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Archive for the ‘Materials Science & Engineering’ Category

Holography inspired 3D free space display allows doctors to see a patient’s heart in mid-air during real time medical procedures

Reporter: Danut Dragot, PhD

 

An Israeli firm, http://www.realviewimaging.com/, has developed 3D holographic imaging technology that allows doctors to see a patient’s anatomy “floating” in mid-air during real time medical procedures. The company says successful trials of its system demonstrate that science fiction has become science fact. To properly illustrate its three dimensional, holographic technology, Realview Imaging has produced a video demonstrating what it says an observer would see in an operating theatre. The company says the technology gives surgeons an unprecedented look at their patient’s anatomy as they’re operating. Doctor Elchanan Bruckheimer helped develop it. “Doctors deal with patients. Patients are built of tissues and things that move. If we want to intervene and treat those things, looking at them as they actually are in real life, in real time, is definitely going to improve the way we perform our procedures, how successful we are in those procedures and the time it takes to do those procedures,” Bruckheimer said. The system combines two technologies. Realview’s co-founder Shaul Gelman says it begins with data from X-ray, MRI or ultrasound imaging, reproduced as a 3D hologram. And for doctors like Einat Birk, that makes a difference. “Instead of having two dimensional cuts through the heart we are able to see the heart floating in front of us, we are able to cut through it, to touch it, to see the interaction between the device and the tissue around it. And it was really a wonderful, enlightening experience that we’re never exposed to,” Birk said. RealView says it plans to launch its medical imaging system commerically in 2015. Recent progress on holography allows us to understand how 3D holographic imaging technology works [1-6]. As explained by an Atlanta cardiologist Dr. Randy Martin [7] the heart is an extraordinary machine that he passionately talk about the anatomy and physiology of the heart. The addition of the holographic display in the operating room of a heart surgeon is giving to professionals in the field a new display tool that is continously perfected for the best care of humans and for the more understanding of many intricacies of the human heart.
Source
http://www.ajc.com/news/lifestyles/health/3d-organ-holograms-bring-out-body-experience-surge/ncfKH/
REFERENCES
1. V. M. Bove, “Display Holography’s Digital Second Act,” Proc. IEEE, 100, 4, 918–928 (2012).
2. H. I. Bjelkhagen and D. Brotherton-Ratcliffe, Ultra-Realistic Imaging: Advanced Techniques in Analogue and Digital Colour Holography, Taylor & Francis Group, London, England (2013).
3. J. Khan et al., “A low-resolution 3D holographic volumetric display,” Proc. SPIE, 7723, 77231B-7 (2010).
4. J. Khan et al., “A real-space interactive holographic display based on a large-aperture HOE,” Proc. SPIE, 8644, 86440M (2013).
5. http://www.laserfocusworld.com/articles/print/volume-49/issue-07/features/biomedical-imaging-3d-digital-holograms-visualize-biomedical-applications.html
6. http://www.digitalholography.eu/varasto/05709964.pdf
7. https://www.youtube.com/watch?v=nSEbAJFuoRo

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Global 3D Bioprinting Market: Industry Size, Share and Segments Analysis to 2015 – 2021

Reporter: Irina Robu, PhD

“3D bioprinting is a process of creating spatially-controlled cell patterns in 3D, where viability and cell function are conserved within printed construct. The 3D bioprinting industry that is currently at the embryonic stage of generating replacement human tissue has been forecast to be worth billion dollars by 2019. 3D bioprinting at present largely involves the creation of simple tissue structures in lab settings, but is estimated to be scaled up to involve the creation of complete organs for transplants. This technology is expected to be used for more speedy and accurate drug testing, as potential drug compounds could be tested on bioprinted tissue before human trials commenced.

3D bioprinting is steadily emerging as an area that is gathering attention from a lot of academicians. Some of the researchers have recently opened start-up firms with aim of commercializing the technology in coming years. A number of start-ups have recently sprung up to build up products based on bioprinting. Some are spin outs from university research. The market at present has 14 industry sponsored bioprinters, focused on variety of commercial applications. The widen supply-demand gap for organ transplants is an unmet need; the ultimate goal of researchers is to be able to create bioprinted organs for organ transplants. The focus of this market is expected to shift from research to commercialization. At this stage, the applications such as tissue engineering (skin and cartilage) and drug testing (skin and cartilage) are expected to be popular.

In coming years, 3D bioprinting to be a multi-billion dollar industry owning to early success of bioprinted organ transplants is expected to offer additional boost in subsequent years. The next generation of bioprinters is to offer additional features such as multiple arms and is expected to be comparatively more affordable driving wider adoption. Aspect Biosystems would dramatically cut the cost and time it takes to develop and test the drugs leading to cures for presently incurable diseases and cheaper treatment options. The companies in bioprinting market include SkinPrint that is developing a replacement skin for the burns patients or for those suffering from skin disorders. Aspect Biosystems that is developing printed tissue for drug testing.

Some of the major players for 3D bioprinting market are Advanced Biomatrix, 3D Biotek, 3D Systems, Avita Medical, Bespoke Innovations, Autodesk, EnvisionTEC, Cyfuse Biomedical, CMC Microsystems, Digilab, United Therapeutics, TeVido BioDevices, DTM, Bio3D Technologies, Helisys Inc. CMC Microsystems, InSphero AG and BD Biosciences among others.”

