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Diagnostic and Interventional Cardiology (DAIC): 2020 Top 25 Best Performing Articles

Posted in Frontiers in Cardiology and Cardiovascular Disorders on December 29, 2020| Leave a Comment »

Diagnostic and Interventional Cardiology (DAIC): 2020 Top 25 Best Performing Articles Reporter: Aviva Lev-Ari, PhD, RN Here are the top 25 best performing articles on the Diagnostic and Interventional Cardiology (DAIC) website from 2020. This is based on the analytics of DAIC’s record 3.3 million pages views in 2020: 1. Kawasaki-like Inflammatory Disease Affects Children […]

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SAR-Cov-2 is probably a vasculotropic RNA virus affecting the blood vessels: Endothelial cell infection and endotheliitis in COVID-19

Posted in COVID-19, Population Health Management, Genetics & Pharmaceutical, SAR-Cov-2 a vasculotropic (blood vessels) RNA Virus, SARS-CoV-2, Treatment Protocols for COVID-19, Virus Infective Acute Respiratory Syndrome: SARS-CoV on June 1, 2020| 4 Comments »

SAR-Cov-2 is probably a vasculotropic RNA virus affecting the blood vessels: Endothelial cell infection and endotheliitis in COVID-19 Reporter: Aviva Lev-Ari, PhD, RN – Bold face and colors are my addition From: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Reply-To: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Date: Tuesday, June 2, 2020 at 8:50 AM To: Aviva Lev-Ari <aviva.lev-ari@comcast.net> Subject: Re: […]

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WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com

Posted in Cancer and Current Therapeutics on July 30, 2020| 7 Comments »

WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN Introduction (From Cancer Volume 1): Cancer […]

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Tumor Associated Macrophages: The Double-Edged Sword Resolved?

Posted in Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Immuno-Oncology & Genomics, tagged Adaptive immune system, Biology, breast cancer, Cancer - General, Cancer immunology, Cell Biology, Conditions and Diseases, gene expression, genomics, macrophages, modulation of tumor tolerance, research, Stem cell, tumor associated macrophage, tumor microenvironment, Weill Cornell on September 15, 2015| 3 Comments »

Tumor Associated Macrophages: The Double-Edged Sword Resolved? Writer/Curator: Stephen J. Williams, Ph.D. UPDATED 10/04/2021 TAMs Enhance Tumor Hypoxia and Aerobic Glycolysis Cell-based immunity is vital for our defense against pathologic insult but recent evidence has shown the role of cell-based immunity, especially macrophages to play an important role in both the development and hindrance of […]

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Voices of Physicians at Hospitals Caring for Coronavirus Pandemic

Posted in on March 26, 2020|

1/17/2021 Five Countries, Five Experiences of the Pandemic Citizens from around the world share their coronavirus stories. Reporter: Gail S. Thornton, M.A. By Dhruv KhullarJanuary 17, 2021 SOURCE: https://www.newyorker.com/science/medical-dispatch/five-countries-five-experiences-of-the-pandemic?utm_source=nl ### 11/17/2020 Multi-dimensional factors driving the pandemic and how their impact decides any return to the pre- COVID-19 world! Reporter: Gail S. Thornton, M.A. Published on October […]

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Voices of Global Citizens: Impact of The Coronavirus Pandemic, Gail S. Thornton, M.A. Lead Curator – e–mail Contact: gailsthornton@yahoo.com

Posted in on March 18, 2020|

Voices of Global Citizens: Impact of The Coronavirus Pandemic Gail S. Thornton, M.A. Lead Curator – e–mail Contact: gailsthornton@yahoo.com Voices of Patients Tested Positive to Coronavirus Infections in the US Voices of Nurses and Allied Health Care Professionals in the US in the Coronavirus Pandemic Voices of Physicians at Hospitals Caring for Coronavirus Pandemic Voices of Americans during […]

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Immune System Stimulants: Articles of Note @pharmaceuticalintelligence.com

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Signaling & Cell Circuits, Chemical Genetics, Gene Regulation, Gene Regulation and Evolution, Genetics & Innovations in Treatment, Genome Biology, Immuno-Oncology & Genomics, Immunodiagnostics, Immunology, Innovation in Immunology Diagnostics, Viral diseases, tagged Current methods of immune oncotherapy, Evolving approaches including combination oncotherapy, Immunogenetics in oncotherapy, Immunotherapy MarketX, Microbiological factors in cancer growth, New approaches to immunotherapy, Signaling pathways in oncotherapy on May 1, 2016| Leave a Comment »

Immune System Stimulants: Articles of Note @pharmaceuticalintelligence.com Curators: Larry H. Bernstein, MD, FCAP and Aviva Lev-Ari, PhD, RN New Approaches to Immunotherapy New Class of Immune System Stimulants: Cyclic Di-Nucleotides (CDN): Shrink Tumors and bolster Vaccines, re-arm the Immune System’s Natural Killer Cells, which attack Cancer Cells and Virus-infected Cells Three Methods for […]

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Are CXCR4 Antagonists Making a Comeback in Cancer Chemotherapy?

Posted in Cancer - General, Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Immunology, Immunotherapy, Pharmaceutical Drug Discovery, tagged cancer immunotherapeutics, Cancer stem cell, Chemokine, Chemokine receptor, CXCR4, NSCLC on December 15, 2015| Leave a Comment »

Are CXCR4 Antagonists Making a Comeback in Cancer Chemotherapy? Reporter: Stephen J. Williams, Ph.D. Biospace News reported that Massachusetts based X4 Pharmaceuticals is using $34B to launch two clinical trials on its CXCR4 inhibitor X4P-001 in refractory clear cell renal cell carcinoma and refractory epithelial ovarian cancer. The full report is below: X4 Pharma Uses […]

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Oncolytic Virotherapy for Pancreatic Cancer: Overcoming Obstacles in Oncolytic Virus Delivery

Posted in Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Vaccines: Targeting Cancer Genes for Immunotherapy, Cell death pathways, Drug Delivery Platform Technology, Immune Engineering, Immuno-Oncology & Genomics, Immunology, Oncolytic virus & OncoViro-Therapy, Pharmacodynamics and Pharmacokinetics, Translational Research, virology, tagged HSV, Pancreatic cancer, Poxviruses, virotherapy, virus delivery on July 24, 2016| Leave a Comment »

Oncolytic Virotherapy for Pancreatic Cancer: Overcoming Obstacles in Oncolytic Virus Delivery Reporter: Aviva Lev-Ari, PhD, RN We covered MGH’s Innovation on Tumor targeted therapy in Pancreatic Cancer in Pancreatic Cancer Targeted Treatment? Curator: Larry H. Bernstein, MD, FCAP https://pharmaceuticalintelligence.com/2016/05/18/pancreatic-cancer-targeted-treatment/ Below, we report on the State of the Science for Overcoming Obstacles in Oncolytic Virus […]

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Principles of Gene Editing

Posted in Clinical & Translational, Clinical Genomics, CRISPR/Cas9 & Gene Editing, Curation, Genome Biology, Genomic Testing: Methodology for Diagnosis, tagged CRISPR/Cas9, DNA repair, DNA synthesis, gene editing on October 30, 2015| Leave a Comment »

Principles of Gene Editing Larry H. Bernstein, MD, FCAP, Curator LPBI EDITING Researchers are learning how to use synthetic RNA sequences to control the cutting of any piece of DNA they choose. The cell will repair the cut, but an imperfect repair may disable the gene. Or a snippet of different DNA can be inserted […]