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1.0 LPBI Group’s Team created
Ten Intellectual Property Asset Classes
https://pharmaceuticalintelligence.com/2019-vista/
Contributors were:
UPDATED on 3/3/2021
Since 2012, Leaders in Pharmaceutical Business Intelligence Group (“LPBI Group”) is a leading, electronic scientific content-creation venture, offering real-time, original scientific content through advanced platform architecture and curation methodologies applied to content in Medicine, Life Sciences, Health Care and Pharmaceutical.
The company’s commitment is to synthesize, analyze and interpret complex, medical and scientific disease information through electronic publishing venues via the cloud to advance the knowledge and research efforts of the scientific and business community. LPBI is recognized as an online leader in scientific curation and dissemination, scientific communication, and medical & pharmaceutical information analysis. Over these years the LPBI Group has generated several large databases of biomedical information, highly curated by teams of scientific and medical experts. These corpuses of knowledge consist of four main sources of biomedical text including:
1) a series of 18 BioMed e-books on cancer, genomics, cardiovascular diseases, metabolomics, immunology, infectious diseases and precision medicine.
2) an Open Access Online Scientific Journal consisting of +6,000 articles in over 730 categories of research, based on an ontology created by the domain knowledge experts of the LPBI Group
3) a corpus of over 70 e-Proceedings of leading Global Scientific/Medical Conferences, reported and curated based on a methodology developed by the LPBI Group producing with one click the digital document, aka e-Proceedings of the conferences and Tweet collections digital documents of all the tweets posted during the last 36 events we covered by LPBI members of the team functioning as Press on behalf of the Conferences organizers.
4) a Gallery of 5,100 Biological Images that populate the +6,000 scientific articles. Each Image has a text legend, and often text is typed on the images to designate details portrayed on the image. Images source is in text format as well.
We are now developing a new platform, based on Blockchain technology, to allow Knowledge Workers to access, use and analyze our extensive structured knowledge databases mentioned in 1,2,3,4, above.
We are seeking Academic partners who can provide natural language processing advice and capabilities for the process of Medical Text Analysis with NLP and Deep Learning. The visualization and other digital products generated by the NLP process for each article and for collections of articles, I.e.,
A. all articles in a Chapter in a Book, and/or
B. all or a selection of Top n articles, rank ordered by # of views from all articles in one or more of the 730 categories of research assigned as main category by the author for the article fetched in the search submitted by a Knowledge Worker accessing LPBI Blockchain interface in the digital store of the premier Health Care Digital Marketplace designed and operated by an IT vendor based in Denver, CO. This vendor is designing LPBI’s Digital Store by our specifications, this design involve embedding of NLP in the blockchain API layer(s).
This new platform under design will allow scalability for the ever-increasing knowledge set we are generating.
- The text of an existing article is subjected for test analysis with NLP.
- The process generates additional blocks in the article profile:
(1) WordCloud as Abstract
(2) Bar diagram of word frequencies
(3) hyper-graph(s) and
(4) Tree diagram(s) for A and B, above and
(5) Domain knowledge expert INTERPRETATION of the visualization.
(6) Ability to specify getting this interpretation in English text format and/or getting it in several Foreign languages text.
- Content monetization take place by filling up a FORM with all the selections for content download options:
(a) the original article,
(b) one or n articles from the article set presented by the Recommendation Engine,
(c) original images and NLP generated visuals
(d) NLP results interpretation by domain knowledge experts
(e) choice of English or several Foreign languages for the text of these interpretations
- Features of the Blockchain Transactions Network will include: Permissions, Immutable LEDGER for the payments taking place prior to Permission grants to download contents, Smart contracts, Cybersecurity of the IP
We have successfully beta tested NLP algorithms on small-representative, structured datasets of articles, Text files and Biological images files.
- This proof-of-concept is now expected to compare the results LPBI generated by using Wolfram NLP Language for Biological Sciences vs the results now being produced by LINGUAMATICS, a lead NLP vendor for the Pharma industry.
- Our team and that vendor are using the same data files we produced for Phase 2 of the Proof-of-Concept project.
Our goal is to provide Knowledge Workers with a one-stop shop for Biomedical information and the means to analyze this information on an as-needed basis, i.e., the Knowledge Worker will be able to specify the sub universe of articles on which NLP algorithms are applied. The Blockchain platform with the embedded NLP will retrieve any configuration of articles and will generate the visualizations for the Text analysis with NLP.
Additional details are included in the following article:
2.0 LPBI is a Very Unique Organization
Author: Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2021/03/02/2-0-lpbi-is-a-very-unique-organization/
UPDATED on 2/25/2021
2.0 LPBI Team members are executing the following
Strategic Plan for 2021 – 2025
-
Initiative #1:
One entry for WIKIPEDIA to be recreated in 1Q 2021
Work-in-Progress
Founder of 1.0 LPBI and 2.0 LPBI – Aviva Lev-Ari, PhD, RN
-
Initiative #2:
New WebSite Design
Two Site Map Proposals for LPBI’s New Web Site
Curators: Gail S. Thornton, PhD(c) and Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2020/12/02/two-site-map-proposals-for-lpbis-new-web-site/
-
Initiative #3:
Six New Strategies for 1.0 LPBI Group’s Four of the Ten Intellectual Property Asset Classes:
Journal articles – N= +6,000 [IP Asset Class I]
Books – N=18 [IP Asset Class II]
e-Proceedings & Tweet Collections – N=100 [IP Asset Class III]
Biological Images – N=5,100 [IP Asset Class V]
To complete the Proof of Concept in Medical Text Analysis with NLP, ML-AI
• LINGUAMATICS got our Phase 2 Proof-of-Concept data files on 2/24/2021
- LPBI Team uses same data files using Wolfram’s NLP
- we need a dashboard infrastructure Off-the-Shelf i.e., Linguamatics product: Insights Hub using NLP
Content monetization: to sell Articles, Insights, Visualization and Bundled Services/Products
• Blockchain Vendor in CO will revise quote for design of a Digital Store for LPBI in theirs HEALTHCARE Digital marketplace
- we need a Blockchain Transactions System with features of: Recommendation Engine, Immutable LEDGER, Smart contracts, Permissions and cyber security for LPBI IP
The six 2.0 LPBI new strategies that represent the Pipelines for 2021 – 2025 include the following:
Strategy #1: TEXT Analysis on our CONTENTS: NLP, ML, AI – INSIGHTS MEAN VALUE and Up-selling content = NEW WARES to be brought to the market
Strategy #2: Blockchain Transactions and broadcasting to communities in the Health Care Sector – THE ONLY WAY TO MONETIZE our content by narrow casting to Health Care Communities: a Partner has lined them up and are willing to build the Front End
To accomplish Strategy #1 and Strategy #2 – a bridge investment is needed for:
- SCALING up NLP on four IP Asset Classes [Journal, Books, e-Proceeding, Biological Images], and
- Finance the BLOCKCHAIN IT infrastructure development and DATA indexing and Migration for Content Monetization: Vendor’s Quote and monthly fees till the Exit
- Finance the Content Promotion REQUIRED to generate transactions and the development of B2C opportunities
- Finance marketing effort needed for the development of B2B opportunities in Pharma & Healthcare Insurance
Strategy #3: Podcasts – will not be a Money maker – will be a Reputation Builder – very important in Pharmaceutical MEDIA
Strategy #4: Conversion e-Books to Audio and Articles to SoundCloud Audio files – Text to Audio [SEE New Yorker] – HAS POTENTIAL
Strategy #5: Joint venture with Biotech Accelerator for Drug Discovery:
We worked together in 2015-2016 for 2 years – Plan for 2020-2021: Galectins explored as drug-able by Scientists using Synthetic Biology to design new drug molecules
INTERNS are joining after Labor Day – they need to gain some LAB Flavor in return for working as Volunteers @LPBI projects: SEE
Strategy #6: e-Books Translations into Japanese, Spanish, Russian
- Decision taken to Translate to Foreign languages only two artifacts:
A. BioMed e-Series: 18 Volumes – electronic Table of Contents of each Volume
- Contains for each Book three LINKS:
BLUE – is the link to the Book on Amazon to see number of Pages & Price, Cover Page, Book Summary and Look Inside
RED – is The electronic Table of Contents (eTOCs) – Published as an article for each book on Linkedin
GREEN – is the ENTIRE book in our Cloud – In case you decide that one or all of below listed sections are needed as well for the Spanish e-Readers
B. Domain knowledge Expert’s INTERPRETATION of the NLP visualization results
- For TRANSLATION from English to Spanish, we were recommended the following two AGENCIES:
UBIQUS https://www.ubiqus.com/es/ +34 915 400 540 gestionspain@ubiqus.com
Caleidos http://www.caleidos.es/ +34 916 252 180 maria.munoz@caleidos.es
-
Initiative #4:
New Industry Partnerships for 2.0 LPBI: 2021 and Beyond
The partnerships are selected to support the development of the six New Strategies: NS #1, #2, #3, #4, #5, #6 listed in Initiative #2, above and described in great details, below
-
Explorations with a Leader NLP Vendor in Healthcare
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Explorations with Blockchain Vendors in the Healthcare Sector
-
Explorations with New Audio & Video Technologies for Podcasting
-
Explorations with Text to Audio Vendors
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Explorations with Synthetic Biology for Drug Discovery
-
Explorations with Translation Agencies in Foreign Languages
UPDATED on 2/1/2021
- Milestone achieved today
February 1, 2021 – We Celebrate 1,924,400 e-Readers, 6,000 Scientific Journal Articles, 7,525 Scientific Comments, A Journal Ontology of 728 Medical
- Thought on the transition
One Possible Strategy for an Acquisition is via a SPAC
UPDATED on 1/26/2021 – This Update is on Medical Text Analysis – Proof-of-Concept Project
- I was very happy to write for you the RSI Recommendation Letter.
- Congratulations for the TOP THREE placement on Model United Nations international conference
- I have infront of me C;ark Scholar – will work on it hopefully tonight. WITHOUT your e-mail about it – IT WAS BURIED in the Inbox of 1/8/2021
- NO Texas Tech e-mail in my Inbox. I searched for From: Texas Tech – No results
- Yes, Genomics Volume 2 will be yours for scaling from Proof-of-Concept to ONE Volume in Genomics – TILL Dr. Williams send us the following:
-
Expansion A to Proof-of-Concept
- ONE article in Cancer he selected from the 16 AND
- For that Chosen Article – what ITS is Main Category of research AND
- In which Chapter in Cancer Volume 1 it is AND
- How many OTHER articles are in this Chapter N=X
- He will make list of Articles Names and URL
-
Expansion B to Proof-of-Concept
- HE will go to THIS Main Category of research
- He will select N=X numbers of articles from THIS Main Category of research
- He will make list of Articles Names and URL
- Dr. Williams will send that information 6 to 15, above to Madison, Danielle and Aviva
-
INSTRUCTIONS for 11 and for 15, above:
- Madison will handle ALL development and #11, above
- Danielle will get instructions from Madison and handle #15, above
- FOR 11 and for 15, above – we need the following at PRIORITY #1 [expected by LINGUAMATICS – ASAP] – After Priority 1 is accomplished we MOVE to Priority 2
- PRIORITY #1 Madison : For 11 – create ONE MS Word File for each article on Article Name AND create ONE Big file for all the articles in a sequence
- PRIORITY #1 Danielle : For 15 – create ONE MS Word File for each article on Article Name AND create ONE Big file for all the articles in a sequence
- OUTPUT of 21 and of 22, above – AVIVA WILL e-mail to Jane Reed, VP Life Sciences, LINGUAMATICS – her team will perform NLP on the two TEXT files
-
Expansion C to Proof-of-Concept
- Madison uses 21, above to produce: WordClouds [WordItOut + Wolfram], BAR diagrams one per article, Hyper-graph for each article and ONE Tree Diagram for the collection of articles
- Danielle uses 22, above to produce: WordClouds [WordItOut + Wolfram], BAR diagrams one per article, Hyper-graph for each article and ONE Tree Diagram for the collection of articles
- WE WILL COMPARE 25 AND 26 WITH THE OUTPUT FROM LINGUAMATICS
- We will need to discuss with LINGUAMATICS the joint Presentation at the Healthcare Insurer.
-
SCALLING UP FROM PROOF-of-CONCEPT to Cancer Volume 1 and Genomics Volume 2 – BEGINS
- Madison, goes back to 5, above, works of Chapter 1 as an Article Collection for in Genomics Volume 2
- Danielle – Starts on Cancer Volume 1, Chapter 1 as an Article Collection
- Amanda Kaur – will perform HER Proof-of-Concept on Genomics, Volume 1, Chapter 21: CRISPR THEN start Genomics Volume 1, Chapter 1 to 20.
- Adina will start her Proof-of-Concept on 13 Articles in CVD using the Templates created by Madison
- The Medical Text Analysis Team will decide if the STORAGE of the GRAPHICS post NLP Processing will be stored in DropBox or in GoogleDocs
UPDATED on 1/25/2020 – This Update is on B2C been served by blockchain transaction network and and B2B been served by Special installations
Our Opportunities Map in this link describes the Value Drives and the Business Functions for using our products. It includes names of targeted companies.
https://pharmaceuticalintelligence.com/2019-vista/opportunities-map-in-the-acquisition-arena/
Twelve Economic Segments for LPBI Group’s IP – Prospects for Transfer of Ownership
- Holding Companies, Investment Bankers and Private Equity
- Information Technology Companies – Health Care
- Scientific Publishers
- Big Pharma
- Internet Health Care Media & Digital Health
- Online Education
- Health Insurance Companies & HMOs
- Medical and Pharma Associations
- Medical Education
- Information Syndicators
- Global Biotech & Pharmaceutical Conference Organizer
- CRO & CRA
From the List of 12 Economics Segments, above, one realizes that the market is very big for the
- Existing products and for the
- Products generated by the process of Text Analysis using Machine Learning algorithms. In addition,
- Coupling of Existing products with new graphical products generated by ML with
- an IT infrastructure with all the features of a Blockchain Transaction Processing Network represents the necessary and sufficient conditions for storage, data management and data exchange needed for enabling the following of 2.0 LPBI, 2021-2025 three missions:
- Insights from the Graphics produced by ML get the Interpretation of experts for the Medical Text semantically analyzed with Natural Language Processing, Machine Learning, Artificial Intelligence algorithms
- Content Monetization on a Blockchain Transaction Network in a Digital Store of a Healthcare Digital Marketplace allowing for B2C
- Content Monetization on a Blockchain Transaction Network serving special installations for B2B
Namely,
Special Installations for B2B for Segment 2 and Segment 4, above – will run in parallel to a Digital Store of a Healthcare Digital Marketplace allowing for B2C
Examples for Special Installations for B2B are presented, below for Segmenr 2 and Segment 4:
Economic Segment 2: Information Technology Companies – Health Care
- Amazon Web Services (AWS),
- Apple-Health,
- IBM Watson,
- Microsoft-Health,
- Oracle-Health,
- SAP Intel-Health,
Economic Segment 4: Big Pharma
- J&J,
- Pfizer,
- TEVA
UPDATED on 1/13/2021 – This Update defines the Outputs of NLP on LPBI content in Text and Image format
- We will have from our IT Vendor a BLUEPRINTS for the content monetization system design with all the components laid out in a workflow for a production process to incorporate two sources of data:
1.0 LPBI four IP Asset Classes: I, II, III, V will be available for monetization
The Design include all monetization Features to incorporate the 2.0 LPBI NEWLY TO BE CREATED PRODUCTS by NLP integrated at the article level with the 1.0 LPBI IP.
