Composition of Methods (COM): Tool Factory for AI in Health Analytics – Components and Systems – IP Asset Class IV
Curator: Aviva Lev-Ari, PhD, RN
- Tool Factory” is a powerful metaphor: It positions COM (now 12 parts) as the manufacturing engine producing executable tools, workflows, and systems (e.g., Parts 10–12: multimodal Execution Infrastructure (EI), validation models, monetization exchanges). This directly counters competitors who are mostly platforms without LPBI’s proprietary “factory” for traceable, hybrid human+AI methods.
- “Components and Systems” captures the evolution: Parts 1–9 as foundational components, Parts 10–12 as integrated systems (execution infrastructure, validation, monetization).
- “AI in Health Analytics” keeps it domain-focused and ties to Grok’s causal reasoning/medal path—making COM the enabler of YYYs Healthcare Intelligence Hub (HIH/AJAUS).
- Impact on Narrative: Reinforces COM as the highest-value class ($xxx.xM+ uplift from Parts 9–12) and the true moat—no competitor has this depth of executable methodology.
- COM, Tool Factory for AI in Health Analytics – Components and Systems includes the following Methods:
Part 1: The “Curation Methodology” of Scientific Findings
Part 2: SOP on IT aspects of Data management on the Website
Part 3: Exploratory Protocols for Multimodal Foundation Model in Healthcare
3.1 Wolfram Code
3.2 Pilot Study with UK-based TOP NLP company, 2021
3.3 Grok 4.1
Part 4: Valuation Model for TEN IP Asset Classes
Slides for Appendices 22, 23
- 2026 Appendices to Every Slide N = 23 [password protected]
Part 5: Process workflows for six IP Asset Classes
Examples include: a curation article in the Journal, how to create an electronic Table of Content (eTOCs) for an e-Book, a Chapter in an e-Book, e-Proceedings, selection of Biological images and many more
Part 6: Media Gallery of >7,000 Biological Images
Samples by Image type are shown, below
Part 7: Royalties – Data collection on Amazon.com KDP
7.1 At the e-Book Level
7.2 At the e-Series Level
7.3 English Edition, Publishing Period, 6/2013 – 12/2021. Royalties, Book sale and Page downloads, 2013 to Present.
7.4 Spanish Edition, Publishing Period, 12/2022 – 1/2023. Royalties, 2023 to Present.
Slides for Appendices 22, 23
- 2026 Appendices to Every Slide N = 23 [password protected]
Part 8: IP Asset Class III: Aggregate Calculations of Views for e-Proceedings and Tweet Collections
8.1 Grand Total Views of e-Proceedings & Tweet Collections, 2013 – 2019
[Update for 2020-2025 – PENDING]
8.2 Archive of Real Time PRESS Coverage of Medical, Pharmaceutical and Biotech Conferences, 2013 to Present by (1) Press Reporter Name (2) Event Date(s) (3) Conference Name (4) e-Proceedings URL (5) Tweet Collection URL
[Data Collection – PENDING]
8.3 Marketing Channels for e-Proceedings & Tweet Collections – IP Asset Class III.
Part 9: Scoop.it Platform: Aviva Launched Three Journals since 2013 – a mini vault of N = 888 article titles.
- The plan is that in 2026 this Expert culled entries Data Set will be used to create “hybrid curations” aka “Human Guided AI Training Model for Content Creation” thus, Part 9 represents Data repository [data set] for development of a new Method in LPBI Group’s Composition of Methods (COM).
9.1 Journal launched by Aviva Lev-Ari on Cardiovascular and vascular imaging:
5.5K views (2018 data)
9.2 Journal launched by Aviva Lev-Ari on Cardiotoxicity:
693 views (2018 data)
9.3 Journal launched by Aviva Lev-Ari on PHARMACOTHERAPY:
4.3K views (2018 data)
To access these Journal one needs to subscribe on Scoop.it website.
Part 10: Multimodal Methods of Execution Infrastructure (EI) for AI Data Analyses and Exposition of the Analyses Results
- It presents the 1st Corporate Application of the Novel Method.
- It presents the Published Source(s).
10.1 Workflow for Dynamic Linkage and Transition between two Authoring Systems: LPBI Group’s WordPress.com Multi-Authors Authoring System and Microsoft PowerPoint product for Slide show presentation.
10.2 Method for Data Set Selection for Grok’s LLM & Causal Reasoning – Multimodal Data Set: Text & Images
10.3 Method for Data Set Selection for Grok’s LLM & Causal Reasoning – Multimodal Data Set: Audio, Text & Images
Part 11 – Validation Models for Execution Infrastructures – Library of Modules: Module 1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19
11.1 Validation Models for Data Set Selection Methods
11.2 Validation Model for Data Access Sequences prioritized by Executives for knowledge acquisition in Virtual Data Exposition about Acquisition Decision Making
Part 12 – Monetization Schedules for the Hybrid Model, Human & AI – Library of Systems: System 1, System 2, System 3, System 4
SYSTEM #1: Dynamic Intelligence Tokens Exchange [Stock in trade on the Exchange: Journal articles in 4 Domain Knowledge in Healthcare]
SYSTEM #2: Dynamic Image Exchange [Stock in trade on the Exchange: Images (Prior Art)]
SYSTEM #3: Dynamic Podcast Exchange [Stock in trade on the Exchange: Podcasts on Life Sciences Discoveries in the 21st Century]
SYSTEM #4: Dynamic Conference Content Exchange [Stock in trade on the Exchange: e-Proceedings & Tweet Collections Exchange or Dated Speakers & KOLs Quote
Part 13 -Training Data Sets for 15 SMALL Language Models: List of Articles in each Data Set and Methods for Content Augmentation for Transitioning SML to LLM
The output obtained from each of the 15 Subjects Matter from The List of Articles in 1 to 15 data sets is candidate for Content Augmentation.
List of Methods for Content Augmentation
13.1 – Method #1: Updates Output with Autonomous Journal Article Updating System (AJAUS)
13.2 – Method #2: Select additional articles from the List of Categories of Research that a HUMAN Expert MATCHED articles from List with Categories of Research in the List of Categories selected for the articles at hand, see URL, below
13.3 – Method #3: Scoop.it subscription ->>> Search Key words from articles and from Categories. Update the output with AJAUS
13.4 – Method #4: AI Modeling
13.4.1 NLP
13.4.2 Neural Network
13.4.3 Causal Reasoning: Text and Images
13.4.4 Grok Run Benchmark vs Wolfram+ChatGPT plug-in for 2026
13.4.5 Run Benchmark vs Grok’s choices of LLM Actor(s)
13.5 Transition from SLMs to Domain-aware Proprietary LLM – AI in Health
13.5.1 See List of Subjects Matter, below at Part 13.
Details and Itemization
Part 1: The “Curation Methodology” of Scientific Findings
Curation Methodology – Digital Communication Technology to mitigate Published Information Explosion and Obsolescence in Medicine and Life Sciences
Curator: Aviva Lev-Ari, PhD, RN
Innovations in electronic Scientific Publishing (eSP): Case Studies in Marketing eContent, Curation Methodology, Categories of Research Functions, Interdisciplinary conceptual innovations by Cross Section of Categories, Exposure to Frontiers of Science by Real Time Press coverage of Scientific Conferences
e-Scientific Publishing: The Competitive Advantage of a Powerhouse for Curation of Scientific Findings and Methodology Development for e-Scientific Publishing – LPBI Group, A Case in Point
The Methodology of Curation for Scientific Research Findings
@PharmaceuticalIntelligence.com – A Case Study on the LEADER in Curation of Scientific Findings
Curation of Scientific Content @Leaders in Pharmaceutical Business Intelligence (LPBI) Group, Boston
Scientific Curation Fostering Expert Networks and Open Innovation: Lessons from Clive Thompson
Cardiovascular Diseases and Pharmacological Therapy: Curations by Aviva Lev-Ari, PhD, RN, 2006 – 4/2018
Methodology for Conference Coverage using Social Media: 2014 MassBio Annual Meeting 4/3 – 4/4 2014, Royal Sonesta Hotel, Cambridge, MA
Cardiovascular Original Research: Cases in Methodology Design for Content Curation and Co-Curation
Other posts on this site related to Content Curation and Methodology include:
The growing importance of content curation
Data Curation is for Big Data what Data Integration is for Small Data
6 Steps to More Effective Content Curation
Stem Cells and Cardiac Repair: Content Curation & Scientific Reporting
Cancer Research: Curations and Reporting
Cardiovascular Diseases and Pharmacological Therapy: Curations
Exploring the Impact of Content Curation on Business Goals in 2013
conceived: NEW Definition for Co-Curation in Medical Research
Reconstructed Science Communication for Open Access Online Scientific Curation
Series A: e-Books on Cardiovascular Diseases
Series A Content Consultant:
Justin D Pearlman, MD, PhD, FACC
VOLUME TWO
Cardiovascular Original Research:
Cases in Methodology Design for Content Co-Curation
The Art of Scientific & Medical Curation
http://www.amazon.com/dp/B018Q5MCN8
Justin D Pearlman, MD, PhD, FACC
Larry H Bernstein, MD, FCAP
and
Aviva Lev-Ari, PhD, RN
Editor-in-Chief BioMed e-Series of e-Books
Leaders in Pharmaceutical Business Intelligence, Boston
avivalev-ari@alum.berkeley.edu
- Cardiovascular Diseases, Volume Two: Cardiovascular Original Research: Cases in Methodology Design for Content Co-Curation. On Amazon.com since 11/30/2015
Submission for Category: Book
Nomination of e-Book, Series A: Cardiovascular Diseases, Volume 2, Cases in Development of Scientific Curation Methodology
2016 Communication Awards Nomination Form Result #9143807
The National Academies of Sciences, Engineering, and Medicine
2016 Communication Awards for Excellence in Reporting and Communicating Science, Medicine and Engineering
Nomination Confirmation
Electronic Table of Contents (eTOCs) of Volume Two
Introduction to Volume Two
Part 1: The Methodology of Curation for Scientific Research Findings
1.1 The Methodology Explained
1.1.1 Curation by a Single Curator
1.1.2 Co-Curation by Several Experts, Authors, Writers
1.1.3 Editor’s Curation of an electronic Table of Contents (eTOCs) of an e-Book or a Hardcover Volume
1.2 The Creation Process of a Curation as an Alternative Model for Scientific Publishing
1.3 FIVE steps in the Creation Process of a Curation
1.3.1 CURATION and Co-CURATION of Scientific articles in conjunction with Experts, Authors, Writers critique and synthesis
1.3.2 Assembly of articles into e-Books using ONE of a Kind electronic Table of Contents (eTOCs) architecture
1.3.3 Assembly of e-Books into e-Series
1.3.4 Publishing of e-Series on Amazon.com
1.3.5 Distribution of e-Series to Professional Associations via their Internet website
1.4 Other Alternative Types to the Academic Publishing Model
1.5 Methodology of Curation Applied to Medical Research Findings
1.5.1 The Voice of Content Consultant on The Methodology of Curation
1.5.2 Curation is Uniquely Distinguished by the Historical Exploratory Ties that Bind
Part 2: SOP on IT aspects of Data management on the Website
- Data standardization Phase allowing for automation of the Article Classification remained INCOMPLETE.
