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Diagnostic and Interventional Cardiology (DAIC): 2020 Top 25 Best Performing Articles Reporter: Aviva Lev-Ari, PhD, RN   Here are the top 25 best performing articles on the Diagnostic and Interventional Cardiology (DAIC) website from 2020. This is based on the analytics of DAIC’s record 3.3 million pages views in 2020: 1. Kawasaki-like Inflammatory Disease Affects Children […]

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SAR-Cov-2 is probably a vasculotropic RNA virus affecting the blood vessels: Endothelial cell infection and endotheliitis in COVID-19 Reporter: Aviva Lev-Ari, PhD, RN – Bold face and colors are my addition From: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Reply-To: “Dr. Larry Bernstein” <larry.bernstein@gmail.com> Date: Tuesday, June 2, 2020 at 8:50 AM To: Aviva Lev-Ari <aviva.lev-ari@comcast.net> Subject: Re: […]

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WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN Introduction (From Cancer Volume 1): Cancer […]

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Tumor Associated Macrophages: The Double-Edged Sword Resolved? Writer/Curator: Stephen J. Williams, Ph.D. UPDATED 10/04/2021 TAMs Enhance Tumor Hypoxia and Aerobic Glycolysis Cell-based immunity is vital for our defense against pathologic insult but recent evidence has shown the role of cell-based immunity, especially macrophages to play an important role in both the development and hindrance of […]

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1/17/2021 Five Countries, Five Experiences of the Pandemic Citizens from around the world share their coronavirus stories. Reporter: Gail S. Thornton, M.A. By Dhruv KhullarJanuary 17, 2021 SOURCE: https://www.newyorker.com/science/medical-dispatch/five-countries-five-experiences-of-the-pandemic?utm_source=nl ### 11/17/2020 Multi-dimensional factors driving the pandemic and how their impact decides any return to the pre- COVID-19 world! Reporter: Gail S. Thornton, M.A. Published on October […]

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Voices of Global Citizens: Impact of The Coronavirus Pandemic Gail S. Thornton, M.A.  Lead Curator – e–mail Contact:  gailsthornton@yahoo.com    Voices of Patients Tested Positive to Coronavirus Infections in the US Voices of Nurses and Allied Health Care Professionals in the US in the Coronavirus Pandemic Voices of Physicians at Hospitals Caring for Coronavirus Pandemic Voices of Americans during […]

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Immune System Stimulants: Articles of Note @pharmaceuticalintelligence.com Curators: Larry H. Bernstein, MD, FCAP and Aviva Lev-Ari, PhD, RN   New Approaches to Immunotherapy   New Class of Immune System Stimulants: Cyclic Di-Nucleotides (CDN): Shrink Tumors and bolster Vaccines, re-arm the Immune System’s Natural Killer Cells, which attack Cancer Cells and Virus-infected Cells Three Methods for […]

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Are CXCR4 Antagonists Making a Comeback in Cancer Chemotherapy? Reporter: Stephen J. Williams, Ph.D. Biospace News reported that Massachusetts based X4 Pharmaceuticals is using $34B to launch two clinical trials on its CXCR4 inhibitor X4P-001 in refractory clear cell renal cell carcinoma and refractory epithelial ovarian cancer. The full report is below: X4 Pharma Uses […]

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Oncolytic Virotherapy for Pancreatic Cancer: Overcoming Obstacles in Oncolytic Virus Delivery Reporter: Aviva Lev-Ari, PhD, RN   We covered MGH’s Innovation on Tumor targeted therapy in Pancreatic Cancer in Pancreatic Cancer Targeted Treatment? Curator: Larry H. Bernstein, MD, FCAP https://pharmaceuticalintelligence.com/2016/05/18/pancreatic-cancer-targeted-treatment/   Below, we report on the State of the Science for Overcoming Obstacles in Oncolytic Virus […]

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Principles of Gene Editing Larry H. Bernstein, MD, FCAP, Curator LPBI EDITING  Researchers are learning how to use synthetic RNA sequences to control the cutting of any piece of DNA they choose. The cell will repair the cut, but an imperfect repair may disable the gene. Or a snippet of different DNA can be inserted […]

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