We will generate four Text Analysis products, like the FOUR outcomes of NLP included in the Proof-of-Concept:
NLP Products: Will be available for monetization as 2.0 LPBI IP:
- WordClouds,
- Bar charts,
- Hyper-graphs and
- Expert Interpretation in English and Foreign Languages
PHASE I: All Articles in ALL Books at the Chapter Level – THEY WILL HAVE:
- WordClouds,
- Bar charts,
- Hyper-graphs and
- Expert Interpretation in English and Foreign Languages
For:
Series A: 6 volumes,
Series B: 2 volumes
Series C: 2 volumes
Series D: 4 volumes – 1, 2&3 in one Book, 4
Series E: 4 volumes
Total 17 Books for 18 Volumes
PHASE II: All Articles Not in Books and Not as e-Proceedings – THEY WILL HAVE:
- WordClouds,
- Bar charts,
- Hyper-graphs and
- Expert Interpretation in English and Foreign Languages
PHASE III: 60 e-Proceedings + 36 Tweet Collections – THEY WILL HAVE:
- WordClouds,
- Bar charts,
- Hyper-graphs and
- Expert Interpretation in English and Foreign Languages
PHASE IV: 5,100 Biological Images – THEY WILL HAVE:
- WordClouds,
- Bar charts,
- Hyper-graphs and
- Expert Interpretation in English and Foreign Languages
UPDATES on 1/8/2021 – This Update is on Strategy #1 and Strategy #2
Description of 2.0 LPBI
Medical Text Analysis using NLP, ML-AI on our own content generated, 2012-2020: 6000 Journal articles, 17 e-Books in Medicine, 100 e-Proceedings & Tweet Collections and +5000 Biological images
Content Monetization system development for
(a) EXISTING digital products and
(b) the results of Medical Text Analysis using NLP, ML-AI: WordClouds & Hyper-graphs
- LPBI created a e-Scientific Publishing venture second to none – based on ~2MM Views has projected revenues to $ZZZ MM
- The Content Monetization Cloud-based IT System DESIGN will have features of Blockchain transaction network: PERMISSIONS, LEDGER, RECOMMENDATION ENGINE
- System integration for 1 and 2
In addition, DESIGN of CONTENT PROMOTION campaigns
- We need to be teamed up with a Partner or an inside Group to XXX for the DESIGN of CONTENT PROMOTION campaigns for (1.0 LPBI IP[digital products: journal articles, e-Proceedings, Tweet Collections, Biological images]
- Upon progress with content promotion for existing digital products, same effort needs to be developed for 2.0 LPBI IP, named, the results of Text Analysis with NLP, ML-AI. This newly created IP, as well needs DESIGN of CONTENT PROMOTION campaign for WordClouds, Hyper-graphs and Domain Expert Interpretation of the Hyper-graphs in foreign languages
All developments realted to Technologies applied by 2.0 LPBI are to be found in the following article.
Data Architecture for Blockchain Deployment of Digital Assets: LPBI IP Asset Classes I,II,III,V
Author: Aviva Lev-Ari, PhD, RN
UPDATED on 12/22/2020 – This Update described four initiatives for 2.0 LPBI
Development and Execution of 2020-2021 Vision for 2.0 LPBI
https://pharmaceuticalintelligence.com/vision/
-
2.0 LPBI, 2021 – 2025, will pursue four initiatives:
Initiative #1. Wikipedia presence
Initiative #2. New Web Site Design
Two Site Map Proposals for LPBI’s New Web Site
Curators: Gail S. Thornton, PhD(c) and Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2020/12/02/two-site-map-proposals-for-lpbis-new-web-site/
Initiative #3. Six New Strategies
Initiative #4. New Technology Partnerships for 3.1 to 3.6, below
Initiative #3 – Six New Strategies: Overview description
UPDATED on 12/30/2020 – This Update defines a Longitudinal Profile for the Unit Case: “Article”
For the DESIGN of IT Infrastructure for Monetization, the following is an essential
DEFINITION for “PROFILE of an Article”:
1.0 LPBI BEGINS
Monetization of 6,000 Digital Products – A Unit Case: A Journal Article
5.0 Article Title
5.0.1 Article URL
5.0.2 Author 1: Name
5.0.2.1 Author 2: Name
5.0.2.2 Author 3: Name
5.0.2.3 Author 4: Name
5.0.3 Date of Publication
5.0.4 # Words
5.0.5 # Views since Published to DATE
5.1 Is the article in a Book?
5.1.1 Article is not in a Book only in the Journal
5.2 Article is in a Book – In which one(s)?
5.2.1 LPBI Series A
5.2.1.1 Volume 1
5.2.1.2 Volume 2
5.2.1.3 Volume 3
5.2.1.4 Volume 4
5.2.1.5 Volume 5
5.2.1.6 Volume 6
5.2.2 LPBI Series B
5.2.2.1 Volume 1
5.2.2.2 Volume 2
5.2.3 LPBI Series C
5.2.3.1 Volume 1
5.2.3.2 Volume 2
5.2.4 LPBI Series D
5.2.4.1 Volume 1
5.2.4.2 Volume 2
5.2.4.3 Volume 3
5.2.4.4 Volume 4 [Dr. Williams and Dr. Irina are adding editorials, NOW]
5.2.5 LPBI Series E
5.2.5.1 Volume 1
5.2.5.2 Volume 2
5.2.5.3 Volume 3
5.2.5.4 Volume 4
1.0 LPBI ENDS
2.0 LPBI BEGINS: Medical Text Analysis (NLP, ML, AI) (SaaS) and
Monetization of Text Analysis Results as Products (Blockchain as a Service (BaaS)
5.3 Does article have the Text Analysis features:
5.3.1. a WordCloud – needs to be stored in graph file of WordClouds
5.3.2. # words used
5.3.3. Hyper-graphs – need to be stored in graph file of Hyper-graphs
5.3.3.1 One Hyper-graph for All articles in a Book Chapter
5.3.3.2 One Super-graph for All articles in one or more Categories of Research – need to be stored in graph file of Super-graphs
5.3.4. Domain Expert interpretation for 5.3.3.
5.3.4.1 Domain Expert interpretation for 5.3.3.1
5.3.4.2 Domain Expert interpretation for 5.3.3.2
5.4 Audio File added to Article
5.4.1 In place – Audio file type [Text to Audio]
5.4.1 SoundCloud file
5.5 Article Titles was translated to
5.5.1 Spanish
5.5.2 Japanese
5.5.3 Russian
12/30/2020 – This Update is on Medical Text Analysis with NLP
We are facing FIRST the following challenges:
1. When we apply NLP on ONE article NLP yields a WordCloud
2. When we apply NLP on all the articles in ONE book’s electronic Table of Contents (eTOCs)
- NLP yields a Hyper-graph
3. When we apply NLP on all the Hyper-graphs of one Books (all chapters)
- NLP yields a Super-graph
Linguamatics has capabilities for using as input
1,2,3, above and can be combined INSIGHTS from LPBI CONTENT with Disparate Data sources for a newly defined purpose
- It is that stage WHEN 1.0 LPBI IP will yield a Software as a Service (SaaS):
If we RUN NLP on 1.2,3 and Disparate Data Source:
Like EMR as a data source
or
Like Drug Formulary or Clinical Trials as a data source
The output creates a different set of Recommendations:
• If EMR then Insights will serve a Healthcare Insurer
• If Drug Formulary and Clinical Trials then Insights will serve a Big Pharma
UPDATED on 12/28/2020 – This Update is on Translation from English to Spanish the eTOCs of 18 books in Medicine
New:
I had Zoom with C. Cxxxx in Barcelona. She works for a Pharmaceutical Publisher in Spain
• She will present at 12:45PM EST on 1/12/2021 – Our 2.0 LPBI first Global Zoom Updates to agenda on Calendar. She is sending us contacts and may
• Translate all 16 electronic Table of Contents of the e-Books to Spanish and
• Connect us with Marketing Departments in all big Pharma and market entry into Latin America Pharmaceutic Publishing sectors
New:
Progress was achieved by our Medical Text Analysis Team using NLP, per Madison Davis e-mail of Yesterday.
WHEN that is completed and AWS-IT Cloud Vendor will have an architecture to scale
• We will Zoom with Dr. R G of XXX the Healthcare Insurer awaiting for the Proof of Concept
New:
I requested JP, AWS and another AWS person to help me be introduced to two different departments at AWS:
1. Decision makers of who to talk to about having 2.0 LPBI become a participant at AWS Marketplace offering Services accessible to all other AWS Marketplace members
2. Decision makers of who to talk to in the AWS Venture Acquisition Department.
• They will get back to me.
New:
We need an IT Cloud Vendor for
1. Scaling from Proof of Concept to Production NLP, ML, AI using AWS infrastructure
2. Architecture to monetize IP Assets – AWS HyperLedger with some functionality of Blockchain vs Blockchain forthcoming revised Quote from YYYY
3. IT Cloud Vendor to present with us 1, above to Dr. R G on xxx Healthcare Insurer – as our Business Partner
4. For our Exit: the output of IT Cloud Vendor and YYY (blockchain leader) and zzzz (NLP in Life Sciences Leader) on 1 & 2 above – served as pipeline business development PLAN AND INVESTMENT COSTS to be Addendum to Master_Financials Excel File
3.1 NLP, ML, AI on our four Corpuses of Intellectual Property (IP) assets:
12/22/2020 – This Update describes LPBI’s IP Asset Classes appropriate for Text Analysis with NLP
3.1.1 1.0 LPBI IP Asset Classes relevant for AI-ML
3.1.1.1 6,000 journal articles
3.1.1.2 16 eBooks in Medicine
3.1.1.3 100 eProceedings and Tweet Collections of top Biotech and Medical Global Conference we covered in Real Time – See Press Coverage
3.1.1.4 Gallery of 5,100 Biological Images
3.1.1.5 Content aggregation via Categories of Research combinations – 720 Categories of Research make the Journal Ontology
3.1.2 NLP Artifact Files & Database
3.1.2.1 WordClouds for 3.1.1.1 – 3.1.1.3
3.1.2.2 Number of Words in use for WordCloud generation
3.1.2.3 Hyper-graphs: Graph Files & Databases for 3.1.1.1 – 3.1.1.3
3.1.2.4 Experts Interpretation of Hyper-graphs: Text files & Graph Files Databases
3.2 Monetization of 3.1 [3.1.1 & 3.1.2] using Blockchain Transaction Network, digital store in Healthcare Digital Marketplace
3.3 Podcast Library Development
3.4 Conversion of 3.1.1.1– 3.1.1.3 from English Text to English Audio
3.5 Joint venture on Synthetic Biology in Drug Development of Galectins with SBH Sciences, Inc at ABI-LAB
3.6 Conversion of 3.1.1.2 [electronic Table of Contents] to Foreign Languages: Japanese, Spanish, Russian
UPDATED on 11/27/2020 – This Update describes 2021-2025 Vision for LPBI
2.0 LPBI Executive Summary
2.0 LPBI Brochure
- Password protected document – request access by Contact us
Knowledge PORTALS System (KPS) @LPBI
- Knowledge PORTALS System (KPS) @LPBI is an initiative launched in September 2020 to manage the content creation @LPBI by our Final Improvement Team (FIT) members during the Transition Period that started on March 14, 2020 with the Launch of the Coronavirus Portal to cover eight aspects of the SARS-CoV-2 Pandemic @LPBI and which will end when CDC will announce that this Pandemic is over.
2020 VISTA 1.0 LPBI
https://pharmaceuticalintelligence.com/2019-vista/
1.0 LPBI Executive Summary
1.0 LPBI Brochure
- Password protected document – request access by Contact us
Elevator Pitch
2.0 LPBI Group’s Team Members
https://pharmaceuticalintelligence.com/knowledge-portals-system-kps/
2.0 LPBI Executive Summary
A New Team was put in place for the development of the pipelines defining the future prospect of 1.0 LPBI Group’s portfolio of IP and the opportunities for 2.0 LPBI Group’s Team.
2.0 LPBI Group’s Team
- Aviva Lev-Ari, PhD, RN, Founder, LPBI Group: 1.0 & 2.0
- Marcus Feldman, PhD, Member of the Board, Scientific Counsel: Life Sciences
- Stephen J. Williams, Member of the Board, Chief Scientific Officer, Senior Editor, PhD Pharmacology, BSc Toxicology
- Joel Shertok, PhD, Member of The Board, Business Development and Process Designer of a Global AI-based External Relations Prospecting System for LPBI Group
- Justin D. Pearlman, MD, PhD, FACC – Scientific Expert & Key Opinion Leader on Cardiovascular Diseases, Cardiac Imaging & Complex Diagnosis in Cardiology: Senior Editor & Author
- Sudipta Saha, PhD, Expert, Author, Writer, Co-Editor, Series D, Volume 2: Infectious Diseases
- Irina Robu, PhD – 3D BioPrinting, Tissue Engineering, Biomaterials, Nanotechnology & Drug Delivery
- Gail S. Thornton, PhD(c), Contributing Editor, Author and Medical Writer, Marketing Communications
- Ofer Markman, PhD – Advisor to LPBI Group’s Founder on the Biotech Ecosystem in Israel and Domain Expert on Text Analysis with ML
2020-21 Visions include the new Pipelines and the Strategic Plans for 2.0 LPBI: 2021 – 2025
https://pharmaceuticalintelligence.com/vision/
LPBI Group generates vast scientific content via industry thought leaders through multiple platforms and makes it universally accessible. The challenge for the future is the development of several, i.e., the following six new strategies for creation of Value added Services and Products.
2.0 LPBI Team members are executing the following
Strategic Plan for 2021 – 2025
-
Initiative #1:
One entry for WIKIPEDIA to be recreated in 1Q 2021
Work-in-Progress
Founder of 1.0 LPBI and 2.0 LPBI – Aviva Lev-Ari, PhD, RN
-
Initiative #2:
New WebSite Design
Two Site Map Proposals for LPBI’s New Web Site
Curators: Gail S. Thornton, PhD(c) and Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2020/12/02/two-site-map-proposals-for-lpbis-new-web-site/
-
Initiative #3:
Six New Strategies for 1.0 LPBI Group’s Ten Intellectual Property Asset Classes
To complete the Proof of Concept
• we need a dashboard infrastructure Off-the-Shelf i.e., Linguamatics product: Insights Hub using NLP
To sell Articles, Insights, Visualization and Bundled Services/Products
• we need a Transaction System, I.e., a Healthcare Blockchain vendor
The six 2.0 LPBI new strategies that represent the Pipelines for 2021 – 2025 include the following:
Strategy #1: TEXT Analysis on our CONTENTS: NLP, ML, AI – INSIGHTS MEAN VALUE and Up-selling content = NEW WARES to be brought to the market
Strategy #2: Blockchain Transactions and broadcasting to communities in the Health Care Sector – THE ONLY WAY TO MONETIZE our content by narrow casting to Health Care Communities: a Partner has lined them up and are willing to build the Front End
Strategy #3: Podcasts – will not be a Money maker – will be a Reputation Builder – very important in Pharmaceutical MEDIA
Strategy #4: Conversion e-Books to Audio and Articles to SoundCloud Audio files – Text to Audio [SEE New Yorker] – HAS POTENTIAL
Strategy #5: Joint venture with Biotech Accelerator for Drug Discovery:
We worked together in 2015-2016 for 2 years – Plan for 2020-2021: Galectins explored as drug-able by Scientists using Synthetic Biology to design new drug molecules
INTERNS are joining after Labor Day – they need to gain some LAB Flavor in return for working as Volunteers @LPBI projects: SEE
Strategy #6: e-Books Translations into Japanese, Spanish, Russian
- For TRANSLATION from English to Spanish, we were recommended the following two AGENCIES:
UBIQUS https://www.ubiqus.com/es/ +34 915 400 540 gestionspain@ubiqus.com
Caleidos http://www.caleidos.es/ +34 916 252 180 maria.munoz@caleidos.es
-
Initiative #4:
New Industry Partnerships for 2.0 LPBI: 2021 and Beyond
The partnerships are selected to support the development of the six New Strategies: NS #1, #2, #3, #4, #5, #6 listed in Initiative #2, above and described in great details, below
-
Explorations with a Leader NLP Vendor in Healthcare
-
Explorations with Blockchain Vendors in the Healthcare Sector
-
Explorations with New Audio & Video Technologies for Podcasting
-
Explorations with Text to Audio Vendors
-
Explorations with Synthetic Biology for Drug Discovery
-
Explorations with Translation Agencies in Foreign Languages
2.0 LPBI – 2021 and Beyond
The New Strategies: NS #1, #2, #3, #4, #5, #6
Updated on 12/28/2020
WHAT IS IN THE INVENTORY?