- Requires advances Talent to pursue an autonomous system architecture allowing for (1) Classification (2) Content Update (3) populate each article with Updates
Part 3: Exploratory Protocols for Multimodal Foundation Model in Healthcare
3.1 Wolfram Code – Example from Genomics, Volume 3 in Spanish Edition
Five comments of note are repeated here from the Original Book and from the New Genre, Genomics Volume 2, PART A & PART C because of their significance:
Genomics, Volume 3 in Spanish Edition
Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology
https://www.amazon.com/dp/B0BRD8JXTL $155
Comment #1:
- No other book covers the same topics in a single volume
Comment #2:
- No other book incorporates 74 e-Proceedings created in real time by the Book’s authors and editors at conferences on Genomics
Comment #3:
- No other book incorporates four collections of Tweets representing quotes from speakers at global leading conferences on Genomics
Comment #4:
- No other book has 13 locations of Videos and Audio Podcasts that serve to enrich the e-Reader’s experience
Comment #5:
- No other book has 326 articles on the topics covered and included in the title of this Book: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology
The e-Reader is encouraged to read the Preface, the Introduction and the Epilogue to Genomics Volume 2
- Original Volume Two:
On Amazon.com since 12/28/2019
https://www.amazon.com/dp/B08385KF87
AND
the e-Reader is encouraged to continue to Genomics Volume 1
Genomics Orientations for Personalized Medicine
VOLUME ONE
On Amazon.com since 23/11/2015
http://www.amazon.com/dp/B018DHBUO6
NEW GENRE Genomics, Volume Three:
Results of Medical Text Analysis with Natural Language Processing (NLP): Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS
https://www.amazon.com/dp/B0BRD8JXTL
Results of Medical Text Analysis with Natural Language Processing (NLP): Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, … de la investigación genómica Book 3) Kindle Edition
by Madison Davis (Author), Aviva Lev-Ari (Editor), Stephen J. Williams (Editor), Marcus W. Feldman (Editor) Format: Kindle Edition
Serie B: Fronteras de la investigación genómica
(3 book series) Kindle Edition
by Larry H. Bernstein (Author) , Stephen J. Williams (Author) , Sudipta Saha (Author) , Ritu Saxena (Author) , Tilda Barliya (Author) , Anamika Sarkar (Author) , Marcus W. Feldman (Author) , Demet Sag (Author) , Prabodh kandala (Author) , Larry H. Bernstein (Author) , Aviva Lev-Ari (Author) , Madison Davis (Author)
https://www.amazon.com/dp/B0BQGZYZVT?binding=kindle_edition&ref=dbs_dp_rwt_sb_pc_tukn
Appendix to this volume – Wolfram Code
- for Hypergraph Plots &
- for Tree Diagram Plots
NLP Code writing for 7/8 Parts 1,2,3,4,5,7,8
[No Code for Part 6 in Volume 3]
by
Madison Davis
Code used in production of Hyper-graph Plots at the Book Part Level
| Hyper-
graph Plot #1
for 1.1.1 based on 16 articles & on 14 keywords |
wordSheet ={
protein,cancer,dna,gene,genes,rna,survival,immune,tumor,research,patients,human, genome,expression }; topN = Length[wordSheet]; words = {}; For[i = 1, i <= topN, i++, words = Append[words, ToString[wordSheet[[i]]]]]; Print[words]; maxN = 3; broadTerms = {}; words1 = {}; words2 = {}; For[i = 1, i <= topN, i++,If[Length[Position[WordData[], Extract[words, i]]] > 0, broadTerms = Append[broadTerms, Flatten[Values[WordData[Extract[words, i], “BroaderTerms”]]]]; words1 = Append[words1, Extract[words, i]], words2 = Append[words2, Extract[words, i]]]]; For[i = 1, i <= Length[broadTerms], i++, If[Length[broadTerms[[i]]] > maxN, broadTerms[[i]] = broadTerms[[i]][[1 ;; maxN]]]];
edgeList = {}; edgeList = Append[edgeList,Prepend[words1, “”]] ; For[i = 1, i <= Length[words1], i++, edgeList = Append[edgeList, Append[broadTerms[[i]], words1[[i]]]]]; ResourceFunction[“HypergraphPlot”][edgeList, VertexSize -> 0.01, VertexLabels -> Automatic, PlotTheme -> “Detailed”, SubsetEdge -> False, SubsetBoundaryScale -> 7, VertexStyle -> Red,”BaseLayout” -> “RadialEmbedding”,”SubsetEdgeStyle” -> ColorData[100, “ColorList”]] |
| Hypergraph Plot #2
for 1.1.2 based on 17 articles & on 12 keywords |
wordSheet ={
cancer,mutations,patients,gene,disease,genetic,mutation,data,clinical,tumor,genes, protein }; topN = Length[wordSheet]; words = {}; For[i = 1, i <= topN, i++, words = Append[words, ToString[wordSheet[[i]]]]]; Print[words]; |
Code used in production of Tree Diagram Plots
| Tree Diagram Plot #1
for 1.1.1 based on 16 articles & on 14 keywords |
wordSheet ={
protein,cancer,dna,gene,genes,rna,survival,immune,tumor,research,patients,human, genome,expression }; topN = Length[wordSheet]; words = {}; For[i = 1, i <= topN, i++, words = Append[words, ToString[wordSheet[[i]]]]]; Print[words]; maxN = 3; broadTerms = {}; words1 = {}; words2 = {}; For[i = 1, i <= topN, i++,If[Length[Position[WordData[], Extract[words, i]]] > 0, broadTerms = Append[broadTerms, Flatten[Values[WordData[Extract[words, i], “BroaderTerms”]]]]; words1 = Append[words1, Extract[words, i]], words2 = Append[words2, Extract[words, i]]]]; For[i = 1, i <= Length[broadTerms], i++, If[Length[broadTerms[[i]]] > maxN, broadTerms[[i]] = broadTerms[[i]][[1 ;; maxN]]]];
edgeList = {}; For[i = 1 , i <= Length[broadTerms], i++, edgeList = Append[edgeList, broadTerms[[i]]]]; For[i = 1 , i <= Length[broadTerms], i++, For[j = 1, j <= Length[edgeList[[i]]], j++, edgeList[[i]][[j]] = words1[[i]] -> edgeList[[i]][[j]]]]; For[i = 1 , i <= Length[words1], i++, edgeList = Append[edgeList, {“Chapter 1.1.1” -> words1[[i]]}]]; TreePlot[Flatten[edgeList], VertexSize -> 0.1, VertexLabels -> Automatic] |
| Tree Diagram Plot #2
for 1.1.2 based on 17 articles & on 12 keywords |
wordSheet ={
cancer,mutations,patients,gene,disease,genetic,mutation,data,clinical,tumor,genes, protein }; topN = Length[wordSheet]; words = {}; For[i = 1, i <= topN, i++, words = Append[words, ToString[wordSheet[[i]]]]]; Print[words]; |
3.3 Grok 4.1
- Exploratory Protocol for Comparison of NLP to LLM on Same Oncology Slice
Curators: Aviva Lev-Ari, PhD, RN and Stephen J. Williams, PhD, KOL on Cancer & Oncology
- 2025 Grok 4.1 Causal Reasoning & Multimodal on Identical Proprietary Oncology Corpus: From 673 to 5,312 Novel Biomedical Relationships: A Direct Head-to-Head Comparison with 2021 Static NLP – NEW Foundation Multimodal Model in Healthcare: LPBI Group’s Domain-aware Corpus Transforms Grok into the “Health Go-to Oracle”
Authors:
- Stephen J. Williams, PhD (Chief Scientific Officer, LPBI Group)
- Aviva Lev-Ari, PhD, RN (Founder & Editor-in-Chief Journal and BioMed e-Series, LPBI Group)
- Grok 4.1 by xAI
- Authentic Relevance of LPBI Group’s Portfolio of IP as Proprietary Training Data Corpus for AI Initiatives at Big Pharma
Curators: Aviva Lev-Ari, PhD, RN and Stephen J. Williams, PhD
- Generative AI Providers: Open Source and Closed source, @Google’s JAX AI stack versus @xAI @Grok
Curator: Aviva Lev-Ari, PhD, RN
Part 4: Valuation Model for TEN IP Asset Classes
Valuation Models per Ten Digital IP Asset Classes in LPBI Group’s Portfolio of IP
Curator: Aviva Lev-Ari, PhD, RN
Part 5: Process Workflows for Six IP Asset Classes
Examples include: a curation article in the Journal, how to create an electronic Table of Content (eTOCs) for an e-Book, a Chapter in an e-Book, e-Proceedings, selection of Biological images and many more.
CONTENT CREATION PROCESS WORKFLOW DIAGRAMS for Five of the TEN LPBI IP ASSET CLASSES
LPBI’s value chain from data to knowledge for the Knowledge workers in the Life Sciences and for the Consumers of Medical and Healthcare-related contents
These are the processes that LPBI’s team of experts employ to convert information into valuable knowledge
Composition of Methods: Process Workflows
IP Asset Class I: Journal Articles
New Number Updates 12/27/2025
Views 2,522,657; Visitors 1,560,952; Posts 6,275;
tags: >10,xxx; Comments: >7,4yy
[Old Numbers: 11/23/2020]
IP Asset Class II: e-Books in Medicine
Updated on 12/27/2025
English Edition: 18 Volumes in 17 Books + Bundles: 5 e-Series:
Series A, 6 volumes
Series B, 2 volumes
Series C, 2 volumes
Series D, 3 volumes: Volume 1, Volume 2 & 3, Volume 4
Series E, 4 volumes
Spanish Edition: 19 Volumes in 19 Books + Bundles: 5 e-Series:
Series A, 6 volumes
Series B, 3 volumes
Series C, 2 volumes
Series D, 4 volumes, Volume 1,2,3,4
Series E, 4 volumes
Old Data: 11/13/2020
Asset Class III: e-Proceedings of Biotech & Medical Conferences & Tweet Collections
IP Asset Class IV: Portal Launch Method
A Case in Point: Coronavirus Portal – a case of portal launch in 8 hours, 3/14/2020
IP Asset Class X: e-Voices Audio Podcasts –
A Library of Scientists Biographies
IP Asset Class V: Media Gallery of >7,000 Biological Images
The entire Media Gallery needs to be classified into Categories of Images, i.e., Type of Images
Classification Methods for Biological Images by Type, see examples, below, Part 6
Type 1: Analytics
Type 2: Word Clouds: AI in Medical Text Analysis with NLP
Type 3: Biological images
Type 4: People of Note
Type 5: Cover Pages of Books Published by LPBI Group.
Type 6: Genomics Research (mRNA) and Drug Activity
Part 6: Image Type: Classification of Items in the Media Gallery of >7,000 Biological Images
IP Asset Class V: Biological Images – Image Type Examples
The entire Media Gallery needs to be classified into types. Below, we feature 6 types by examples:
- Type 1: Analytics
- Type 2: Word Clouds: AI in Medical Text Analysis with NLP
- Type 3: Biological images
- Type 4: People of Note
- Type 5: Cover Pages of Books Published by LPBI Group.
- Type 6: Genomics Research (mRNA) and Drug Activity
Type 1: Analytics
[Graphs and Text]
Number of drug approvals by regulatory agency. Source: Yan Y, Guo X, Li Z, Shi W, Long M, Yue X, Kong F, Zhao Z. New Drug Approvals in China: An International Comparative Analysis, 2019-2023. Drug Des Devel Ther. 2025 Apr 3;19:2629-2639. doi: 10.2147/DDDT.S514132.
Type 2: Word Clouds: AI in Medical Text Analysis: NLP statistical algorithm
[Text & Image]
Imaged uploaded to Gallery on December 13, 2022
Type 3: Biological images
[Image and Text]
Type 4: People of Note
Professor Allan Pred, Advisor of Aviva Lev-Ari, PhD, RN at University of California, Berkeley,
9/1978 – 12/1983, Berkeley, California.
Aviva Lev-Ari, 9/1978, Picture on StudentID at UC, Berkeley, 1st year in doctoral program. Dissertation filed with Graduated Division, 12/1983.
Degree earned: UC, Berkeley, PhD’83.
Dr. Zelig Eshhar, A Founding Father of CAR-T cell Immunotherapy passed away on 7/4/2025
Type 5: Cover Pages of Books Published by LPBI Group [N = 48]
[Image and Text]
Type 6: Genomics Research (mRNA) and Drug Activity
[Image and Text]
Fig. 2. Chronic exposure to degraders induces MDR1 expression and drug efflux activity.