Source

https://www.persistencemarketresearch.com/market-research/3d-bioprinting-market.asp

 

 

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Medical MEMS, Sensors and 3D Printing: Frontier in Process Control of BioMaterials

Curators: Aviva Lev-Ari, PhD, RN and Adam Sonnenberg, BSc

Legal challenges and opportunities for 3D printing

1Executive Summary

As with all paradigm-shifting technologies, the development, adoption, and economic impact of 3D printing will depend not only on technological innovation and market forces but also on the legal considerations that guide those forces. Some, such as law scholar Deven Desai, view 3D printing as a Napster for material science, with the capacity to undermine scarcity — and therefore business models based on material distribution — in the same way that peer-to-peer file sharing has helped to disrupt traditional media industries. Others, such as Adam Rodnitzky, the director of Marketing at 3D scanning manufacturer Occipital, cast doubt on this assessment, comparing 3D printed objects to “a Grateful Dead concert tape that’s been duped a hundred times”: lesser-quality facsimiles that augment rather than diminish the value of scarce originals.

These concerns are only a part of the larger debate surrounding 3D printing, which is forcing legislators and regulators to rethink a broad range of legal issues, from patents to copyrights to liability. Below, we will briefly review a few of these legal issues with the greatest potential to shape the future of this market.

3DXTech Sticks Carbon Nanotubes Into Your 3D Printer’s Feedstock

Michael Molitch-Hou BY ON THU, MAY 8, 2014 · 3D PRINTING,MATERIALS

In March, we covered a company that wants to stick its carbon nanotubes into your 3D printer’s feedstock.  It turns out that they’re not the only ones keen to show you their nanotubes. 3DXTech is a Michigan-based startup that has developed a whole range of filaments for FDM/FFF 3D printing, including one line that’s chock-full of carbon nanotubes for carbon reinforcement.

Pellets for making 3D printing filament

3DXTech has already released a few different standard and speciality filaments for 3D printing.  The first on their list is their iOn™ High-Performance ABS/PA Alloys, which combines ABS with Nylon for the best of both worlds.  The company promises that it prints like ABS, but with better thermal, mechanical, and chemical performance. iOn High Performance ABS/PA Alloys are said to have “higher thermal resistance, superior impact strength, and improved solvent resistance.

carbon nanotube reinforced 3D printing filament3DXNano is the company’s ESD carbon nanotube line.  The carbon nanotube reinforced ABS filament can be used to 3D print components with electrostatic discharge protection, such as parts that may be used for integrated circuits.  Due to the material’s ductility and consistency, as well as increased strength, 3DXNano can be used to 3D print objects for more performance-based applications, such as in the auto, industrial, and semiconductor markets.

And, to accompany all of its filaments, 3DXTech has released its 3DXMax HIPS support material.  This can be used for multi-headed 3D printers to create support structures dissolvable in d-Limonene, for easy clean up.  The HIPS filament is perfect for both the company’s speciality filaments, as well as its standard ABS and PLA filaments.

Finally, if you’ve had a taste of their nanotubes and are eager for more experimentation, you can sign up on their website or like them on Facebook to get access to the materials still in the R&D stages.  They’ve tested these materials to ensure that they print, but have yet to introduce them in full to their online store.  You could be that one, lucky customer to test out an FDM/FFF filament that will change the world of 3D printing forever before anyone else does.

Source: 3DXTech

http://www.3dxtech.com/3dxnano-esd-abs-cnt-3d-printing-filament/

http://3dprintingindustry.com/2014/05/08/3dxtech-sticks-carbon-nanotubes-3d-printers-feedstock/

A Simple, Low-Cost Conductive Composite Material for 3D Printing of Electronic Sensors

Jeongmin Hong, Editor

Abstract

3D printing technology can produce complex objects directly from computer aided digital designs. The technology has traditionally been used by large companies to produce fit and form concept prototypes (‘rapid prototyping’) before production. In recent years however there has been a move to adopt the technology as full-scale manufacturing solution. The advent of low-cost, desktop 3D printers such as the RepRap and emoH@baF has meant a wider user base are now able to have access to desktop manufacturing platforms enabling them to produce highly customised products for personal use and sale. This uptake in usage has been coupled with a demand for printing technology and materials able to print functional elements such as electronic sensors. Here we present formulation of a simple conductive thermoplastic composite we term ‘carbomorph’ and demonstrate how it can be used in an unmodified low-cost 3D printer to print electronic sensors able to sense mechanical flexing and capacitance changes. We show how this capability can be used to produce custom sensing devices and user interface devices along with printed objects with embedded sensing capability. This advance in low-cost 3D printing with offer a new paradigm in the 3D printing field with printed sensors and electronics embedded inside 3D printed objects in a single build process without requiring complex or expensive materials incorporating additives such as carbon nanotubes.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504018/

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049365

MEMS and sensor technologies for medical wearable applications

The medical MEMS and sensor market size is currently approximately $2.4 billion. Medical MEMS and sensors enable applications where it is advantageous to miniaturize components and systems due to form factor, integration and cost considerations. Furthermore, many applications are newly enabled by MEMS and micro-sensor technologies and would not be possible at all without miniaturization.

One of these exciting application segments is medical wearables. While early wearable solutions and prototypes have existed for more than a decade, this segment has been rapidly accelerating its development in the recent past. Enabled by small and cost effective sensors and micro-components, medical wearables are well positioned to be the key driver for enhancing our quality of life while reducing healthcare costs.

We are glad that you were able to join us — by attending this exciting event you will be able to identify emerging technology and application trends, listen to insightful talks, exchange ideas, network with your industry peers, and perhaps even form new companies!

Conference Topics

  • Medical wearables: application trends, business and economic drivers, case studies, challenges, and opportunities.
  • Worldwide healthcare trends: market drivers, demographic factors, government policy effects.
  • Business aspects: fundraising, reimbursement, technology transfer, regulatory compliance, company formation, recruiting, and market research.
  • Digital health: wireless devices, body area networks, online services, genomics, and personal genetic information.
  • Sensors: pressure, thermal, radiation, flow and magnetic sensors used in medical devices as well as implanted systems.
  • Diagnostics: portable assaying and sample preparation of blood, urine, cells, tissues, bodily fluids. For example, microfluidic and lab-on-a-chip devices to diagnose diseases in portable instruments and smaller sized bench top systems.
  • Health screening: preventive medicine such as early detection of cancer through consumer, over-the-counter devices that are to be used on a day-to-day basis.
  • Individualized treatment: integration of diagnostics with therapy and treatment on portable, smart lab-on-a-chip devices; for example, treatment is to be specifically based on the exact disease variation as well as the patient genotype and current health factors.
  • Drug delivery systems: both transdermal and implanted techniques; for example, micro needles that provide convenience and precisely measured amounts of dispensed drugs.  Smart, MEMS based drug delivery systems also enable continual drug delivery monitoring and improve patient compliance.