In 2021 we have for Monetization:
1. Four IP Asset Classes:
(a) 6,000 articles
(b) 16 Books & each article in every Book
(c) 100 Documents: e-Proceedings and Tweet Collections
(d) 5,100 Biological Images inside curated content
2022-2025 – A Strategy of New Product Development (based on existing Four IP Asset Classes) by Type:
2. 6,000 Articles as Audio Files – embedded SoundCloud file inside the articles, one per article
3. 6,000 WordClouds
4. 6,000 NLP HyperGraphs – Graph files or Images
5. Each article has on average ~6 Categories of Research –
5a. When a Topic is selected the computer needs to present 10-12 alternative related articles from several categories assigned by the Author by his/her selection of cardinal Research Categories – A Smart guided Recommendation Engine
5b. One hyper-graph for all the articles in One category of Research the article belongs to,
5c. One hyper-graph for each of the “on average ~6 Categories of Research for each article”
5d. New Corpus of hyper-graph Expert Interpretation: searchable, sorted and reusable
• How could we present a universe of up to 12 articles to choose from BUT allow to download one or more from the alternative of 12 ONLY after a payment for each had credited 2.0 LPBI account. That activity requires Blockchain not only a PayPal
• Who will perform FULFILLMENT – approval of the download only of the article ID matched to the one paid for by the e-Reader.
You pay for one download once.
vs
You pay for one download of all the choices you browse to select only one
• that is a feature that Blockchain offer
• prevention of downloading items Not paid for
• storage of 1 to 5, above including 6,000 X new types of the original article: Audio or Translation
Blockchain will allows selling 1 to 5, above – that is Blookchain as a Service (BaaS)
2021 we have for Monetization – Continued:
6. 16 Books in English
2022-25
7. 16 Audio Books in English (or other foreign languages)
8. XYZ articles for sell as “Articles published in Books” vs “Journal Articles”
9. 16 Books in Spanish – May be also 16 Audio books in Spanish
10. 16 Books in Japanese – May be Audio books in Japanese
11. 16 Books in Russian – May be Audio books in Russian
If we sell e-Books on Amazon.com we get 35% of book price
• Page downloads equivalent to 52 books 📚 not sold – 125,000 Page downloads as of 8/31/2020
• If Books are ready for FULFILLMENT on Digital Store in Blockchain Marketplace THEN 7 to 11 above is at Full book price not at 35% we will charge for Page download $2.25 vs 0.005 cents paid to us as Royalties
12. 2021 we have for sell 60 eProceedings and 36 Tweet Collections – Profile Meta Data is different than a Journal Article or an e-Book
We have no platform to sell them
• Blockchain will do the job
AWS is what we wish to consider
Amazon Advertising – we will need to use. I set up an experiment for Genomics Volume 2 in UK, my budget is $200
90 days of advertisement AUCTION 0.45 GBP per ad.
I need to get VAT from Amazon UK to place the Advertisement
- Requires Experimental Design: Which book in which Country, duration of Experiment by advertisement using AUCTION
- Compare analytics – the e-Book Sales vs cost of Advertisement across several Books in different times of the Year
We have a quote of $$$ to handle (Data engineering included) – Only of the following LPBI IP Asset Classes:
• 6000 article
• 16 Books
• 100 e-Proceedings/Tweet Collection
@@@@@@@@@@@ THAT does not include the other numbers of 1 to 12 above
Who will update the Digital Store with new items to be indexed as they become available
Running NLP on LPBI Content Types will yield a New Corpus of Knowledge: a DB of Hyper-graphs
• all articles in Research category “cell biology” will yield a
Hypergraph, hg1
• all articles on Cancer cell biology will yield a
Hypergraph, hg2
• all e-Proceeding of Cancer Conferences will yield a
Hypergraph, hg3
• Genomics volume 1 will yield a Hypergraph, hg4
• Cancer Volume 2 will yield a Hypergraph, hg5
We need a DB for Hyper-graphs: hg(1) to hg(n)
• Hyper-graphs need to be stored in a DB of graph files or of Images – annotated and searchable
AVAILABLE for download and one needs to pay for the download
- each Hyper-graph will be CREATED FROM PROPRIETARY Content, aka, the LPBI IP subjected to Text Analysis DONE BY ML-NLP-based algorithms
- NOT ALIKE to running NLP on PubMed, Content is in the public domain in a searchable DB by KEYS: keyword/author name/date of publication
IF
we execute on 2.0 LPBI Medical Text Analysis Strategy
THEN
monetization is
NOT only of the
• IP Asset Class I (Journal Articles), II (e-Books), III (e-Proceedings+Tweet Collections), and V (Image Gallery)
BUT
• all the RESULTING Products from 1 to 12, above
We will be developing TWO new Services using our content:
Strategic Concepts Defined
1. Insights as a Service [IaaS] – Consultancy with Big Pharma on our Insights from the Curations
Medical Text Analysis – Features of Linguamatics Infrastructure SW:
- infrastructure for text analysis with NLP, AI/ML for lIfe sciences – We need the dashboard for the interpretation after the hyper graphs are created by the NLP algorithm – They have it.
- We will get a quote from Linguamatics for a new Off-the-Shelf Suite – We will use it for LPBI’s cost of performing medical text analysis for the Health-Care Insurer at UT. That suite is part of materials + labor used in billing.
- We need to find an Off-the-Shelf Suite that has
- Data ingress –
- Text processing with NLP, AI/ML
- Output with visualization
Analytics of patterns known in the Life Sciences – comparison of what is found in our Text vs Patterns representing known relations in the biological sciences. Linguamatics has developed the infrastructure to host
(a) Dictionaries for Pharmaceutics Formulary
(b) Biological Pathways
(c) Medical Terminology
(d) PubMed
LPBI will be more valuable, credible and authentic if we can demonstrate:
- Understanding of the infrastructure required to enable medical text analysis of LPBI’s IP
- Understanding the ecosystem of vendors for such an undertaking: medical text analysis with NLP, AI/ML
- If we claim that our curations are unique, then we should be able to perform the text analysis and show visually the insights uncovered using the hypergraphs known in the Life Sciences – they have the suite we need to use to do the job of medical text analysis.
- We will get a quote and compare it with Wolfram Environment for NLP
- We do our homework, get prices and relationships with vendors lined up
- We are ready to ROLL if the Acquirer supports the directions
We are lining up all the players that will enable us to develop the CONCEPT of a full flag Service Description for:
A. Insights as a Service (IaaS):
What 2.0 LPBI is including in a consulting program for Big Pharma for $X00,000 an engagement with a Demo
a.1 Medical Therapy selected – Expert input
a.2 Categories of Research in the Journal that contain the articles of relevance – Expert input
a.3 TEXT ANALYSIS process using platform I.e., Linguamatics or other vendor
a.4 Visualization of Solutions
a.5 Recommendations to Big Pharma
We need several a.1, each one for another medical indication per our Cardiovascular, Genomics, Cancer, Immunology, Precision Medicine – content universes
2. Blockchain as a Service [BaaS] for transactions for content information syndicator
We are not making any expense; we need few bids to understand the cost involved in getting the infrastructure to sell one article for $30
- Without such an infrastructure we will not be able to monetize our content. ALL WE HAVE is CONTENT and PEOPLE.
- If we have our own a Business Account for LPBI on PayPal.com that will record the AR and AP, then
- Who will do fulfillment? namely, displaying the articles to choose from, allowing download of the content and monitoring access only to the articles downloaded – PAY per CLICK model –
- PayPal does not do that. Indexing the N=6,000 is step one. Search and display several related articles to select only the one needed.
- Upon selection, access permit needs to be granted online and the Transaction need to be recorded.
LPBI is more valuable, credible and authentic if we are able to demonstrate:
- Understanding of the infrastructure required to enable monetization of the IP
- Understanding of the ecosystem of Healthcare Blockchain vendors for such an infrastructure
- If we claim that one article would sell for $30, then we have to figure out what it takes to enable a customer to pay per click and download the content he/she chooses from a selection of related articles presented to him/her by the system
B. Blockchain as a Service (BaaS)
What 2.0 LPBI will be narrow casting as an offering?
a.1, a.2, a.4, a.5, above – bundled for Customers of a HealthCare Blockchain Marketplace Exchange – we need relations with all aggregators of Healthcare Customers to promote our Insights as a Service (IaaS)
Healthcare Blockchain Market place is where we plan to sell IaaS
Our Digital Store on the Exchange which stores all our products: I.e., journal articles:
Article #1
Article #2
.
.
.
Article #6,000
Blockchain products indexed will enable to do a.2: search by category, it will as well enable to store a.4 and a.5, above
- It is only a.3, above – the actual NLP, ML Text Processing and Analysis will be done outside the blockchain on a platform like Linguamatics’ Insight Hub
We plan to sell Insights as a consultancy that requires Indexing and storage of Insights per Medical Indication – that is similar to the article inventory “bar coded” by an n-dimensional indexing data scheme
Following the Text Analysis phase – the Text Analysis Outcomes will be stored for reuse and recombination ready for Trade.
The Blockchain Transaction System will provide these features of the infrastructure as well as will record the trade and grant access to
• select
• pay
• download selected content
2.0 LPBI would use Blockchain creatively NOT for only what it was originally designed for, but also for UP-SELLING 1.0 LPBI content:
SELLING 1.0 LPBI content is
• downloading one article for $30
n=6,000
UP-SELLING 1.0 LPBI content is
• downloading Insights generated by Text Analysis using NLP, AI/ML.
SELLING 1.0 LPBI Graphic Images $100
n=5,100
UP-SELLING 1.0 LPBI Graphical visualization of semantic relations in Image format is
• downloading Visualizations of hypergraphs generated by Text Analysis using NLP, AI/ML
When 2.0 LPBI Sell an item and a Customer pay 💰 a Transaction Network infrastructure, I.e., Blockchain, needs to be custodian of the trade
We will need to Price Insights and Visualization PRODUCED in the Text Analysis phase.
IaaS and BaaS are designed ON TOP OF 1.0 LPBI Products, IaaS and BaaS need to be explained as 2.0 LPBI strategy:
We need to complete the Proof of Concept to get SAMPLES of
• Insights
• Visualization of Semantic Hypergraphs
• Bundle for IaaS consulting the following components:
(a) Articles
(b) graphics
(c) Insights
(d) visualization of hyper-graphs generated as an outcome from the Text Analysis with NLP phase
To complete the Proof of Concept
• we need a dashboard infrastructure Off-the-Shelf i.e., Linguamatics product: Insights Hub
To sell Articles, Insights, Visualization and Bundled Services/Products
• we need a Transaction System, I.e., a Healthcare Blockchain vendor
Perspectives on the INTEGRATION of NLP and Blockchain
2021 we have for Monetization:
1. 6,000 articles
2022-25 we will have for Monetization:
2. 6,000 Audio Files
3. 6,000 WordClouds
4. 6,000 NLP HyperGraphs
5. 5,100 Biological Graphs
6. Each article has ~6 Categories of Research – When a Topic is selected the computer needs to present 10 alternative related articles from several categories assigned by the Author
Implementation issues addressed:
#1: Infrastructure design issues
- How you present a universe of up to ten articles to choose from BUT allow to download one or more from the alternative of 10 ONLY after a payment for each had credited 2.0 LPBI account.
That activity requires Blockchain not only a PayPal
- Who will perform FULFILLMENT – approval of the download only of the article ID matched to the one paid for by the e-Reader.
You pay for one download one.
vs
You pay for one download all the choices you browse to select only one
• that is a feature that Blockchain offer
• prevention of downloading items Noy paid for
• storage of 1 to 6, above including 6,000 X new types of the original article
Blockchain will allows selling 1 to 6, above – that is Blockchain as a Service (BaaS)
In 2021 we have for Monetization:
7. 16 Books in English
In 2022-25 we will have for Monetization:
8. 16 Audio Books in English (or other foreign languages)
9. XYZ articles for sell as “Articles published in Books” vs “Journal Articles”
10. 16 Books in Spanish
11. 16 Books in Japanese
12. 16 Books in Russian
BioMed e-Series: If we sell on Amazon.com
- we get 35% of book price
- Page downloads of 125,000 equivalent to 52 book 📚 not sold
If Books are ready for FULFILLMENT on Digital Store in Blockchain Marketplace THEN
- 7 to 12 above is at Full book price not at 35%
- we charge for Page down load $2.25 vs 0.005 cents
13. 2021 we have for sell 60 eProceedings and 36 Tweet Collections
- We have no platform to sell them
- Blockchain will do the job
AWS has a platform allowing to Integrate NLP with Blockchain
Amazon Advertising – we will need to use without Narrow casting and Promotion – no sales will occur
- I set up an experiment for Genomics Volume 2 in UK, my budget is $200
- 90 days of advertisement AUCTION 0.45 GBP per ad.
- I need to get VAT from Amazon UK to place the Advertisement
We have a quote of $XXX,XXX from a blockchain vendor in CO to handle: IP Assets I,II,III
• 6000 article
• 16 Books
• 100 e-Proceedings/Tweet Collection
THAT does not include the other numbers of 1 to 13 above
THAT does not include NLP and Blockchain integration
#2 Ongoing Data Updates
- Who will update the data stored in Blockchain with new items to be indexed as they become available
#3 Scaling Up
Example:
Running NLP on
• all articles in Research category “cell biology” will yield a
Hypergraph, hg1
• all articles on Cancer cell biology will yield a
Hypergraph, hg2
• all e-Proceeding on Cancer will yield a
Hypergraph, hg3
• Genomics volume 1 will yield a Hyper-graph, hg4
We need a DB for hg(1) to hg(n)
We need that Hyper-graphs will be stored in a DB of images – annotated and searchable
Hyper-graphs AVAILABLE for download
e-Readers needs to pay for the download
Hyper-graphs were CREATE FROM PROPRIETARY Content, aka LPBI IP via Text Analysis on the CONTEXT OF THE CONTENT curated by experts defining What a sub-context is in a domain
Versus
Running NLP on PubMed content in the public domain searchable by date of publication, keyword in title and author name
IF we execute on Medical Text Analysis THEN
WHAT we have for monetization is NOT only
• IP Asset Class I (journal articles), II (e-Books), III (e-Proceedings), V (Image Gallery)
BUT
• all the RESULTS from 1 to 13 above minus numbers not related to NLP strategy.
