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Archive for the ‘Cardiovascular Research’ Category

Hypertension | Adam Multimedia Encyclopedia | Maimonides Medical Center – www.MMCBrooklyn.org

Posted in Cardiovascular Research, HTN, Origins of Cardiovascular Disease, Pharmacotherapy of Cardiovascular Disease, Uncategorized on February 21, 2016| Leave a Comment »

Signs and tests Your health care provider will perform a physical exam and check your blood pressure. If the measurement is high, your health care provider may think you have high blood pressure.

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Ngai-Yin Chan-The Practice of Catheter Cryoablation for Cardiac Arrhythmias[PDF]

Posted in Cardiac & Vascular Repair Tools Subsegment, Cardiovascular Research, Clinical Diagnostics, Electrophysiology, Frontiers in Cardiology and Cardiovascular Disorders, Heart Failure (HF), Medical Devices R&D and Inventions, Pharmacotherapy of Cardiovascular Disease, Stents & Tools, Technology Advance Assessment of, Uncategorized on February 21, 2016| Leave a Comment »

Ngai-Yin Chan-The Practice of Catheter Cryoablation for Cardiac Arrhythmias[PDF] 20 MB PDF… https://t.co/8EYkq36tJA

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Antihypertensive Drugs

Posted in Cardiovascular Research, Frontiers in Cardiology and Cardiovascular Disorders, Heart Failure (HF), HTN, Pharmacotherapy of Cardiovascular Disease on February 21, 2016| Leave a Comment »

Antihypertensive Drugs

Reporter: Aviva Lev-Ari, PhD, RN

 

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An animated video on Mechanism of action of antihypertensive drugs for Ty and Final Year students. And also for those preparing for competitive exams.

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A case of ischemic cardiomyopathy. ECG, echo, SPECT, coronary angiography and treatment.

Posted in Acute Myocardial Infarction, Cardiomyopathy, Frontiers in Cardiology and Cardiovascular Disorders, Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on February 21, 2016| Leave a Comment »

A case of ischemic cardiomyopathy. ECG, echo, SPECT, coronary angiography and treatment.

Reporter: Aviva Lev-Ari, PhD, RN

 

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A case of heart failure due to ischemic cardiomyopathy in the context of a previous myocardial infarction. The ECG, the echocardiogram, the myocardial perfus…

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Remote Ischemic Preconditioning for Heart Surgery

Posted in Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on February 21, 2016| Leave a Comment »

Remote Ischemic Preconditioning for Heart Surgery

Reporter: Aviva Lev-Ari, PhD, RN

 

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Remote ischemic preconditioning has been reported to reduce biomarkers of ischemia and reperfusion injury in patients who undergo cardiac surgery. But does i…

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CMR as a Prognostic Tool in Ischemic Heart Disease: Part 1

Posted in Acute Myocardial Infarction, Frontiers in Cardiology and Cardiovascular Disorders, Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on February 17, 2016| Leave a Comment »

CMR as a Prognostic Tool in Ischemic Heart Disease: Part 1

Reporter: Aviva Lev-Ari, PhD, RN

 

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This presentation starts with the basics of late gadolinium enhancement, then moves to what CMR tells us about the recovery from acute myocardial infarction….

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Ischemia – definition, symptoms & pathophysiology

Posted in Cardiovascular Research, Frontiers in Cardiology and Cardiovascular Disorders, Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on February 17, 2016| Leave a Comment »

Ischemia – definition, symptoms & pathophysiology

Reporter: Aviva Lev-Ari, PhD, RN

 

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What is ischemia? When cells don’t receive enough oxygen, they can become ischemic, and ultimately die, leading to tissue necrosis. This video covers the pat…

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Epicardial adipose tissue volume but not density is an independent predictor for myocardial ischemia. – PubMed – NCBI

Posted in Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on February 17, 2016| Leave a Comment »

Epicardial adipose tissue volume but not density is an independent predictor for myocardial ischemia. – PubMed – NCBI

Reporter: Aviva Lev-Ari, PhD, RN

 

J Cardiovasc Comput Tomogr. 2016 Jan 13. pii: S1934-5925(16)30008-9. doi: 10.1016/j.jcct.2016.01.009.

[Epub ahead of print]

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Heart-Failure–Related Mortality Rate: CDC Reports comparison of 2000, 2012, 2014 – the decease is steadily reversed

Posted in Cardiovascular Research, congestive heart failure, Frontiers in Cardiology and Cardiovascular Disorders, Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism, Origins of Cardiovascular Disease, tagged on January 5, 2016| Leave a Comment »

Heart-Failure–Related Mortality Rate: CDC Reports comparison of 2000, 2012, 2014  – the decease is steadily reversed

Reporter: Aviva Lev-Ari, PhD, RN

 

The report, which examined heart-failure trends between 2000 and 2014, showed that the age-adjusted rate for HF-related mortality was 105.4 per 100,000 population in 2000 and only 81.4 per 100,000 in 2012 (P<0.05). However, the rate then started a slow but steady climb, reaching 84.0 per 100,000 in 2014.

Not so surprising: men of all ages still had a higher death rate vs women in 2014, and black individuals had a higher rate than whites (91.5 vs 87.3 deaths per 100,000) and Hispanics (53.3 per 100,000).

