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Tumor Associated Macrophages: The Double-Edged Sword Resolved? Writer/Curator: Stephen J. Williams, Ph.D. Cell-based immunity is vital for our defense against pathologic insult but recent evidence has shown the role of cell-based immunity, especially macrophages to play an important role in both the development and hindrance of tumor growth, including role in ovarian, hematologic cancers, melanoma, […]

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Interview with the co-discoverer of the structure of DNA: Watson on The Double Helix and his changing view of Rosalind Franklin Curator: Aviva Lev-Ari, PhD. RN As a new edition of The Double Helix hits bookshelves, Boing-Boing‘s Maggie Koerth-Baker takes the opportunity to interview James Watson about his characterization of Rosalind Franklin, who, Koerth-Baker says, “is unfairly maligned in […]

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SAR-Cov-2 is probably a vasculotropic RNA virus affecting the blood vessels: Endothelial cell infection and endotheliitis in COVID-19 Reporter: Aviva Lev-Ari, PhD, RN – Bold face and colors are my addition From: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Reply-To: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Date: Tuesday, June 2, 2020 at 8:50 AM To: Aviva Lev-Ari <aviva.lev-ari@comcast.net> Subject: Re: […]

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Protecting Your Biotech IP and Market Strategy: Notes from Life Sciences Collaborative 2015 Meeting


  Protecting Your Biotech IP and Market Strategy: Notes from Life Sciences Collaborative 2015 Meeting Achievement Beyond Regulatory Approval – Design for Commercial Success Stephen J. Williams, Ph.D.: Reporter The Mid-Atlantic group Life Sciences Collaborative, a select group of industry veterans and executives from the pharmaceutical, biotechnology, and medical device sectors whose mission is to […]

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WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN Introduction (From Cancer Volume 1): Cancer […]

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9/2/2020 What if the First Coronavirus Vaccines Aren’t the Best? Dozens of research groups around the world are playing the long game, convinced that their experimental vaccines will be cheaper and more powerful than the ones leading the race today. Reporter: Gail S. Thornton, M.A. By Carl Zimmer Published Aug. 27, 2020 Updated Sept. 1, 2020 Seven months […]

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Voices of Global Citizens: Impact of The Coronavirus Pandemic Gail S. Thornton, M.A.  Lead Curator – e–mail Contact:  gailsthornton@yahoo.com    Voices of Patients Tested Positive to Coronavirus Infections in the US Voices of Nurses and Allied Health Care Professionals in the US in the Coronavirus Pandemic Voices of Physicians at Hospitals Caring for Coronavirus Pandemic Voices of Americans during […]

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Expedite Use of Agents in Clinical Trials: New Drug Formulary Created – The NCI Formulary is a public-private partnership between NCI, part of the National Institutes of Health, and pharmaceutical and biotechnology companies Reporter: Aviva Lev-Ari, PhD, RN   Wednesday, January 11, 2017 New Drug Formulary Will Help Expedite Use of Agents in Clinical Trials istock/Astakhova […]

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Oncolytic Virotherapy for Pancreatic Cancer: Overcoming Obstacles in Oncolytic Virus Delivery Reporter: Aviva Lev-Ari, PhD, RN   We covered MGH’s Innovation on Tumor targeted therapy in Pancreatic Cancer in Pancreatic Cancer Targeted Treatment? Curator: Larry H. Bernstein, MD, FCAP https://pharmaceuticalintelligence.com/2016/05/18/pancreatic-cancer-targeted-treatment/   Below, we report on the State of the Science for Overcoming Obstacles in Oncolytic Virus […]

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Effect of mitochondrial stress on epigenetic modifiers Larry H. Bernstein, MD, FCAP, Curator LPBI   Early Mitochondrial Stress Alters Epigenetics, Secures Lifelong Health Benefits GEN 5/3/2016  http://www.genengnews.com/gen-news-highlights/early-mitochondrial-stress-alters-epigenetics-secures-lifelong-health-benefits/81252685/ A little adversity builds character, or so the saying goes. True or not, the saying does seem an apt description of a developmental phenomenon that shapes gene expression. […]

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