Sensing technologies for early identification of diabetic foot ulcers
David Goodman, MD, MSE
Co-founder and CEO
FeetFirst

Diabetes is the leading non-traumatic cause of lower extremity amputations in the US. Many people with longstanding diabetes experience nerve damage that results in loss of sensation in the feet, predisposing them to diabetic foot ulcers. These ulcers typically develop insidiously as people at risk have no way to identify the subtle changes that occur in the progression of a foot ulcer until it is obvious and usually advanced to the point that heroic measures (i.e invasive and expensive) are needed to save the foot, if it can be saved at all. Over the years, a variety of non-invasive technologies have been employed in an effort to develop a biomarker that can easily and reliably identify subtle and early changes in the foot that can trigger low cost interventions to prevent a foot ulcer from developing. This talk is focused on a review of these approaches and how they can be incorporated into the digital health ecosystem. Sensing technologies to be highlighted include pressure and thermal mapping as well as hyperspectral, near infrared, colorimetric and visible RGB photographic imaging.

Biography: David is the co-founder and CEO of FeetFirst, a digital health startup that is committed to making diabetic foot ulcers a thing of the past. Starting with co-inventing many of the early innovations in pulse oximetry and then later in remote disease management and now in digital health, David has been fortunate throughout his career to have positively impacted countless people around the world while delivering substantial returns to investors through innovations that he helped to invent. David’s energies are now devoted to combining his expertise in biomedical sensing with the basic building blocks of digital health to create novel and scalable non-invasive biomarkers that enable better health at home as well as in the doctor’s office. David holds a BAS in applied science and bioengineering and a MSE in bioengineering from the University of Pennsylvania. David also received an MD cum laude from Harvard Medical School and the Harvard-MIT Division of Health Sciences and Technology. David completed his internship at the University of California, San Francisco (UCSF) in the Department of Medicine. He holds 18 issued and 4 pending US patents and maintains clinical practices in California and Hawaii.

MEMS technology: key innovation driver for wearable medical devices
Mehran Mehregany, PhD
Director, Case School of Engineering San Diego
Case Western Reserve University

Use of sensor-enabled wearable wireless health solutions to monitor the health condition of chronic disease patients is key to the quality of life of the patient and to reduction of cost of health care – by keeping the patient out of the hospital and emergency rooms. Chronic diseases account for 75%+ of the US health care expenditures. Monitoring for early intervention is key to avoiding long-term adverse outcomes for those at risk of developing chronic diseases. This presentation will elaborate on the important role that MEMS sensors play in enabling wearable, health monitoring solutions. Capturing data is the key to such solutions, which requires sensors of various modalities. MEMS sensors have the advantages of miniaturization, integration and batch fabrication – driving size, performance and cost advantages.

Biography: Mehran Mehregany received his PhD in Electrical Engineering from Massachusetts Institute of Technology in 1990, when he joined Case Western Reserve University. Mehregany founded the Case School of Engineering San Diego in July 2007, and its Wireless Health and Wearable Computing programs in 2011 and 2014, respectively. He is the Director of Case School of Engineering San Diego and Goodrich Professor of Engineering Innovation. Mehregany has over 360 publications describing his work (including a recent textbook on wireless health), holds 20 U.S. patents, is the recipient of a number of awards/honors and has founded several technology startups. His research interests are sensors, micro/nano-electro-mechanical systems, silicon carbide technology and microsystems, wearables and wireless health.

Wearable sensors for greater visibility into dynamic phenotype
David Shaywitz, MD, PhD
Chief Medical Officer
DNAnexus

A key premise of precision medicine, and of the Precision Medicine Initiative, is that the integration of rich genomic and phenotypic information can improve care, inspire science, and drive the development of novel therapeutics. Wearable sensors, a foundational technology of digital health, can provide greater visibility into dynamic phenotype, and complement and dramatically extend the comparatively static and episodic information typically available from the electronic medical record. The increasingly granular assessment of real-world physiology is expected to enable refined patient segmentation, and help define the underlying molecular networks — though this ambition remains largely unrealized. Examples of efforts to integrate clinically-relevant dynamic phenotype with molecular biology in areas such as metabolism and respiratory will be examined. The potential application of other types of sensors, such as those assessing interpersonal interactions and degree of connectivity, will also be reviewed. Potential limitations, as represented by the pulmonary artery catheter experience, will also be discussed.

Biography: Dr. Shaywitz (Twitter: @dshaywitz) is chief medical officer of DNAnexus, a Bay Area company that provides a cloud-based enterprise platform for the management of genomic and other healthcare data. Dr. Shaywitz received his MD/PhD from Harvard and MIT, and trained in internal medicine and endocrinology at MGH. He gained subsequent experience in the Department of Experimental Medicine at Merck, the healthcare practice of the Boston Consulting Group, and at Theravance. He writes extensively about medical innovation, and is co-author, with Lisa Suennen, of “Tech Tonics: Can Passionate Entrepreneurs Heal Healthcare With Technology?” In 2015, they launched “Tech Tonics: The Podcast,” focused on “the people and passions at the intersection of technology and health.” Dr. Shaywitz is a co-founder of the MGH/MIT Center for Assessment Technology and Continuous Health (CATCH) program focused on integrating rich phenotypic assessment with genetic information to guide clinical care and inspire fundamental research.

