Sequencing yourself! and Learn more on Genome Sequencing on Tuesday, November 17, 2015 from 8am-5pm in the Joseph B. Martin Conference Center of the Harvard New Research Building at Harvard Medical School

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Sequencing yourself! and Learn more on Genome Sequencing on Tuesday, November 17, 2015 from 8am-5pm in the Joseph B. Martin Conference Center of the Harvard New Research Building at Harvard Medical School

July 7, 2015 by 2012pharmaceutical

Sequencing yourself! and Learn more on Genome Sequencing on Tuesday, November 17, 2015 from 8am-5pm in the Joseph B. Martin Conference Center of the Harvard New Research Building at Harvard Medical School

Reporter: Aviva Lev-Ari, PhD, RN

Become one of the first humans to have your entire genome sequenced, while participating in an interactive set of presentations and debates about the promise and limitations of genome sequencing from some of the world’s leading genomic scientists.

The UYG Boston is an invitation-only, interactive symposium in which approximately 60 leaders from the Boston business and academic communities will have the opportunity to undergo whole genome sequencing, and to explore their own genome as part of an all-day educational conference with exciting presentations, debates and comments from some of the most thought-provoking leaders in the field of sequencing, informatics and genomic medicine.

Co-sponsors:

Brigham Genome Medicine, Brigham and Women’s Hospital
Partners Personalized Medicine and Laboratory for Molecular Medicine
Precision Medicine Program at Brigham and Women’s Hospital
Department of Pathology at Brigham and Women’s Hospital
Analytic and Translational Genetics Unit, Massachusetts General Hospital
The Broad Institute of Harvard and MIT
Department of Pathology at Massachusetts General Hospital
Division of Genetics, Department of Medicine, Brigham and Women’s Hospital

http://uygboston.uygsymposium.com/

Draft Agenda for UYG Agenda, November 17, 2015, NRB Rotunda Room

Registration is still open at this link: http://uygboston.uygsymposium.com

Breakfast and Registration

7:30-8:30

Module 1: Understanding the Basics of Genetics and Genomics

Moderator: __________________________________

8:30 am -9:55 am

(10) Robert Green: Welcome and Introductory Remarks

(20) Stacey Gabriel: Technical Overview of Sequencing, Alignment and Variant Calling

(20) Heidi Rehm: Variant Classification and Lab Reporting: the Good, the Bad and the VUS

(20) Daniel MacArthur: Using Large Datasets to Explore Penetrance

(15) Questions and Discussion

Coffee Break

9:55 am – 10:10 am

Module 2: Sequencing and Informatics in Clinical Care

Moderator: __________________________________

10:10 am-11:30 noon

(20) Dick Maas: Sequencing in Undiagnosed Cases

(20) Kricket Seidman: Sequencing in the Care of Specific Diseases (Cardiomyopathy)

(20) Zak Kohane: Sequencing and Informatics

(20) Discussion

Luncheon: Understand Your Genome®

11:30 noon – 1:00 pm

Pechet Room

Lunch for those who have been sequenced or wish to learn to use the MyGenome web portal with the demo genome (seating is limited to 40 WGS attendees + 10 additional attendees):

(30) Erica Ramos: Clinical Whole Genome Sequencing in a Healthy Population

(30) Erica Ramos: MyGenome Web Portal Revealed

(30) Erica Ramos and Genetic Counselors: Holding and Exploring Your Own Genome

Lunch served separately for those who do not wish to explore MyGenome Web App

Module 3: Sequencing in Research: from Discovery to Patient Care

Moderator: __________________________________

1:00 pm – 2:40 pm

(10) Jeff Flier: Afternoon welcome and remarks

(20) Sek Kathiresan: Developing Medicines that Mimic Natural Genomic Successes

(20) Calum MacRae: Global Phenotyping and the Clinic of the Future

(10) Heidi Rehm: ClinGen and Matchmaker Exchange

(20) Robert Green: Clinical Outcomes Research in Sequencing

(20) Discussion

Module 4: Academic Medical Centers and Personalized/Precision Medicine

Moderator: __________________________________

2:40- 3:35

(15) Betsy Nabel: Direct-to Consumer Sequencing and the Academic Medical Center

(20) Jeff Golden: Precision Medicine, Regulation and Reimbursement

(20) Discussion

Afternoon Break

3:35-3:50

Module 5: Debate on the Benefits, Harms and Costs of Sequencing Health Individuals by Individual Speakers with the Entire Panel of Speakers and the Attendees

