Plant-based Nutrition, Neutraceuticals and Alternative Medicine: Article Compilation the Journal PharmaceuticalIntelligence.com
Curator: Larry H. Bernstein, MD, FCAP
- Green tea polyphenols alleviate early BBB damage
http://pharmaceuticalintelligence.com/2013/07/31/green-tea-polyphenols-alleviate-early-bbb-damage-during/ - What do you know about Plants and Neutraceuticals?
Author and Curator, Larry H. Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/30/what-do-you-know-about-plants-and-neutraceuticals/
- The Final Considerations of the Role of Platelets and Platelet Endothelial Reactions in Atherosclerosis and Novel Treatments
Author and Curator: Larry H Bernstein, MD, FCAP
- Endothelial Function and Cardiovascular Disease
Author and Curator: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2012/10/25/endothelial-function-and-cardiovascular-disease/
- NO Nutritional remedies for hypertension and atherosclerosis. It’s 12 am: do you know where your electrons are?
Author and Reporter: Meg Baker, Ph.D., Registered Patent Agent
- Cocoa and Heart Health
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2013/11/17/cocoa-and-heart-health/
- Metabolomics: its applications in food and nutrition research
Reporter and Curator: Dr. Sudipta Saha, Ph.D.
- Japanese knotweed extract (Polygonum cuspidatum) Resveratrol 98%
Reporter: Larry H Bernstein, MD, FCAP Stanford Lee, Shanghai Natural Bio-engineering Co., Ltd
Key products: resveratrol, curcumin,artemisinin,artemether,artesunate,dihydroartemisinin,Lumefantrine,etc
https://www.linkedin.com/today/post/article/20140805055958-283555965-japanese-knotweed-extract-polygonum-cuspidatum-resveratrol-98?/
- Antimicrobial resistance
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/08/18/antimicrobial-resistance/ - Macrocycles in new drug discovery
Reporter: Larry H Bernstein, MD, FCAP Jamie Mallinson, Ian Collins
Future Medicinal Chemistry, Jul 2012, Vol. 4, No. 11, Pages 1409-1438.
Natural product macrocycles and their synthetic derivatives
http://pharmaceuticalintelligence.com/2014/08/16/macrocycles-in-new-drug-discovery/
- Lipid Metabolism
ALA and LA, LCPUFAs (EPA, DHA, and AA), eicosanoids, delta-3-desaturase, prostaglandins, leukotrienes
Ginseng fights fatigue in cancer patients, Mayo Clinic-led study finds http://pharmaceuticalintelligence.com/2014/08/15/lipid-metabolism/
- Ginseng fights fatigue in cancer patients, Mayo Clinic-led study finds
Reporter: Larry H Bernstein, MD, FCAP
- Scientists develop new cancer-killing compound from salad plant / 1,200 times more specific in killing certain kinds of cancer cells than currently available drugs
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/17/scientists-develop-new-cancer-killing-compound-from-salad-plant-1200-times-more-specific-in-killing-certain-kinds-of-cancer-cells-than-currently-available-drugs/ - Protein heals wounds, boosts immunity and protects from cancer – Lactoferrin
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/17/protein-heals-wounds-boosts-immunity-and-protects-from-cancer-lactoferrin/ - Inula helenium ( elecampane ) 100% Effective against MRSA in vitro, 200 Strains
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/15/inula-helenium-elecampane-100-effective-against-mrsa-in-vitro-200-strains/ - Thymoquinone, an extract of nigella sativa seed oil, blocked pancreatic cancer cell growth and killed the cells by enhancing the process of programmed cell death.
