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Nobel Laureate Jack Szostak Previews his Plenary Keynote for Drug Discovery Chemistry

Reporter: Aviva Lev-Ari, PhD, RN

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Drug Discovery Chemistry

Optimizing Small Molecules for Tomorrow’s Therapeutics

April 16-18, 2013 | San Diego, CA

Conference Brochure

http://www.drugdiscoverychemistry.com/uploadedFiles/Drug_Discovery_Chemistry/13/2013-Drug-Discovery-Chemistry-Brochure.pdf

Nobel Laureate Jack Szostak to Present Plenary Keynote at Eighth Annual Drug Discovery Chemistry Conference on April 16 – Record Attendance from More than 225 Organizations and 25 Countries is Expected

Drug Discovery Chemistry is one of the few conferences for medicinal chemists working in pharma and biotech, and is focused on discovery and optimization challenges of small molecule drug candidates. New this year are Constrained Peptides and Macrocyclics and GPCR-Based Drug Design which represent areas of chemistry where evolving technologies are leading to renewed interest. They complement the most popular meetings from the past few years: Anti-Inflammatories, Fragment-Based Drug Discovery, Kinase Inhibitor Chemistry and Protein-Protein Interactions:

 – Anti-Inflammatories  [View Agenda] 4/16-17

– Fragment-Based Drug Discovery  [View Agenda] 4/16-17

– Constrained Peptides and Macrocyclics Drug Discovery  [View Agenda] 4/16-17

– Kinase Inhibitor Chemistry  [View Agenda] 4/17-18

– Protein-Protein Interactions  [View Agenda] 4/17-18

– GPCR-Based Drug Design  [View Agenda] 4/17-18

In a recent interview with Bio-IT World’s Kevin Davies, Dr. Szostak shared his thoughts on evolutionary chemistry, cyclic peptides, discovery of new small molecules for therapeutics, and his upcoming plenary keynote address: mRNA Display: From Basic Principles to Macrocycle Drug Discovery.

MEDIA GALLERY: VIDEOS

Jack Szostak Previews his Plenary Keynote for Drug Discovery Chemistry on

mRNA Display: From Basic Principles to Macrocycle Drug Discovery.

VIEW VIDEO

Jack Szostak Previews his Plenary Keynote for Drug Discovery Chemistry

In a recent interview, nobel laureate Dr. Jack Szostak shared his thoughts with Bio-IT World’s Kevin Davies on evolutionary chemistry, cyclic peptides, discovery of new small molecules for therapeutics, his upcoming plenary keynote address, and much more. On April 16, at the Eighth Annual Drug Discovery Chemistry conference, Dr. Szostak will present mRNA Display: From Basic Principles to Macrocycle Drug Discovery.

For VIDEO of Doug Treco Discusses Constrained Peptides and Macrocyclics

SCROLL DOWN THE SAME PAGE AS THE PREVIOUS VIDEO

VIEW VIDEO

Dr. Doug Treco, president & CEO of Ra Pharmaceuticals, shares recent developments in constrained peptides, macrocyclics, and how to develop peptides into a more useful class of drug. Dr. Treco will present Direct Selection of Cyclomimetics™ from mRNA Display Libraries at the Eighth Annual Drug Discovery Chemistry conference in San Diego on April 17.

List of Attendees:

Record Attendance Expected this Year! Should your Organization be on this List?
(Partial List as of 4/5)