3:50-4:55

Five Minute Pro or Con by Each Speaker and Select Audience Members, Followed by Debate

“DNA Team” Captains: “There is Benefit” Jeff Golden/Jeff Flier

“RNA Team” Captains: “There is No Benefit” Sek Kathiresan/Betsy Nabel

Closing Remarks

4:55 – 5:00

(5) Robert Green

Wine and Cheese Reception for Speakers and Attendees

5:00-6:00

Registration

– See more at: http://personalizedmedicine.partners.org/education/personalized-medicine-conference/program.aspx#sthash.cnydkNG1.dpuf

Fee:

Register by July 15^th to attend for $3,100!
After July 15^thregistration will be $3,500.

Pricing includes:

$2,900 TruGenome™ Predisposition Screen plus a conference registration fee

When:

November 17, 2015
General Session: 8am – 5pm
Reception: 5pm – 7pm

Where:

The Joseph B. Martin Conference Center
Harvard Medical School
77 Avenue Louis Pasteur
Boston, MA 02115

Confirmed Speakers

George Church, PhD,
Harvard Medical School

Stacey Gabriel, PhD
The Broad Institute

Jeff Golden, MD
Brigham and Women’s Hospital

Robert Green, MD, MPH
Brigham and Women’s Hospital

Sek Kathiresan, MD
Massachusetts General Hospital

Zak Kohane, MD, PhD
Harvard Medical School

Richard Maas, MD, PhD
Brigham and Women’s Hospital

Daniel MacArthur, PhD
Massachusetts General Hospital

Calum MacRae, MD
Brigham and Women’s Hospital

Betsy Nabel, MD
Brigham and Women’s Hospital

Heidi Rehm, PhD
Laboratory of Molecular Medicine

Christine Seidman, MD
Brigham and Women’s Hospital

SOURCE

From: Robert Green <rcgreen@genetics.med.harvard.edu>

Date: Tuesday, July 7, 2015 at 1:46 PM

Subject: Learn about genome sequencing by sequencing yourself!

Robert C. Green, MD, MPH

Director, G2P Research Program

Associate Director for Research, Partners Center for Personalized Genetic Medicine

Division of Genetics, Department of Medicine

Brigham and Women’s Hospital and Harvard Medical School

EC Alumnae Building, Suite 301, 41 Avenue Louis Pasteur, Boston, MA 02115

(office) 617-264-5834, (fax) 617-264-3018, (cell) 617-966-3216

(email) rcgreen@genetics.med.harvard.edu

(web) www.g enomes2people.org

Dear Colleagues:

We are inviting you, as one of a small group of forward looking thought leaders, to attend an exciting educational and experiential event: the Boston “Understand your Genome” conference. This conference will take place the day before this year’s Partners Personalized Medicine Conference at Harvard Medical School and will have two components.

First, a panel of world-renowned speakers will discuss the current progress and promise of genomic medicine, and debate the controversial issues surrounding the sequencing of healthy individuals for prediction and prevention.

Second, the conference will provide you with the option to become one of the first people on the planet to have your whole genome sequenced at a CLIA facility where a report will be generated by a board certified molecular geneticist on 1,691 genes with well-established associations to 1,232 Mendelian conditions, and 11 genes associated with responses to 16 different medications.

This conference is a non-profit educational event that is sponsored by the Division of Genetics, in the Department of Medicine at Brigham and Women’s Hospital with co-sponsorship by Partners Personalized Medicine and the Laboratory for Molecular Medicine, the Precision Medicine Program at Brigham and Women’s Hospital, the Department of Pathology at Brigham and Women’s Hospital, the Analytic and Translational Genetics Unit at Massachusetts General Hospital, the Department of Pathology at Massachusetts General Hospital and the Broad Institute. Together, we have assembled a remarkable panel of speakers for the first component of the program.