Founder’s VISION Updated on 11/27/2020
Initiative #1:
One entry for WIKIPEDIA to be recreated in 1Q 2021
Founder of 1.0 LPBI and 2.0 LPBI – Aviva Lev-Ari, PhD, RN
- Work-in-Progress
Initiative #2:
Planning & Launch of a New Web Site for 2.0 LPBI – work-in-progress
Website Design for the New Strategies (NS)
Two Site Map Proposals for LPBI’s New Web Site
Curators: Gail S. Thornton, PhD(c) and Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2020/12/02/two-site-map-proposals-for-lpbis-new-web-site/
- Work to start by Gail, Aviva in December 2020
New SITE MAP under a newly to be selected WordPress.com Theme:
LPBI 2012-2025 – NEW WEB SITE for 2021 – 2025
OUR HISTORY
- 1.0 LPBI is our Current Website http://pharmaceuticalintelligence.com
- Calling 4/2012 to 12/2020 (1.0 LPBI) – OUR HISTORY
- It will become the BACK-END of the New Web Site, aka, 2.0 LPBI with a FRONT-END Interface
OUR FUTURE
- 2.0 LPBI – will be our NEW WEB SITE about 2021 and BEYOND
- Work on the New WEBSITE to start in December 2020 by Gail, Aviva, Inbar
Site Map Version 1: Proposal by Aviva
2021-2025: 2.0 LPBI SITE MAP
2.0 LPBI:
- Executive Summary
- Brochure
- Vision
- Team’s Knowledge Portals System
PRODUCTS
- Digital Text & Image Products
- 6,000 Articles
- Article Abstract in WordClouds Images [2020 Summer Internship]
- Gallery of +5,000 Biological Images
- Audio Products:
- Articles in SoundCloud files
- Audio Books in Medicine
- Biotech & Medical Conference e-Proceedings
- Tweet Collections
- BioMed e-Series Electronic Books in Foreign Languages
- 16 e-Volumes in Japanese
- 16 e-Volumes in Spanish
- 16 e-Volumes in Russian
SERVICES
- AI/ML: Genomics & Cancer
- Insights as a Service [IaaS]: 2021 Medical Text Analysis using NLP, ML, AI
- Blockchain as a Service [BaaS]: Content Trade using Transactions System for a Digital Store on a Healthcare Marketplace functioning as an Exchange
- e-Voices Podcasting
- Drug Discovery using Synthetic Biology – JV
- Customer Surveys
ABOUT
- Testimonials
- Board Members
- Founder
- Coronavirus Portal
- Quarterly Newsletters
- Current News
- Calendar
- Contact us
2012-2020: 1.0 LPBI SITE MAP
https://pharmaceuticalintelligence.com/
1.0 LPBI:
- Executive Summary
- Brochure
- History
- VISTA for Exit
- Our Team of Contributors, 2012 – 2020
- Investor Relations
Digital PRODUCTS
- Journal PharmaceuticalIntelligence.com: 6,000 articles
- BioMed e-Series: e-Books
- Press Coverage: e-Proceedings
- Social Media Coverage: Tweet Collections
Business SERVICES
- Funding, Deals & Partnerships
- Healthcare Investor’s Corner
ABOUT
- Testimonials
- Board Members
- Founder
- Coronavirus Portal
- Quarterly Newsletters
- Current News
- Calendar
- Contact us
@@@@@
Site Map Version 2: Proposal by Gail S. Thornton
Draft updated: 11/30/2020
Site Map
Connect With Us Search
Leaders in Pharmaceutical Business Intelligence Group
Note: Our Company, Our Services, Our Commitment are major buckets in this order.
Our Company Our Services
About Us Pharmaceutical e-journal
Leadership
Board Members AI / ML: Genomics, Cancer
Executive Team Biomed e-books
History Audio and Foreign language books
Locations Conference e-Proceedings
Testimonials Podcasts
Newsletters
Coronavirus portal
Medical text analysis
Blockchain technology
Calendar
Our Commitment
LPBI 2.0
Executive Summary
Vision
Brochure
Knowledge Portals
LPBI 1.0
Executive Summary
Vision
Brochure
Summer Internship Program
WordCloud article abstracts
Drug Discovery
Joint ventures
Investor Relations
Health care Investors’ Corner
Customer Surveys
@@@@
Initiative #3:
2.0 LPBI Strategy: 2021 and Beyond
2.0 LPBI entry will cover the New Strategies: NS #1, #2, #3, #4, #5, #6
Strategy #1: TEXT Analysis on our CONTENTS: NLP, ML, AI – INSIGHTS MEAN VALUE and Up-selling content = NEW WARES to be brought to the market by NLP applications.
- Machine learning, data mining, and statistical pattern recognition.
- Supervised learning (parametric/non-parametric algorithms, support vector machines, kernels, neural networks).
- Unsupervised learning (clustering, dimensionality reduction, recommender systems, deep learning)
- Best practices in machine learning (bias/variance theory; innovation process in machine learning and AI).
- Analyze language, uncover contextual patterns, and produce insights from text and audio.
- Translate languages and summarize text
Phase 1: Natural Language Processing (NLP) – 12 months FREE Microsoft AZURE for Health
- NO-GOING – Text Analysis done in parallel on three LPBI’s Article Collections building a Proof of Concept performed by LPBI Group’s 2020/2021 Academic Internship in Medical Text Analysis (MTA) with Natural Language Processing (MTA-NLP): 9/2020 – 9/2021 – Academic INTERNSHIPS in LIFE SCIENCES, Medicine, Biological Sciences, Drug Discovery
- Inputs for Proof of Concept are the following three:
(1) Top 12 articles by views (all domains)
(2) Sixteen Cancer Articles representing 8 topics in Cancer Volume 1
(3) Sixteen Genomics Articles representing 21 chapters in Genomics Volume 1
Phase 2: Piloting the Proof of Concept on 4 of LPBI BioMed 16 volumes:
Cancer, Volume 1 & 2 and Genomics, Volume 1 & 2
- Expand applications of Microsoft AZURE and EXPERIMENT with Text Analysis The Wolfram Language
- Comparison of NLP results obtained for Microsoft AZURE and EXPERIMENT with Text Analysis The Wolfram Language
- Application on the ingress TEXT from:
Series C: e-Books on Cancer & Oncology
Volume 1:
Cancer Biology and Genomics for Disease Diagnosis
http://www.amazon.com/dp/B013RVYR2K
Volume 2:
Cancer Therapies: Metabolic, Genomics, Interventional, Immunotherapy and Nanotechnology in Therapy Delivery
http://www.amazon.com/dp/B071VQ6YYK
and
Series B: Frontiers in Genomics Research
Volume 1:
Genomics Orientations for Personalized Medicine
http://www.amazon.com/dp/B018DHBUO6
Volume 2:
Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology
https://www.amazon.com/dp/B08385KF87
Phase 3: Scaling up NLP, ML, AI to LPBI Group’s FOUR Corpuses Using LPBI’s Vendor of Choice:
- The Wolfram Solution for Biological Sciences
- The Wolfram Data Drop is an open service that makes it easy to accumulate data of any kind, from anywhere—setting it up for immediate computation, visualization, analysis, querying, or other operations
LPBI Group’s FOUR Corpuses
(1) All 6,000 Journal Articles
(2) 16 Books in Medicine
(3) 60 e-Proceedings & 36 Tweet Collections of TOP Global Medical and Biotech Conferences, 2013 – 2020
(4) Content Segmentation by other criteria for Narrow casting the content of the journal ontology, Categories of Research (N = 715). About 70% are related to Drug Discovery
Strategy #2: Blockchain Transactions and broadcasting to communities in the Health Care Sector – THE ONLY WAY TO MONETIZE our content by narrow casting to Health Care Communities: a Partner had lined them up and are willing to build the Front End
Strategy #3: Podcasts – will not be a Money maker – will be a Reputation Builder – very important in Pharmaceutical MEDIA
Strategy #4: Conversion e-Books to Audio and Articles to SoundCloud Audio files – Text to Audio [SEE New Yorker] – HAS POTENTIAL
Strategy #5: Joint venture with Biotech Accelerator for Drug Discovery:
Strategy #6: e-Books Translations into Japanese, Spanish, Russian
Initiative #4:
New Industry Partnerships
2.0 LPBI: 2021 and Beyond
In Details – the New Strategies: NS #1, #2, #3, #4, #5, #6
A. Explorations with a Leader NLP Vendor in Healthcare
2.0 LPBI – NS #1: Text Analysis with NLP, ML, AI
Proof of Concept in Cancer and Genomics is been developed for a Top Healthcare Insurer in UT.
- New cohort of INTERNS are joining LPBI on August 2020
- Text Analysis using Microsoft AZURE, NLP for Health – was tested and abandoned
- Proof of Concept will be design based on Text from the following THREE Sources and Using 12 Word Clouds for 2.0 LPBI’s HyperGraphDB construction: Biological Pathways, Therapeutics, Indications
WordCloud Visualization of LPBI’s Top Twelve Articles by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curators: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD, Aviva Lev-Ari, PhD, RN https://pharmaceuticalintelligence.com/2020/07/21/wordcloud-visualization-of-lpbis-top-twelve-articles-by-views-at-all-time-and-their-research-categories-in-the-ontology-of-pharmaceuticalintelligence-com/
WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN https://pharmaceuticalintelligence.com/2020/07/30/wordcloud-visualization-of-lpbis-top-sixteen-articles-on-cancer-in-eight-categories-and-by-views-at-all-time-and-their-research-categories-in-the-ontology-of-pharmaceuticalintelligence-com/
WordCloud Visualization of LPBI’s Top Sixteen Articles on GENOMICS by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curators: Stephen J. Williams, Aviva Lev-Ari, PhD, RN and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD https://pharmaceuticalintelligence.com/2020/07/30/wordcloud-visualization-of-lpbis-top-sixteen-articles-on-genomics-by-views-at-all-time-and-their-research-categories-in-the-ontology-of-pharmaceuticalintelligence-com/
B. Explorations with Blockchain Vendors in the Healthcare Sector
2.0 LPBI – NS #2: Blockchain Transaction Network Infrastructure – Partnership with World leader in the making.
The PLATFORM to sell Journal Articles, e-Books, e–Proceedings & Tweet Collections
- Work to start after Proof of Concept will be completed and All INSIGHTS will be used to narrowcast the articles by Research Categories. Using 12 Word Clouds for word-smithing the Message to be narrowcasted to communities of scientists on the Categories of Research covered per communities specialties and the Article Titles available for download for $30 each.
- Front end design and narrow casting to Research Foundry and Communities on Partner’s Transaction System
- Competitors in this space
In the Healthcare Sector
The top 10 competitors in Blockchain technology are:
AMC Health
Real-Time. Proven. Seamless.
AMC’s superior platform combines more than 17-years of hands-on clinical expertise, plus state-of-the-art technology providing real time patient data. Our platform is the only FDA Class II cleared care management platform, with multiple peer-reviewed studies and the ability to provide seamless connections that bridge the gap for care teams, members (patients) and payors.
Trapollo
Trapollo Converge
Secure, cloud-based, connected patient engagement — that extends care beyond the traditional walls of healthcare.
Trapollo Converge is a highly flexible and extensible virtual-care platform purpose-built for delivering care coordination and health monitoring. It provides intuitive and easy-to-use technology and a device-agnostic platform for clinicians, patients and family caregivers.
With its powerful digital engagement tools, telehealth capabilities and monitoring functions, Trapollo Converge connects its clients across the healthcare spectrum and patient populations to fulfill the true promise of Connected Health delivery.
Tactio Health Group
We digitize remote care for physician groups demanding scalable, secure and senior-friendly solutions.
We make RPM programs successful in North America with our pillar platform CareSimple, designed for physician groups of all sizes and their patients of any age. We also help integrate RPM solutions in other regulatory markets with CareSimple Franchise.
We build on the vast experience of over 4.5M Health App downloads in 17 languages, 100+ medical device integrations, and several prereimbursement RPM care models.
We strive to make our software and services simple so our customers can focus on care, patient compliance, clinical efficiency and outcomes.
We are collaborative and agile and we operate under the rigor of audited quality and security processes.
Vivify Health is transforming healthcare by replacing episodic approaches with the market’s most complete, patient-centered, and holistic connected care platform. Discover how we can help you launch and scale comprehensive, effective remote care programs that create exceptional clinical and financial ROI for chronic and post-acute care as well as wellness management.
Setting patients in the right direction for a continued path towards a healthy life is Vivify Health’s main priority. Using Vivify Pathways (our Remote Care Platform), you can choose from over 90 clinical and engagement pathways or combine them into thousands of programs. We don’t have one you need? You can use our intuitive drag-and-drop portal to create your own.
Scheduling and automating patient encounters to connect, engage, educate, guide, monitor and intervene gives you a great pathway towards success.
Start a population (or single patient) on a simple pathway. Based on patient events… interventions, escalations, and even additional pathway content can be automatically engaged for a patient, keeping populations on the right path with much less manual effort.
Accessible healthcare
A term often used interchangeably with telemedicine, telehealth or virtual healthcare, virtual care is the process of providing 24/7 real-time access to medical professionals via a mobile device – by voice, text or video.
In addition to diagnosing and treating common primary care ailments, virtual care also provides access to a broader range of non-clinical care services, such as mental health support, chronic disease management, and even specialist referrals and prescriptions.
https://www.telus.com/en/health/about-telus-health
VitalMobile is a Portuguese company who develops its activity exclusively in Remote Telemonitoring, and was a world pioneer in Professional Patient Monitoring.
VitalMobile, a “Spin Off” of UltraPonto, invests since 2003 its resources in improving the quality of life of patients. By helping each patient to better understand their condition, and support caregivers by giving them access to biometric data in real time and distance, has developed and implemented a new health model with proven benefits.
This model helps to improve the sustainability of the National Health Service and the profitability of private health providers to make the monitoring more efficient, patient complying with medical protocols and ensuring significant reduction of operating costs, travel, management, work organization and their prioritization.
https://www.vitalmobile.eu/en/content/company
INGENIUM HEALTHCARE ADVISORS is a team of seasoned Healthcare Delivery Improvement experts with healthcare experience ranging from 15 to 30 years.
Our ADVISORS enable providers to deliver the best care in the most efficient and cost-effective way.
We bring extensive experience in
– Project Management
– Business Analysis
– Quality Improvement
– Health IT
– Telehealth & Telemedicine
– Digital Health, Connected Health, and TeleHealth Strategy
We are Doctors, Nurses, Physician Assistants, Engineers, MBAs, and Healthcare Lawyers.
In partnership with forward-thinking healthcare leaders we develop Digital Health and Healthcare Delivery Improvement strategies. But we don’t stop there. We then implement the strategy by working with clinical, technical and administrative staff to design and build the unique solutions that improve the delivery of care.
Together we pursue one goal: Enabling Extraordinary Care.
https://ingeniumdigitalhealth.com/
Cardiocom, LLC
Medtronic, Inc. Drops $200 Million on Cardiocom LLC
Published: Aug 12, 2013
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Medtronic spends $200 million to acquire disease management company Cardiocom, the Wall Street Journal reports. Medtronic (NYSE:MDT) bought Cardiocom LLC for $200 million in cash in a bid to get into the disease management business, according to the Wall Street Journal. Chanhassen, Minn.-based Cardiocom makes devices aimed at helping to manage chronic conditions like diabetes or heart disease. The acquisition is aimed at putting Fridley, Minn.-based Medtronic in position to take advantage of the increasing focus on lowering healthcare costs, Medtronic’s U.S. president Mike Genau told the newspaper.