A Star – Head – Organic Chemistry
Abbvie – Scientist – Research
Abbvie Bioresearch Ctr – Sr Scientist III – Chemistry
Abbvie Bioresearch Ctr – Sr Scientist III
AbbVie Inc – Principal Research Scientist
AbbVie Inc – Sr Scientist III – Molecular Modeling
Actelion Pharmaceuticals Ltd – Lab Head – Medicinal Chemistry
Actelion Pharmaceuticals Ltd – Sr Lab Head
Activ Motif – PostDoctoral Assoc
Addex Therapeutics – Assoc Res Dir – Structural Science
Adnexus a Bristol Myers Squibb R&D Co – Staff Scientist – Discovery
Affymax Inc – Sr Scientist II
Aileron Therapeutics Inc – Sr VP & CSO
Ajinomoto Co Ltd – Sr. Researcher
Allergan Inc – Sr Scientist – Medicinal Chemistry
Amakem NV – CoFounder & Dir External R&D – External R&D
Ambrx Inc – CTO
Amgen Inc – Principal Scientist – Pharmacokinetics & Drug Metabolism
Amgen Inc – Sr Scientist – Protein Technologies
AMRI – Dir Discovery R&D – Chemistry
AnalytiCon Discovery LLC – Exec VP Bus Dev – Natural Products
Anaspec Inc – Sr Chemist
Ardea Biosciences Inc – VP Research – Research Operations
Arena Pharmaceuticals – Research Fellow
Argenta Discovery 2009 Ltd – Sr Dir Chemistry
ARIAD Pharmaceuticals Inc – Assoc Dir Chemistry
Array BioPharma Inc – Sr Dir Cellular & Translational Biology
Asahi Kasei Pharma Co Ltd – Researcher – Lab for Medicinal Chemistry
Astellas – Scientist – Drug Discovery Research
Astellas Research Institute of American LLC – Principal Scientist – Med Chem
AstraZeneca – Assoc Principal Scientist – R&I iMed Medicinal Chemistry
AstraZeneca R&D Moelndal – Project Leader & Principal Scientist – Medicinal Chemistry & CVGI iMed
Axikin Pharmaceuticals Inc – Sr Dir Drug Dev Technologies – Drug Dev Technologies
Bayer AG – Principal Scientist
Bayer HealthCare AG – Computational Chemistry
Beijing Hanmi Pharmaceutical Co Ltd – Grp Leader Medicinal Chemistry & Analytical Chem
Ben Gurion Univ – Assoc Prof – Microbiology & Immunology & Health Sciences
Bicycle Therapeutics Ltd – CSO
Bio Rad Labs – Sales Mgr
Biogen Idec Inc – Principal Scientist – Physical Biochemistry
Biogen Idec Inc – Principal Scientist
Biogen Idec Inc – Scientist II – Medicinal Chemistry & Drug Discovery
Biogen Idec Inc – Sr Scientist & Medicinal Chemist
Biotage LLC – Specialist – Peptide Applications
Boehringer Ingelheim Pharma – Principal Scientist – Structural Research
Boehringer Ingelheim Pharma – Sr Principal Scientist – Medicinal Chemistry
Boehringer Ingelheim Pharma – Sr Scientist – Medicinal Chemistry
Boehringer Ingelheim Pharma GmbH & CO KG – Scientist – Chemical Research
BPS Bioscience Inc – Sr Research Scientist I
Brigham & Womens Hospital – Asst Prof Neurology
Bristol Myers Squibb – Grp Leader – Medicinal Chemistry
C&C Research Labs – Sr Research Scientist – Medicinal Chemistry
C&C Research Labs – Sr Researcher – CADD
Cancer Research UK Beatson Labs – Head – Chemistry
Catholic Univ of Korea – Prof – Natl Lab for Molecular Virology
Celgene – Assoc Scientist – Chemistry
Celgene – Sr Scientist – Chemistry
Celgene Avilomics Research – Sr Dir Chemistry
Celgene Corp – Sr Principal Investigator – Translational Dev
Cell Assay Innovations LLC – Founder & President
Charnwood Molecular Ltd – Head – Medicinal Chemistry
Charnwood Molecular Ltd – Mgr – Bus Dev
ChemAxon – Account Mgr
ChemAxon Ltd – Dir – Sales
ChemAxon Ltd – Principal Application Scientist
ChemBridge Corp – Exec Dir Sales & Marketing
Chemical Computing Group Inc – Principal Scientist – Scientific Support