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/15/thymoquinone-an-extract-of-nigella-sativa-seed-oil-blocked-pancreatic-cancer-cell-growth-and-killed-the-cells-by-enhancing-the-process-of-programmed-cell-death/ - Cinnamon is lethal weapon against E. coli O157:H7
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/15/cinnamon-is-lethal-weapon-against-e-coli-o157h7/ - Garlic compound fights source of food-borne illness better than antibiotics (100 times more effective than two popular antibiotics )
Reporter: Larry H Bernstein, MD, FCAP
- Reference Genes in the Human Gut Microbiome: The BGI Catalogue
Reporter: Aviva Lev-Ari, PhD, RN
- Study suggests consuming whey protein before meals could help improve blood glucose control in people with diabetes
Reporter: Larry H Bernstein, MD, FCAP
http://pharmaceuticalintelligence.com/2014/07/12/study-suggests-consuming-whey-protein-before-meals-could-help-improve-blood-glucose-control-in-people-with-diabetes/ - Omega-3 fatty acids, depleting the source, and protein insufficiency in renal disease
Larry H. Bernstein, MD, FCAP, Curator
http://pharmaceuticalintelligence.com/2014/07/06/omega-3-fatty-acids-depleting-the-source-and-protein-insufficiency-in-renal-disease/ - Health benefit of anthocyanins from apples and berries noted for men
Larry H. Bernstein, MD, FCAP, Curator
http://pharmaceuticalintelligence.com/2014/07/06/health-benefit-of-anthocyanins-from-apples-and-berries-noted-for-men/ - Carrots Cut Men’s Prostate Cancer Risk by 50%
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/07/03/carrots-cut-mens-prostate-cancer-risk-by-50/ - A Recipe To Make Cannabis Oil For A Chemotherapy Alternative
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/07/02/a-recipe-to-make-cannabis-oil-for-a-chemotherapy-alternative/ - Plant flavonoid found to reduce inflammatory response in the brain: luteolin
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/29/plant-flavonoid-found-to-reduce-inflammatory-response-in-the-brain-luteolin/ - Omega-3 fatty acids protect eyes against retinopathy, study finds
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/28/omega-3-fatty-acids-protect-eyes-against-retinopathy-study-finds/ - Scientists identify new pathogenic and protective microbes associated with severe diarrhea
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/28/scientists-identify-new-pathogenic-and-protective-microbes-associated-with-severe-diarrhea/ - 2,000-year-old herb regulates autoimmunity and inflammation / Chang Shan, from a type of hydrangea that grows in Tibet and Nepal
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/27/2000-year-old-herb-regulates-autoimmunity-and-inflammation-chang-shan-from-a-type-of-hydrangea-that-grows-in-tibet-and-nepal/ - Turmeric-based drug effective on Alzheimer flies
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/27/turmeric-based-drug-effective-on-alzheimer-flies/ - Plant flavonoid luteolin blocks cell signaling pathways in colon cancer cells
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/26/plant-flavonoid-luteolin-blocks-cell-signaling-pathways-in-colon-cancer-cells/ - Study Finds Shu Gan Liang Xue Herbal Formula Has Breast Cancer Anti Tumor Effect
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/25/study-finds-shu-gan-liang-xue-herbal-formula-has-breast-cancer-anti-tumor-effect/ - HMPC Q&A Documents on Herbal Medicinal Products published
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/25/hmpc-qa-documents-on-herbal-medicinal-products-published/ - Garden Cress Extract Kills 97% of Breast Cancer Cells in Vitro
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/21/garden-cress-extract-kills-97-of-breast-cancer-cells-in-vitro/ - Moringa Oleifera Kills 97% of Pancreatic Cancer Cells in Vitro
Larry H. Bernstein, MD, FCAP, Reporter
http://pharmaceuticalintelligence.com/2014/06/21/moringa-oleifera-kills-97-of-pancreatic-cancer-cells-in-vitro/
16. The Discovery and Properties of Avemar – Fermented Wheat Germ Extract: Carcinogenesis Suppressor
Larry H. Bernstein, MD, FCAP, Author and Curator
http://pharmaceuticalintelligence.com/2014/06/09/the-discovery-and-properties-of-avemar-fermented-wheat-germ-extract-carcinogenesis-suppressor-2/
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This is very insightful. There is no doubt that there is the bias you refer to. 42 years ago, when I was postdocing in biochemistry/enzymology before completing my residency in pathology, I knew that there were very influential mambers of the faculty, who also had large programs, and attracted exceptional students. My mentor, it was said (although he was a great writer), could draft a project on toilet paper and call the NIH. It can’t be true, but it was a time in our history preceding a great explosion. It is bizarre for me to read now about eNOS and iNOS, and about CaMKII-á, â, ã, ä – isoenzymes. They were overlooked during the search for the genome, so intermediary metabolism took a back seat. But the work on protein conformation, and on the mechanism of action of enzymes and ligand and coenzyme was just out there, and became more important with the research on signaling pathways. The work on the mechanism of pyridine nucleotide isoenzymes preceded the work by Burton Sobel on the MB isoenzyme in heart. The Vietnam War cut into the funding, and it has actually declined linearly since.
A few years later, I was an Associate Professor at a new Medical School and I submitted a proposal that was reviewed by the Chairman of Pharmacology, who was a former Director of NSF. He thought it was good enough. I was a pathologist and it went to a Biochemistry Review Committee. It was approved, but not funded. The verdict was that I would not be able to carry out the studies needed, and they would have approached it differently. A thousand young investigators are out there now with similar letters. I was told that the Department Chairmen have to build up their faculty. It’s harder now than then. So I filed for and received 3 patents based on my work at the suggestion of my brother-in-law. When I took it to Boehringer-Mannheim, they were actually clueless.