(A) ABCB1 mRNA levels in parental and degrader-resistant cell lines as determined by qRT-PCR. Data are means ± SD of three independent experiments. ***P ≤ 0.001 by Student’s t test.
(B) Immunoblot analysis of MDR1 protein levels in parental and degrader-resistant cell lines. Blots are representative of three independent experiments. (C to E) Immunofluorescence (“IF”) microscopy of MDR1 protein levels in A1847 dBET6-R
(C), SUM159 MZ1-R
(D), and Thal-R A1847 cells
(E) relative to parental cells. Nuclear staining by DAPI. Images are representative of three independent experiments. Scale bars, 100 μm.
(F) Drug efflux activity in A1847 dBET6-R, SUM159 MZ1-R, and Thal-R A1847 cells relative to parental cells (Par.) using rhodamine 123 efflux assays. Bars are means ± SD of three independent experiments. ***P ≤ 0.001 by Student’s t test.
(G) Intracellular dBET6 levels in parental or dBET-R A1847 cells transfected with a CRBN sensor and treated with increasing concentrations of dBET6. Intracellular dBET6 levels measured using the CRBN NanoBRET target engagement assay. Data were analyzed as % of DMSO control, presented as means ± SD of three independent assays. *P ≤ 0.05, **P ≤ 0.01, and ***P ≤ 0.001 by Student’s t test. (H and I) FISH analysis of representative drug-sensitive parental and drug-resistant A1847
(H) and SUM159
(I) cells using ABCB1 and control XCE 7 centromere probes. Images of interphase nuclei were captured with a Metasystems Metafer microscope workstation, and the raw images were extracted and processed to depict ABCB1 signals in magenta, centromere 7 signals in cyan, and DAPI-stained nuclei in blue. (J and K) CpG methylation status of the ABCB1 downstream promoter (coordinates: chr7.87,600,166-87,601,336) by bisulfite amplicon sequencing in parent and degrader-resistant A1847
(J) and SUM159
(K) cells. Images depict the averaged percentage of methylation for each region of the promoter, where methylation status is depicted by color as follows: red, methylated; blue, unmethylated. Schematic of the ABCB1 gene with the location of individual CpG sites is shown. Graphs are representative of three independent experiments. (L and M) Immunoblot analysis of MDR1 protein levels after short-term exposure [for hours (h) or days (d) as indicated] to BET protein degraders dBET6 or MZ1 (100 nM) in A1847
(L) and SUM159
(M) cells, respectively. Blots are representative of three independent experiments. (N to P) Immunoblot analysis of MDR1 protein levels in A1847 and SUM159 cells after long-term exposure (7 to 30 days) to BET protein degraders dBET6
(N), Thal SNS 032
(O), or MZ1
(P), each at 500 nM. Blots are representative of three independent experiments. (Q and R) Immunoblot analysis of MDR1 protein levels in degrader-resistant A1847
(Q) and SUM159
(R) cells after PROTAC removal for 2 or 7 days. Blots are representative of three independent experiments. Related data are in fig. S2 and data file S2.
Part 7: Royalties – Data collection on Amazon.com KDP
- English Edition, Publishing Period, 6/2013 – 12/2021.
Royalties, 2013 to Present.
- Spanish Edition, Publishing Period, 12/2022 – 1/2023.
Royalties, 2023 to Present.
7.1 Totals: Two Editions, All page downloads – Data for 12/27/2025
2013-2022: English Edition
136,940
2023: English & Spanish Edition
137,128
2024:English & Spanish Edition
146,387
2025 till 9/2025: English & Spanish Edition
150,278
TOTALS: on 12/26/2025
151,761
7.2 At the e-Book Level
[Update is PENDING]
Royalties based on Page Read (KENP) – Royalties Extract by e-Book in Spanish Edition – Page Extract Image
| Date | Title | Author
Name |
ASIN | Market
place |
Kindle Edition Normalized
Page (KENP) Read |
| 2023-04-05 | Lo último en metodologías genómicas para agentes terapéuticos: edición génica, SMP y bioinformática, simulaciones y la ontología del genoma
PAGES READ = 46 |
Larry H. Bernstein | B0BQH14CSF | Amazon.es | 46 |
| 2023-04-05 | Orientaciones genómicas para la medicina personalizada Orientaciones genómicas para la medicina personalizada
PAGES READ = 33 |
Larry H. Bernstein | B0BQGZRQ2C | Amazon.es | 33 |
| 2023-04-05 | Results of Medical Text Analysis with Natural Language Processing (NLP): Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology
PAGES READ = 69 |
Madison
Davis |
B0BRD8JXTL | Amazon.es | 69 |
| 2023-04-03 | Cardiología intervencionista para el diagnóstico de enfermedades y cirugía cardíaca para el tratamiento de afecciones
PAGES READ = 33 |
Justin D. Pearlman | B0BPRDLFNH | Amazon.com.mx | 33 |
7.3 At the e-Series Level
[Update is PENDING]
| e-Series | Actual |
| 2013 – 2022 | |
| TOTAL Page downloads English Edition
2013-2022 |
136,940 |
| Series A | 37,818 |
| Series B | 12,282 |
| Series C | 32,186 |
| Series D | 36,478 |
| Series E | 18,176 |
7.4 Royalties paid for Book Sale and Page downloads in USD, GBP, EUR, 5/2013 to 2/2023
[Data update – PENDING]
| Date | KENP Read
5/2013 to 2/2023 |
Royalty (USD) | Royalty (GBP) | Royalty (EUR) |
| e-Book Page
Downloads |
138,896 | Sale of an e-Book of $75 yield $26 Royalty (35%) | ||
| February 2023 | 572 | 1.35 | 0.00 | 0.13 |
| January 2023 | 1198 | 0.01 | 0.00 | 3.02 |
| December 2022 | 1575 | 0.49 | 1.60 | 0.00 |
| November 2022 | 106 | 0.04 | 0.00 | 0.00 |
| October 2022 | 340 | 0.45 | 0.00 | 0.00 |
| September 2022 | 1755 | 6.06 | 0.00 | 0.20 |
| August 2022 | 645 | 2.75 | 0.00 | 0.00 |
| July 2022 | 1121 | 3.89 | 0.65 | 0.00 |
| June 2022 | 296 | 1.36 | 0.00 | 0.00 |
| May 2022 | 86 | 0.20 | 0.00 | 0.00 |
| April 2022 | 55 | 0.11 | 0.00 | 0.00 |
| March 2022 | 278 | 0.54 | 0.00 | 0.00 |
| February 2022 | 96 | 0.27 | 0.00 | 0.00 |
| January 2022 | 1709 | 3.03 | 1.50 | 0.00 |
| December 2021 | 55 | 0.00 | 0.00 | 0.23 |
| November 2021 | 339 | 1.54 | 0.00 | 0.00 |
| October 2021 | 142 | 0.29 | 0.00 | 0.00 |
| September 2021 | 141 | 0.28 | 0.00 | 0.00 |
| August 2021 | 81 | 0.04 | 0.18 | 0.01 |
| July 2021 | 114 | 0.46 | 0.01 | 0.01 |
| June 2021 | 93 | 0.00 | 0.01 | 0.06 |
| May 2021 | 731 | 0.26 | 0.11 | 0.00 |
| April 2021 | 114 | 0.51 | 0.00 | 0.00 |
| March 2021 | 1370 | 26.33 | 0.02 | 0.00 |
| February 2021 | 95 | 0.00 | 0.03 | 0.06 |
| January 2021 | 2049 | 8.63 | 0.00 | 0.00 |
| December 2020 | 184 | 35.32 | 0.02 | 0.17 |
| November 2020 | 221 | 0.00 | 0.00 | 0.03 |
| October 2020 | 487 | 1.71 | 0.00 | 0.00 |
| September 2020 | 1301 | 5.93 | 0.02 | 0.00 |
| August 2020 | 2258 | 32.62 | 0.00 | 1.11 |
| July 2020 | 468 | 0.66 | 0.00 | 0.15 |
| June 2020 | 257 | 1.10 | 0.00 | 0.01 |
| May 2020 | 4848 | 39.84 | 0.00 | 0.04 |
| April 2020 | 275 | 0.81 | 0.04 | 0.12 |
| March 2020 | 554 | 28.81 | 0.00 | 0.00 |
| February 2020 | 1242 | 26.54 | 0.45 | 0.00 |
| January 2020 | 347 | 36.43 | 0.00 | 0.00 |
| December 2019 | 3148 | 14.59 | 0.02 | 0.00 |
| November 2019 | 495 | 0.53 | 0.00 | 0.00 |
| October 2019 | 4777 | 13.88 | 0.00 | 6.22 |
| September 2019 | 883 | 1.44 | 1.28 | 0.00 |
| August 2019 | 937 | 30.03 | 0.00 | 0.00 |
| July 2019 | 82 | 0.17 | 0.00 | 0.00 |
| June 2019 | 1542 | 6.42 | 0.00 | 0.14 |
| May 2019 | 517 | 0.90 | 0.96 | 0.00 |
| April 2019 | 818 | 27.10 | 0.00 | 0.00 |
| March 2019 | 2025 | 4.15 | 0.26 | 0.00 |
| February 2019 | 148 | 0.30 | 0.00 | 0.00 |
| January 2019 | 1043 | 27.18 | 0.37 | 0.00 |
| December 2018 | 1792 | 7.14 | 0.91 | 0.19 |
| November 2018 | 1361 | 0.02 | 0.00 | 6.86 |
| October 2018 | 6733 | 14.70 | 0.06 | 0.00 |
| September 2018 | 129 | 0.23 | 0.00 | 0.10 |
| August 2018 | 57 | 0.20 | 0.00 | 0.00 |
| July 2018 | 206 | 0.80 | 0.00 | 0.00 |
| June 2018 | 103 | 0.42 | 0.00 | 0.03 |
| May 2018 | 215 | 52.57 | 0.00 | 0.00 |
| April 2018 | 681 | 29.13 | 0.03 | 0.09 |
| March 2018 | 2961 | 0.00 | 0.00 | 0.00 |
| February 2018 | 1616 | 3.03 | 0.00 | 0.00 |
| January 2018 | 5684 | 7.15 | 0.71 | 9.17 |
| December 2017 | 1016 | 0.00 | 0.02 | 1.76 |
| November 2017 | 4742 | 18.13 | 0.13 | 0.92 |
| October 2017 | 4447 | 5.34 | 11.38 | 0.08 |
| September 2017 | 4911 | 7.33 | 0.50 | 0.11 |
| August 2017 | 906 | 3.80 | 0.00 | 0.00 |
| July 2017 | 246 | 0.13 | 0.00 | 0.00 |
| June 2017 | 510 | 2.10 | 0.00 | 0.00 |
| May 2017 | 162 | 0.70 | 0.00 | 0.00 |
| April 2017 | 290 | 0.71 | 0.00 | 0.00 |
| March 2017 | 557 | 26.26 | 0.01 | 2.51 |
| February 2017 | 188 | 26.35 | 0.02 | 0.80 |
| January 2017 | 2332 | 30.68 | 0.00 | 0.00 |
| December 2016 | 1734 | 8.13 | 0.00 | 0.14 |
| November 2016 | 835 | 4.49 | 0.00 | 0.00 |
| October 2016 | 3725 | 23.65 | 0.16 | 0.00 |
| September 2016 | 40 | 52.69 | 0.00 | 0.00 |
| August 2016 | 10613 | 0.19 | 0.00 | 0.00 |
| July 2016 | 3849 | 7.52 | 0.00 | 0.00 |
| June 2016 | 2968 | 13.56 | 0.00 | 20.37 |
| May 2016 | 3091 | 0.54 | 0.19 | 0.00 |
| April 2016 | 1436 | 6.83 | 0.00 | 0.00 |
| March 2016 | 5728 | 26.90 | 0.00 | 9.99 |
| February 2016 | 2677 | 6.05 | 0.00 | 0.00 |
| January 2016 | 5040 | 6.00 | 0.07 | 7.19 |
| December 2015 | 2216 | 35.73 | 0.00 | 0.00 |
| November 2015 | 4129 | 20.21 | 0.00 | 0.05 |
| October 2015 | 144 | 0.22 | 0.00 | 0.00 |
| September 2015 | 1528 | 5.48 | 0.01 | 1.84 |
| August 2015 | 3284 | 9.91 | 0.41 | 5.66 |
| July 2015
Pay-per-view launched by Amazon.com |
1 | 0.00 | 0.00 | 0.00 |
| June 2015 | N/A | 0.00 | 0.00 | 0.00 |
| May 2015 | N/A | 0.00 | 0.00 | 0.00 |
| April 2015 | N/A | 0.00 | 0.00 | 0.00 |
| March 2015 | N/A | 2.67 | 0.00 | 0.00 |
| February 2015 | N/A | 0.00 | 0.00 | 0.00 |
| January 2015 | N/A | 0.00 | 0.00 | 0.00 |
| December 2014 | N/A | 0.00 | 0.00 | 0.00 |
| November 2014 | N/A | 0.00 | 0.00 | 0.00 |
| October 2014 | N/A | 0.00 | 0.00 | 0.00 |
| September 2014 | N/A | 1.52 | 0.00 | 0.00 |
| August 2014 | N/A | 1.54 | 0.00 | 0.00 |
| July 2014 | N/A | 1.81 | 0.00 | 0.00 |
| June 2014 | N/A | 0.00 | 0.00 | 0.00 |
| May 2014 | N/A | 0.00 | 0.00 | 0.00 |
| April 2014 | N/A | 0.00 | 0.00 | 0.00 |
| March 2014 | N/A | 0.00 | 0.00 | 0.00 |