Chinese Academy of Science – Guangzhou Institute of Biomedicine & Health
Chugai Pharmaceutical Co Ltd – Medicinal Chemist – Research
Chugai Pharmaceutical Co Ltd – Researcher
City of Hope Beckman Research Institute – Prof – Immunology
City of Hope Natl Medical Ctr – Staff Scientist – Molecular Medicine
CMD Bioscience LLC – Dir – Bus Dev
CMD Bioscience LLC – Dir Computational Chemistry
CNRS – Principal Investigator – Cancer Research
CNRS IPBS – Chemistry
Computype Inc – Market Mgr – Life Sciences
Computype Inc – Regional Sales Mgr
Cubist Pharmaceuticals Inc – Sr Scientist – Discovey Chemistry
Daiichi Sankyo Co Ltd – Assoc Sr Researcher – Discovery Research Lab
Daiichi Sankyo Co Ltd – Assoc Sr Researcher – Lead Discovery & Optimization Research Labs I
Daiichi Sankyo Co Ltd – Sr Dir – Lead Discovery & Optimization Research Labs I
Dart NeuroScience LLC – Assoc Dir – Chemistry
Dart NeuroScience LLC – Assoc Dir Chemistry
Dart NeuroScience LLC – Scientist II
Dart NeuroScience LLC – Scientist III – Leade Discovery HTS
Dart NeuroScience LLC – Scientist III
Dart NeuroScience LLC – Senior Research Assoc – Chemistry
Dart NeuroScience LLC – Sr Research Assoc – Chemistry
DEL BioPharma – Owner
DiscoveRx Corp – Dir Marketing – LeadHunter
DiscoveRx Corp – Sr Product Mgr
Dong A Pharmaceutical Co Ltd – Research Scientist
Dotmatics Ltd
E Merge Tech Global Svcs – CEO
E Merge Tech Global Svcs – Mgr – R&D
Eisai Co Ltd – Researcher – Product Creation
Eli Lilly & Co – Computational Chemist & Crystallographer
Eli Lilly & Co – Endocrine
Eli Lilly & Co – Sr Advisor – DCR&T
Eli Lilly & Co – Sr Research Advisor – Discovery Chemistry
Eli Lilly & Co – Sr Research Advisor – Discovery Chemistry Research
Eli Lilly & Co – Sr Research Scientist – Discovery Chemistry
EMD Serono Research & Development Institute Inc – Chemistry
EMD Serono Research & Development Institute Inc – Head – Drug Target Innovation & External Innovations
EMD Serono Research & Development Institute Inc – Sr Scientist – Chemistry
EMD Serono Research & Development Institute Inc – Sr Scientist – Medicinal Chemistry
Emory Univ – Post Doc Fellow
Ensemble Therapeutics – CSO
Entelos Inc – Dir Marketing
ESBS – Research Dir Receptord & Membrane Proteins – CNRS Biotechnology
ETH Zurich – Sr Scientist – Pharmaceutical Sciences
Evotec Inc – Project Leader – Discovery
Ewha Womans University – Prof
F Hoffmann La Roche Inc – Consultant – Medical Affairs
F Hoffmann La Roche Inc – Sr Research Leader – PR&D Discovery Chemistry
F Hoffmann La Roche Inc – VP & Global Head of Discovery Technologies – pRED & Discovery Technologies
Ferring Research Institute – Sr Scientist – Medicinal Chemistry
FLAMMA – Dir – Bus Dev
Full Spectrum Genetics Inc – Head – Bioinformatics
GE Healthcare – Product Specialist
Genentech Inc – Assoc Dir Structural Biology
Genentech Inc – Postdoc Research Fellow – Structural Biology
Genentech Inc – Scientist – Medicinal Chemistry
Genentech Inc – Scientist – Protein Engineering
Genentech Inc – Scientist & Team Leader – Medicinal Chemistry
Genentech Inc – Sr Mgr – Bus Dev
Genomics Institute of the Novartis Research Foundation – Principal Investigator – Structural Biology
Gilead Sciences Inc – Dir Biology
Gilead Sciences Inc – Dir Medicinal Chemistry
Gilead Sciences Inc – Research Scientist II
GL Chemtech Intl Ltd – Dir Bus Dev
Gwangju Institute of Science & Technology – Prof – Life Sciences
