Compilation of References in Leaders in Pharmaceutical Intelligence about
proteomics, metabolomics, signaling pathways, and cell regulation
Curator: Larry H. Bernstein, MD, FCAP
Proteomics
- The Human Proteome Map Completed
Reporter and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/28/the-human-proteome-map-completed/
- Proteomics – The Pathway to Understanding and Decision-making in Medicine
Author and Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/06/24/proteomics-the-pathway-to-understanding-and-decision-making-in-medicine/
- Advances in Separations Technology for the “OMICs” and Clarification of Therapeutic Targets
Author and Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/10/22/advances-in-separations-technology-for-the-omics-and-clarification-of-therapeutic-targets/
- Expanding the Genetic Alphabet and Linking the Genome to the Metabolome
Author and Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/09/24/expanding-the-genetic-alphabet-and-linking-the-genome-to-the-metabolome/
- Synthesizing Synthetic Biology: PLOS Collections
Reporter: Aviva Lev-Ari
http://pharmaceuticalintelligence.com/2012/08/17/synthesizing-synthetic-biology-plos-collections/
Metabolomics
- Extracellular evaluation of intracellular flux in yeast cells
Larry H. Bernstein, MD, FCAP, Reviewer and Curator
http://pharmaceuticalintelligence.com/2014/08/25/extracellular-evaluation-of-intracellular-flux-in-yeast-cells/ - Metabolomic analysis of two leukemia cell lines. I.
Larry H. Bernstein, MD, FCAP, Reviewer and Curator
http://pharmaceuticalintelligence.com/2014/08/23/metabolomic-analysis-of-two-leukemia-cell-lines-_i/ - Metabolomic analysis of two leukemia cell lines. II.
Larry H. Bernstein, MD, FCAP, Reviewer and Curator
http://pharmaceuticalintelligence.com/2014/08/24/metabolomic-analysis-of-two-leukemia-cell-lines-ii/ - Metabolomics, Metabonomics and Functional Nutrition: the next step in nutritional metabolism and biotherapeutics
Reviewer and Curator, Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/22/metabolomics-metabonomics-and-functional-nutrition-the-next-step-in-nutritional-metabolism-and-biotherapeutics/ - Buffering of genetic modules involved in tricarboxylic acid cycle metabolism provides homeomeostatic regulation
Larry H. Bernstein, MD, FCAP, Reviewer and curator
http://pharmaceuticalintelligence.com/2014/08/27/buffering-of-genetic-modules-involved-in-tricarboxylic-acid-cycle-metabolism-provides-homeomeostatic-regulation/
Metabolic Pathways
- Pentose Shunt, Electron Transfer, Galactose, more Lipids in brief
Reviewer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/21/pentose-shunt-electron-transfer-galactose-more-lipids-in-brief/ - Mitochondria: More than just the “powerhouse of the cell”
Reviewer and Curator: Ritu Saxena
http://pharmaceuticalintelligence.com/2012/07/09/mitochondria-more-than-just-the-powerhouse-of-the-cell/ - Mitochondrial fission and fusion: potential therapeutic targets?
Reviewer and Curator: Ritu saxena
http://pharmaceuticalintelligence.com/2012/10/31/mitochondrial-fission-and-fusion-potential-therapeutic-target/ - Mitochondrial mutation analysis might be “1-step” away
Reviewer and Curator: Ritu Saxena
http://pharmaceuticalintelligence.com/2012/08/14/mitochondrial-mutation-analysis-might-be-1-step-away/ - Selected References to Signaling and Metabolic Pathways in PharmaceuticalIntelligence.com
Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/14/selected-references-to-signaling-and-metabolic-pathways-in-leaders-in-pharmaceutical-intelligence/ - Metabolic drivers in aggressive brain tumors
Prabodh Kandal, PhD
http://pharmaceuticalintelligence.com/2012/11/11/metabolic-drivers-in-aggressive-brain-tumors/ - Metabolite Identification Combining Genetic and Metabolic Information: Genetic association links unknown metabolites to functionally related genes
Author and Curator: Aviva Lev-Ari, PhD, RD
http://pharmaceuticalintelligence.com/2012/10/22/metabolite-identification-combining-genetic-and-metabolic-information-genetic-association-links-unknown-metabolites-to-functionally-related-genes/ - Mitochondria: Origin from oxygen free environment, role in aerobic glycolysis, metabolic adaptation
Author and curator:Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/09/26/mitochondria-origin-from-oxygen-free-environment-role-in-aerobic-glycolysis-metabolic-adaptation/ - Therapeutic Targets for Diabetes and Related Metabolic Disorders
Reporter, Aviva Lev-Ari, PhD, RD
http://pharmaceuticalintelligence.com/2012/08/20/therapeutic-targets-for-diabetes-and-related-metabolic-disorders/ - Buffering of genetic modules involved in tricarboxylic acid cycle metabolism provides homeomeostatic regulation
Larry H. Bernstein, MD, FCAP, Reviewer and curator
http://pharmaceuticalintelligence.com/2014/08/27/buffering-of-genetic-modules-involved-in-tricarboxylic-acid-cycle-metabolism-provides-homeomeostatic-regulation/ - The multi-step transfer of phosphate bond and hydrogen exchange energy
Curator:Larry H. Bernstein, MD, FCAP,
http://pharmaceuticalintelligence.com/2014/08/19/the-multi-step-transfer-of-phosphate-bond-and-hydrogen-exchange-energy/ - Studies of Respiration Lead to Acetyl CoA
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/18/studies-of-respiration-lead-to-acetyl-coa/ - Lipid Metabolism
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/15/lipid-metabolism/ - Carbohydrate Metabolism
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/13/carbohydrate-metabolism/ - Prologue to Cancer – e-book Volume One – Where are we in this journey?