Wearables for Parkinson’s disease: validating sensors and apps for targeted clinical applications
Joseph Giuffrida, PhD
President and Principal Investigator
Great Lakes NeuroTechnologies

Non-invasive wearable transdermal microsystems for continuous monitoring of bioanalytes
Anand Gadre, PhD
Director, Nanofabrication Research Facility
University of California, Merced

Wearable sensors and big data computing for mobile health: monitoring to interventions
Emre Ertin, PhD
Associate Professor
Ohio State University

SOURCE

Medical MEMS and Sensors 2015 Annual Conference and Exhibition April 29 – 30, 2015 Santa Clara, California

http://medicalmems2015.com/index.html

SPONSORS

Sponsorships for Medical MEMS 2015 are available. For further information and questions about sponsorships, please click here.

Gold Sponsor

Coto Technology, leader in small signal switching solutions, has emerged onto the MEMS scene with its recent release of the RedRock™ RR100 – the world’s smallest MEMS-based magnetic reed sensor. Recognizing the steadily decreasing size requirements of medical devices, and supported by nearly 100 years in relay and switch design technology, Coto Technology is gaining momentum within the realm of MEMS-based switch and relay design. The RR100 sensor offers all of the advantages of conventional magnetic reed sensor technology in a package measuring only 1.11mm3. Ideally suited to the demands of next generation medical applications, the sensor offers directional magnetic sensitivity, ESD resistance, and a robust wafer level package – all while consuming zero power. The RedRock™ RR100 has an increasing number of medical device applications including medical wearables, portable insulin pumps, capsule endoscopes, next generation hearing aids, insulin pens and other small, battery-powered medical electronic devices.

Silver Sponsor

Rogue Valley Microdevices is a full-service precision MEMS foundry that combines state-of-the-art process modules with the engineering expertise to go seamlessly from custom design to manufacturing. Specializing in MEMS and biomedical device manufacturing, Rogue Valley offers a flexible equipment set and smaller batch sizes, playing a critical role in the commercial MEMS manufacturing ecosystem.

At Rogue Valley, we engage in open dialog with our customers, prioritizing your goals and needs every step of the way. We also share engineering-level data with customers, so you can bring up a process at Rogue Valley that you will later use for high-volume production at a larger fab.

Beyond our MEMS fab, Rogue Valley also maintains the broadest and most comprehensive set of wafer services commercially available.

Founded in 2003 and based in Medford, Oregon, Rogue Valley maintains a 200mm MEMS devices foundry. For more information, please visit: www.roguevalleymicro.com.

Program Sponsor

X-FAB is the world’s largest analog/mixed-signal foundry group manufacturing silicon wafers for mixed-signal integrated circuits (ICs). Its marketing network and client base span the Americas, Europe and Asia, offering manufacturing capacity of approximately 744,000 200mm-equivalent wafers per year. The largest specialty fab group, X-FAB is unlike typical foundry services because of its specialized expertise in advanced analog and mixed-signal process technologies.

X-FAB creates a clear alternative to typical foundry services by combining solid, specialized expertise in advanced analog and mixed-signal process technologies with excellent service, a high level of responsiveness and first-class technical support. X-FAB manufactures wafers for automotive, industrial, consumer, medical, and other applications on modular CMOS and BiCMOS processes in geometries ranging from 1.0 to 0.18 µm, and special BCD, SOI and MEMS long-lifetime processes.

Lunch Sponsor

IMT offers the most complete MEMS foundry services in our fully automated 30,000 sq ft, 6” wafer fab.  IMT’s extensive product experience includes DC and RF switching, drug discovery/delivery, microfluidics, cell sorting, inertial navigation, optotelecom, IR emitters, and others.  IMT offers wafer bonding for both hermetic packaging/encapsulation and microfluidics including: fusion bonding, anodic bonding, glass frit bonding, Au-Au thermocompression bonding, metal alloy bonding and various types of polymer bonds.  IMT’s wafer-level packaging and through silicon via technologies are production proven for the next generation 3D packaging and interposer applications.  IMT is ISO 9001 certified offering complete turn-key foundry services from design through high-volume production.  We bring our customers’ MEMS to volume production.  Speak with an IMT representative to see how we can make your MEMS work for you.

Lunch Sponsor

Micralyne is a leading independent MEMS and microfabrication foundry. We excel at creating process technology for complex MEMS devices and execute disciplined volume manufacturing. Micralyne extends its value to our customers by offering extensive packaging, testing, and design services, beyond a typical MEMS chip foundry. This Foundry Plus model has successfully produced products for industries such as: life sciences, aerospace, automotive, oil and gas, telecom, and industrial sensors. Micralyne offers our customers a strategic partnership with deep technical knowledge and fabrication capabilities. Our fabrication services fit their need by providing established process platforms and timely device fabrication through early prototype, qualification, and volume manufacturing.

Breakfast Sponsor

Meeting the stringent demands of companies worldwide, Yield Engineering Systems, Inc. (YES) manufactures equipment with cost-effective solutions for wafer-level packaging/redistribution layers, bioMEMS, semiconductor industries and more. We manufacture high temperature vacuum cure ovens, polyimide cure ovens, silane vapor phase deposition systems, plasma etch and clean tools and vacuum bake/vapor prime ovens. Proven applications using these systems include silane substrate adhesion for microarrays, biocompatibility, stiction reduction, wafer dehydration and surface tension modification. YES has proven to withstand the test of time with products that increase yields, extend performance, and improve processes. All equipment is engineered, manufactured and tested in Livermore, California USA. The answer is YES to quality, flexibility, superior products and service. Visit us during the show at Booth #9.

