal and served as an Editor and Content Consultant to each of the 16 volumes in LPBI’s BioMed e-Series. Examples of the top articles in the Journal by e-Reader views shows the cardinal positioning of Dr. Bernstein’s publications. The small sample reflects a glimpse of the topics that he had covered in his writing.
In addition, in 2020, the Journal ontology has 700 categories of research, at least 50 percent were created by Dr. Bernstein to allow precise classification of the wide range of topics his body of research had covered, namely Cancer, Genomics, Pathology, Coagulation, Cardiovascular, Nutrition, Cell Biology and biochemistry processes.
Dr. Bernstein served on the Board of Directors of NAACLS and the American Library Association Commission on Accreditation and he is listed in the America’s Top Physicians. He has three patents in the areas of malate dehydrogenase, an enzyme which plays an important role in the body’s metabolic pathway. He also co-chaired the First International Transthyrein Congress in Strasbourg, at the invitation of Yves Ingenbleek, M.D., PH.D., Professor of Pharmacology at the University of Louis Pasteur in Strasbourg. Additionally, he chaired the 14th Ross Roundtable on Nutrition and was an invited participant at the 17th Ross Roundtable and chaired the Beckman Roundtable on Prealbumin in Los Angeles, California. He was responsible for the American Association for Clinical Chemistry’s first document of Standards of Clinical Laboratory Practice with Lawrence Kaplan and he was the recipient of the Labbe/Garry award of the Nutrition Division of AACC.
We asked Dr. Bernstein if he…Could you tell us about the research project that had the most significance in his career?
He responded by saying…The mechanism of action of mitochondrial malate dehydrogenase (MDH) isonzyme and the inhibition by the combination of the reduced coenzyme (NAD+), MDH and the substrate oxaloacetate (OAA) as the forward reaction proceeds, which is similar to the reaction of lactate dehydrogenase (LDH), NAD+ and pyruvate, except for the lack of inhibition of the muscle type LDH. The role of this reaction in cancer cells, with implication for the Warburg effect…suppressed oxidation of cancer cells.
Dr. Bernstein worked with two noted researchers – Prof. Gil David, who was a postdoctoral student under Prof. Ronald Coifman, who was past Chairman of Mathematics at Yale University – to develop a software system which is today’s equivalent of electronic health records. He commented on this breakthrough and its value to patients and physicians by saying…
Prof. Gil David and Dr. Bernstein had developed, in consultation with Prof. Ronald Coifman, in the Yale University Applied Mathematics Program, a software system that is the equivalent of an Electronic Health Records Dashboard, that provides empirical medical reference and suggests quantitative diagnostics options. Their dashboard was a visual display of essential metrics.
The primary purpose of their research was to gather medical information, generate metrics, analyze the data in real-time and provide a health diagnosis for an individual’s medical condition, meeting the highest standard of accuracy. The medical diagnosis then provides a risk assessment to the patient’s medical condition, while locating and presenting similar cases of other patients with the same anomalous profile and their corresponding treatment and follow-up. Given medical information of a patient, the system builds its unique characterization and provides a list of other patients that share this unique profile, therefore utilizing the vast aggregated knowledge, such as diagnosis, analysis, treatment) of the medical community.
The main mathematical breakthroughs in creating this software system are provided by accurate patient profiling and inference methodologies in which anomalous sub-profiles are extracted and compared to potentially relevant cases. Their methodologies organize numerical medical data profiles into demographics and characteristics relevant for inference and case tracking. As the model grows and its knowledge database is extended, the diagnostic capabilities become more accurate and precise.
They anticipated that the effect of implementing this diagnostic amplifier would result in higher physician productivity at a time of great human resource limitations, safer prescribing practices, rapid identification of unusual patients, better assignment of patients to observation, inpatient beds, intensive care, or referral to clinic, shortened length of patients’ ICU and bed days.
Dr. Bernstein’s research in nutrition was extensive. He shared his early work in the Burn and Wound Care Unit at Bridgeport Hospital along with Dr. Walter Pleban, a leading physician in burn and wound care by saying…
Dr. Bernstein began the studies after reviewing the work in Boston on the evaluation of patients for malnutrition prior to surgery by an observation of arm muscle circumference weight loss and serum albumin. This was preceded by the work in Philadelphia, and later in Houston by Stanley Dudrick on malnutrition in children and in surgical patients. Dr. Dudrick became the Chairman of Surgery at Bridgeport Hospital before his retirement.