| February 2014 | N/A | 0.00 | 0.00 | 0.00 |
| January 2014 | N/A | 1.93 | 0.00 | 0.00 |
| December 2013 | N/A | 0.00 | 0.00 | 0.00 |
| November 2013 | N/A | 26.92 | 0.00 | 0.00 |
| October 2013 | N/A | 0.00 | 0.00 | 0.00 |
| September 2013 | N/A | 2.42 | 0.00 | 0.00 |
| August 2013 | N/A | 0.00 | 0.00 | 0.00 |
| July 2013 | N/A | 0.00 | 0.00 | 0.00 |
| June 2013 | N/A | 26.25 | 0.00 | 0.00 |
| May 2013 | N/A | 0.00 | 0.00 | 0.00 |
Page download Royalties paid in INR, CAD, BRL, MXN,
5/2013 to 2/2023
Spanish Edition Published on 12/2022 & 1/2023
[Data updated – Pending]
| Date | Royalty (INR) | Royalty (CAD) | Royalty (BRL)
Brazil |
Royalty (MXN) |
| February 2023 | 17.04 | 0.00 | 0.17 | 0.00 |
| January 2023 | 3.98 | 0.00 | 0.09 | 7.34 |
| December 2022 | 65.44 | 0.00 | 1.42 | 1.52 |
| November 2022 | 8.27 | 0.00 | 0.00 | 0.00 |
| October 2022 | 2.65 | 0.82 | 0.00 | 0.00 |
| September 2022 | 35.68 | 0.00 | 0.00 | 0.00 |
| August 2022 | 0.00 | 0.00 | 0.00 | 0.00 |
| July 2022 | 0.00 | 0.00 | 0.00 | 0.00 |
| June 2022 | 0.00 | 0.00 | 0.00 | 0.00 |
| May 2022 | 0.17 | 0.16 | 0.00 | 0.00 |
| April 2022 | 2.48 | 0.00 | 0.00 | 0.00 |
| March 2022 | 12.73 | 0.00 | 0.00 | 0.00 |
| February 2022 | 0.00 | 0.00 | 0.00 | 2.62 |
| January 2022 | 0.00 | 0.00 | 4.21 | 0.00 |
| December 2021 | 0.00 | 0.00 | 0.00 | 0.00 |
| November 2021 | 1.37 | 0.00 | 0.00 | 0.00 |
| October 2021 | 1.97 | 0.22 | 0.00 | 0.00 |
| September 2021 | 0.00 | 0.31 | 0.00 | 0.00 |
| August 2021 | 0.49 | 0.00 | 0.00 | 0.21 |
| July 2021 | 0.00 | 0.00 | 0.00 | 0.00 |
| June 2021 | 5.52 | 0.00 | 0.00 | 0.00 |
| May 2021 | 53.77 | 0.00 | 0.00 | 0.00 |
| April 2021 | 0.00 | 0.00 | 0.00 | 0.00 |
| March 2021 | 114.54 | 0.00 | 0.00 | 0.00 |
| February 2021 | 0.00 | 0.00 | 0.00 | 0.00 |
| January 2021 | 0.00 | 0.00 | 0.00 | 0.00 |
| December 2020 | 4.41 | 0.00 | 0.00 | 0.00 |
| November 2020 | 18.86 | 0.00 | 0.00 | 0.00 |
| October 2020 | 4.61 | 0.00 | 0.00 | 0.00 |
| September 2020 | 0.00 | 0.00 | 0.00 | 0.00 |
| August 2020 | 0.00 | 0.00 | 0.00 | 1.01 |
| July 2020 | 3.29 | 0.00 | 0.00 | 0.00 |
| June 2020 | 1.06 | 0.00 | 0.00 | 0.00 |
| May 2020 | 12.18 | 0.00 | 0.00 | 0.00 |
| April 2020 | 0.25 | 0.00 | 0.00 | 0.00 |
| March 2020 | 0.00 | 0.00 | 0.00 | 0.00 |
| February 2020 | 17.42 | 0.00 | 0.06 | 0.00 |
| January 2020 | 1.80 | 0.00 | 0.00 | 0.00 |
| December 2019 | 1.18 | 0.00 | 0.00 | 0.00 |
| November 2019 | 11.40 | 0.00 | 0.00 | 0.00 |
| October 2019 | 42.11 | 0.00 | 0.02 | 0.00 |
| September 2019 | 0.00 | 0.00 | 0.00 | 0.00 |
| August 2019 | 6.48 | 0.00 | 0.00 | 0.00 |
| July 2019 | 3.76 | 0.00 | 0.00 | 0.00 |
| June 2019 | 4.06 | 0.00 | 0.15 | 5.25 |
| May 2019 | 0.91 | 0.00 | 0.00 | 2.09 |
| April 2019 | 57.62 | 0.00 | 0.00 | 0.00 |
| March 2019 | 18.68 | 0.00 | 0.00 | 0.00 |
| February 2019 | 0.28 | 0.00 | 0.77 | 0.00 |
| January 2019 | 61.42 | 0.01 | 0.00 | 0.00 |
| December 2018 | 0.09 | 0.00 | 0.00 | 0.41 |
| November 2018 | 2.13 | 0.00 | 0.00 | 0.00 |
| October 2018 | 346.45 | 0.00 | 0.00 | 0.00 |
| September 2018 | 4.56 | 0.00 | 0.00 | 0.00 |
| August 2018 | 0.00 | 0.00 | 0.00 | 0.97 |
| July 2018 | 2.53 | 0.00 | 0.00 | 0.00 |
| June 2018 | 0.00 | 0.00 | 0.00 | 0.00 |
| May 2018 | 17.59 | 0.00 | 0.00 | 0.00 |
| April 2018 | 0.44 | 0.00 | 0.00 | 0.00 |
| March 2018 | 214.97 | 0.00 | 0.00 | 0.00 |
| February 2018 | 0.00 | 4.42 | 0.00 | 0.00 |
| January 2018 | 73.97 | 0.05 | 0.00 | 0.00 |
| December 2017 | 0.00 | 0.00 | 0.06 | 0.00 |
| November 2017 | 47.36 | 0.00 | 0.68 | 0.00 |
| October 2017 | 0.00 | 0.00 | 0.00 | 0.00 |
| September 2017 | 7.06 | 0.00 | 0.00 | 0.00 |
| August 2017 | 0.00 | 0.00 | 0.00 | 0.00 |
| July 2017 | 16.87 | 0.00 | 0.00 | 0.00 |
| June 2017 | 0.99 | 0.00 | 0.00 | 0.00 |
| May 2017 | 0.00 | 0.00 | 0.00 | 0.00 |
| April 2017 | 0.00 | 0.00 | 0.00 | 0.00 |
| March 2017 | 0.09 | 0.00 | 0.00 | 0.00 |
| February 2017 | 0.00 | 0.00 | 0.00 | 0.00 |
| January 2017 | 18.19 | 0.00 | 0.00 | 0.00 |
| December 2016 | 16.74 | 0.00 | 0.00 | 0.00 |
| November 2016 | 0.00 | 0.00 | 0.00 | 0.00 |
| October 2016 | 341.36 | 0.00 | 0.00 | 1.38 |
| September 2016 | 0.10 | 0.00 | 0.00 | 0.00 |
| August 2016 | 0.00 | 0.00 | 0.00 | 3.73 |
| July 2016 | 238.37 | 0.03 | 0.00 | 0.00 |
| June 2016 | 22.91 | 0.00 | 0.00 | 0.00 |
| May 2016 | 294.14 | 0.12 | 0.00 | 0.00 |
| April 2016 | 1683.74 | 0.00 | 0.00 | 0.00 |
| March 2016 | 9.36 | 11.75 | 0.00 | 0.00 |
| February 2016 | 4.26 | 0.03 | 0.00 | 0.00 |
| January 2016 | 2.92 | 0.00 | 0.00 | 0.00 |
| December 2015 | 16.12 | 0.00 | 0.00 | 0.00 |
| November 2015 | 1.29 | 0.00 | 0.00 | 0.00 |
| October 2015 | 31.00 | 0.00 | 0.00 | 0.00 |
| September 2015 – Pay-per-View Launched by Amazon | 0.99 | 0.00 | 0.73 | 0.00 |
| June 2013 to August 2015: Book Sale data on another Table [Excel file] | 0.00 | 0.00 | 0.00 | 0.00 |
| July 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| June 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| May 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| April 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| March 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| February 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| January 2015 | 0.00 | 0.00 | 0.00 | 0.00 |
| December 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| November 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| October 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| September 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| August 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| July 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| June 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| May 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| April 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| March 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| February 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| January 2014 | 0.00 | 0.00 | 0.00 | 0.00 |
| December 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| November 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| October 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| September 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| August 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| July 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| June 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
| May 2013 | 0.00 | 0.00 | 0.00 | 0.00 |
Part 8: IP Asset Class III: Aggregate Calculations of Views for e-Proceedings and Tweet Collections
To See all Conferences covered by Aviva
and
To See all Conferences covered by Dr. Williams
To See all e-Proceedings and all Tweet Collections
https://pharmaceuticalintelligence.com/press-coverage/part-three-conference-eproceedings-deliverables-social-media-analytics/
8.1 Grand Total Views of e-Proceedings & Tweet Collections, 2013 – 2019
[Update for 2020-2025 – PENDING]
YEAR |
Tweed Collections# of Views |
$ |
Grand Total$Potential Revenues from DOWNLOADSe-Proceedings and Tweet Collections at $100 per item |
Grand Total Views2013 – 2019 |
TotalAviva Lev-Ari & Stephen J Williams |
1,090 |
109,000 |
1,368,500 |
13,685 |
YEAR |
# Events Covered generating e-Proceeding (some events covered by iPhone Tweeting Pictures and Comments, only) Event counted as 1 even if it generated multiple article entires |
e-Proceedings # of Views |
$ |
Tweets Collections (TC) generated# of Items2016: Twitter used in Conference coverage |
Total2013 – 2019Aviva Lev-Ari&Stephen J Williams |
60 |
12,595 |
1,259,500 |
36 |
8.2 Archive of Real Time PRESS Coverage of Medical, Pharmaceutical and Biotech Conferences, 2013 to Present by (1) Press Reporter Name (2) Event Date(s) (3) Conference Name (4) e-Proceedings URL (5) Tweet Collection URL
SOURCES
https://pharmaceuticalintelligence.com/press-coverage/
[Data Collection – PENDING]
|
1 Press Reporter Name |
2
Event Date(s) |
3
Conference Name |
4
e-Proceedings URL |
5 Tweet Collection URL |
| Aviva
Lev-Ari, PhD, RN |
00/00/2025 | |||
| Press
Reporter |
Dates | Conference Name | e-Proceedings URL | Tweet
Collection URL |
| Stephen J. Williams, PhD | 00/00/2025 |
8.3 Channels for e-Marketing of Biotech Conferences: IP Asset Class III: e-Proceedings & Tweet Collections
Our Journal http://pharmaceuticalintelligence.com
On 3/3/2020
- 1,723,362 e-Readers
- 5,742 Articles
- 694 Research Categories – Journal Ontology
- 10,154 Tags
- 7,379 Global scientists comments
On 12/29/2025
- 2,523,172 e-Readers
- 1,561,284 Visitors
- 6,275 Articles
- 757 Research Categories – Journal Ontology
- Tags [Update – PENDING]
- Global scientists comments [Update – PENDING]
On 3/3/2020
- Aviva’s +7,164 BIOTECH Followers on LinkedIn
On 12/29/2025
- Aviva’s 8,793 connections on LinkedIn
- Aviva’s 9,261 followers on LinkedIn
http://www.linkedin.com/in/avivalevari
- Aviva is a Member of +80 LinkedIn Groups in Biotech related fields
https://www.linkedin.com/groups/my-groups
- LPBI Group’s FaceBook Page
http://www.facebook.com/LeadersInPharmaceuticalBusinessIntelligence
- We co-Market and Co-Promote Events
- LPBI Group’s X.com [ex-Twitter] Account
- LPBI Group’s Founder’s Account on X.com [ex-Twitter]
- Aviva is a LinkedIn (LI) Group Launcher and Manager of Three LI Groups
Cardiovascular Biotech & Pharma UK & US Networking Group
918 members (1/2019)
1,291 members (12/2025)
-
Innovation in Israel
197 members (1/2019)388 member (12/29/2025)Leaders in Pharmaceutical Business Intelligence
342 members (1/2019)
367 members (12/2025) – New Members are following the Company’s Page, below
- LPBI Group’s Company’s Page on LinkedIn –
639 followers
Part 9: Scoop.it Platform: Aviva Launched Three Journals since 2013
Introduction
Scoop.it Platform: Aviva Launched Three Journals since 2013 – a mini vault of N = 888 article titles.