Harvard Medical School – Hematology Oncology
Hauptman Woodward Institute – Sr Research Scientist – Structural Biology
Helmholtz Zentrum Muenchen GmbH – Head – Assy Dev & Sxcreening Platform
Helsinn Therapeutics Inc – Sr Assoc – Tech Affairs
Heptares Therapeutics Ltd – Head – Biomolecular Structure
Hewlett Packard Oregon
Imgenex Corp – Principal Consultant – Corp Dev
Imgenex Corp – Product Mgr – Marketing
In Silico Biosciences – CSO – Computational Neuropharmacology
Indiana University – Research Asst Prof – Biochemistry & Molecular Biology
Industry Canada – Sr Patent Examiner – Organic 02
INSERM – Principal Investigator – CRCM CNRS
INSERM – Prof
Integral BioSciences – Research Scientist – Med Chem
Iowa State University – Principal Investigator – Biomedical Sciences
Ironwood Pharmaceuticals Inc – MedChem
Janssen Pharmaceuticals Inc – Sr Scientist – Scale Up Synthesis
Japan Tobacco Inc – Research Scientist – Central Pharmaceutical Research Lab
Japan Tobacco Inc – Researcher
Japan Tobacco Inc – Sr Dir Project & Portfolio Mgmt – Project & Portfolio Mgmt
Johns Hopkins University – Prof – Biology
Johnson & Johnson Pharmaceutical R&D – Assoc Scientist – Chemistry
Johnson & Johnson Pharmaceutical R&D – Chemist – Med Chem
Johnson & Johnson Pharmaceutical R&D – Physiological Systems
Johnson & Johnson Pharmaceutical R&D – Principal Scientist – Immunology Chemistry
Johnson & Johnson Pharmaceutical R&D – Sr Scientist – Chemistry
JT Central Pharmaceutical Research Institute – Research Scientist – Chemistry
Jubilant Discovery
Kalexsyn Inc
King Saud University – Pharmaceutical Chemistry
Korea Research Institute of Chemical Technology – Principal Researcher Drug Discovery Research
Lexicon Pharmaceuticals – Assoc Dir – Chem Tech
Life Chemicals Inc – Mgr – Bus Dev & Sales
Life Chemicals Inc – VP Marketing & Sales
LipoScience – CSO
Los Alamos Natl Lab – PostDoc Research Assoc – Bioscience
Lundbeck Research USA – Principal Scientist – Discovery Chemistry & DMPK
Massachusetts General Hospital – Prof – Genetics
Mayo Clinic – Asst Prof – Immunology
Medivation Inc – Dir Medicinal Chemistry
Merck – Principal Scientist
Merck Serono Research – Sr Dir Lead Discovery Technologies – MS DTC Strategic Operations Global Tech
Mitsubishi Tanabe Pharma Corp – Research Scientist – Medicinal Chemistry
MorphoSys AG – Sr Scientist
Natl Institute of Biological Science – Sr Investigator
Natl Taiwan University – Research Assoc – Chemisty
Natl Univ of Singapore – Assoc Prof – Chemistry
NIH CIT – CIO & Dir
NIH NCATS – Research Scientist – Probe Dev Ctr
NIH NINDS – Investigator – Basic Neuroscience
Novartis Institute for Tropical Diseases Pte Ltd – Investigator III – Chemistry
Novartis Institutes for BioMedical Research Inc – Dir Bus Dev
Novartis Institutes for BioMedical Research Inc – Presidential Postdoctoral Fellow
Novartis Pharma AG – Investigator III – Global Discovery Chemistry
Novartis Pharma AG – Proteomic Chemistry
Novartis Pharma AG – Research Investigator – NIBR
Nuevolution AS – Research Scientist
Nuevolution AS – Sr Scientist – Molecular Design
Oncodesign SA – CSO
Onyx Scientific Ltd – Dir Bus Dev
OpenEye Scientific Software Inc – Dir Emerging Markets – Emerging Markets
OpenEye Scientific Software Inc – Sr Applications Scientist
Ora Inc – Dir Pre Clinical Svcs
Original Biomedical Corp – Bus Dev
Peptron Inc – CEO
Pfizer Animal Health – Sr Principal Scientist