Breakfast Sponsor

The ASE Group is the world’s largest provider of independent semiconductor manufacturing services in assembly and test. The group develops and offers complete turnkey solutions covering IC packaging, design and production of interconnect materials, front-end engineering test, wafer probing and final test, as well as electronic manufacturing services through Universal Scientific Industrial Co Ltd. As global leader, ASE provides a complete scope of services for the semiconductor market, driven by superior technologies, breakthrough innovations, and advanced development programs.

Association Sponsor

The MEMS and Nanotechnology Exchange (MNX) has been providing services to the U.S. research community since 1999. We have completed over 2300 unique development and fabrication projects for our customers. We have thousands of MEMS and Nano process technologies available in our advanced processing facility, along with technical assistance from experienced and talented fabrication and process development engineers. MNX can provide a complete range of services to researchers who need a trusted partner at any project phase, including early-stage development, design and modeling, prototype fabrication, or transition to manufacturing. Contact us atwww.mems-exchange.org to ask how we can help you quickly and affordably transform your concept from prototype to production!

SOURCE

http://medicalmems2015.com/sponsors.html

Many thanks to our exhibitors from the 2013 event.

http://www.acam.de/products/picocap/applications/mems

acam provides intelligent ASIC solutions for MEMS sensors. The versatile solutions can be used with a variety of sensors (e.g. capacitive or resistive) and are well suited for portable medical devices thanks to the very low current consumption. The high resolution and measurement rate of the chips make them perfect for the use in high-end applications. The on-board processing capability in form of a microprocessor allows for compact sensor fusion, e.g. to make the linearization of a pressure sensor directly on chip.

acam is a privately owned company with its headquarter located in the south of Germany. A worldwide distributor network assures local support with offices in North America, Europe and Asia.

http://www.alphaprecision.com

Alpha Precision specializes in custom ultrasonic machining of wafers and high precision surface polishing for excellent anodic bonding for MEMS. The ultrasonic process results in high precision placement and tolerances of features on the MEMS wafer. Ultrasonic machining does not impart any substrate cracking, stress or temperature change. This process is applicable to many different brittle substrates such as glass and ceramic. End use features include through vias, cavities and grooves. ISO/TS 16949:2009 Certified Quality Process.

Alpha Precision also does specialty MicroBlast machining of many different shapes and sizes.

http://www.boschman.nl

Boschman Technologies is the world leading supplier of automatic molding systems that use film for the encapsulation of Sensor and MEMS devices. This process, called Film Assisted Molding is ideal for applications where sensing surfaces or bond pads or heat sinks must be exposed and free of mold compound bleed and flash. This technology is used for MEMS, Sensor, Solar, and Optical molding applications with the transfer molding of epoxy or silicone based mold compounds, including clear materials. In addition, Boschman serves as a one-stop shop for research, development, qualification, prototyping and small volume manufacturing services by focusing on MEMS, Sensors, and advanced IC and wafer level packaging applications. By working closely with customer R&D departments to explore new packaging concepts, value from Innovation to Industrialization is provided.

http://www.finetechusa.com

Finetech’s precision die bonders provide sub-micron placement accuracy and process modularity within one platform: thermo-compression/sonic, eutectic, epoxy, ACF & Indium bonding, sensitive materials (GaAs/GaP), UV curing. Ideal solutions for advanced technology applications: flip chip, laser bars & diodes, VCSELs, MEMs, sensors, detectors, 3D, W2W / C2W, photonics packaging, and micro-optics assembly.

http://www.ggba-switzerland.ch

The Greater Geneva Berne area is a Swiss economic development agency representing the interest of six Swiss cantons (states) in Western Switzerland: Berne, Fribourg, Geneva, Neuchatel, Valais and Vaud. Surrounded by France, Germany and Italy, our region offers a welcoming environment for companies to collaborate, develop and commercialize their technologies on an international scale. With our dense and sophisticated life science and microtechnology clusters representing nearly 5000 companies, more than 500 labs, and 120,000 workers, these sectors have converged to create an academic and commercial environment of international renown in the MEMS, sensors, and high-tech biomedical sectors.

Companies are drawn to our region because of the potential for synergies and close collaboration with our unique institutions such as the Swiss Federal Institute of Technology (EPFL) with 19 specialized labs in microtechnology, the Swiss Center for Electronics and Microtechnology (CSEM), the Swiss Foundation for Research in Microtechnology, our six cantonal universities, and our three University Hospitals of Berne, Geneva, and Lausanne.

Research is a top priority in Switzerland where more scientific publications and patents are filed per capita than anywhere else in the world. Our region’s above average spending on fundamental and applied research is the result of long-standing policies and initiatives to attract investment and collaboration in high value-added sectors.

We offer an accessible regulatory environment; an open clinical community; low taxes; an educated, multilingual, multicultural workforce; science parks and incubators; networking platforms; state-funded collaboration programs; and a world-class quality of life.

As a government sponsored association, our mission is to provide support and assistance to companies (MEMS, sensors, life sciences, etc.) interested in the benefits that Switzerland can bring to them. Our support ranges from facilitating relationships with potential partners to helping negotiate the regulatory environment to all aspects of establishing an enterprise in Switzerland. For more information, please contact Matt Julian at 512-301-3337 (office), 512-586-7035 (cell) or m.julian@ggba-switzerland.ch (email).

http://www.himt.de/en/home

Founded in 1984, Heidelberg Instruments is today a global leader in design, development and manufacturing of complex laser based maskless lithography systems. These systems are critical to fabrication of advanced photomasks and direct write solutions in the areas of Advanced Electronic Packaging, Flat Panel Display, MEMS, Integrated Optics and other micro and nano based applications.

Heidelberg Instruments’ customers include many of the major global nano and micro technology based corporations along with some of the leading research and development organizations that provide components used in an array of electronic, communication and information technology products.