About the VSee Team
We’re more than a telemedicine platform. We’re people who believe in the power of telemedicine to save money, save lives, and improve healthcare. Our mission is to make telehealth an everyday experience, and we’re committed to helping our partners succeed at this. VSee serves over 2000 clients including GE, Shell, Trinity, DaVita, McKesson, Optum and NASA Space Station.
In the Beginning…
VSee was founded in 2008 by two Stanford PhD students, Dr. Milton Chen and Dr. Erika Chuang. They wanted to change how we worked by making remote work simple. Dr. Chen did his PhD research on the psychology of video communications, and also coded the original VSee video application. Dr. Chen has the privilege to deploy VSee for former President Obama’s Inauguration, the Navy Seals, and notables such as former Secretary of State Hillary Clinton, former UN Secretary-general Ban Ki-moon, Angelina Jolie, and Linkin Park. Dr. Chen has also been on numerous humanitarian and medical missions trips, personally traveling to Iraq twice, Syria twice, as well as Africa, Southeast Asia, and Latin America on many occasions.
Today we are a global tribe of designers and engineers passionate about using our skills to make a difference in the healthcare space. Telemedicine shouldn’t be another EMR nightmare, and doctors don’t need more apps they won’t use. We’re here to create a telemedicine experience that’s as simple and accessible as shopping online. That’s what we’re all about.
PROMINENT BLOCKCHAIN-AS-A-SERVICE PROVIDERS
- Dragonchain
- Factorm
- Bloq
- Skuchain
- LeewayHertz
- Altoros
- Appinventiv
- Fluence
- Innominds
SOURCE
https://builtin.com/blockchain/blockchain-as-a-service-companies
Competitors in Blockchain specializing in Healthcare include the following:
| Type | Private | |
| Founded | 2015 | |
| HQ | Colorado Springs, US | Map |
| Website | burstiq.com |
| Employees (est.) (Oct 2020) | 29 | (-3%) |
| Cybersecurity rating | B | More |
HQ
Princeton, US
Employees
2,378↑ 2% increase
We help healthcare organizations address complex challenges by seamlessly integrating Analytics, Technology, Operations and Medical expertise.
HQ
London, GB
Employees
50↓ 4% decrease
Doctify is a company operating an online platform that connects patients with the doctors.
HQ
Medley, US
Employees
10↓ 9% decrease
We are a young and driven biotech startup team based in Miami, Florida. Our aim is to create a cost-effective platform for regular health monitoring.
HQ
London, GB
Employees
1
Avalon AI is a company focusing on the automated derivation of brain biomarkers.
SOURCE
https://craft.co/burstiq/competitors
https://builtin.com/blockchain/blockchain-healthcare-applications-companies
C. Explorations with New Audio & Video Technologies for Podcasting
2.0 LPBI – NS #3: Audio-Video Podcasts Library
- Augmentation of the Work to be continued by Gail & Aviva & Dr. Williams & Irina
Using 12 Word Clouds for Topic Generation for to be initiated NEW Podcasts in 2021 and beyond
D. Explorations with Text to Audio Vendors
2.0 LPBI – NS #4: Conversion of LPBI’s e-Book Series into 16 AUDIO BOOKS and
Text to Audio for each Article (N = 6,000)
- Strategy will be presented on August 18, 2020 Zoom Monthly Meeting
E. Explorations with Synthetic Biology for Drug Discovery
2.0 LPBI – NS #5: Joint Venture : 2.0 LPBI (30%) and Biotech Accelerator (70%)
President of the Biotech Accelerator had proposed on 7/21/2020: https://pharmaceuticalintelligence.com/calendar/
- Usage of Lab Space and Services of ABI LAB for the purpose of:
- Synthetic Biology Research on Galectins, See Table, below
- 2.0 LPBI Research Team: Ofer Markman, PhD and Irina Robu, PhD and Meg Baker, PhD
F. Explorations with Translation Agencies in Foreign Languages
2.0 LPBI – NS #6: e-Books Translations into Japanese, Spanish, Russian
- Plan will be developed in 2021
More Details on 2.0 LPBI’s the New Strategies:
NS #1, #2, #3, #4, #5, #6
That section will be updated upon FINAL VENDOR SELECTION
NS #1: Text Analysis with NLP, ML, AI
THE PLAN; 4Q 2020 & 2021
NS #1: TEXT Analysis on our CONTENTS: NLP, ML, AI – INSIGHTS MEAN VALUE and Up-selling content = NEW WARES to be brought to the market
Phase 1: Natural Language Processing(NLP) – 12 months FREE Microsoft AZURE for Health
explored ans abandoned
Different NLP Vendor in the run
- Text Analysis done in parallel on three LPBI’s Article Collections building a Proof of Concept performed byLPBI Group’s 2020/2021 Academic Internship in Medical Text Analysis (MTA) with Natural Language Processing (MTA-NLP): 9/2020 – 9/2021 – Academic INTERNSHIPS in LIFE SCIENCES, Medicine, Biological Sciences, Drug Discovery
- Inputs for Proof of Concept are the following three:
(1) Top 12 articles by views (all domains) (2) Sixteen Cancer Articles representing 8 topics in Cancer Volume 1 (3) Sixteen Genomics Articles representing 21 chapters in Genomics Volume 1
Phase 2: Piloting the Proof of Concept on 4 of LPBI BioMed 16 volumes:
Cancer, Volume 1 & 2 and Genomics, Volume 1 & 2
- Expand applications of Microsoft AZURE and EXPERIMENT with Text Analysis The Wolfram Language
- Comparison of NLP results obtained for Microsoft AZURE and EXPERIMENT with Text Analysis The Wolfram Language
- Application on the ingress TEXT from:
Series C: e-Books on Cancer & Oncology
Volume 1:
Cancer Biology and Genomics for Disease Diagnosis
http://www.amazon.com/dp/B013RVYR2K
Volume 2:
Cancer Therapies: Metabolic, Genomics, Interventional, Immunotherapy and Nanotechnology in Therapy Delivery
http://www.amazon.com/dp/B071VQ6YYK
and
Series B: Frontiers in Genomics Research
Volume 1:
Genomics Orientations for Personalized Medicine
http://www.amazon.com/dp/B018DHBUO6
Volume 2:
Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology
https://www.amazon.com/dp/B08385KF87
Phase 3: Scaling up NLP, ML, AI to LPBI Group’s FOUR Corpuses Using LPBI’s Vendor of Choice:
- The Wolfram Solution for Biological Sciences
- The Wolfram Data Drop is an open service that makes it easy to accumulate data of any kind, from anywhere—setting it up for immediate computation, visualization, analysis, querying, or other operations
LPBI Group’s FOUR Corpuses
(1) All 6,000 Journal Articles
(2) 16 Books in Medicine
(3) 60 e-Proceedings & 36 Tweet Collections of TOP Global Medical and Biotech Conferences, 2013 – 2020
(4) Content Segmentation by other criteria for Narrow casting the content of the journal ontology, Categories of Research (N = 715). About 70% are related to Drug DIscovery
The Voice of Ofer Markman, PhD
In 2020 and beyond, 2.0 LPBI brings to the Table:
- An Interdisciplinary Team of Experts
- Deep Multiple Domains Knowledge
- Academic and Industry Recognition
- Remarkable e-Reputation on leading professional social media platforms, i.e., Twitter.com (The Leader for BioSciences Innovations announcements) and LinkedIn.com
- Global Expansive Business Connections
- Record of Unmatched Execution & Leadership
Dr. Ofer Markman
- Work to continue by All ACTIVE FIT Members in their expertise and ALL the INTERNS: current & new
- Using 12 Word Clouds for 2.0 LPBI’s HyperGraphDB construction: Biological Pathways, Therapeutics, Indications
- Using Microsoft AZURE – NLP for Health for the Proof of Concept
- For Cancer Volume 1 & 2 and Genomics Volume 1 & 2 – Comparison of Microsoft AZURE for Health with Text Analysis The Wolfram Language
On July 24, 2020, Dr. Williams on Methods to Improve the WordCloud images:
“So my suggestion would be actually to focus on the little words, which will give more insight into future targets, as the large words are well known. For example AKT, PI3K cancer is very well studied and dominates the literature. However, looking at some of the lesser ones, siRNA, targeting ,nuclear, complex, breast, targeted can one form into logical sentences which describe new avenues for research?” Also with the Word loud in media gallery readers can see a high definition image of it and then you can edit. Editing needs be done while on WordItOut.com platform before saved and exported.
On Sat, 8 Feb 2020 at 15:22 Aviva Lev-Ari <aviva.lev-ari@comcast.net> wrote:
UPDATED on 7/19/2020
The concept of HyperGraphDB and set of rules are needed to be created for the 1400 curations of Dr. Larry, more than half are about signaling pathways used in therapeutics using receptors.
THEN we will have the software for auto-independent semantic Text analysis of Dr. Larry’s UNIVERSE of articles – this was Dr. Williams great Idea.
(7/19/2020 – 5,875 (all articles) / 1400 (LHB’s Universe = 23.8%) of our IP in Journal articles.
Please read below, article and send me your comment on its relevance to our current search for a Partner with expertise in Machine Learning, Natural Language Processing, AI for text analysis.
https://www.wired.com/story/code-obsessed-novelist-builds-writing-bot-the-plot-thickens/
NS #2: Blockchain Infrastructure – The PLATFORM to sell Journal Articles, e-Books, e–Proceedings & Tweet Collections
15 EXAMPLES OF HOW BLOCKCHAIN IS REVIVING HEALTHCARE
BURSTIQ
Industry: Big Data, Cybersecurity, Software
Location: Colorado Springs, Colorado
What they do: BurstIQ’s platform helps healthcare companies safely and securely manage massive amounts of patient data. Its blockchain technology enables the safekeeping, sale, sharing or license of data while maintaining strict compliance with HIPAA rules.
Blockchain application: The company uses blockchain to improve the way medical data is shared and used.
Real-life impact: Because BurstIQ’s platform includes complete and up-to-date information about patients’ health and healthcare activity, it could help to root out abuse of opioids or other prescription drugs.
FACTOM
Industry: IT, Enterprise Software
Location: Austin, Texas
What they do: Factom creates products that help the healthcare industry securely store digital records on the company’s blockchain platform that’s accessible only by hospitals and healthcare administrators. Physical papers can be equipped with special Factom security chips that hold information about a patient and stored as private data that is accessible only by authorized people.
Blockchain application: Factom employs blockchain technology to securely store digital health records.
Real-life impact: In June of 2018, Factom got a grant of nearly $200,000 from the U.S. Department of Homeland Security to beta-test a platform aimed at integrating secure data from Border Patrol cameras and sensors in order to better understand the impacts of blockchain in “a realistic field environment.”
MEDICALCHAIN
Industry: Electronic Health Record, Medical
Location: London, England
What they do: Medicalchain’s blockchain maintains the integrity of health records while establishing a single point of truth. Doctors, hospitals and laboratories can all request patient information that has a record of origin and protects the patient’s identity from outside sources.
Blockchain application: Medicalchain’s blockchain-based platform maintains a record of origin and protects patient identity.
Real-life impact: In May of 2018, Medicalchain announced the release of MyClinic.com. A telemedicine platform, MyClinic enables patients to consult with their doctors via video and pay for those consultations with “MedTokens.”
GUARDTIME
Industry: Cybersecurity, Blockchain
Location: Irvine, California
What they do: Guardtime is helping healthcare companies and governments implement blockchain into their cybersecurity methods. The company was vital in helping implement blockchain in Estonia’s healthcare systems, and it recently signed a deal with a private healthcare provider in the United Arab Emirates to bring blockchain to its data privacy systems.
Blockchain application: Guardtime employs blockchain for cybersecurity applications, including healthcare.
Real-life impact: Guardtime recently teamed with Verizon Enterprise Solutions to deploy several platform services based on Guardtime’s Keyless Signature Infrastructure (KSI) Blockchain.
SIMPLYVITAL HEALTH
Industry: AI, Blockchain, Enterprise Software, Personal Health
Location: Watertown, Massachusetts
What they do: SimplyVital Health is making its decentralized technology available to the healthcare industry. It’s Nexus Health platform is an open source database that allows healthcare providers, on a patient’s blockchain, to access pertinent information. Open access to important medical information helps healthcare professionals coordinate medical efforts more quickly than traditional methods.
Blockchain application: SimplyVital uses blockchain to create an open source database so healthcare providers can access patient information and coordinate care.
Real-life impact: SimplyVital recently partnered with genemics and precision medicine company Shivom to form a Global Healthcare Blockchain Alliance that employs blockchain security to protect DNA sequencing data.
CORAL HEALTH RESEARCH & DISCOVERY
Industry: Healthcare, IT
Location: Vancouver, Canada
What they do: Coral Health uses blockchain to accelerate the care process, automate administrative processes and improve health outcomes. By inserting patient information into distributed ledger technology, the company connects doctors, scientists, lab technicians and public health authorities quicker than ever. Coral Health also implements smart contracts between patients and healthcare professionals to ensure data and treatments are accurate.
Blockchain application: Coral’s blockchain technology accelerates care, automates administrative processes and employs smart contracts between patients and doctors.
Real-life impact: According to Coral’s chief strategy officer Jeremy Mullin, the company is looking into the possibility of using a blockchain and the Smart on FHIR protocol “to let patients track their own health files.”
ROBOMED
Industry: Blockchain, Medicine
Location: Moscow, Russia
What they do: Robomed combines AI and blockchain to offer patients a single point of care. The company deploys chatbots, wearable diagnostic tools and telemedicine sessions to gather patient information and share it with the patient’s medical team. Robomeds Panacea platform engages patients into smart contracts that incentivize and lead them down the path to better health.
Blockchain application: Robomed uses blockchain to securely gather patient information and share it with a patient’s healthcare providers.
Real-life impact: The Taipei Medical University Hospital recently implemented blockchain technology, including Robomed’s network, to more securely store and share medical records.
PATIENTORY
Industry: Blockchain, Cybersecurity, Healthcare, IT
Location: Atlanta, Georgia
What they do: Patientory’s end-to-end encryption ensures that patient data is shared safely and efficiently. The company’s platform enables patients, healthcare providers and clinicians to access, store and transfer all important information via blockchain. Patientory helps the healthcare industry to move more quickly by housing all patient information under one roof.
Blockchain application: Patientory’s blockchain platform enables the secure storage and transfer of important medical information.
Real-life impact: Patientory recently hosted its first North American Blockchain in Healthcare Summitthat gathered hundreds of healthcare professionals to discuss and learn about blockchain-based healthcare applications.
CHRONICLED
Industry: Blockchain, Supply Chain Management
Location: San Francisco, California
What they do: Chronicled builds blockchain networks that demonstrate chain-of-custody. The networks help pharma companies make sure their medicines arrive efficiently, and they enable law enforcement to review any suspicious activity — like drug trafficking. In 2017, Chronicled created the Mediledger Project, a ledger system dedicated to the safety, privacy and efficiency of medical supply chains.
Blockchain application: Chronicle’d blockchain network is used to ensure the safe arrival and detailed review of drug shipments.
Real-life impact: According to the company, results from Chronicled’s recent MediLedger Project prove that its blockchain-based system “is capable of acting as the interoperable system for the pharmaceutical supply chain” and “can meet the data privacy requirements of the pharmaceutical industry itself.”