Pfizer Global R&D Groton Labs – Sr Principal Scientist – Structure Biology & Biophysics
Pfizer Inc – Assoc Dir – Prizer Animal Health
Pfizer Inc – Assoc Research Scientist – Chemical Sciences
Pfizer Inc – VP Chemistry
Pfizer Research Labs – Principal Scientist – Worldwide Medicinal Chemistry
PharmaCore Inc – Dir Bus Dev
PharmaCore Inc – President
Pharmacyclics Inc – Research Scientist III – Medicinal Chemistry
Polish Academy Of Sciences – Institute of Organic Chemistry
Polyphor Ltd – CSO & CoFounder
POSTECH – Assoc Prof
Prestwick Chemical – Head – Medicinal Chemistry
Prestwick Chemical – VP US Operations
Principia BioPharma Inc – Assoc Dir
Protagonist Therapeutics Inc – President & CEO
Purdue University – Assoc Prof – Medicinal Chemistry & Molecular Pharmacology
Quantum Tessera Consulting LLC – President and CSO
RA Pharmaceuticals Inc – President & CEO
RA Pharmaceuticals Inc – Scientist II
Receptos Inc – Assoc Dir – Biology
Receptos Inc – Dir Structural Biology
Receptos Inc – Scientist I
Roche Diagnostics GmbH – Dir Bio Analysis – Antibody Dev
Roche NimbleGen Inc – Sr Scientist
Rockefeller University – Richard M & Isabel P Furlaud Prof – Molecular Biology & Biochemistry
Rutgers University – Asst Research Prof – CABM
Sanofi Aventis – Head – In Silico Drug Discovery
sanofi aventis Grp – Project Leader
Santen Pharmaceutical – Researcher – Synthetic Chemistry Group
Schrodinger Inc – Applications Scientist
Science for Solutions LLC – President
Scripps Research Institute – Asst Prof – Molecular Biology
Scripps Research Institute – PostDoc Assoc – Molecular Therapeutics
Scripps Research Institute – Prof – Chemical Physiology
Scripps Research Institute – Research Assoc – Chemistry
Scripps Research Institute – Visiting Scientist – Chemical Physiology
Selcia Ltd – Grp Leader – Biology
Senomyx Inc – Principal Scientist – Chemistry
SENSIQ – COO
SENSIQ – CSO – Bioinstrumentation
SENSIQ – VP Marketing – Sales & Marketing
Shionogi & Co Ltd
SIGA Technologies Inc – CSO
Simulations Plus Inc – Research Fellow – Life Sciences
Simulations Plus Inc – Team Leader – Cheminformatics Study
Sookmyung Womens University – Student – College of Pharmacy
SRI Intl – Program Dir Medicinal Chemistry
St Jude Childrens Research Hospital – Post Doc Fellow – Chemical Biology & Therapeutics
St Jude Childrens Research Hospital – Postdoc – Chem Bio & Therapeutics
St Jude Childrens Research Hospital – Research Asst – Chemical Biology & Therapeutics
St Petersburg State Institute of Technology – Lab of Molecular Pharmacology
Stanford University – Assoc Prof – Bioengineering
Stanford University – Graduate Student – Kobilka Lab
Stanford University – Research Assoc – Chemical & Systems Biology
Structural Genomics Consortium – Postdoc Research Assoc – Epigenetics Probes Team
Sygene Intl Ltd – Sr Lead Investigator – Medchem
Sygnature Discovery Ltd – CEO
Sygnature Discovery Ltd – Dir New Bus Dev
SYNthesis Shanghai – Managing Dir
Synthonix – Bus Dev Mgr
Synthonix – CoFounder & President & CEO
Taiho Pharmaceutical Co Ltd – Sr Scientist – Medicinal Chemistry
Takeda California – Assoc Scientist
Takeda California – Scientist – Discovery Biology
Takeda California – Sr Scientist – Chemistry
Takeda California – Sr Scientist – SB & Ab Core Science & Technology
Takeda Pharmaceutical Co Ltd – Principal Scientist – Structural Biology
Takeda Pharmaceutical Co Ltd – Researcher – Medicinal Chemistry Lab
Takeda Pharmaceutical Co Ltd – Researcher – Pharmaceutical Research