Heidelberg Instruments is located in Heidelberg, Germany, with global customer support offices in Asia, Europe, and North America. The company is 100% privately owned by the management and employees.

http://www.kent.edu

Kent State University is internationally recognized for its biomedical research. Current research strengths across the many disciplines at Kent State are particularly compatible with the bioengineering fields of tissue regeneration, biomaterials, biocompatibility, sensors and implanted devices. Our researchers are developing transdermal implants for amputees, improving neural function with implanted electrodes, creating implanted sensors for monitoring blood chemistry and vital signs and designing drug delivery devices that can be implanted or worn on the skin. Our researchers are also developing new medical sensors using advanced organic and polymeric materials to measure biomarkers and other biochemical indicators of disease, injury and trauma. Other materials research focuses on improving the biocompatibility of materials, decreasing the risk of infection from implanted devices, producing Lab-on-a-Chip devices for diagnostic and therapeutic applications and creating a new generation of flexible electronic medical devices for implantation and other applications. Kent State is also known for its research strengths in flexible electronics and liquid crystals within its Liquid Crystal Institute™(LCI).

http://www.nordson.com

Nordson Corporation operates in more than 30 countries around the world delivering precision technology solutions to help customers succeed worldwide. The company engineers, manufactures and markets differentiated products and systems used for dispensing adhesives, coatings, sealants, biomaterials and other materials, fluid management, test and inspection, UV curing and plasma surface treatment, all supported by application expertise and direct global sales and service. Nordson serves a wide variety of consumer non-durable, durable and technology end markets including packaging, nonwovens, electronics, medical, appliances, energy, transportation, construction, and general product assembly and finishing.

http://www.lnf.umich.edu

The National Nanotechnology Infrastructure Network (NNIN) is an integrated network of user facilities, supported by the National Science Foundation, serving the needs of nanoscale science, engineering and technology researchers across the country. The goal of the NNIN is to enable rapid advancement in science and engineering at the nanoscale by providing researchers with efficient access to nanotechnology infrastructure (fabrication, characterization and computational capabilities and facilities) and support from experienced staff members.

The Lurie Nanofabrication Facility (LNF) at the University of Michigan is one of the NNIN sites that offers 24/7 semiconductor processing capabilities on production-level equipment supported by a professional staff. With 1,160 m2 (12,500 ft2) of ISO class 4/5/6 and 7 (Class 10/100/1000 and 10,000) cleanrooms for processing pieces, 100 mm and 150 mm wafers, we have processing capabilities for silicon and organic devices, MEMs and bioMEMs, fluidics and biofluidics, and nanoimprint technologies.

With such an available suite of established technologies for a large range of applications, the LNF is ideal for rapid feasibility assessment of ideas and pilot/low-volume products. Whether you want to assess new process adjustments for your product without compromising your current process, explore new device directions, or simply take advantage of our advanced characterization capabilities, the LNF provides the complete cleanroom experience for your high tech needs. The LNF is also part of the National Nanotechnology Infrastructure Network (NNIN), an integrated network of user.

With over $20M in state-of-the-art equipment, we provide the training and experience that will turn your ideas into reality. A full list of available equipment and capabilities are available online athttp://lnf.umich.edu/index.php/capabilities.

Original Biomedical Implants, Inc. (OBI) was established in Texas with an initial focus of commercializing a new generation of dental drills and implants with a unique patented ultrananocrystalline diamond (UNCD) coating, which enables an order of magnitude superior performance over current products at competitive costs. After a return on investment (3 years), OBI will also commercialize high-revenue new generation medical devices such as MEMS drug delivery devices and biosensors, UNCD-coated prosthesis (e.g., hips, knees, stents), electrically conductive UNCD electrodes for neural stimulation, and much more. UNCD-based products will address the global health business which is projected to reach $365 billion per year in 2015 (Global Industry Analyst, February 2012).

http://rbbsystems.com

The Premiere Electronics Job Shop

At RBB Systems, we specialize in on-demand manufacturing of mission-critical electronic assemblies for the industrial, commercial, medical and military sectors. By embracing small batch custom assemblies of electronic circuit boards, we allow clients greater flexibility in meeting fluctuating market demands.

We combine the best lean manufacturing principles with a hungry can-do attitude. Our cost-effective, team-driven approach offers a meaningful alternative to offshore production. Our organizational mission is simple: We exist to move heaven and earth to get our small batch customers what they need, when they need it.

If you need low-volume printed circuit board assembly to support second-tier product lines or other small batch industrial electronics work, we invite you to contact us to learn more about our services, philosophies and capabilities.

http://www.roguevalleymicro.com

Specializing in MEMS and biomedical device fabrication, Rogue Valley Microdevices is a full service MEMS foundry that combines state-of-the-art process modules with the engineering experience and expertise to seamlessly go from custom design to device manufacturing. With our extensive list of process capabilities, all front-end processing is performed in house. Maintaining all MEMS process capabilities in house enables us to decrease manufacturing lead-times while improving device yield and performance.

Rogue Valley Microdevices offers over 50 unique MEMS manufacturing and thin film processes to support our worldwide customer base. Our MEMS and thin film processes are designed to handle silicon wafer substrates, as well as a variety of other material such as quartz, glass and aluminum nitride wafers. Our goal is to minimize process development time, keeping your cost and lead-time to a minimum. We have extensive MEMS manufacturing experience and understand how important it is to have a robust and repeatable process.

Rogue Valley Microdevices is based in beautiful Southern Oregon. We supply services to customers with a wide variety of applications, including those in MEMS, semiconductors, biotechnology and nanotechnology. To contact us, please go to: http://www.roguevalleymicro.com/contact.php.

http://www.semefab.com

Semefab is a volume foundry supporting an extensive process portfolio of MEMS, MOS, bipolar, opto-CMOS, ASIC and discrete technologies and supplies silicon wafers, die and packaged devices to the market. Semefab operates its own 6-inch and 4-inch volume foundries with complete autonomy between its MEMS and MOS/bipolar fabs.