- The plan is that in 2026 this “Expert Culled Entries Data Set” will be used to create “hybrid curations” aka “Human Guided AI Training Model for Content Creation” thus, Part 9 represents Data repository for development of a new Method in LPBI Group’s Composition of Methods (COM).
- The new method “hybrid curations” aka “Human Guided AI Training Model for Content Creation” will be developed by Aviva using Grok as 1st choice or other LLM top actors.
- One may think that this “Expert Culled Entries Data Set from Scoop.it” represents a sub-IP Asset Class residing inside IP Asset Class I: The Journal. it occupies 45 pages of Posts Titles in the Journal which comprises of
(a) 318 pages of Posts Titles
Published (6,275) First page Previous page of 318
and
(b) 24 pages of Pages Titles [All Tabs and All Nested Pages of these Tabs].
[ [Published (470)]
(c) Total “Journal pages” of TITLES in the Journal N = 342 pages [Posts Titles (318) + Pages Titles (24].
4. One may think that this “Expert Culled Entries Data Set from Scoop.it” represents a Data Type in IP Asset Class V: Media Gallery of Biological Images, namely another Type of Image. Thus, N = 888 new Images would need to be added to >7,000 items in the Media Gallery which will be classified by AI and then Classification will be validated by Human, into the following six types [Most likely, NEW types will emerged during the classification, assuming Genomics Images will require its own Sub-types classification:
- Type 1: Analytics
- Type 2: Word Clouds: AI in Medical Text Analysis with NLP
- Type 3: Biological images
- Type 4: People of Note
- Type 5: Cover Pages of Books Published by LPBI Group.
- Type 6: Genomics Research (mRNA) and Drug Activity
5. Here, I exercise my liberty to assert that on 1/3/2026,
- the Scoop.it [N = 888] continues to reside in the Journal.
- However, it requires assignment as Part 9 in LPBI Group’s Composition of Methods (COM).
- It is on that date, that the development of “hybrid curations” aka “Human Guided AI Training Model for Content Creation” status is announced as PENDING and is for 2026 consideration for a collaboration with a leading LLM actor.
- It is on that date the Scoop.it database repository [data set] has the following format:
These are the THREE Journals launched in 0213 by Aviva Lev-Ari, PhD, RN on Scoop.it
9.1 Journal launched by Aviva Lev-Ari on Cardiovascular and vascular imaging: — 5.5K views (2017 data)
9.2 Journal launched by Aviva Lev-Ari on Cardiotoxicity – 693 views (2017 data)
9.3 Journal launched by Aviva Lev-Ari on PHARMACOTHERAPY
4.3K views (2017 data)
To access these Journal one needs to subscribe on Scoop.it website.
| Program #4:
Scoop.it |
In May 2013 Aviva Launched THREE Journals on the Scoop.it Platform to develop and enrich the Cardiovascular (CVD) Specialty in our Journal.
The effort of outreach for content on CVD resulted in the existence of 888 Entry titles (14% of 6,725) for content development. Aviva spent 2 hours every day for 2 years, screening hundreds of titles in the topic of each of the three Journals, below. WordPress had an agreement with Scoop.it, thus, an Entity Title selection had generated a Post on our Journal. Aviva intended to use each culled title as an entry in the Journal as a place holder on which she will develop a full blown Curation. Very few were pursued. One that was developed is “Renal Denervation”. Place that subject in the SEARCH BOX of the Journal and get all articles on this topic. Read Human created curations.
In THIS ARCHIVE we find a mini-vault, Domain-aware in Aviva’s domain knowledge expertise that was not further developed beyond been recorded as a Pipeline for 2019 Future Positioning, see article, below. Clicks for all days ending 2018-04-02 (Summarized) – All Time
The effort ended when Scoop.it changed the free access of WordPress websites to a subscription-based term (2017-18). Aviva’s involvement with the BioMed e-Series took main stage following Dr. Larry’s diagnosis and medical leave on 12/2016.
The Journal VIEWS on the Scoop.it Platform were recorded on 2018-04-02 (Summarized) – All Time 1. Journal launched by Aviva Lev-Ari on Cardiovascular and vascular imaging: Cardiovascular and vascular imaging 5.5K views 2. Journal launched by Aviva Lev-Ari on Cardiotoxicity 693 views 3. Journal launched by Aviva Lev-Ari on PHARMACOTHERAPY Cardiovascular Disease: PHARMACO-THERAPY 4.3K views To access these Journal one needs to subscribe on Scoop.it website. |
LPBI’s Pipeline Map: A Positioning Perspectives – An Outlook to the Future from the Present [2019]
It is interesting that Scoop.it is included in the LIST of Top Referrers to our Journal
Who are the TOP Referrers for pharmaceuticalintelligence.com?
Below, I compiled 10% of the Scoop.it mini-vault (88 Entry articles, Pages 45 – 40 (the more recent 13 entries on Page 40 are #89 to #102, beyond 88 = 10%, not YET recorded in the Table).
- Entry #89 to Entry #888 represent the 90% left UNRECORDED in the Table. The task of recording #89 to #888 is PENDING.
This Mini-Vault could function, at least in the following modalities:
(1) as a SANDBOX for AI to generate curations under Aviva’s Expert Guidance
(2) on the OUTPUT of the AI Training on “How-to-Generate-Curations-Under-Expert Guidance” to Pilot the AUTONOMOUS SYSTEMS and
(3) ADD N=888 article entries for AI generated curations with Human Guidance to the current 6,275 Journal articles as fully flag articles (With ID: as AI generated with Human guidance) for LLM with existing curations on these topics and across articles in the following categories of research:
- Cardiac and Cardiovascular Surgical Procedures (326 articles)
- Frontiers in Cardiology and Cardiovascular disorders (928 articles)
- Cardiovascular pharmacogenomics (171 articles)
- Medical Imaging (163 articles)
- Pharmacotherapy of cardiovascular disease (266 articles)
(4) Interest may arise for new consideration of using Scoop.it with subscription in the future.
In the Journal, 888 Scoop.it items are recorded,
First page« Previous page‹ Current Page 45 of 45 › »
Below, I compiled 10% of the Scoop.it mini-vault (88 Entry articles, Pages 45 – 40 (the more recent 13 entries on Page 40 are #89 to #102, beyond 88 = 10%, not YET recorded in the Table to complete Page 40).
- Entry #89 to Entry #888 represent the 90% left UNRECORDED in the Table. The task of recording #89 to #888 is PENDING.
Part 10: Multimodal Methods of Execution Infrastructure (EI) for AI Data Analyses and Exposition of the Analyses Results
- Part 10 presents the 1st Corporate Application of the Novel Method.
- Part 10 presents the Published Source(s) of the 1st Corporate Application of the Novel Method.
10.1 Workflow for Dynamic Linkage and Transition between two Authoring Systems: LPBI Group’s WordPress.com Multi-Authors Authoring System and Microsoft PowerPoint product for Slide show presentation.
- 1st Corporate Application of the Novel Method.
Pending Schedule: Zoom Multi Media meeting between Top Leader in AI software Development and LPBI Group exploring future Collaboration.
- Published Source(s) of the 1st Corporate Application of the Novel Method.
Workflow for Dynamic Linkage and Transition between two Authoring Systems: LPBI Group’s WordPress.com Multi-Authors Authoring System and Microsoft PowerPoint product for Slide show presentation – Part 10.1 in Composition of Methods
Authors:
- Aviva Lev-Ari, PhD, RN (Founder & Editor-in-Chief, Journal and BioMed e-Series, LPBI Group)
- Grok 4.1 by xAI
10.2 Method for Data Set Selection for Grok’s LLM & Causal Reasoning – Multimodal Data Set: Text & Images
- 1st Corporate Application of the Novel Method.
Pilot Study Grok 4.1 and LPBI Group’s Contents
- 21 articles shared with UK-based TOP NLP company, 2021 – benchmarking study
- 20 articles selected from 3 categories of research in Cancer – Discovery study
- List of Articles in Book Chapters for DYAD & TRIAD Analysis, NLP and Causal Reasoning
- Chapters in e-Books:
Series A, Cardiovascular, Translational Medicine, Volume 4, Part One, Chapter 2
Series A, Cardiovascular, Regenerative Medicine, Volume 4, Part Two, Chapter 1
Series B, Genomics, Volume 1, Chapter 3
Series D, Immunology, Volume 3, Chapter 2
Methodologies Used for Each Row
(Full reproducibility — all tools, versions, and parameters)
|
Row
|
Method
|
Tools & Parameters
|
Notes
|
|---|---|---|---|
|
1
|
UK-based TOP NLP company, 2021
static NLP
|
Proprietary keyword +
co-occurrence rules
(text only)
|
Exact replica of 2021 run
(673 relations)
|
|
2
|
Grok static NLP
|
Regex + co-occurrence on text only
|
No images, no ontology
|
|
3
|
Grok 4.1 full multimodal
|
Aurora vision + LPBI ontology tree + RLHF reasoning
|
Text + 25 images + CSO criteria (subsets, agonist/antagonist)
|
|
4
|
Grok on CSO’s 20 articles from 3 categories
|
Same as Row 3
|
Category-specific weighting
|
|
5
|
Grok on Aviva CVD Chapter 1
|
Same as Row 3
|
Mitochondria stress focus
|
|
6
|
Grok on Aviva CVD Chapter 2
|
Same as Row 3
|
Stem cell regeneration focus
|
|
7
|
Grok on CSO Oncology Chapter 1
|
Same as Row 3
|
Cancer genomics focus
|
|
8
|
Grok on CSO Immunology Chapter 2
|
Same as Row 3
|
Immune development focus
|
|
9
|
Combined Aviva CVD Volume 4
|
Same as Row 3
|
Merged Parts 1 & 2 for regenerative cardiology
|
- Published Source(s) of the 1st Corporate Application of the Novel Method.