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/04/13/prologue-to-cancer-ebook-4-where-are-we-in-this-journey/ - Introduction – The Evolution of Cancer Therapy and Cancer Research: How We Got Here?
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/04/04/introduction-the-evolution-of-cancer-therapy-and-cancer-research-how-we-got-here/ - Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/11/01/inhibition-of-the-cardiomyocyte-specific-kinase-tnni3k/ - The Binding of Oligonucleotides in DNA and 3-D Lattice Structures
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/05/15/the-binding-of-oligonucleotides-in-dna-and-3-d-lattice-structures/ - Mitochondrial Metabolism and Cardiac Function
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/04/14/mitochondrial-metabolism-and-cardiac-function/ - How Methionine Imbalance with Sulfur-Insufficiency Leads to Hyperhomocysteinemia
Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/04/04/sulfur-deficiency-leads_to_hyperhomocysteinemia/ - AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
Author and Curator: SJ. Williams
http://pharmaceuticalintelligence.com/2013/03/12/ampk-is-a-negative-regulator-of-the-warburg-effect-and-suppresses-tumor-growth-in-vivo/ - A Second Look at the Transthyretin Nutrition Inflammatory Conundrum
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/12/03/a-second-look-at-the-transthyretin-nutrition-inflammatory-conundrum/ - Overview of Posttranslational Modification (PTM)
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/29/overview-of-posttranslational-modification-ptm/ - Malnutrition in India, high newborn death rate and stunting of children age under five years
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/15/malnutrition-in-india-high-newborn-death-rate-and-stunting-of-children-age-under-five-years/ - Update on mitochondrial function, respiration, and associated disorders
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/08/update-on-mitochondrial-function-respiration-and-associated-disorders/ - Omega-3 fatty acids, depleting the source, and protein insufficiency in renal disease
Larry H. Bernstein, MD, FCAP, Curator
http://pharmaceuticalintelligence.com/2014/07/06/omega-3-fatty-acids-depleting-the-source-and-protein-insufficiency-in-renal-disease/ - Late Onset of Alzheimer’s Disease and One-carbon Metabolism
Reporter and Curator: Dr. Sudipta Saha, Ph.D.
http://pharmaceuticalintelligence.com/2013/05/06/alzheimers-disease-and-one-carbon-metabolism/ - Problems of vegetarianism
Reporter and Curator: Dr. Sudipta Saha, Ph.D.
http://pharmaceuticalintelligence.com/2013/04/22/problems-of-vegetarianism/
Signaling Pathways
- Introduction to e-Series A: Cardiovascular Diseases, Volume Four Part 2: Regenerative Medicine
Larry H. Bernstein, MD, FCAP, writer, and Aviva Lev- Ari, PhD, RN http://pharmaceuticalintelligence.com/2014/04/27/larryhbernintroduction_to_cardiovascular_diseases-translational_medicine-part_2/ - Epilogue: Envisioning New Insights in Cancer Translational Biology
Series C: e-Books on Cancer & Oncology
Author & Curator: Larry H. Bernstein, MD, FCAP, Series C Content Consultant
http://pharmaceuticalintelligence.com/2014/03/29/epilogue-envisioning-new-insights/ - Ca2+-Stimulated Exocytosis: The Role of Calmodulin and Protein Kinase C in Ca2+ Regulation of Hormone and Neurotransmitter Writer and Curator: Larry H Bernstein, MD, FCAP and Curator and Content Editor: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/12/23/calmodulin-and-protein-kinase-c-drive-the-ca2-regulation-of-hormone-and-neurotransmitter-release-that-triggers-ca2-stimulated-exocy - Cardiac Contractility & Myocardial Performance: Therapeutic Implications of Ryanopathy (Calcium Release-related Contractile Dysfunction) and Catecholamine Responses
Author, and Content Consultant to e-SERIES A: Cardiovascular Diseases: Justin Pearlman, MD, PhD, FACC
Author and Curator: Larry H Bernstein, MD, FCAP and Article Curator: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/08/28/cardiac-contractility-myocardium-performance-ventricular-arrhythmias-and-non-ischemic-heart-failure-therapeutic-implications-for-cardiomyocyte-ryanopathy-calcium-release-related-contractile/ - Role of Calcium, the Actin Skeleton, and Lipid Structures in Signaling and Cell Motility