Semefab also supports wafer and package test in its facilities. Supporting a commercialization business model, Semefab optimizes device structures and process flows within an ISO accredited environment and seamlessly transfers these into its volume foundries. As a global foundry, Semefab exports more than 74% of its fabricated product and ships more than 200 million die per year.

http://www.tecnisco.co.jp/en

TECNISCO, LTD. is a subsidiary of Disco Corporation, a worldwide manufacturer of dicing saws and grinding machines. They supply customized parts that are manufactured with Glass, Metal, Ceramic, or Silicon by its advanced high-precision processes and composite technologies for the MEMS industry. Tecnisco’s expertise includes: dicing, ultrasonic machining, sandblasting, milling (drilling), assembling (AuSn, AuGe, AgCuIn, AgCu), polishing, bonding, plating, sputtering, vapor deposition and more. Their target is to be a best solution partner from trial production to mass production.

http://www.tousimis.com

Tousimis manufactures highly reliable Supercritical CO2 Dryers. Our Critical Point Dryer (CPD) process technology eliminates surface tension forces enabling delicate 3-D micro structure preservation.

Current CPD applications include Biological, MEMS, Bio-MEMS, Aero Gel, Nano Particle, Carbon Nanotube, Graphene and others.

Tousimis also manufactures high purity fixatives and X-Ray Reference standards.

Tousimis is a USA based company supported via a global sales and service network.

http://www.uakron.edu/engineering/BME

Biomedical Engineering at The University of Akron is both patient-centered as well as student-focused. We seek to find solutions to pressing needs of the medical community, and we expect our students to be at the forefront of medical innovation. Within our department, we focus on three areas of specialization: Biomechanics, Biomaterials & Tissue Engineering, and Instrumentation, Signals & Imaging. Through these areas we strive to (i) better understand mechanisms of disease, (ii) develop improved technologies for diagnosing or treating diseases, and (iii) educate the next generation of biomedical engineers. Knowledge gained through this approach fuels the rapid expansion of our region’s biomedical sector.

SOURCE

http://www.medicalmems2014.com/exhibitors.html

How light could play a role in tissue engineering

http://www.photonics.com/VideoGallery.aspx?DCID=c83b7944ee4e4e7da95582d788f16210

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Scientists have managed to build a fully functional neuron by using organic bioelectronics

Reporter: Aviva Lev-Ari, PhD, RN

 

Scientists at Karolinska Institutet have managed to build a fully functional neuron by using organic bioelectronics. This artificial neuron contain no ‘living’ parts, but is capable of mimicking the function of a human nerve cell and communicate in the same way as our own neurons do.

 

Neurons are isolated from each other and communicate with the help of chemical signals, commonly called neurotransmitters or signal substances. Inside a neuron, these chemical signals are converted to an electrical action potential, which travels along the axon of  the neuron until it reaches the end. Here at the synapse, the electrical signal is converted to the release of chemical signals, which via diffusion can relay the signal to the next nerve cell.

 

To date, the primary technique for neuronal stimulation in human cells is based on electrical stimulation. However, scientists at the Swedish Medical Nanoscience Centre (SMNC) at Karolinska Institutet’s Department of Neuroscience in collaboration with collegues at Linköping University, have now created an organic bioelectronic device that is capable of receiving chemical signals, which it can then relay to human cells.

 

“Our artificial neuron is made of conductive polymers and it functions like a human neuron”, says lead investigator Agneta Richter-Dahlfors, professor of cellular microbiology. “The sensing component of the artificial neuron senses a change in chemical signals in one dish, and translates this into an electrical signal. This electrical signal is next translated into the release of the neurotransmitter acetylcholine in a second dish, whose effect on living human cells can be monitored.“

Sourced through Scoop.it from: ki.se

See on Scoop.itCardiovascular and vascular imaging

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‘No-Ink’ color printing with nanomaterials that is only visible with high-powered electron microscopy

Reporter: Aviva Lev-Ari, PhD, RN

Researchers at Missouri University of Science and Technology are giving new meaning to the term ‘read the fine print’ with their demonstration of a color printing process using nanomaterials.

 

this case, the print features are very fine – visible only with the aid of a high-powered electron microscope. The researchers describe their “no-ink” printing method in the latest issue of the Nature Publishing Group journal Scientific Reports and illustrate their technique by reproducing the Missouri S&T athletic logo on a nanometer-scale surface. A nanometer is one billionth of a meter, and some nanomaterials are only a few atoms in size.

 

The method described in the Scientific Reports article “Structural color printing based on plasmonic metasurfaces of perfect light absorption” involves the use of thin sandwiches of nanometer-scale metal-dielectric materials known as metamaterials that interact with light in ways not seen in nature. Experimenting with the interplay of white light on sandwich-like structures, or plasmonic interfaces, the researchers developed what they call “a simple but efficient structural color printing platform” at the nanometer-scale level. They believe the process holds promise for future applications, including nanoscale visual arts, security marking and information storage.

 

The researchers’ printing surface consists of a sandwich-like structure made up of two thin films of silver separated by a “spacer” film of silica. The top layer of silver film is 25 nanometers thick and is punctured with tiny holes created by a microfabrication process known as focused ion beam milling. The bottom layer of silver is four times thicker than the top layer but still minuscule at 100 nanometers. Between the top and bottom films lies a 45-nanometer silica dielectric spacer.

 

The researchers created a scaled-down template of the athletic logo and drilled out tiny perforations on the top layer of the metamaterial structure. Under a scanning electron microscope, the template looks like a needlepoint pattern of the logo. The researchers then beamed light through the holes to create the logo using no ink – only the interaction of the materials and light.