Takeda San Diego – Dir Immunology Chemistry
Takeda San Diego – Scientist II
TC Scientific Inc – CEO
Theravance Inc – Research Assoc – Medicinal Chemistry
Theravance Inc – Scientist – Med Chem
Theravance Inc – Sr Research Advisor – Medicinal Chemistry
Theravance Inc – VP Molecular & Cellular Biology
Thermo Fisher Scientific Inc – Bus Mgr
Topharman USA
Tranzyme Pharma Inc – Sr VP Research & Preclinical Dev
Tranzyme Pharma Inc – VP IP & Operations
Tsinghua Univ – Medicinal Chemistry
UCB Pharma – Principal Scientist – CADD
UCB Pharma – Computational Medicinal Chemist
University of California Los Angeles – Prof – Molecular Imaging
University of California San Diego – Asst Prof – Chemistry & Biochemistry
University of California San Diego – Postdoc – Chemistry & Biochemistry
University of California San Diego – Prof – Clinical Medicine & Rheumatology
University of California San Diego – Prof – Molecular Biology
University of California San Francisco – Assoc Adjunct Prof – Lab Medicine
University of Central Florida – GRA – Chemistry
University of Cincinnati – Assoc Prof – Environmental Health
University of Essex – Prof – Computational Chemistry
University of Illinois Chicago – Prof – Biopharmaceutical Sciences
University of Maryland Baltimore – Grollman Glick Prof – Pharmaceutical Sciences
University of Miami – Dir Drug Discovery – Diabetes Research Institute
University of Navarra – Dir – Small Molecule Discovery
University of New South Wales – Postgraduate Student – Chemistry
University of Paris Diderot – Sr Research Assoc – Inserm UMR S973
University of Pittsburgh – Prof & Chair – Microbiology & Molecular Genetics
University of Pittsburgh – Research Asst Prof – Computational & Systems Biology
University of Southern California – Assoc Prof – Pharmacology & Pharmaceutical Sciences
University of Southern California – Scientist – Molecular & Computational Biology
University of Southern California – Molecular Microbiology & Immunology
University of Texas Dallas – Assoc Prof – Psychiatry & Neurology & Neurotherapeutics
University of Texas Houston – Asst Prof – Stem Cell Research
University of Toronto – Principal Investigator – Medical Biophysics
University of Utah – Research Assoc
University of Warsaw – Institute of Genetics and Biotechnology
University of York – Prof – Chemistry
University of Zurich – Scientist – Biochemistry
University Pompeu Fabra – Research Assoc – Medicinal Chemistry
Vanderbilt University – Research Fellow – Ctr for Neuroscience Drug Discovery
Vertex Pharmaceuticals Inc – Med Chem
Vertex Pharmaceuticals Inc – Research Fellow II – Biology
Vertex Pharmaceuticals Inc – Research Scientist – Chemistry
Vertex Pharmaceuticals Inc – Research Scientist I – Biology
Vidya Bharati College – Asst Prof – Chemistry
Vrije University Brussels – Exec Dir & Prof – Mol & Cellular Interactions
Vrije University Brussels – Prof Research Grp of Organic Chemistry – Bioengineering Sciences & Chemistry
Wayne State University – Research Scientist – Pathology & Oncology
Wichita State University – WSU Foundation Distinguished Prof – Chemistry
Wistar Institute – Staff Scientist
WuXi AppTec – Dir Bus Dev – Chemistry Svcs
X Chem Pharmaceuticals Inc – Dir Chemistry
X Chem Pharmaceuticals Inc – Sr Dir Lead Discovery
Yale University – Assoc Prof – Lab Medicine & Pharmacology
Yonsei University – Prof – Biochemistry
Yonsei University – Prof – Biotechnology