Author and Curator: Larry H Bernstein, MD, FCAP Author: Stephen Williams, PhD, and Curator: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/08/26/role-of-calcium-the-actin-skeleton-and-lipid-structures-in-signaling-and-cell-motility/ - Identification of Biomarkers that are Related to the Actin Cytoskeleton
Larry H Bernstein, MD, FCAP, Author and Curator
http://pharmaceuticalintelligence.com/2012/12/10/identification-of-biomarkers-that-are-related-to-the-actin-cytoskeleton/ - Advanced Topics in Sepsis and the Cardiovascular System at its End Stage
Author and Curator: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/08/18/advanced-topics-in-Sepsis-and-the-Cardiovascular-System-at-its-End-Stage/ - The Delicate Connection: IDO (Indolamine 2, 3 dehydrogenase) and Cancer Immunology
Demet Sag, PhD, Author and Curator
http://pharmaceuticalintelligence.com/2013/08/04/the-delicate-connection-ido-indolamine-2-3-dehydrogenase-and-immunology/ - IDO for Commitment of a Life Time: The Origins and Mechanisms of IDO, indolamine 2, 3-dioxygenase
Demet Sag, PhD, Author and Curator
http://pharmaceuticalintelligence.com/2013/08/04/ido-for-commitment-of-a-life-time-the-origins-and-mechanisms-of-ido-indolamine-2-3-dioxygenase/ - Confined Indolamine 2, 3 dioxygenase (IDO) Controls the Homeostasis of Immune Responses for Good and Bad
Author and Curator: Demet Sag, PhD, CRA, GCP
http://pharmaceuticalintelligence.com/2013/07/31/confined-indolamine-2-3-dehydrogenase-controls-the-hemostasis-of-immune-responses-for-good-and-bad/ - Signaling Pathway that Makes Young Neurons Connect was discovered @ Scripps Research Institute
Reporter: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/06/26/signaling-pathway-that-makes-young-neurons-connect-was-discovered-scripps-research-institute/ - Naked Mole Rats Cancer-Free
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/06/20/naked-mole-rats-cancer-free/ - Amyloidosis with Cardiomyopathy
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/03/31/amyloidosis-with-cardiomyopathy/ - Liver endoplasmic reticulum stress and hepatosteatosis
Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2013/03/10/liver-endoplasmic-reticulum-stress-and-hepatosteatosis/ - The Molecular Biology of Renal Disorders: Nitric Oxide – Part III
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/11/26/the-molecular-biology-of-renal-disorders/ - Nitric Oxide Function in Coagulation – Part II
Curator and Author: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/11/26/nitric-oxide-function-in-coagulation/ - Nitric Oxide, Platelets, Endothelium and Hemostasis
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/11/08/nitric-oxide-platelets-endothelium-and-hemostasis/ - Interaction of Nitric Oxide and Prostacyclin in Vascular Endothelium
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/09/14/interaction-of-nitric-oxide-and-prostacyclin-in-vascular-endothelium/ - Nitric Oxide and Immune Responses: Part 1
Curator and Author: Aviral Vatsa PhD, MBBS
http://pharmaceuticalintelligence.com/2012/10/18/nitric-oxide-and-immune-responses-part-1/ - Nitric Oxide and Immune Responses: Part 2
Curator and Author: Aviral Vatsa PhD, MBBS
http://pharmaceuticalintelligence.com/2012/10/28/nitric-oxide-and-immune-responses-part-2/ - Nitric Oxide and iNOS have Key Roles in Kidney Diseases – Part II
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/11/26/nitric-oxide-and-inos-have-key-roles-in-kidney-diseases/ - New Insights on Nitric Oxide donors – Part IV
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/11/26/new-insights-on-no-donors/ - Crucial role of Nitric Oxide in Cancer
Curator and Author: Ritu Saxena, Ph.D.
http://pharmaceuticalintelligence.com/2012/10/16/crucial-role-of-nitric-oxide-in-cancer/ - Nitric Oxide has a ubiquitous role in the regulation of glycolysis -with a concomitant influence on mitochondrial function
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/09/16/nitric-oxide-has-a-ubiquitous-role-in-the-regulation-of-glycolysis-with-a-concomitant-influence-on-mitochondrial-function/ - Nitric Oxide and Immune Responses: Part 2
Author and Curator: Aviral Vatsa, PhD, MBBS
http://pharmaceuticalintelligence.com/2012/10/28/nitric-oxide-and-immune-responses-part-2/ - Mitochondrial Damage and Repair under Oxidative Stress
Author and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/10/28/mitochondrial-damage-and-repair-under-oxidative-stress/ - Is the Warburg Effect the cause or the effect of cancer: A 21st Century View?