The problem that Dr. Bernstein was concerned with was the inadequacy of serum albumin, the half-life being too long. He studied the protein transthyretin (then referred to as prealbumin) after following the work by Yves Ingenbleek at the University of Louis Pasteur in France.
We asked Dr. Bernstein about his opinion on the future of cancer therapeutics.
He responded by saying…The progress has been good and has varied depending on type. There has been enormous progress in genomics, but much work on metabolic pathways is needed.
We asked Dr. Bernstein about the promise of precision medicine and what needed to be accomplished in the coming decade.
He responded by saying…that he thinks that more than a decade will be needed.
We asked Dr. Bernstein about his interpretation of COVID-19, a complex disease.
He responded by saying…It is not more complex than other viral diseases. It has come at a time that good science is not valued.
Enjoy the podcast!
Please click here to listen to an expanded life and times of Larry H. Bernstein, M.D. FCAP
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Updated on 6/3/2020
Professor Marcus Feldman Receives Stanford Biosciences Mentoring and Service Award
Reporter: Gail S. Thornton, M.A.
Marcus Feldman, Ph.D., the Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences and Professor of Biology at Stanford University, has been selected to receive the 2019-20 Stanford
Biosciences “Excellence in Mentoring and Service Award”. This honor is given to faculty who make distinguished contributions towards enhancing the quality of training and the mentoring experiences for Stanford Biosciences graduate students.
In recognizing Professor Feldman for this honor, William S. Talbot, Ph.D., Senior Associate Dean of Graduate Education and Postdoctoral Affairs,
Professor of Developmental Biology, at Stanford University, thanked him for his “extraordinary contributions this year.” Professor Feldman will be formally acknowledged for receiving this award and an honorarium at the School of Medicine Graduation Celebration on Saturday, June 13, 2020.
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UPDATED on 3/17/2020
Interview with Professor Marcus Feldman, Stanford University by Gail S. Thornton
Welcome to our podcast series exploring cutting-edge science and medical topics, sponsored by the Leaders in Pharmaceutical Business Intelligence.
Today’s guest is Professor Marcus Feldman, who is the Burnet C. and Mildred Finley Wohlford Professor in the School of Humanities and Sciences at Stanford University and co-director of Stanford Bio-X, the Stanford Cancer Institute, the Stanford Neurosciences Institute and the Stanford Woods Institute for the Environment.
He uses applied mathematics and computer modeling to simulate and analyze the process of evolution. His specific areas of research include the evolution of complex genetic systems that can undergo both natural selection and recombination, and the evolution of learning as one interface between modern methods in artificial intelligence and models of biological processes, including communication.
Most notably, he helped develop the quantitative theory of cultural evolution, which he applies to issues in human behavior, and also the theory of niche construction, which has wide applications in ecology and evolutionary analysis. He also has a large research program on demographic issues related to the gender ratio in China.
He is managing editor of Theoretical Population Biology and associate editor of the journals Genetics; Human Genomics; Complexity; the Annals of Human Genetics; and the Annals of Human Biology. He is a former editor of The American Naturalist. He is a fellow of the American Academy of Arts and Sciences and of the California Academy of Science. His work received the “Paper of the Year 2003” award in all of biomedical science from The Lancet. He has written more than 600 scientific papers and 10 books on evolution, ecology, and mathematical biology.
Enjoy the podcast!
Future podcasts will feature scientists, clinicians and researchers behind some of the most exciting medical and scientific advances in the world.
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https://soundcloud.com/user-533071695/podcast-2020-02-14-gail-thornton-interviews-prof-marcus-feldman
UPDATED on 7/4/2019
In May 2019, Aviva Lev-Ari, Ph.D., R.N., Stephen Williams, Ph.D., and Irina Robu, Ph.D., spoke with Partners in Health and Biz, an half-hour audio podcast that reaches 40,000 listeners, about the topic of 3D Medical BioPrinting Technology: A Revolution in Medicine. The topic is also the title of a recently offered e-book by the LPBI Group on 3D BioPrinting, available on Amazon/Kindle Direct
https://www.amazon.com/dp/B078QVDV2W
Please click on this link to access the audio podcast:
https://www.spreaker.com/user/pihandbiz/bioprinting-2019-final
The 3D BioPrinting technology is being used to develop advanced medical practices that will help with previously difficult processes, such as delivering drugs via micro-robots, targeting specific cancer cells and even assisting in difficult eye operations.