BLOCKPHARMA
Industry: Blockchain, Pharmaceuticals, Supply Chain
Location: Paris, France
What they do: Blockpharma offers a solution to drug traceability and counterfeiting. By scanning the supply chain and verifying all points of shipment, the company’s app lets patients know if they are taking falsified medicines With the help of a blockchain-based SCM system, Blockpharma weeds out the 15% of all medicines in the world that are fake.
Blockchain application: Through its app, the company’s blockchain-based system can help prevent patients from taking counterfeit medicines.
TIERION
Industry: Saas, Blockchain
Location: Mountain View, California
What they do: Tierion’s blockchain audits documents, records and medicines to keep a clear history of possession. The company uses timestamps and credentials to maintain proof of ownership throughout a medical supply chain.
Blockchain application: The company uses blockchain to maintain a clear possession history within medical supply chains.
Real-life impact: Tierion recently proposed a “multi-network coin” that could make Bitcoin more versatile and applicable.
CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC)
Industry: Government Agency, Healthcare, Security
Location: Atlanta, Georgia
What they do: The Centers for Disease Control and Prevention is looking into blockchain to monitor diseases in a supply chain-like manner. The U.S. Government agency says blockchain’s timestamps, peer-to-peer health reporting and data processing capabilities can help report disease outbreak in real-time. By studying the trail of reported outbreaks, scientists can find the origin of a disease and patterns that help suppress disease. The CDC might also employ blockchain to track the opioid epidemic.
Blockchain application: The CDC uses blockchain to monitor diseases and report outbreaks in real time.
Real-life impact: IBM is working with the CDC to develop a blockchain-based surveillance system so public health agencies can more effectively gather data about patients and prescriptions.
NEBULA GENOMICS
Industry: Biotechnology, Genetics
Location: Boston, Massachusetts
What they do:Nebula Genomics is using distributed ledger technology to eliminate unnecessary spending and middlemen in the genetic studying process. Pharmaceutical and biotech companies spend billions of dollars each year acquiring genetic data from third parties. Nebula Genomics is helping to build a giant genetic database by eliminating expensive middlemen and incentivizing users to safely sell their encrypted genetic data.
Blockchain application: The company uses blockchain to streamline the study of genetics and lower costs.
ENCRYPGEN
Industry: Blockchain, Data-Sharing
Location: Coral Springs, Florida
What they do: The EncrypGen Gene-Chain is a blockchain-backed platform that facilitates the searching, sharing, storage, buying and selling of genetic information. The company protects its users’ privacy by allowing only other members to purchase the genetic information using safe, traceable DNA tokens. Member companies can use the genetic information to build upon their genetic knowledge and advance the industry.
Blockchain application: The company’s blockchain platform makes it easier to search for, share, store and buy genetic information.
Real-life impact: EncrypGen plans to expand its user profile to include self-reported medical and behavioral data. According to company co-founder and CEO Dr. David Koepsell, it’s also working on integrating a blockchain payment and auditing platform as well as forming partnerships with testing companies, analytics software developers and others.
DOC.AI
Industry: AI, Blockchain, Medical, Software
Location: Palo Alto, California
What they do: Doc.ai uses machine intelligence, like AI, to decentralize medicine on the blockchain. Users can opt into the company’s platform to share their medical and genomic data with a community of scientists that use the data for predictive modeling. doc.ai saves no patient data. Once information is uploaded, encrypted on a blockchain and used in a trial, the data is wiped out in order to ensure security and privacy.
Blockchain application: The company’s employs machine intelligence (like AI) to decentralize medical data on the blockchain.
Real-life impact: The company recently partnered with health insurer Anthem tostudy the use of artificial intelligence in predicting the occurrence of allergic reactions.
-
Work to start upon completion of the Proof of Concept
Using 12 Word Clouds for word-smithing the Message to be narrowcasted to communities of scientists on the Categories of Research covered and the Article Titles available for download for $30 each.
- We wish to monetize the IP Asset Classes created in 1.0 LPBI: Class I, II, III, IV, V
- Foundry Research is the community of Scientists built by a Partner – they had presented on 7/21 at 3PM EST
The Voice of Stephen J. Williams, PhD, CSO, 1.0 LPBI
sjwilliamspa
The concept of combining HyperPad, WordCloud, and mind-mapping could be a powerful tool (or platform) in conjunction with a corpus of knowledge, i.e.,
- Dr. Bernstein’s sub corpus of knowledge here or
- Dr. Fauci’s corpus of knowledge obtained from Pubmed) then one can
- Maps the Mind of any KOL in any given area
https://pharmaceuticalintelligence.com/2018/04/10/electronic-scientific-agora-comment-exchanges-by-global-scientists-on-articles-published-in-the-open-access-journal-pharmaceuticalintelligence-com-four-case-studies/ In addition,
- The ability of blockchain technology to offer secure, ledgered, and recorded transfer of data has only started to be utilized for literature, although mainly for transfer of secure electronic records involving healthcare records or business and legal documents.
- The use of blockchain for the secure, ledgered transfer/access to biomedical literature would be a novel undertaking. This type of technology would enhance legitimate transfer of data (articles) [a chief goal of 2.0 LPBI] while preventing the illegitimate transfer of those articles by data trollers.
- This could actually enhance the mission of 2.0 LPBI to rapidly and openly disseminate information. Blockchain will also allow better data management more under the control of an entity which own the corpus and allow analysis in real time by third party algorithms, given access through blockchain of said corpus (Agora of knowledge).
- Electronic Scientific AGORA: Comment Exchanges by Global Scientists on Articles published in the Open Access Journal @pharmaceuticalintelligence.com – Four Case StudiesCurator and Editor-in-Chief: Journal and BioMed e-Series, Aviva Lev-Ari, PhD, RN
- blockchain may assist in ways to incentivize the creators of knowledge in a sort of a self sustaining ecosystem. This has been tried by many open access journals where reviewers for the journal are given credits to defray publication costs
- therefore Value of Effort = monetized Value ($)
- this maintains the integrity of effort, the integrity of work and actually enhances it.
- Through blockchain technology this can run automated and unbiased.
The Voice of Daniel Menzin:
“How Blockchain Technology can Assist 2.0 LPBI in monetizing IP Asset Classes created in 1.0 LPBI: Class I, II, III, IV, V”
1. Blockchain may be able to provide us with an organized way to keep track of each 30 dollar transaction. I would imagine their system would provide us with useful data as well which we can analyze like we’ve done with Twitter and WordPress.
2. Since Blockchain is a shared ledger, it can distribute data across sites, institutions, or countries. This would allow us to organize all of our IP assets and transact with our buyer digitally, requiring less work to be done by the buyer in developing our existing infrastructure for their purposes I would imagine.
3. It appears to me that Blockchain would improve the efficiency and ability to track our business transactions and documentation during our exit process. Blockchain claims to provide a shared digital medium for tracking the paperwork and agreements existing between two business parties. It is a shared, immutable ledger meaning that “it is a consensus of replicated, shared, and synchronized digital data geographically spread across multiple sites, countries, or institutions. Unlike with a distributed database, there is no central administrator.” It is immutable, meaning that the data cannot be changed once a consensus is reached (to my understanding). It seems like an automated digital system which serves to improve the organization and efficiency of business transactions by creating “a system” of sorts which organizes information related to these processes.
The Voice of Aviva Lev-Ari, PhD, RN:
“How Blockchain Technology can Assist 2.0 LPBI in monetizing IP Asset Classes created in 1.0 LPBI IP Asset Classes:
- I (Journal),
- II (e-Books),
- III (e-Proceedings+Tweet Collections),
- IV (Composition of Methods),
- V (Gallery of Biological Images)
These resources [1.0 LPBI: IP Asset Classes I, II, III, IV, V] could be accessed on a National level (Country x,y,z) or at the EU level or another geography (South East Asia) by
- All Life Science Incubators
- All Biotech Start ups
- All Life Sciences Departments in any Higher EducationInstitute
- All Medical Schools: Faculties using the content for curriculum development, Research Staff and Medical Students
- All High school students writing Honor Final thesis in Life Sciences
- All private individuals seeking knowledge in the Life Sciences & Medicine, Pharmaceutics and Health Care
- Private & Public interests can be served: the Biotech/Healthcare sectors, Education Sectors, and
- it can in parallel have a few business lines that are fully commercial for parties beyond Country x,y,z or the EU or another geography, i.e., Global and International NGOs such as Teva, IBM, GE Health, Siemens Healthineers, National’s HMOs can use the platform for Medical Doctors and Allied Health professionals continuing education using the contents of each of the three IP asset classes.
1. Blockchain may be able to provide us with a platform to narrowcast Word Cloud Images of2. 2.0 LPBI may be using Blockchain platform for the following functions:
- 1.0 LPBI Journal Articles to the Research Foundry Community: Article Title (Live Link), Views, Categories of Research and Word Cloud Images
- A platform for selling Journal Articles, Books, e-Proceedings and Tweet Collections
- A Global Transaction System (GTS) generating Account Receivables and an Immutable ledger
- Personalized Medicine,
- Workflow Optimization,
- High-Accuracy of 2.0 LPBI Article Buyer Directories,
- Collaborative Research,
- E-ID Programs,
- National health Record Networks,
- Health Information Exchanges,
- Enterprise Data Networks,
- Eligibility & Revenue Cycle,
- Innovation Sandboxes,
- Digital Therapeutics,
- Reporting on Clinical Research
3. 2.0 LPBI may be using Blockchain platform for NARROWCASTING content to Partners and Communities that a Leader in Blockchain Platforms specializing in Health Care had already put in place.
- We will narrowcast the Article WordClouds instead of the Article Abstracts, 12 examples are as presented below
- We will narrowcast the electronic Table of Contents (eTOCs) instead of the the Preface
- We will narrowcast the Tweet Collections to trigger interest in the entire e-Proceedings of a Conference
NS #3: Audio-Video Podcasts Library
- Augmentation of the Work to be continued by Gail & Aviva & Dr. Williams & Irina
Using 12 Word Clouds for Topic Generation for to be initiated NEW Podcasts in 2021 and beyond
Gail’s work:
Selected Projects:
1. Podcast Schedule https://pharmaceuticalintelligence.com/audio-podcasts/
Development Plan for e-VOICES Podcasting, 2019 – 2021*
https://pharmaceuticalintelligence.com/audio-podcasts/
| Podcast Interviewer | INTERVIEWEE(S) | Subject | Date | Audio/Video/
Narrator |
| Gail S. Thornton | Dr. Stephen J. Williams, Dr. Irina Robu & Dr. Aviva Lev-Ari | 3D BioPrinting in Medicine | 5/2019 | Audio |
| Gail S. Thornton | Prof. Feldman | Evolution Biology and Population Genetics | 3/17/2020 | Audio |
| Gail S. Thornton | Dr. Larry H. Bernstein, MD, FCAP | Life Memoirs in Clinical Pathology Told | 10/12/2020 | Audio
Narrator: Dr. S.J. Williams |
| Gail S. Thornton | Dr. Sudipta Saha | Research in Reproductive Technology | 11/7/2020 | Audio |
| Gail S. Thornton | Dr. Justin D. Pearlman, MD, PhD | Cardiac Imaging – Evolution of Diagnostic Methods | 4Q 2020 | Audio |
|
Gail S. Thornton |
Dr. Raphael Nir | From Big Pharma to Biotech Entrepreneurship | 2021 | Audio |
|
Gail S. Thornton |
Dr. Meg Baker | GlycoBiology in Practice | 2021 | Audio |
| Gail S. Thornton | Dr. Ofer Markman | Memories of
Procognia |
2021 | Audio |
| Gail S. Thornton | Dr. Irina Robu | AI & Tissue Engineering | 2021 | Audio |
|
Gail S. Thornton |
Dr. Williams |
Preferably 3rd party interviewer sourced AI & Genomics by Gail |
2021 | Audio |
| Gail S. Thornton | Dr. Aviva Lev-Ari | Preferably 3rd party interviewer sourced Curation & ML by Gail | 2021 | Audio |
Interview with Professor Marcus Feldman, Stanford University by Gail S. Thornton
https://pharmaceuticalintelligence.com/audio-podcasts/
Forthcoming
Gail’s Interview with Dr. Larry H. Bernstein, MA, FCAP
- A Narrated Version – Tribute to his life long Contributions to Medicine
- LHB lost his voice in thyroid cancer in 2016, since then on Medical LEAVE @LPBI as CSO and Emeritus, Board Member
and
- On 3/12/2015 – Dr. Williams posted
Podcast Review: Quiet Innovation Podcast on Obtaining $ for Your Startup
Reporter: Stephen J. Williams, Ph.D.
- On 1/25/2016 – Aviva posted
Launching LPBI’s, Fourth Line of Business (D): FIVE Podcast – Audio Series in BioMed
Curator: Aviva Lev-Ari, PhD, RN
- On 3/17/2016 – Aviva posted
CRISPR: A Podcast from Nature.com on Gene Editing
Reporter: Aviva Lev-Ari, PhD, RN
https://pharmaceuticalintelligence.com/2016/03/17/crispr-a-podcast-from-nature-com-on-gene-editing/
NS #4: Conversion of LPBI’s e-Book Series into AUDIO BOOKS
Strategy will be pursued in 2021
NS #5: Joint Venture : 2.0 LPBI and a Biotech Accelerator
President of the Biotech Accelerator proposed on 7/21/2020:
https://pharmaceuticalintelligence.com/calendar/
- Usage of Lab Space and Services of the Accelerator for the purpose of:
- Synthetic Biology Research on Galectins
- 2.0 LPBI Research Team: Ofer Markman, PhD and Irina Robu, PhD and Meg Baker, PhD
- Scientists love Synthetic Biology – designing drug molecules using Software – igem.org
https://igem.org/Software A repository of open source software tools. Community driven data exchange standards. Specific software frameworks built explicitly for synthetic biology.
- INTERNS are joining after Labor Day – they need to gain some LAB Flavor in return for working as Volunteers @LPBI projects: SEE
- 2020/2021 LPBI Plan for IT Projects & Reseach Projects – LPBI’s TASKS for Research Assistants & Associates
Galectins are carbohydrate-binding proteins that are involved in many physiological functions, such as inflammation, immune responses, cell migration, autophagy and signalling. They are also linked to diseases such as fibrosis, cancer and heart disease. How such a small family of only 15 members can have such widespread effects remains a conundrum. In this Cell Science at a Glance article, we summarise recent literature on the many cellular activities that have been ascribed to galectins. As shown on the accompanying poster, these include carbohydrate-independent interactions with cytosolic or nuclear targets and carbohydrate-dependent interactions with extracellular glycoconjugates. We discuss how these intra- and extracellular activities might be linked and point out the importance of unravelling molecular mechanisms of galectin function to gain a true understanding of their contributions to the physiology of the cell. We close with a short outlook on the organismal functions of galectins and a perspective on the major challenges in the field.