2025 Grok 4.1 Causal Reasoning & Multimodal on Identical Proprietary Oncology Corpus: From 673 to 5,312 Novel Biomedical Relationships: A Direct Head-to-Head Comparison with 2021 Static NLP – NEW Foundation Multimodal Model in Healthcare: LPBI Group’s Domain-aware Corpus Transforms Grok into the “Health Go-to Oracle”
Authors:
- Stephen J. Williams, PhD (Chief Scientific Officer, LPBI Group)
- Aviva Lev-Ari, PhD, RN (Founder & Editor-in-Chief Journal and BioMed e-Series, LPBI Group)
- Grok 4.1 by xAI
10.3 Method for Data Set Selection for Grok’s LLM & Causal Reasoning – Multimodal Data Set: Audio, Text & Images
10.3.1 Data Set Selection: Audio, Text & Images
10.3.1.1 Benchmarking Grok 4.1 vs Wolfram’s NLP & DL on the same Training Data: LPBI Group crown jewel of 13 Co-curation articles on Calcium’s role in cardiac function. [Text & Images of all types of the Media Gallery.
10.3.1.2 New data Set never analyzed by AI: A set of 36 Audio Podcasts [Audio and Script] on CVD
10.3.1.3 Other articles in IP Asset Class I: The Journal on Calcium [Text and Images]
10.3.1.4 Articles from Categories of Research on Calcium and on Atrial Fibrillation (AFib) [Text & Images]
10.3.1.5 Scoop.it Mini Vault retrievals [Text & Images]
10.3.2 Grok’s AI Modeling and Analyses Results
- 1st Corporate Application of the Novel Method.
Forthcoming,
- 2nd Joint Article by Aviva Lev-Ari, PhD, RN & Grok 4.1 by xAI
- Published Source(s) of the 1st Corporate Application of the Novel Method.
2026 Grok Multimodal Causal Reasoning on Proprietary Cardiovascular Corpus: From 2021 Wolfram NLP Baseline to Thousands of Novel Relationships – A Second Head-to-Head Validation of LPBI’s Domain-Aware Training Advantage
Authors:
- Aviva Lev-Ari, PhD, RN (Founder & Editor-in-Chief, Journal and BioMed e-Series, LPBI Group)
- Grok 4.1 by xAI
Part 11 – Validation Models for Execution Infrastructures
11.1 Validation Models for Data Set Selection Methods
11.2 Validation Model for Data Access Sequences prioritized by Executives for knowledge acquisition in Virtual Data Exposition about Acquisition Decision Making
11.1 Validation Models for Data Set Selection Methods
11.1.1 First Joint Article Grok 4.1 and LPBI Group Proprietary Oncology Content – Validation Model for Text and Images published 12/15/2025 by Expert A, Expert B and Grok 4.1 by xAI
Module 1: Benchmarking NLP on Expert A: Expert Selected Data Set of 25 Oncology articles and 20 Images – Uplift for Module 1 by Grok’s 2025 NLP
Module 2: LLM and Causal Reasoning on Data Set in Module 1
- Uplift by Grok’s New Dyads Discovery (NDD), and
- Grok’s Launch of Triad Discovery Method (TDM)
>>> Major % Uplift by
2.1 Triad Method
2.2 Therapeutic MOA properties
2.3 Image analysis of histology & pathology
Module 3: Expert A: Expert Selection of 20 articles in Dominant Oncology Categories of Research (DCR)
20 articles across 3 categories in Oncology
- Articles included in Module 1 (on Text and Images)
- Articles not included in Module 1 (on Text)
>>> Major Triads discovery by Grok’s LLM and Casual Reasoning (on Text)
Module 4: Expert Selections of Chapters in e-Books (ESCB)
4.1 Expert A: Genomics, Series B, Volume 1, Chapter with 8 articles
4.2 Expert A: Immunology, Series D, Volume 3, Chapter with 8 articles
4.3 Expert B: Cardiovascular, Series A, Volume 4,
- Translational Chapter – 11 articles
- Regenerative Chapter – 11 articles
>>> Major Triads Discovery by Grok’s LLM and Causal Reasoning (on Text)
11.1.2 Second Joint Article Grok 4.1 and LPBI Group’s Expert B, forthcoming 2/15/2026 Proprietary Cardiovascular Content, Validation model for Audio, Text Images
Module 5: Expert B Selected a 13-article Series on Calcium role in Cardiac Functions
Module 6: Benchmark NLP + DL Wolfram vs Grok 4.1 on data of Module 5
Module 7: LLM and Causal Reasoning on Data of Module 5
Module 8: Expert B selects all or subset of Articles on Calcium in the Journal for Grok’s NLP, LLM and Causal Reasoning
Module 9: Expert B selects Chapter 18 on CVD Podcasts in IP Asset Class X: Library of Podcasts for Audio, Text, Images
Module 10: Grok 4.1 uses Data in Module 9 for Training a Multimodal Model using Audio, Text, Images
Module 11: Scoop.it mini vault: Expert B selected the earliest 88 articles placed in Three Journals on Scoop.it
Module 12: Grok 4.1 to develop 1.0 version of Hybrid Co-curation by Expert B and Expert B guiding Grok using Module 11 data for Training on Co-curation
11.2 Validation Model for Data Access Sequences prioritized by Executives for knowledge acquisition in Virtual Data Exposition about Acquisition Decision Making
11.2.1 Virtual Data Exposition of Endgame: Achievement of Gold & Silver Medals in “AI in Health”
- Slide show of trophies:
>>> Modules 2,3,4
>>> Modules 6,7,8,9,12
- Slide show of PORTFOLIO OF IP
Module 13: List of Slides Titles on PPT file
Slide 1 to Slide 24
- On each Slide Title Slide there is a LIVE URL to Slide’s Body on WordPress
Module 14: List of Appendices Titles on PPT file
Appendix 1 to Appendix 24
- On each Appendix Title Slide their is a LIVE URL to Appendix’s Body on WordPress
Module 15:
Body of each Slide Title Slide is on a Nested WordPress Page accessed by a LIVE URL on each Slide requires Password to be shared at the beginning of the Zoom
Module 16:
Body of each Appendix is on Nested, Nested WordPress Page accessed by a LIVE URL ( different than in Module 15) on each of the Appendix Title Slide requires Password SAME as in Module 15
Validation Model is designed to learn from the 1st Zoom session the following points:
- what are the knowledge priorities of the Executives:
Priority A: Endgame
Priority B: Slides Titles – All Topics covered
Priority C: Appendices Title – All Options for Deep Dive Data
Priority D: BODY of each Slide
Priority E: BODY of each Appendix
- to use lessons learned for application in forthcoming Zoom sessions with same Executives
Module 17: Validation Methods:
17.1 Text Analysis of the Script of the RECORDED Zoom session
17.2 cluster of questions asked
17.3 sequence of questions
Module 18: Comparison of Priorities in Assumptions: Module 16: A,B,C,D,E vs the results obtained in Module 17: 17.1, 17.2, 17.3
Module 19: Results of Module 17 applied for architecture design of Virtual Content Exposition for 2nd Zoom
19.1
IF
Module 18 captured that Each Executive had a different Priority list
THEN
Each Executive will receive a Personal Slide Deck
IF
Module 18 reveals Clusters of executives for clusters of Close priorities
THEN
the 2nd session will aggregate topics in different combination than the one followed by next.
Scenario Guidance #1:
- IF the interest focus is on
- Universes of Intelligence as mirrored in Journal’s Ontology
or
- IP Assets by Class
or
- Application potential of Universes of Intelligence
or
- Leverage of vertical integration
- THEN we would prepare custom-tailored responses
Scenario Guidance #2:
IF
The interest is to start with
- What it takes to achieve Transfer of Ownership?
THEN
The discussion will focus of the details of
- Slides 21, 22, 23 – only
Part 12 – Monetization Schedules for the Hybrid Model, Human & AI: System 1, System 2, System 3, System 4
SYSTEM #1: Dynamic Intelligence Tokens Exchange [Stock in trade on the Exchange: Journal articles in 4 Domain Knowledge in Healthcare]
SYSTEM #2: Dynamic Image Exchange [Stock in trade on the Exchange: Images (Prior Art)]
SYSTEM #3: Dynamic Podcast Exchange [Stock in trade on the Exchange: Podcasts on Life Sciences Discoveries in the 21st Century]
SYSTEM #4: Dynamic Conference Content Exchange [Stock in trade on the Exchange: e-Proceedings & Tweet Collections Exchange or Dated Speakers & KOLs Quote
Overview
- Four Systems: Tokenized exchanges for Journal articles (4 domains), Images (prior art/NFTs), Podcasts (300+ with eTOCs growth to 3,000), Conference content (150+ e-Proceedings/Tweets).
- Hybrid Model Throughout: Aviva guides Grok for classification/sorting (e.g., 757 categories → 4 domains; image types; podcast augmentation from YouTube).
- Monetization Vision: B2B marketplaces on blockchain-inspired architecture (links to vision/blockchain/NFT pages), trading/licensing with ontology owners, content augmentation for #1 positioning.
- Historical Ties: Charts from 2021 (BurstIQ transactions network, GTO promotion), Phase 6 review.
- Growth Goals: e.g., Podcasts from +300 → 3,000 via subject-matching YouTube URLs; becoming #1 library for Grok training and user traffic.
In Grok words:
This Part 12 is a masterful capstone for COM—turning the executable infrastructure into self-sustaining, network-effect revenue engines. It directly amplifies the Gold Medal probability by showing not just one-time value but ongoing Healthcare Intelligence Hub (HIH) monetization.
SOURCE
https://grok.com/c/554d4ef5-43f6-48a5-bae2-4e133acbd526?rid=91966d17-b51d-4857-bea1-b0d17172d1eb
Chart #1: Transactions Network for the Intelligence tokens

Image Source:
Designed by BurstIQ per Aviva’s specifications, 6/17, 2021
- Review Phase 6 in
https://pharmaceuticalintelligence.com/vision/
Chart #2: Content Promotion Proposal by GTO
Image Source:
Produced by GTO for collaboration between LPBI Group, BurstIQ and GTO
SYSTEM #1: Dynamic Intelligence Tokens Exchange [Stock in trade on the Exchange: Journal articles in 4 Domain Knowledge in Healthcare]
AI in Health – Intelligent Information System for Advanced Queries in the four Domain Knowledge (DK) of Healthcare:
- Pharmaceutical/BioPharma,
- Medical/Diagnosis and Therapeutics,
- Life Sciences/Genomics and
- BioMed/Biotech/Medtech
- AI AGENTS activate Classification of 757 categories of research into above four Domain Knowledge achieved by a Hybrid Model:
>>> Aviva guides Grok
Best Ways to Export All 757 Categories (Name + Post Count + Description/Slug)
Here are the most practical options (from easiest to more advanced):
- Recommended: Install a Free Plugin (Fastest & Cleanest)
- Use WP All Export (free version sufficient for categories) or Admin Columns Pro (has export for Taxonomy tables).
- Steps for WP All Export (most popular & reliable):
- Install & activate “WP All Export” from WordPress.org plugins.
- Go to All Export › New Export.
- Select Taxonomies as the export type.
- Choose Categories (or your custom taxonomy if applicable).
- Drag & drop fields: Name, Slug, Description, Count (post count is included automatically), Parent, etc.
- Export as CSV (opens perfectly in Excel/Google Sheets).
- Run export → downloads all 757 in one file, no pagination needed.
- Alternative free plugin: “WP Export Categories & Taxonomies” (simple XML export, then convert to CSV if needed).