The table of contents in this book includes: Chapter 1: 3D Bioprinting: Latest Innovations in a Forty year-old Technology. Chapter 2: LPBI Initiative on 3D BioPrinting, Chapter 3: Cardiovascular BioPrinting, Chapter 4: Medical and Surgical Repairs – Advances in R&D Research, Chapter 5: Organ on a Chip, Chapter 6: FDA Regulatory Technology Issues, Chapter 7: DNA Origami, Chapter 8: Aptamers and 3D Scaffold Binding, Chapter 9: Advances and Future Prospects, Chapter 10: BioInks and MEMS, Chapter 11: BioMedical MEMS, Chapter 12: 3D Solid Organ Printing and Chapter 13: Medical 3D Printing: Sources and Trade Groups – List of Secondary Material.
On 3/10/2019 – Dr. Williams wrote
Notes from book on Audio Podcasting
- Microphones -MOST important part is getting a good microphone
- Yeti by Blue Micorphone BEST
- Audiotechnia ATR BEST
- Logitech is OK but not best
- Test your microphones
- Test direction of microphone – above your mouth produces a nasal sound. Microphone at your throat produces too much bass
- Test microphone distance – SPEAK in NORMAL voice then adjust the GAIN later. Note: Skype does a good job auto-adjusting the gain so don’t worry while conducting interviews about Gain issues
- Get good headphones
- Eliminates background noise. Get good headphones like BEATS STUDIO which will detect any background noise during recording.
*** NOTE if doing a co-host podcast USE SKYPE
- Recording on Skype
- Record using either the Pamela or Call recorder Program. ALWAYS CHOOSE .wav format, never .mp3 format because . wav has higher quality
- EDITING -probably the SECOND MOST IMPORTANT PROCESS. There are three suggested audio editing software programs
- Audacity – this is a FREE program
- Adobe Audition – very good but $300
- If you have a Macintosh or Apple it comes with Garageband, a very good audio editing software
- Hosting
- If uploading a weekly show you will need a hosting site with at least 125 MB capacity per month
- If using WORDPRESS use the plugin Blubrry Power Press: lets you easily put in your audiopodcast
- Upload to itunes – it takes a week but they will give you a URL so you can put it on your blog site
- On 3/9/2019 – Aviva posted
Top 10 CRISPR Podcasts Every Scientist (& Non-Scientist) by Synthego.com
Reporter: Aviva Lev-Ari, PhD, RN
- On 3/12/2015 – Dr. Williams posted
Podcast Review: Quiet Innovation Podcast on Obtaining $ for Your Startup
Reporter: Stephen J. Williams, Ph.D.
- On 1/25/2016 – Aviva posted
Launching LPBI’s, Fourth Line of Business (D): FIVE Podcast – Audio Series in BioMed
Curator: Aviva Lev-Ari, PhD, RN
- On 3/17/2016 – Aviva posted
CRISPR: A Podcast from Nature.com on Gene Editing
Reporter: Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2016/03/17/crispr-a-podcast-from-nature-com-on-gene-editing/
This page has the following sub pages.
- Partners in Health and Biz Radio Interview with Aviva Lev-Ari, Ph.D., R.N., Stephen Williams, Ph.D., and Irina Robu, Ph.D., on 5/2019 on topic of 3D Medical BioPrinting Technology: A Revolution in Medicine. Interview organizer: Gail S. Thornton, PhDc
- Podcast with Prof. Marcus W. Feldman, PhD, Biology Department, Stanford University, Interview by Gail S. Thornton, PhDc
- Podcast with Dr. Larry H. Bernstein, MD, FCAP, Interview by Gail S. Thornton, PhDc, Narrator’s Voice: Stephen J. Williams, PhD
- Podcast with Dr. Sudipta Saha, PhD, Interview by Gail S. Thornton, PhDc, Narrator’s Voice: Gail S. Thornton, PhDc