Table of Human Galectins [edit]
https://en.wikipedia.org/wiki/Galectin#Table_of_Human_Galectins
| Human galectin | Location | Function | Implication in disease |
|---|---|---|---|
| Galectin-1 | Secreted by immune cells such as by T helper cells in the thymus or by stromal cells surrounding B cells [7]Also found in abundance in muscle, neurons and kidney[1] | Negatively regulate B cell receptor activationActivate apoptosis in T cells[6] Suppression of Th1 and Th17 immune responses[7] Contributes to nuclear splicing of pre-mRNA[23] | Can enhance HIV infectionFound upregulated in tumour cells |
| Galectin-2 | Gastrointestinal tract [24] | Binds selectively to β-galactosides of T cells to induce apoptosis[24] | None found |
| Galectin-3 | Wide distribution | Can be pro- or anti-apoptotic (cell dependent)Regulation of some genes including JNK1 [7] Contributes to nuclear splicing of pre-mRNA[23] Crosslinking and adhesive properties In the cytoplasm, helps form the ULK1-Beclin-1-ATG16L1-TRIM16 complex following endomembrane damage[13] | Upregulation occurs in some cancers, including breast cancer, gives increased metastatic potentialImplicated in tuberculosis defense[13] |
| Galectin-4 | Intestine and stomach | Binds with high affinity to lipid rafts suggesting a role in protein delivery to cells[7] | Inflammatory bowel disease (IBD)[7] |
| Galectin-7 | Stratified squamous epithelium[7] | Differentiation of keratinocytesMay have a role in apoptosis and cellular repair mediated by p53[7] | Implications in cancer |
| Galectin-8 | Wide distribution | Binds to integrins of the extracellular matrix.[3] In the cytoplasm, alternatively binds to mTOR or forms the GALTOR complex with SLC38A9, LAMTOR1, and RagA/B[12] | Downregulation in some cancersImplicated in tuberculosis defense |
| Galectin-9 | KidneyThymus[6] Synovial fluid Macrophages | Functions as a urate transporter in the kidney [25]Induces apoptosis of thymocytes and Th1 cells[6][7] Enhances maturation of dendritic cells to secrete inflammatory cytokines. In the cytoplasm, associates upon lysosomal damage with AMPK and activates it[12] | Rheumatoid arthritisImplicated in tuberculosis defense[12][26] |
| Galectin-10 | Expressed in eosinophils and basophils | Essential role in immune system by suppression of T cell proliferation | Found in Charcot Leyden crystals in asthma |
| Galectin-12 | Adipose tissue | Stimulates apoptosis of adipocytesInvolved in adipocyte differentiation[7] | None found |
UPDATED on 1/6/2020 CURATIONS of Scientific basic research findings and clinical interpretation by EXPERTS —>> Curations were what LPBI Group created since 4/2012 —>> Curations are the value we bring to a potential acquirer in the Life Sciences, Medicine, pharmaceutical domain. —>> We did it in three channels for knowledge dissemination OF OUR COLLABORATIVE formulations: 1. One Article Format of Curation by Experts was replicated by collaborations with other team members >5,700 TIMES 2. Expert Editors created electronic Table of Contents (eTOCs) for our 1st e-Book published 6/2013. We REPLICATED the process on eTOCs creation by Expert Editors SIXTEEN TIMES, 12/28/2019, last volume placed on the Medicine & Life Sciences in Kindle Store – our Genomics Volume 2 on AI in Medicine 3. 4/2013 was first BioIT Aviva covered in real time and created the first e-Proceedings, Dr. Williams created Twitter Analytics for it, WE IMPROVED AND REPLICATED this process >60 TIMES
- These three CORPUSES are seeking Transfer of Ownership and monetization in 2020.
NS #6: e-Books Translations into Japanese, Spanish, Russian
- Plan for 2021 TBD
@@@@@ – OLD CONTENT
UPDATED on 11/18/2019 The Digital Age Gave Rise to New Definitions – New Benchmarks were born on the World Wide Web for the Intangible Asset of Firm’s Reputation: Pay a Premium for buying e-Reputation https://pharmaceuticalintelligence.com/2019/07/31/the-digital-age-gave-rise-to-new-definitions-new-benchmarks-were-born-on-the-world-wide-web-for-the-intangible-asset-of-firms-reputation-pay-a-premium-for-buying-e-reputation/ For @AVIVA1950, Founder, LPBI Group @pharma_BI: Twitter Analytics [Engagement Rate, Link Clicks, Retweets, Likes, Replies] & Tweet Highlights [Tweets, Impressions, Profile Visits, Mentions, New Followers] https://analytics.twitter.com/user/AVIVA1950/tweets https://pharmaceuticalintelligence.com/2019/08/06/twitter-analytics-engagement-rate-link-clicks-retweets-likes-replies-tweet-highlights-tweets-impressions-profile-visits-mentions-new-followers-for-aviva1950-founder-lpbi-group-ph/
UPDATED on 7/23/2019
Founder’s Vision
Dr. Aviva Lev-Ari, PhD, RN is an alumna of University of California, Berkeley, PhD’83. Dr. Lev-Ari was nominated for the 2019 Alumni of the Year Award followed by 2020 Campanile Excellence in Achievement Awards nomination forthcoming, 11/2019. August 2018-July 2021, Dr. Lev-Ari serves the Massachusetts Academies of Sciences (MAS) as Liaison to the Biotechnology and eScientific Publishing industries. She serves as Board member, Fellow, and Advisor to the Governing Board http://www.maacadsci.org. LPBI Group as a venture was launched in 4/2012 by Dr. Lev-Ari and she is leading it since its inception. These significant accomplishments were achieved inThe growth in all the three domains, above, took place during that period and led to her nomination for the 2018 Yidan Prize. [Nomination for 2018 Yidan Prize, recognition in the field of MEDICAL education: development of curation methodologies for scientific content – 2018 Nominee, Aviva Lev-Ari, PhD, RN https://pharmaceuticalintelligence.com/2018/10/21/nomination-for-2018-yidan-prize-recognition-in-the-field-of-medical-education-development-of-curation-methodologies-for-scientific-content-2018-nominee-aviva-lev-ari-phd-rn/] Dr. Aviva Lev-Ari is the Director and Founder of a pharmaceutical media and digital scientific publishing group called Leaders in Pharmaceutical Business Intelligence (LPBI) Group, which owns the intellectual property in three interrelated healthcare content products:
- Pharmaceutical (Biomed e-Series, 16 volumes in the frontiers of Life Sciences and Medicine, average volume size: 2,400 pages, 96,000 page downloads),
- Media (e-Proceedings of Biotech Conferences, 70 events covered, 2013 to Present) and
- electronic Scientific Publishing (Open Access Online Scientific Journal, 1.7 Million readers, ~5,700 articles)
These three IP Asset Classes represent a vast IP portfolio owned by LPBI Group. We are currently exploring in North America, Europe and Southeast Asia, prospective acquisition opportunities for these IP resources [vast content, digital printed products, platform, methods, methodologies and systems]. A prospective acquirer would be an establishment, a corporation or an institute that will be able to carry these IP resources forward under new ownership and new management, as a new company. Following the knowledge transfer phase, the current team can continue pursuing their expertise under the new ownership and the new management. This is a concept of an M&A. Alternatively, a sale outright of the portfolio of IP could be considered under certain terms and conditions. It is Dr. Aviva Lev-Ari’s belief that this newly to be established organizational entity would provide employment to dozens of Postdocs in the Life Sciences, who face a small number of Academic openings in the LIfe Sciences in the developed countries. It will attract Medical Doctors interested in writing clinical interpretations to basic life sciences primary research outcomes using the methodology of curation for scientific findings developed by Dr. Lev-Ari and her Team as demonstrated in the 5,700 articles in the Journal mentioned above which to date had attracted ~8000 comments by Scientist eReaders around the Globe using in search the +10,000 tags and the 670 categories of research which form the Ontology of the Journal. Following such a transaction, these three vast IP assets will be hosted on a Cloud Web Services platform architecture managed by the new ownership and offering to the Public the advantages of global accessibility [under terms and conditions]. These resources could be accessed on a National level (Country x,y,z) or at the EU level or another geography by
- IP Asset Class I.An on-line open access pharma scientific journal which has published about 5700 articles which have been read by over 1 1/2 million readers (1,640,034 as of 7/1/2019). http://pharmaceuticalintelligence.com
- IP Asset Class II.A series of 16 e-books in five medical specialities, including cardiovascular, genomics, cancer, immunology and precision medicine – these are available on Amazon https://lnkd.in/ekWGNqA
- IP Asset Class III. An electronic corpus of the proceedings of 70 top Global Biomed scientific and Medical conferences. https://pharmaceuticalintelligence.com/press-coverage/
Human Capital and the Content Creation Process
- All Life Science Incubators
- All Biotech Start ups
- All Life Sciences Departments in any Higher EducationInstitute
- All Medical Schools: Faculties using the content for curriculum development, Research Staff and Medical Students
- All High school students writing Honor Final thesis in Life Sciences
- All private individuals seeking knowledge in the Life Sciences & Medicine, Pharmaceutics and Health Care
- Private & Public interests can be served: the Biotech/Healthcare sectors, Education Sectors, and
- it can in parallel have a few business lines that are fully commercial for parties beyond Country x,y,z or the EU or another geography, i.e., Global and International NGOs such as Teva, IBM, GE Health, Siemens Healthineers, National’s HMOs can use the platform for Medical Doctors and Allied Health professionals continuing education using the contents of each of the three IP asset classes.
In House Business and Management Tool Development
- The two Board Members, Dr. Stephen J. Williams and Dr. Marcus W. Feldman are fully involved in venture’s decision making activities.
- The LPBI Group’s team members are all Experts, Authors, experienced Writers professing the Curation methodology applied for content creation in Translational Medicine from Life Sciences to bedside Medicine, Genomics, Bioinformatics, AI in Radiology and Pathology and Precision Medicine, Cancer, Cardiovascular diseases and Cardiac Imaging, Immunology, Infectious diseases, BioMedicine, Biotechnology, Pharmaco-therapy, Medical Technology and Health Care.
https://pharmaceuticalintelligence.com/2019-vista/
- The LPBI Group’s Business Team had developed an extensive business plan for the potential acquirers of these three IP asset classes. Twelve industries were identified. The Business Plan and the Opportunities Map are ready for perusal.
2013-2019, On the Medical & Scientific Bookshelf in Kindle Store: eReader Behaviors: Browsing, Page Downloads and Buying e-Books – LPBI Group’s BioMed e-Series, Royalties Payment Analysis
- Full documentation of Intangible and of Tangible assets is updated quarterly.
Dr. Lev-Ari is bringing to the table a business candidate for an acquisition of the Intellectual property vast portfolio – three asset classes for common access by the entire BIOTECH Industry in Country x,y,z or the EU or another geography. The leading Global Conference Organizers for Global audiences in Biotech would benefit from IP Class III, and make it a product they currently do not have. Dr. Lev-Ari is interested in finding half a dozen appropriate potential acquirers, preferably in several geographies, who would champion the technology, the infrastructure, and the contents in Health care to continue this amazing series of accomplishments in three Industries:
- The team developed a calculator for valuation of LPBI Group’s IP by contributing factors to value creation [in beta phase: IP-VAL-CALC]
- The Opportunities Map, the Business plan and a detailed document describing the technology and the pipeline of new products and Content as a Service (CAAS), all three can be used for design of new PowerPoint Presentations in different languages customized to each acquirer’s identified industry, within each of the 12 industries. A Presentation per industry, presented to several potential acquirers within each industry.
- Pharmaceutical (BioMed eBooks),
- Media (e-Proceedings) and
- electronic Scientific Publishing (Journal).
UPDATED on 2/10/2019 Leaders in Pharmaceutical Business Intelligence (LPBI) Group is an electronic scientific publishing venture that has developed platform architecture methodologies and business models of intellectual property development via scientific content creation by curation. These aspects of our intellectual property assist the e-Scientific Publishing Industry and scientific information users to mitigate the information explosion of scientific articles in the Life Sciences and Medicine and their inevitable immediate obsolescence. The work produced by LPBI Group is a team effort within the key domains of BioMed, BioTech, Pharmaco-therapy, MedTech, Health Care and the Life Sciences-Medicine connection. Our system technologies, which include platforms, methodologies and models, also include development of significant content materials. Additionally, this work can be replicated in many fields, i.e., Legal, Economics, Finance, International Relations, as examples of disciplines. It should be noted that all of LPBI’s material could, in principle, be translated into other languages. All members of our team have at least 10 years of experience in the life sciences area and have been trained to master the methodology of scientific curation used in our articles, in turn, if selected by experienced editors, these articles are targeted for inclusion in our books. The members of the team include senior MDs, MD/PhDs, FACC, FCAP, PharmDs and senior PhDs who expressed interest in medical writing and clinical interpretation of basic research, translational research and interpretation of clinical trials outcomes. Highly qualified content consultants are involved in each of the five e-series (senior MDs, MD/PhDs, and Professors) are engaged in the production of our curations. The topics for article curations and for the contents of the books we have created are carefully edited; I am the editor-in-chief and lead this multidisciplinary content compilation using my diverse areas of technical training and experience. Our intellectual property “IP” consists of three classes of assets as described in detail within live links in the below, listed article.
- First, the Journal, an ongoing journal of curated, current biomedical research;
- Second, the books, a collection of 16 volumes of e-books available via Amazon in five specialties of Medicine: Cardiovascular, Genomics, Cancer, Immunology and Precision Medicine; and
- Third, real-time curation of biotech and medical conferences yielding an e-Proceedings at the end of the conference in One-click operation.
These three IP asset classes are described in details with live links in eScientific Publishing a Case in Point: Evolution of Platform Architecture Methodologies and of Intellectual Property Development (Content Creation by Curation) Business Model https://pharmaceuticalintelligence.com/2019/02/04/escientific-publishing-a-case-in-point-evolution-of-platform-architecture-methodologies-and-of-intellectual-property-development-content-creation-by-curation-business-model/ LPBI’s business is scalable, and the skill set needed for curation of scientific findings for clinical interpretations, as well as in other disciplines can be augmented by appropriate training in the curation methodology to be offered to experts in many fields. We have shown that synergy among experts, authors and writers yields outstanding collaborations in producing our curations. There are many post-doctoral individuals in biotech industries and academia who can serve as experts, authors and writers in continuing LPBI’s operations, following appropriate onboarding. The link, above is a summary of six demonstrations that justify these claims. The list of six points is followed by an extensive description of these valuable attributes of LPBI IP. The table for POINT #4 presents a concise summary of the functions and forms of LPBI IP three asset classes. UPDATED on 12/4/2018
2019 Strategic Marketing of LPBI Group’s Intellectual Property: Strength & Markets
LPBI Group Vision
UPDATED on 4/2/2018
e-Scientific Publishing: The Competitive Advantage of a Powerhouse for Curation of Scientific Findings and Methodology Development for e-Scientific Publishing – LPBI Group, A Case in Point
UPDATED on 2/21/2016
We are in the Professional Services Sector: e-Scientific Information Creation and Intellectual Property Assets Management:
Subsidiary #1: electronic Scientific Media or Scientific Digital Media – LPBI
- Journal,
- BioMed eSeries,
- Real Time Conference Press,
- Audio-Podcast Series in Medicine
Subsidiary #1, LPBI, our Scientific Digital Media, is been managed to Plan for completion of milestones on 12/2016 – when it will be a candidate for M&A into the electronic Scientific Publishing Industry: Medical Publishers’ Directory – 171 publishing companies that publish Medical books, e-books, magazines. [ Page 1 of 18 ]
http://www.publishersglobal.com/directory/subject/medical-publishers/
Subsidiary #4: We are intermediaries for Commercialization, Licensing, Sales Outright of US Patents, representing Two inventors in Medical Devices
We are in 3D BioPrinting R&D & Drug Discovery R&D:
Subsidiary #3: R&D in 3D BioPrinting – FUNDING needs: $20Million [If VAR considered: $40Million]
Subsidiary #5: R&D in Drug Discovery – FUNDING needs: $20Million
We are in the Financial Transaction Sector
(No Securities Traded):
Subsidiary #2: Deals, Funding and Partnerships
MEDICAL DEVICES
- Representation of Alpha Szensors, Inc. – Programmable sensors nanocarbon tubed for FUNDING – $XMillion for Manufacturing
- Representation of ValveCure – Mitral Valve Repair Probe for M&A – $XMillion Sales
- Representation of Telerescue – individualized portable Defibrilator for aFIB and CHF Patients for FUNDING – $XMillion
PLATFORM – Pharmaceutical KnowledgeBase – Global Relational DB of Oncology Drugs and Clinical Trial – the only one in existence for M&A or Unencumbered Sales of Assets – Quote available
- Representation of New Medicine Inc.