 

By adjusting the hole size of the top layer, light at the desired frequency was beamed into the material with a perfect absorption. This allowed researchers to create different colors in the reflected light and thereby accurately reproduce the S&T athletic logo with nanoscale color palettes. The researchers further adjusted the holes to alter the logo’s official green and gold color scheme to introduce four new colors (an orange ampersand, magenta “S” and “T,” cyan pickaxe symbol and navy blue “Missouri”).

Sourced through Scoop.it from: phys.org

See on Scoop.itCardiovascular and vascular imaging

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New device to store electricity on silicon chips themselves

Reporter: Aviva Lev-Ari, PhD, RN

 

See on Scoop.itCardiovascular and vascular imaging

All the things that define us in a modern environment require electricity,” said Pint. “The more that we can integrate power storage into existing materials and devices, the more compact and efficient they will become.” New device stores electricity on silicon chips.

 

Solar cells that produce electricity 24/7, not just when the sun is shining. Mobile phones with built-in power cells that recharge in seconds and work for weeks between charges. These are just two of the possibilities raised by a novel supercapacitor design invented by material scientists at Vanderbilt University that is described in a paper published in the Oct. 22, 2013 issue of the journal Scientific Reports.

 

It is the first supercapacitor that is made out of silicon so it can be built into a silicon chip along with the microelectronic circuitry that it powers. In fact, it should be possible to construct these power cells out of the excess silicon that exists in the current generation of solar cells, sensors, mobile phones and a variety of other electromechanical devices, providing a considerable cost savings.

 

“If you ask experts about making a supercapacitor out of silicon, they will tell you it is a crazy idea,” said Cary Pint, the assistant professor of mechanical engineering who headed the development. “But we’ve found an easy way to do it.”

 

Instead of storing energy in chemical reactions the way batteries do, “supercaps” store electricity by assembling ions on the surface of a porous material. As a result, they tend to charge and discharge in minutes, instead of hours, and operate for a few million cycles, instead of a few thousand cycles like batteries.

 

“The big challenge for this approach is assembling the materials,” said Pint. “Constructing high-performance, functional devices out of nanoscale building blocks with any level of control has proven to be quite challenging, and when it is achieved it is difficult to repeat.”

 

With experience in growing carbon nanostructures, Pint’s group decided to try to coat the porous silicon surface with carbon. “We had no idea what would happen,” said Pint. “Typically, researchers grow graphene from silicon-carbide materials at temperatures in excess of 1400 degrees Celsius. But at lower temperatures – 600 to 700 degrees Celsius – we certainly didn’t expect graphene-like material growth.”

 

 

When the researchers pulled the porous silicon out of the furnace, they found that it had turned from orange to purple or black. When they inspected it under a powerful scanning electron microscope they found that it looked nearly identical to the original material but it was coated by a layer of graphene a few nanometers thick.

 

 

When the researchers tested the coated material they found that it had chemically stabilized the silicon surface. When they used it to make supercapacitors, they found that the graphene coating improved energy densities by over two orders of magnitude compared to those made from uncoated porous silicon and significantly better than commercial supercapacitors.

 

See on news.vanderbilt.edu

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Graphene Becomes Magnetic for First Time

Reporter: Aviva Lev-Ari, PhD, RN

 

See on Scoop.itAmazing Science

Researchers from both the University of Madrid Complutense and the Universidad Autonoma working together at the IMDEA-Nanociencia Institute in Spain have for the first time given graphene magnetic properties, opening up the potential that the material can find new applications in future spintronic devices. Unlike electronics in which an electron’s charge-carrying capabilities are exploited to create circuits, spintronics involves the quantum mechanical property of electrons to spin, which creates a magnetic moment that makes the electrons behave briefly like magnets. When in the presence of a magnetic field the spin of the electrons moves either into a parallel or antiparallel position in relation to the field. This positioning can be translated into a binary signal.

 

The trials and tribulations trying to make graphene applicable to electronics despite its lack of an inherent band gap have been well documented. However, what many have overlooked in the quest to bring graphene to electronics is that it doesn’t really lend itself very well to spintronics either. Since 2007, researchers have looked at graphene as the material for channels in spintronic devices. At this function, it appears to excel. In fact, just this year record distances were achieved for carry information using the spin of electrons.

 

Unfortunately, when two-dimensional graphene is laid out flat, the motion of electrons moving through the material doesn’t influence the spin of other electrons that they pass. Instead the direction and the spin of electrons remain random rather than patterned. More than two years ago, researchers at the University of Copenhagen discovered that that all changed if you curved the graphene into a cylinder. In that shape, the movement of electrons did influence the spin of other electrons, opening the door to their potential in spintronics.

 

In order for a material to be have magnetic properties a majority of the electrons in the material must be spinning in the same direction. Despite the work of the Copenhagen researchers and many others, it has remained a challenge to get graphenes’ electrons to spin in the same direction instead of just randomly. But the Spanish researchers believe they have accomplished it.

 

“In spite of the huge efforts to date of scientists all over the world, it has not been possible to add the magnetic properties required to develop graphene-based spintronics. However these results pave the way to this possibility,” says Prof. Rodolfo Miranda, Director of IMDEA-Nanociencia, in a press release.

 

The research, which was published in the journal Nature Physics (“Long-range magnetic order in a purely organic 2D layer adsorbed on epitaxial graphene”), first grew ultra pure graphene film over a crystal inside of a vacuum. While still in the vacumm, the researchers evaporated molecules of a semiconductor on the graphene’s surface. When they observed the material with a scanning tunneling microscope, they were surprised to discover that the semiconductor molecules were organized and regularly distributed across the surface of the graphene and its crystal substrate.

 

Since spintronics hasn’t really progressed beyond its application into devices beyond hard-disk drives, the ability to give graphene magnetic properties likely won’t bring spintronic devices into other applications any sooner. But these kinds of breakthroughs do have a way of opening up unexpected possibilities.

See on spectrum.ieee.org

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