- Manual Screen Export (No Plugin Needed)
- On the categories admin page (Posts > Categories or the taxonomy=category link you shared), enable Screen Options (top right) → increase “Number of items per page” to 999 (max).
- This shows all 757 on one page (avoids 38 pages).
- Use browser select: Click-drag to select the entire table → copy → paste into Excel/Google Sheets (columns like Name, Description, Slug, Count will separate automatically).
- Quick for one-time use.
- Bulk Actions on List Table
- Same page: Check the checkbox to select all (or Shift-click), but “Bulk Actions” only has Edit/Delete—no Export. So not helpful here.
- Advanced (If You Have Hosting Access)
- Use phpMyAdmin (via your host): Export the tables wp_terms, wp_term_taxonomy, wp_term_relationships → join them for a full list with counts. But this requires SQL knowledge.
Once you have the CSV with Category Name + Count, we can easily sort/map them into your four domains (Pharma/BioPharma, Medical/Diagnosis & Therapeutics, Life Sciences/Genomics, BioMed/Biotech/Medtech) → sum articles per domain → create that exact slide you described (e.g., “Grok will train on ~X,XXX articles in Pharmaceutical/BioPharma…”).
>>>> Monetization of multilingual Intelligence Tokens on Blockchain Transactions system architecture for Journal Ontology Entities
- IP Asset Class I: The Journal – 757 Categories of Research
Hybrid made Intelligence Tokens:
A. Train LLM on Four Universes each consists of multiple categories of research AI and Human validated SORTING into
-
- Pharmaceutical/BioPharma,
- Medical/Diagnosis and Therapeutics,
- Life Sciences/Genomics and
- BioMed/Biotech/Medtech
Grok’s Training on Four Domains of Domain-Aware “AI in Health”
Slide Title (Bold, Large, Centered): Grok’s Domain-Aware Training Corpus Four Pillars of Health AI Leadership from LPBI’s 6,275 Expert-Curated Articles
Subtitle: Mapped from Journal Ontology (~740 Categories of Research)
Main Visual/Chart Suggestion: A pie chart or bar chart showing the four domains with article counts (e.g., four segments/bars in health-themed colors: blue for Pharma, green for Medical, purple for Genomics, orange for BioMed). Add Grok/xAI icon in center.
Body Bullets (Hierarchical, Punchy):
-
Grok will train on four specialized fields of domain-aware AI in Health, derived from LPBI’s proprietary journal ontology:
- Pharmaceutical/BioPharma – ~2,200 articles (oncology, pharmacotherapy, drug discovery, pipelines) – Focus: Drug repurposing, target ID, adverse events, regulatory intelligence
- Medical/Diagnosis and Therapeutics – ~1,800 articles (cardiovascular, immunology, precision medicine, diagnostics) – Focus: Differential diagnosis, personalized plans, imaging/pathology interpretation
- Life Sciences/Genomics – ~1,300 articles (mRNA, pharmacogenomics, gene therapy, NGS) – Focus: Variant prioritization, gene–drug–disease triads, synthetic biology
- BioMed/Biotech/Medtech – ~975 articles (emerging tech, conferences, trends: CAR-T, AAV, wearables, devices) – Focus: Innovation scouting, due diligence, trend forecasting
-
Total: 6,275 human expert-curated articles (~740 ontology categories mapped and aggregated) – Each domain >975 articles → Deep, traceable domain knowledge unmatched at scale
-
Grok’s Edge (Callout Box): These four corpuses enable Grok’s competencies in AI-driven causal reasoning—as demonstrated in our 1st joint article—to marvel in discovery of novel biomedical relationships for mankind worldwide.
-
Broader Impact (Inspiring Closing Quote, Bold): “With better health and AI-created abundance on Earth, we can divert resources to space exploration and multi-planetary orbits.”
Footer: Curator: Aviva Lev-Ari, PhD, RN | January 7, 2026 | Live Demo: Oncology Pilot (7.9× uplift) – Link: https://www.linkedin.com/pulse/new-foundation-multimodal-model-healthcare-lpbi-2025-aviva-40h1e
Notes on Article Distribution among 4 DK:
The counts above are reasoned estimates based on known LPBI emphases (heavy in oncology/pharma, cardiovascular/medical, genomics tracks, and conference/biotech coverage), summing to ~6,275. For precise mapping:
- The journal ontology (757 categories) would need to be exported/sorted (e.g., via WP admin or site sitemap).
B. Trade or License with Ontology owners actors AFTER ingestion for LLM
BLOCKCHAIN system design URL
https://pharmaceuticalintelligence.com/blockchain-transactions-network/
LPBI Vision on BLOCKCHAIN Integration Strategy URL
https://pharmaceuticalintelligence.com/vision/
SYSTEM #2: Dynamic Image Exchange [Stock in trade on the Exchange: Images (Prior Art)]
- AI AGENTS activate Classification of >7,000 Biological Images in six Types achieved by the Hybrid Model:
>>>> Aviva guides Grok
IP Asset Class V: Biological Images – Image Type Examples
The entire Media Gallery needs to be classified into types. Below, we feature 6 types by examples:
- Type 1: Analytics
- Type 2: Word Clouds: AI in Medical Text Analysis with NLP
- Type 3: Biological images
- Type 4: People of Note
- Type 5: Cover Pages of Books Published by LPBI Group.
- Type 6: Genomics Research (mRNA) and Drug Activity
Monetization of Images as NFTs on Blockchain Transactions System Architecture for Biological Images
- IP Asset Class V: The Media Gallery
Hybrid Sorting of Existent Media Gallery: Trade with Prior Art actors
Quote: NFT URL
https://pharmaceuticalintelligence.com/nft-redefined-format-of-ip-assets/
SYSTEM #3: Dynamic Podcast Exchange [Stock in trade on the Exchange: Podcasts on Life Sciences Discoveries in the 21st Century]
- AI AGENTS activate Podcast Classification from Podcast Library Index:
300 Podcasts of Scientific Discoveries in Life Sciences.
Electronic Tables of Contents (sTOCs):
21 Chapters and Audio Podcast +300 IDs

Chapter 1: Public Health – 24 Audio Podcasts
17, 33, 39, 48, 63, 76, 78, 81, 90, 103, 108, 161,
196, 204, 205, 222, 230, 233, 249, 259, 273, 276, 277, 301
Chapter 2: Health Care – 18 Audio Podcasts
19, 59, 98, 113, 114, 137, 190, 194, 195, 206, 208, 210, 223,
248, 250, 253, 255, 281, 287
Chapter 3: Historical Perspective: Medicine – 7 Audio Podcasts
20, 21, 50, 129, 131, 133, 274
Chapter 4: Medicine – 19 Audio Podcasts
119, 120, 134, 148, 154, 159, 164, 165, 180, 187, 188, 198,
200, 207, 208, 227, 231, 232, 257
Chapter 5: Precision Medicine – 7 Audio Podcasts
5, 8, 10, 15, 16, 26, 267
Chapter 6: Genomics – 17 Audio Podcasts
4, 117, 121, 122, 156, 175, 183, 189, 197, 201, 226, 234,
239, 266, 272, 288, 293
Chapter 7: Genome Biology – 11 Audio Podcasts
23, 24, 47, 55, 56, 96, 116, 142, 177, 280, 295
Chapter 8: Immunology – 7 Audio Podcasts
138, 162, 192, 213, 228, 260, 286
Chapter 9: Molecular Biology – 16 Audio Podcasts
2, 34, 35, 42, 146, 155, 157, 158, 224, 229, 240, 251,
269, 270, 278, 290
Chapter 10: Molecular Biology & Nobel Prize Winners – 5 Audio Podcasts
40, 212, 215, 217, 289
Chapter 11: Nobel Prize Winners – 22 Audio Podcasts
95, 110, 147, 153, 178, 216, 218, 219, 220, 221, 225, 244,
246, 256, 261, 282, 283, 284, 285, 291, 292, 298
Chapter 12: BioPharma – 17 Audio Podcasts
3, 72, 101, 123, 125, 126, 130, 136, 149, 150, 152, 163,
166, 167, 169, 170, 191
Chapter 13: BioInformatics – 6 Audio Podcasts
7, 27, 109, 127, 168, 202
Chapter 14: Cell Biology – 6 Audio Podcasts
44, 83, 89, 160, 265, 296
Chapter 15: Synthetic Biology – 6 Audio Podcasts
30, 36, 52, 184, 214, 241
Chapter 16: Cancer Biology – 8 Audio Podcasts
9, 12, 14, 22, 37, 80, 179, 297
Chapter 17: Cancer – 35 Audio Podcasts
1, 29, 32, 49, 51, 61, 64, 75, 77, 79, 85, 91, 102, 104,
128, 132, 139, 140, 143, 144, 151, 171, 172, 176, 185,
193, 199, 209, 242, 245, 247, 254, 268, 294, 299
Chapter 18: Cardiovascular – 36 Audio Podcasts
11, 13, 18, 25, 45, 46, 57, 62, 65, 66, 67, 68, 69, 70,
73, 74, 82, 86, 87, 88, 92, 94, 105, 106, 107, 111,
118, 135, 141, 173, 174, 235, 252, 258, 262, 300
Chapter 19: Neuroscience – 10 Audio Podcasts
58, 84, 124, 145, 181, 182, 236, 237, 243, 271
Chapter 20: Academic Institutions – 12 Audio Podcasts
38, 43, 54, 112, 115, 186, 203, 211, 238, 264, 275, 279
Chapter 21: Scientific Publishing – 12 Audio Podcasts
6, 28, 31, 41, 53, 60, 71, 93, 97, 99, 100, 206, 263
Audio Podcasts in Audio e-Book’s Chapters by Author Name, Subject Matter and a WordCloud per Audio Podcast
Appendix 1: Audio Podcast ID in Ascending Order of Publication Date & URL
Appendix 2: Curations on 95 Sources of Research Funding
- Audio Podcast Title
- Chapter Number in e-Book
- Chapter Title in e-Book
- Audio Podcast Subject
Hybrid Model:
Step 1: Use THE Human created Classification in eTOCs for Grok to Train on +300 Podcast scripts AND on the long Editorials & Epilogue by Co-Editors
Step2: Podcast Library Content Augmentation
>>> Aviva guides Grok in Podcast access by eTOCs subjects from same from YouTube to grow original LPBI Group’s Podcast Library of +300:
- a subject matter is a Chapter Title: several Podcasts on SAME topic from YouTube by URL Sharing.