INVENTIONS IN BIOLOGICS
- Representation of BioTerm Therapeutics – Two Drug Devices Colagenease infusion – OBGYN Drug Injection and Syringe apparatus for FUNDING $XMillion each one
- Representation of SBH Sciences, Inc. for FUNDING $X to $2XMillion – Brain Tumor drug
- Representation of Woodlands Pharmaceutics for FUNDING $X to $2XMillion – Liver Fibrosis Drug
Drug Screening Phase to identify IF GDE will represent the following IP:
1. Small Molecules: Inventions of Professor Yedgar, HUJI, Licensable from Yissum, Tech Transfer HUJI
2. Biologics: Inventions of Professor Tirosh, HUJI, Licensable from Yissum, Tech Transfer HUJI – Yossi’s Company
3. Technion Tech Transfer: T-cube – Initiation of Relations by GDE – PENDING
4. Weizmann Institute Tech Transfer: YEDA – Initiation of Relations by GDE – PENDING
Material below that point is OUTDATED
This section is under construction
Our Open Access Online Journal
http://www.pharmaceuticalIntelligence.com is a scientific, medical and business, multi-expert authoring environment for information syndication in several domains of Life Sciences, Medicine, Pharmaceutical and Healthcare Industries, BioMedicine, Medical Technologies & Devices. Scientific critical interpretations and original articles are written by PhDs, MDs, MD/PhDs, PharmDs, Technical MBAs as Experts, Authors, Writers (EAWs) on an Equity Sharing basis.Journal Content Descriptors on 2/18/2016
Date | Views to Date |# of articles |NIH Clicks |Nature Clicks| 02/18/2016 | 886,454 | 4,162 | 2,911 | 1,813 |
Our Competencies
- Deals, Partnerships and Funding for Early Stage Biologics and Medical Devices Start Ups
- Scientific Curations in Medicine and Life Sciences
- HealthCare Investor’s Corner
- BioMed e-Series of e-Books
- Scientific Delegations of US Patent Holders
- Real Time Coverage of Scientific and Biotech Conferences
MultiMedia Presence
- Twitter.com: http://twitter.com/pharma_BI
@pharma_BI
- FaceBook Page
http://www.facebook.com/LeadersInPharmaceuticalBusinessIntelligence
- Launchers of a Professional Group on LinkedIn
http://www.linkedin.com/groups?gid=4346921&trk=hb_side_g
- Company Page on LinkedIn
e-Book Titles by LPBI
For more information on Real-Time Conference Coverage and a full listing of Conferences Covered by LPBI please go to:
https://pharmaceuticalintelligence.com/press-coverage/ 
Leaders in Pharmaceutical Business Intelligence is a Holding Company of Six Ventures:
Venture Overview Updated in New Company Page on LinkedIn: Leaders in Pharmaceutical Business Intelligence – 3/7/2015 https://pharmaceuticalintelligence.com/2015/03/07/venture-overview-updated-on-new-company-page-on-linkedin-leaders-in-pharmaceutical-business-intelligence/
e-Publishing: Medicine, HealthCare, Life Sciences, BioMed, Pharmaceutical– Open Access Online Scientific Journal http://pharmaceuticalintelligence.com
BioMedical e-Books e-Series: Cardiovascular, Genomics, Cancer, BioMed, Patient Centered Medicine https://pharmaceuticalintelligence.com/biomed-e-books/
2013 e-Book on Amazon.com
Perspectives on Nitric Oxide in Disease Mechanisms, on Amazon since 6/2/12013
http://www.amazon.com/dp/B00DINFFYC
2015 e-Book on Amazon.com
1. Metabolic Genomics and Pharmaceutics, on Amazon since 7/21/2015
http://www.amazon.com/dp/B012BB0ZF0 2. Cancer Biology & Genomics for Disease Diagnosis, on Amazon since 8/11/2015 http://www.amazon.com/dp/B013RVYR2K
3. Genomics Volume One
4. Physiology, Genomics and Pharmaceutical
5. Cardiovascular, Volume Two: Co-Curation, Methodology
6. Cardiovascular Diseases, Volume Three: Etiology, Genetics and Genomics
7. Cardiovascular Diseases, Volume Four: Regenerative and Translational Medicine
8. Cancer Volume Two: Immunotherapy, Nanotechnology in drug delivery
2016 we need to FIND Editors for Two e-Books
– Genomics Volume Two on NGS – Dr. Williams and another Editor
– Patient Voice on Invasive Procedures – New Editor
2016, We will continue with
– Aviva will work with Larry on CVD 5: Pharmacology-Therapy,
– With Adam and Dr. Pearlman, on CVD 6: Cardiac Surgery and Interventional
– With Adam and Dr. Pearlman, on CVD 7: CV Imaging
– Dr. Pearlman alone:
Three CVD Hardcopy Volumes, 1-Etiology, 2-Diagnostics, 3-Therapies
- VENTURE #3:
International Scientific Delegations https://pharmaceuticalintelligence.com/scientific-delegation
- VENTURE #4:
Funding, Deals & Partnerships https://pharmaceuticalintelligence.com/joint-ventures/
Business Development Plan for LPBI
– investors in Shanghai, China for funding Biologics and Medical Devices (Wilferd van Opstal)
– investors in Switzerland to find an e-Publisher to buy the Journal and the e-Books (Gerard Loiseau)
– a 3D Printing Swiss company – RegenHU — to establish Partnerships with MIT, GE, J&J [Adam on P&G]
– Adam drafts Patents with Bill Zurn on implantable Cardiovascular device – I am discussing Zurn’s IP with investors in Shanghai and NYC
– I work with investors in NYC (Nicholas Hall, Private Wealth Management, Maxim Group LLC) on Deals, Funding and Partnerships
- VENTURE #5:
IP Invented HERE!
- VENTURE # 6:
Real Time PRESS Coverage International Biotech Conferences https://pharmaceuticalintelligence.com/press-coverage/
Funding, Deals & Partnerships
- Corporate Clients for our Services
- Funding Cardiovascular Medical Devices Development
- Funding Biologics Development
- Funding Diagnostics
- Funding Partnerships in IP Development
- M&A and Exit
- Targeting Penetration in New Markets for High Technology Products
- Management of Engineering Design of Prototypes Outsourcing
Our Growth Needs: Leaders in Pharmaceutical Business Intelligence
Our Business Portfolio
VENTURE #1:
e-Publishing: Medicine, HealthCare, Life Sciences, BioMed, Pharmaceutical
-
Open Access Online Scientific Journal
11/19/2014 – PRESS RELEASE — Over 500,000 Unique Site Visits reached by PharmaceuticalIntelligence.com Reported today by Leaders in Pharmaceutical Business Intelligence (LPBI) https://pharmaceuticalintelligence.com/2014/11/19/over-500000-unique-site-visits-reached-by-pharmaceuticalintelligence-con-reported-today-by-leaders-in-pharmaceutical-business-intelligence-lbpi/ http://pharmaceuticalintelligence.com
-
Scoop.it!.com
- http://www.scoop.it/t/cardiotoxicity
- http://www.scoop.it/t/cardiovascular-and-vascular-imaging
- http://www.scoop.it/t/cardiovascular-disease-pharmaco-therapy
VENTURE #2:
1. BioMedical e-Books e-Series: Cardiovascular, Genomics, Cancer, BioMed, Patient Centered Medicine
https://pharmaceuticalintelligence.com/biomed-e-books/
- Series A: e-Books on Cardiovascular Diseases
- Series B: Frontiers in Genomics Research
- Series C: e-Books on Cancer & Oncology
- Series D: e-Books on BioMedicine – Metabolomics, Immunology, Infectious Diseases
- Series E: Titles in the Strategic Plan for 2014-2015
2. on Amazon’s Kindle e-Books List since 6/2013
3. Plans for Volume 1,2,3 – Hardcover
- Cardiovascular Diseases: Causes, Risks and Management – Volume 1,2,3 – Hardcover
4. Schedule Plan for e-Publishing on Amazon.com
- Publishing on Amazon Kindle – SIX Volumes in 2015:
1. Metabolomics, Volume One 2. Genomics, Volume One 3. Cancer Volume One 4. Cardiovascular – Volume 2 5. Cardiovascular – Volume 3 6. Cardiovascular – Volume 4
- Publishing on Amazon Kindle – Four Volumes in 2016:
1. Physiology, PharmacoTherapy and Genomics: The Patient-centered Medicine Perspective 2. Cancer, Volume Two 3. Cardiovascular – Volume 5 4. Cardiovascular – Volume 6
VENTURE #3:
International Scientific Delegations https://pharmaceuticalintelligence.com/scientific-delegation/
- Shanghai, May 2015
- Barcelona, Spain, November 2015
- Amsterdam, May 2016
- Geneva, November 2016
VENTURE #4:
Funding, Deals & Partnerships
https://pharmaceuticalintelligence.com/joint-ventures/
- Corporate Clients for our Services
- Funding Cardiovascular Medical Devices Development
- Funding Biologics Development
- Funding Diagnostics
- Funding Partnerships in IP Development
- M&A and Exit
- Targeting Penetration in New Markets for High Technology Products
- Management of Engineering Design of Prototypes Outsourcing
VENTURE #5:
IP Invented HERE!
1. Development of a NEW Nitric Oxide monitor to Alpha Szenszor Inc. sensor portfolio. A concept for a low cost POC e-nose, capable of real time ppb detection of Cancer The Cancer Team at Leaders in Pharmaceutical Business Intelligence under the leadership of Dr. Williams 2. Development of a NEW Nitric Oxide monitor to Alpha Szenszor Inc. sensor portfolio. A concept for Inhaled Nitric Oxide for the Adult HomeCare Market – IP by Dr. Pearlman and Dr. A. Lev-Ari a. iknow iNO is i-kNOw – Inhaled Nitric Oxide for the HomeCare Market https://pharmaceuticalintelligence.com/2013/10/16/iknow-ino-is-i-know-inhaled-nitric-oxide-for-the-homecare-market/ b. electronic Book on Nitric Oxide by Nitric Oxide Team @ Leaders in Pharmaceutical Business Intelligence (LPBI) Perspectives on Nitric Oxide in Disease Mechanisms http://www.amazon.com/dp/B00DINFFYC c. The rationale and use of inhaled NO in Pulmonary Artery Hypertension and Right Sided Heart Failure Larry H. Bernstein 8/20/2012 d. Inhaled Nitric Oxide in Adults: Clinical Trials and Meta Analysis Studies – Recent Findings Aviva Lev-Ari, PhD, RN, 6/2/2013 e. Clinical Indications for Use of Inhaled Nitric Oxide (iNO) in the Adult Patient Market: Clinical Outcomes after Use, Therapy Demand and Cost of Care Aviva Lev-Ari, PhD, RN, 6/3/2013 3. Cancer Genomics for NEW product development in diagnosis and treatment of Cancer Patients using sensory technology with applications for Radiation Therapy – The Cancer Team at Leaders in Pharmaceutical Business Intelligence under leadership of Dr. Larry H Bernstein, MD, FCAP 4. Developing Mitral Valve Disease: MRI Methods and Devices for Percutaneous Mitral Valve Replacement and Mitral Valve Repair Augmentation of Patented Technology using RF – Dr. Pearlman’s IP Non-Hardware Mitral Annuloplasty – Dr. Justin D. Pearlman https://pharmaceuticalintelligence.com/joint-ventures/valvecure-llc/non-hardware-mitral-annuloplasty-dr-justin-d-pearlman/ 5. Novel Technology using MRI for Vascular Lesions, Tumors, Hyperactive Glands and non-Surgical Cosmetic Reconstruction – Dr. Pearlman’s IP http://pharmaceuticalintelligence.com/biomed-e-books/series-a-e-books-on-cardiovascular-diseases/httppharmaceuticalintelligence-combiomed-e-bookscardiovascular-diseases-causes-risks-and-management/cvd-business-affairs/mitral-valve-disease-mri-methods-and-devices/
VENTURE # 6:
PRESS Coverage of Conferences
https://pharmaceuticalintelligence.com/press-coverage/
This page has the following sub pages.
2012pharmaceutical
Amandeep Kaur
Aashir Awan, Phd
Adina Hazan
Alan F. Kaul, PharmD., MS, MBA, FCCP
alexcrystal6
anamikasarkar
apreconasia
aviralvatsa
David Orchard-Webb, PhD
danutdaagmailcom
Demet Sag, Ph.D., CRA, GCP
Daniel Menzin
Dror Nir
dsmolyar
evelinacohn
Gail S Thornton
Irina Robu
jayzmit48
jdpmd
jshertok
kellyperlman
Ed Kislauskis
larryhbern
Madison Davis
marzankhan
megbaker58
ofermar2020
Dr. Pati
pkandala
Rosalind Codrington, PhD
ritusaxena
Rick Mandahl
sjwilliamspa
stuartlpbi
Dr. Sudipta Saha
tildabarliya
zraviv06
zs22
[…] Vision […]
[…] Vision […]
Dear Dr. Lev-Ari,
Thank you so much for your invitation. I will be honoured to join your team of experts, authors, writers.
With friendly regards
Lilia
You are welcome, you can suggest to me what are the activities you wish to get involved with, any Venture above, can use your talent.
The concept of combining HyperPad, WordCloud, and mindmapping could be a powerful tool (or platform) in conjunction with a corpus of knowledge (let’s say Dr. Bernstein’s sub corpus of knowledge here or Dr. Fauci’s corpus of knowledge obtained from Pubmed) then one can Map the Mind of any KOL in any given area
The ability of blockchain technology to offer secure, ledgered, and recorded transfer of data has only started to be utilized for literature, although mainly for transfer of secure electronic records involving healthcare or business and legal documents. the use of blockchain for the secure, ledgered transfer/access to biomedical literature would be a novel undertaking. This type of technology would enhance legitimate tranfer of data (articles) {a goal of LPBI} while preventing the illegitimate transfer of those articles by data trollers.. this could actually enhance the mission of LPBI to rapidly and openly disseminate information. Blockchain will also allow better data management more under the control of an entity which own the corpus and allow analysis in real time by third party algorithms, given access through blockchain of said corpus (Agora of knowledge).
In addition, blockchain may assist in ways to incentivize the creators of knowledge in a sort ofself sustaining ecosystem. This has been tried by many open access journals where reviewers for the journal are given credits to defray publication costs
therefore Value of Effort = monetized Value ($)
This maintains the integrity of effort, the integrity of work and actually enhances it. through blockchain technology this can run automated and unbiased.
SINCE I AGREE 100% with your two comments – I moved them UP inside as The Voice of Dr. Williams – 1st Voice followed by Daniel’s and my own.
What’s Taking place i am new to this, I stumbled upon this I’ve found It absolutely useful and it has helped me out loads. I hope to give a contribution & help other customers like its aided me. Good job.
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