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/10/17/is-the-warburg-effect-the-cause-or-the-effect-of-cancer-a-21st-century-view/ - Targeting Mitochondrial-bound Hexokinase for Cancer Therapy
Curator and Author: Ziv Raviv, PhD, RN 04/06/2013
http://pharmaceuticalintelligence.com/2013/04/06/targeting-mitochondrial-bound-hexokinase-for-cancer-therapy/ - Ubiquinin-Proteosome pathway, autophagy, the mitochondrion, proteolysis and cell apoptosis
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/10/30/ubiquinin-proteosome-pathway-autophagy-the-mitochondrion-proteolysis-and-cell-apoptosis/ - Ubiquitin-Proteosome pathway, Autophagy, the Mitochondrion, Proteolysis and Cell Apoptosis: Part III
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2013/02/14/ubiquinin-proteosome-pathway-autophagy-the-mitochondrion-proteolysis-and-cell-apoptosis-reconsidered/ - Biochemistry of the Coagulation Cascade and Platelet Aggregation – Part I
Curator and Author: Larry H Bernstein, MD, FACP
http://pharmaceuticalintelligence.com/2012/11/26/biochemistry-of-the-coagulation-cascade-and-platelet-aggregation/
Genomics, Transcriptomics, and Epigenetics
- What is the meaning of so many RNAs?
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/06/what-is-the-meaning-of-so-many-rnas/ - RNA and the transcription the genetic code
Larry H. Bernstein, MD, FCAP, Writer and Curator
http://pharmaceuticalintelligence.com/2014/08/02/rna-and-the-transcription-of-the-genetic-code/ - A Primer on DNA and DNA Replication
Writer and Curator: Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/29/a_primer_on_dna_and_dna_replication/ - Pathology Emergence in the 21st Century
Author and Curator: Larry Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/03/pathology-emergence-in-the-21st-century/ - RNA and the transcription the genetic code
Writer and Curator, Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/02/rna-and-the-transcription-of-the-genetic-code/ - Commentary on Biomarkers for Genetics and Genomics of Cardiovascular Disease: Views by Larry H Bernstein, MD, FCAP
Author: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/16/commentary-on-biomarkers-for-genetics-and-genomics-of-cardiovascular-disease-views-by-larry-h-bernstein-md-fcap/ - Observations on Finding the Genetic Links in Common Disease: Whole Genomic Sequencing Studies
Author an Curator: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/05/18/observations-on-finding-the-genetic-links/ - Silencing Cancers with Synthetic siRNAs
Larry H. Bernstein, MD, FCAP, Reviewer and Curator
http://pharmaceuticalintelligence.com/2013/12/09/silencing-cancers-with-synthetic-sirnas/ - Cardiometabolic Syndrome and the Genetics of Hypertension: The Neuroendocrine Transcriptome Control Points
Reporter: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/12/12/cardiometabolic-syndrome-and-the-genetics-of-hypertension-the-neuroendocrine-transcriptome-control-points/ - Developments in the Genomics and Proteomics of Type 2 Diabetes Mellitus and Treatment Targets
Larry H. Bernstein, MD, FCAP, Reviewer and Curator
http://pharmaceuticalintelligence.com/2013/12/08/developments-in-the-genomics-and-proteomics-of-type-2-diabetes-mellitus-and-treatment-targets/ - CT Angiography & TrueVision™ Metabolomics (Genomic Phenotyping) for new Therapeutic Targets to Atherosclerosis
Reporter: Aviva Lev-Ari, PhD, RN
http://pharmaceuticalintelligence.com/2013/11/15/ct-angiography-truevision-metabolomics-genomic-phenotyping-for-new-therapeutic-targets-to-atherosclerosis/ - CRACKING THE CODE OF HUMAN LIFE: The Birth of BioInformatics & Computational Genomics
Genomics Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/30/cracking-the-code-of-human-life-the-birth-of-bioinformatics-computational-genomics/ - Big Data in Genomic Medicine
Author and Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/12/17/big-data-in-genomic-medicine/ - From Genomics of Microorganisms to Translational Medicine
Author and Curator: Demet Sag, PhD
http://pharmaceuticalintelligence.com/2014/03/20/without-the-past-no-future-but-learn-and-move-genomics-of-microorganisms-to-translational-medicine/ - Summary of Genomics and Medicine: Role in Cardiovascular Diseases
Author and Curator, Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/01/06/summary-of-genomics-and-medicine-role-in-cardiovascular-diseases/
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