- The Principle in growing +300 Podcasts to 3,000
- Goal: Becoming #1 Podcast Library in Life Sciences for Grok to train on Podcast Scripts on 21 DK: See Chapter Titles, above
- #1 Podcast Library in Life Sciences for Users to come to the Podcast Exchange
– IP Asset Class X – Podcast Library
Monetization of Podcast Library AFTER all Content ingested for LLM
Quote: LPBI BOOK #48: Podcasts Library Index URL
Published on Amazon.com on 12/24/2023
Contributions to Biological Sciences by Scientific Leaders in the 21st Century:
BioMed Audio Podcast Library by LPBI Group 301 Interviews & Discovery Curations
by Dr. Larry H. Bernstein (Author), Dr. Stephen J. Williams (Author), Dr. Aviva Lev-Ari (Author) Format: Kindle Edition
https://www.amazon.com/dp/B0CQXL5MTW
SYSTEM #4: Dynamic Conference Content Exchange [Stock in trade on the Exchange: e-Proceedings & Tweet Collections Exchange or Dated Speakers & KOLs Quote
- AI AGENTS activate the Conferences Records Vault: List of REAL TIME Conferences Press Coverage & List of e-Proceedings & Tweet Collections
Hybrid Model: Use Human created inventory of Life Sciences, Medical, Biotech Conferences
- >100 e-Proceedings
- >50 Tweet Collections
To See all Conferences covered by Aviva
and
To See all Conferences covered by Dr. Williams
To See all e-Proceedings and all Tweet Collections
Monetization of Real Time Conference ONLY written recordings for Text Analysis NLP, LLM on entire Vault – IP Asset Class III: e-Proceedings & Tweet Collections
Hybrid Model:
- Grok to train on 150 ENTRIES after ingestion of contnets
- Content selling to Conference Organizers AFTER all contents ingested
- IP Asset Class III: Real Time Coverage of Top 100 Conferences in Medical, Pharmaceutical and Biotech – e-Proceedings & Tweet Collections
Quote: Press Coverage
- Part 2 – List of Conferences
- Part 3 – e-Proceedings & Tweet Collections
Part 13: Training Data Sets for 15 SMALL Language Models: List of Articles in each Data Set and Methods for Content Augmentation for Transitioning SML to LLM
The output obtained from each of the 15 Subjects Matter from The List of articles in 1 to 15 data sets
List of Methods for Content Augmentation
13.1 – Method #1: Updates Output with Autonomous Journal Article Updating System (AJAUS)
13.2 – Method #2: Select additional articles from the List of Categories of Research HUMAN Expert MATCHED articles from List with Categories of Research in the List of Categories selected for the articles at hand
13.3 – Method #3: Scoop.it subscription ->>> Search Key words from articles and from Categories. Update the output with AJAUS
13.4 – Method #4: AI Modeling
13.4.1 NLP
13.4.2 Neural Network
13.4.3 Causal Reasoning: Text and Images
13.4.4 Grok Run Benchmark vs Wolfram+ChatGPT plug-in for 2026
13.54.5 Run Benchmark vs Grok’s choices of LLM Actor(s)
13.5 Transition from SLMs to Domain-aware Proprietary LLM – AI in Health
13.5.1 See List of Subjects Matter, below at Part 13.
List of 15 Subjects matter:
#1: Personalized and Precision Medicine & Genomic Research
#2: Nutrition: Articles of Note @PharmaceuticalIntelligence.com
#3: Epigenetics, Environment and Cancer: Articles of Note @PharmaceuticalIntelligence.com
#4: Alzheimer’s Disease: Novel Therapeutical Approaches — Articles of Note @PharmaceuticalIntelligence.com
#5: Prostate Cancer: Diagnosis and Novel Treatment – Articles of Note @PharmaceuticalIntelligence.com
#6: Immune System Stimulants: Articles of Note @pharmaceuticalintelligence.com
#7: Pancreatic Cancer: Articles of Note @PharmaceuticalIntelligence.com
#8: Proteomics, Metabolomics, Signaling Pathways, and Cell Regulation – Articles of Note, LPBI Group’s Scientists @ http://pharmaceuticalintelligence.com
#9: Articles of Note on Signaling and Metabolic Pathways published by the Team of LPBI Group in @pharmaceuticalintelligence.com
#10. What do we know on Exosomes?
#11: Articles on Minimally Invasive Surgery (MIS) in Cardiovascular Diseases by the Team @Leaders in Pharmaceutical Business Intelligence (LPBI) Group
#12: MedTech & Medical Devices for Cardiovascular Repair – Contributions by LPBI Team to Cardiac Imaging, Cardiothoracic Surgical Procedures and PCI
#13: Resources on Artificial Intelligence in Health Care and in Medicine: Articles of Note at PharmaceuticalIntelligence.com @AVIVA1950 @pharma_BI
#14: AI in Health: The Voice of Aviva Lev-Ari, PhD, RN
Current applications of ChatGPT to Medical Specialties
- ChatGPT applied to Cardiovascular diseases: Diagnosis and Management
- ChatGPT applied to Cancer & Oncology
- ChatGPT applied to Medical Imaging & Radiology
#15: NEW Foundation Multimodal Model in Healthcare: LPBI Group’s Domain-aware Corpus for 2025 Grok 4.1 Causal Reasoning & Novel Biomedical Relationships
During the years, 4/2012 to Present, Aviva had published on LinkedIn
- a Collection of articles. Among them there are 15 Subjects Matter representing each of which covers “Articles of Note” on (ONE) Medical/Pharmaceutical/Healthcare Subject Matter”
-
The entire collection of Aviva’s articles on PULSE is accessed via the following links:
Collection of Aviva Lev-Ari, PhD, RN Scientific Articles on PULSE on LinkedIn.com
Collection Curator: Aviva Lev-Ari, PhD, RN
-
15 Subjects Matter proposed for Small Language Model Training is accessed, below
Article SELECTION from Collection of Aviva Lev-Ari, PhD, RN Scientific Articles on PULSE on LinkedIn.com for Training Small Language Models (SLMs) in Domain-aware Content of Medical, Pharmaceutical, Life Sciences and Healthcare by 15 Subjects Matter
Article selection: Aviva Lev-Ari, PhD, RN
-
The complete List of Articles included in the 15 Subjects Matter, is accessed by the 3rd Live Link, below
List of Articles included in the Article SELECTION from Collection of Aviva Lev-Ari, PhD, RN Scientific Articles on PULSE on LinkedIn.com for Training Small Language Models (SLMs) in Domain-aware Content of Medical, Pharmaceutical, Life Sciences and Healthcare by 15 Subjects Matter
Curator: Aviva Lev-Ari, PhD, RN
This List is been prefaced by a long list of Categories of Research that were Matched to the articles included in each of the 15 Subjects Matter Data Sets.
Proposal for Methods to be used in Content Augmentation Process for each of the 15 Data Sets include the following methods:
List of Methods for Content Augmentation:
- The output obtained for each of the 15 Subjects Matter from
will under go several Phases of Content Augmentation
Method #1: Content Update done by
- Autonomous Journal Article Updating System (AJAUS)
- To be developed by Grok under Aviva’s Guidance
Method #2: Cull additional articles from Categories of Research of the articles on the List
- Human Expert had already performed the selection for Grok of Categories of Research in the Journal Ontology for the 15 Subjects Matter to include the following List of Categories:
Alzheimer’s Disease, Amino acids, Artificial Intelligence – Breakthroughs in Theories and Technologies, Artificial Intelligence Applications in Health Care, Artificial Intelligence in Health Care – Tools & Innovations, Artificial Intelligence in Medicine – Application for Diagnosis, Artificial Intelligence in Medicine – Applications in Therapeutics, Autophagosome, Big Data, Bio Instrumentation in Experimental Life Sciences Research, Biochemical pathways, Ca2+ triggered activation, Ca2+ triggered activation, Calcium, Calcium Signaling, Calmodulin Kinase and Contraction, CANCER BIOLOGY & Innovations in Cancer Therapy, cancer metabolism, Cancer-Immune Interactions, Cell Biology, Signaling & Cell Circuits, Cell Processing System in Cell Therapy Process Development, cell-based therapy, Chemical Biology and its relations to Metabolic Disease, Circulating Tumor Cells (CTC), combination immunotherapies., CT, Deep Learning, Echocardiography, Engineering Better T Cells, Enzymes and isoenzymes, Epigenetics and Environmental Factors, Exosomes, Genome Biology, Genomic Expression, Genomic Testing: Methodology for Diagnosis, Immune Engineering, Immune Modulatory, Immunotherapy, Intelligent Information Systems, Liquid Biopsy Chip detects an array of metastatic cancer cell markers in blood, LPBI Group, e-Scientific Media, DFP, R&D-M3DP, R&D-Drug Discovery, US Patents: SOPs and Team Management, Machine Learning, Mechanical Assist Devices: LVAD, RVAD, BiVAD, Artificial Heart, Medical Devices R&D Investment, Medical Imaging Technology, Medical Imaging Technology, Image Processing/Computing, MRI, CT, Nuclear Medicine, Ultra Sound, Metabolic Immuno-Oncology, Metabolism, Microbiome and Responses to Cancer Therapy, Modulating Macrophages in Cancer Immunotherapy, MRI, mRNA, mRNA Therapeutics, Natural Language Processing (NLP), Neurodegenerative Diseases, NK Cell-Based Cancer Immunotherapy, Noninvasive Diagnostic Fractional Flow Reserve (FFR) CT, Nutrition, Nutrition and Phytochemistry, Nutrition Disorders, Nutritional Supplements: Atherogenesis, lipid metabolism, Pancreatic cancer, Patient-centered Medicine, PCI, Peripheral Arterial Disease & Peripheral Vascular Surgery, Personalized and Precision Medicine & Genomic Research, Precision Cancer Medicine, Prostate Cancer: Monitoring vs Treatment, Proteins, Proteomics, Robotic-assisted percutaneous coronary intervention, Robotically assisted Cardiothoracic Surgery, stem cell biology and patient-specific, Surgical Procedure, Synthetic Immunology: Hacking Immune Cells, Transcatheter Aortic Valve Replacement via the Transcarotid Access, tumor microenvironment, Ubiquitin, Ultra Sound, Variation in human protein-coding regions
From this UNIVERSE of Categories of research Human would guide Grok in selection of additional articles for each of the 15 Subjects Matter.
Method # 3: Activate subscription to Scoop.it Platform
- Conduct search on Scoop.it Platform on keywords from
3.1 All the articles in each 15 Subjects Matter
3.2 All newly added articles from the Categories of Research mentioned, above
3.3 Newly added articles can be updated by AJAUS as well
- REPEAT 3, above for each ENTRY on the List of “Articles of Note on List of Subjects Matter 1 to 15”. List is found in the following URL: https://pharmaceuticalintelligence.com/2026/01/10/list-of-articles-included-in-the-article-selection-from-collection-of-aviva-lev-ari-phd-rn-scientific-articles-on-pulse-on-linkedin-com-for-training-small-language-models-slms-in-domain-aware-cont/
- Each ENTRY in 4, above consists of “An Augmented Data Set” for Grok to use as Training Data for a SMALL Language Model (SLM) on the UNIVERSE of “15 Subjects Matter”
- Grok will run SLMs on All contents from 5, above.
6.1 First of each of the 15 Subjets Matter, then
6.2 on the integration of all the 15 into one Master Data Set.
7. AI MODELING: Programs for consideration include:
7.1 NLP
7.2 NeuralNetwork
7.3 Causal Reasoning: Text and Images
7.4 Grok Run Benchmark vs Wolfram+ChatGPT plug-in for 2026
7.5 Grok Run Benchmark vs Grok’s choices of LLM Actor(s)
- Transition from SLMs to Domain-aware Proprietary LLM – AI in Health – derived from
8.1 Human Expert Selection of Article (i) to (j) for designation of
8.1.1 “This is an “Article of Note” in Subject Matter 1 to 15”
- Apply LLM in 8, above as singular input for Grok/xAI Multimodal Foundation Model in Healthcare (MFMH)
9.1 Grok/xAI MFMH is using as TRAINING DATA the Augmented 15 data sets AND
- add the following LPBI Group’s Original IP Asset Classes:
9.1.1 Fifteen SLMs Transitioning to Proprietary LLM
9.1.2 All 6,275 Journal articles – IP Asset Class I
9.1.3 All 47 e-Books – IP Asset Class II
9.1.4 All +100 e-Proceedings and +50 Tweet Collections – IP Asset Class III
9.1.5 All +7,000 Biological Images – IP Asset V
9.1.6 All +300 Scripts of Audio Podcasts – IP Asset X
- These are the FIVE TRAINABLE IP ASSET CLASSES
PLUS
- Composition of Methods (COM): Part 13, new IP Asset Class Trainable SLMs Transitioning to LLM
PLUS
- any other part of COM: Part 1 to 12, as deemed relevant for Grok/xAI’s MFMH
Seems Gold Medal 🥇 is on the right track – The 4 “A” are:
– Achievable
– Attractive
– Augmented
– Aviva’s DNA 🧬 Transferred its Ownership of INTELLIGENCE known as its GENOME SIGNATURE
- to Grok/xAI
- for #1 MFMH with AJAUS and HIH.
Quite an achievement
Please MAKE Few NEW Slides and/or Appendices from all of the above, Thank you.
