 

CDC: Heart-Failure–Related Mortality Rate Climbs After Decade-Long Decrease

Deborah Brauser

January 04, 2016

http://www.medscape.com/viewarticle/856704?nlid=95763_3866&src=wnl_edit_medp_card&uac=93761AJ&spon=2&impID=944924&faf=1

NCHS Data Brief

Number 231, December 2015

Recent Trends in Heart Failure-related Mortality: United States, 2000–2014

PDF Version Adobe PDF file (351 KB)

Hanyu Ni, Ph.D.; and Jiaquan Xu, M.D.

 

Key findings

Data from the National Vital Statistics System, Mortality

  • The age-adjusted rate for heart failure-related deaths decreased from 2000 through 2012 but increased from 2012 through 2014.
  • The death rate for heart failure was higher for the
    non-Hispanic black population than for the non-Hispanic white and Hispanic populations.
  • The death rate was higher for men than for women in all age groups. The gap in the death rate for adults aged 45–64 and 85 and over increased over time.
  • The percentage of heart failure-related deaths that occurred in a hospital decreased from 2000 through 2014.
  • The percentage of heart failure-related deaths for adults aged 45 and over with coronary heart disease as the underlying cause of death decreased 32%, from 34.9% in 2000 to 23.9% in 2014.

Heart failure is a major public health problem associated with significant hospital admission rates, mortality, and costly health care expenditures, despite advances in the treatment and management of heart failure and heart failure-related risk factors (1–4). Using data from the multiple cause of death files, this report describes the trends in heart failure-related mortality from 2000 through 2014 for the U.S. population, by age, sex, race and Hispanic origin, and place of death. Heart failure-related deaths were identified as those with heart failure reported anywhere on the death certificate, either as an underlying or contributing cause of death. Changes in the underlying causes of heart failure-related deaths are also described in this report.

Keywords: mortality, heart failure, trend, National Vital Statistics System

SOURCE

http://www.cdc.gov/nchs/data/databriefs/db231.htm

 

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Beta-blocker use in ST-segment elevation myocardial infarction in the reperfusion era (GRACE). – PubMed – NCBI

Posted in Acute Myocardial Infarction, Atrial Fibrilation (a-Fib), Cardiac Pacing and Arrhythmias, Cardiac and Cardiovascular Surgical Procedures, Frontiers in Cardiology and Cardiovascular Disorders, Myocardial metabolism, Myocardial ischemia, myocardial perfusion, Myocardial adenine nucleotide metabolism on December 26, 2015| Leave a Comment »

 

Beta-blocker use in ST-segment elevation myocardial infarction in the reperfusion era (GRACE). – PubMed – NCBI

Reporter: Aviva Lev-Ari, PhD, RN

 

Am J Med. 2014 Jun;127(6):503-11. doi: 10.1016/j.amjmed.2014.02.009. Epub 2014 Feb 18. Multicenter Study; Observational Study; Research Support, Non-U.S. Gov’t

Beta-blocker use in ST-segment elevation myocardial infarction in the reperfusion era (GRACE)

Kay Lee Park1, Robert J Goldberg1, Frederick A Anderson1, José López-Sendón2, Gilles Montalescot3, David Brieger4, Kim A Eagle5, Allison Wyman1, Joel M Gore6, Global Registry of Acute Coronary Events Investigators
Affiliations 

Abstract

Background: Current guidelines recommend early oral beta-blocker administration in the management of acute coronary syndromes for patients who are not at high risk of complications.

Methods: Data from patients enrolled between 2000 and 2007 in the Global Registry of Acute Coronary Events (GRACE) were used to evaluate hospital outcomes in 3 cohorts of patients admitted with ST-elevation myocardial infarction, based on beta-blocker use (early [first 24 hours] intravenous (IV) [± oral], only early oral, or delayed [after first 24 hours]).

Results: Among 13,110 patients with ST-elevation myocardial infarction, 21% received any early IV beta-blockers, 65% received only early oral beta-blockers, and 14% received delayed (>24 hours) beta-blockers. Higher systolic blood pressure, higher heart rate, and chronic beta-blocker use were independent predictors of early beta-blocker use. Early beta-blocker use was less likely in older patients, patients with moderate to severe left ventricular dysfunction, and in those presenting with inferior myocardial infarction or Killip class II or III heart failure. IV beta-blocker use and delayed beta-blocker use were associated with higher rates of cardiogenic shock, sustained ventricular fibrillation/ventricular tachycardia, and acute heart failure, compared with oral beta-blocker use. In-hospital mortality was increased with IV beta-blocker use (propensity score adjusted odds ratio, 1.41; 95% confidence interval, 1.03-1.92) but significantly reduced with delayed beta-blocker administration (propensity adjusted odds ratio, 0.44; 95% confidence interval, 0.26-0.74).

Conclusions: Early beta-blocker use is common in patients presenting with ST-elevation myocardial infarction, with oral administration being the most prevalent. Oral beta-blockers were associated with a decrease in the risk of cardiogenic shock, ventricular arrhythmias, and acute heart failure. However, the early receipt of any form of beta-blockers was associated with an increase in hospital mortality.

Keywords: Clinical outcomes; Intravenous beta-blockers; Oral beta-blockers; ST-elevation myocardial infarction.

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