Original Tweets Re-Tweets and Likes by @pharma_BI and @AVIVA1950 at #kisymposium for 17th annual Summer Symposium: Breakthrough Cancer Nanotechnologies: Koch Institute, MIT Kresge Auditorium, June 15, 2018, 9AM-4PM
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Aviva Lev-Ari @AVIVA1950
2.1.3.6 Original Tweets Re-Tweets and Likes by @pharma_BI and @AVIVA1950 at #kisymposium for 17th annual Summer Symposium: Breakthrough Cancer Nanotechnologies: Koch Institute, MIT Kresge Auditorium, June 15, 2018, 9AM-4PM, Volume 2 (Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS and BioInformatics, Simulations and the Genome Ontology), Part 2: CRISPR for Gene Editing and DNA RepairMoreAviva Lev-Ari Retweeted Anne E Deconinck
Enjoyed his comment on the Panel
#KISymposiumAviva Lev-Ari added,
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SG: molecular micro bubbles for molecular targeting to understand human cancer
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SG: First micro bubble targeting KDR for human cancer detection to assess clinical safety in breast and ovarian lesions and feasibility to detect via ultrasound. Molecular imaging to histology
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SG: dosing up to 0.08 ml/kg well tolerated, well tolerated, 40 subjects, defining malignant and benign disease
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SG: important signal imaging differentiating cancer lesions
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Ralph Weissleder (Harvard): the three pillars of cancer diagnostics
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Aviva Lev-Ari Retweeted Patrice Milos
two technologies will lead the way
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AB: amazing to see data on using the M13 phage with carbon nanotube homing to tumors prior to surgery allowing localization of tumors <1mm in size!
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Aviva Lev-Ari Retweeted Patrice Milos
Great technology emerging
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Aviva Lev-Ari Retweeted Anne E Deconinck
Enjoyed the talk very much
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AB: Great props to present her virus and strategies for genetically engineering virus to bind to carbon nanotubes!
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Suzie Pun (Univ of Washington): targeting tumor associated macrophage as way to potentiate targeted therapies
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Aviva Lev-Ari Retweeted Julien C. Senécal
cutting edge
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Daniel Anderson (Koch): Can nanoparticles be used for delivery of Genome editing tools? Inside cells?
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Aviva Lev-Ari Retweeted Anne E Deconinck
Great visualization in Angie Belcher’s presentation
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DA: wow, fascinating delivery of gene editing machinery to liver or lungs to correct gene defects, AAV for sgRNA and repair DNA plus nanoparticle containing Cas9 mRNA – and it worked in animal model to correct metabolic defect.
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Sangeeta Bhatia stresses the importance of
#nano for early detection of#cancer especially in low-resource setting. Also promoting the launch of#MITnano this year#KIsymposium -
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Aviva Lev-Ari Retweeted Marble Center
Combination drug therapy one biologics and one nano
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Aviva Lev-Ari Retweeted Koch Institute at MIT
Cutting Edge
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Adherence to medicine is another area where
#nanomedicine will likely be very important@JMaraganore#kisymposium. Indeed, area of great interest@kochinstitute w/ both nano and drug delivery devices -
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Always love
@KI_Nanomedicine’s Angela Belcher’s demos during her talks!@kochinstitute#KISymposium -
Aviva Lev-Ari Retweeted John Maraganore
Great Presentations at
#BIO2018 and great opinions expressed#KISYMPOSIUMAviva Lev-Ari added,
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Amazing early detection/diagnostics technology from Ralph’s Weissleder lab
@MGHCancerCenter: single cell, treatment informing Dx w/machine learning, as efficient as FACS but 1000x cheaper!#kisymposium@kochinstitute@KI_Nanomedicine -
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Learning how to translate technology from an incredible panel
@Alnylam@kochinstitute@KI_Nanomedicine#KIsymposium -
Aviva Lev-Ari Retweeted Anne E Deconinck
i agree
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Aviva Lev-Ari Retweeted Anne E Deconinck
Amazing panel
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Aviva Lev-Ari Retweeted Anne E Deconinck
Kendall square and Silicon Valley
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Tour-de-force talk by Jim Heath
@ISBUSA. Glad we recorded so many of today’s talks, definitely watching this one again!#kisymposium -
Aviva Lev-Ari Retweeted Koch Institute at MIT
A leader in n-dimensions
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Aviva Lev-Ari Retweeted Anne E Deconinck
Great role model, Paula Hammond
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Aviva Lev-Ari Retweeted Koch Institute at MIT
Best talk
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Na no na no, na no na no, hey hey, goodbye! Thanks to
@KI_Nanomedicine, our amazing speakers, our wonderful sponsors, and everyone who came out to learn about Breakthrough Cancer Nanotechnologies at#KIsymposium 2018. See you on June 14, 2019 for AI/machine learning in cancer! -
Aviva Lev-Ari Retweeted Koch Institute at MIT
Amazing man
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This next one’s going to get personal. James Heath of
@ISBUSA is taking “A Molecular View of Immuno-Oncology” with insight on how to personalize the field. We’re T-sold! (past tense of T-cell)#KIsymposium -
SYNOPSIS – 17th annual Summer Symposium: Breakthrough Cancer Nanotechnologies: Koch Institute, MIT Kresge Auditorium, June 15, 2018, 9AM-4PM
#kisymposium@PHARMA_BI@AVIVA1950 https://pharmaceuticalintelligence.com/2018/06/14/17th-annual-summer-symposium-breakthrough-cancer-nanotechnologies-koch-institute-mit-kresge-auditorium-june-15-2018-9am-4pm-2/ … via@wordpressdotcomTranslate Tweet
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Nanoscale will define many future discoveries 51% of the recently tenured SOS faculty – use nano 67% of the recently tenured SOE faculty with benefits – use nano
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @VladimirBulović -
Analytical Chemistry challenge:Fundamental Immunology Challenge CRISPR knocking out genes not for knocking in genes Mutated proteins and NEO antiagens: mostly computational task
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@JamesHeath -
ON CHIP RT-LAMP CONTROL: CANCER (red) VS NON-CANCER (blue) – FTIR Single cell spatial RNA Seq Hematology Analyzer – complete blood celll count vs Flow cytometry
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@RashidBashir, -
Cryo-section on microwell array, pixelate and fix tissue inside wells amplification reagents loaded on chip flow on chip On-chip RT-LAMP: Spatial fluorescence analysis
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@RashidBashir, -
liquid biopsy, molecualar analysis of the tumor spatial map of nuclei acids in tissue – Intra tumor heterogeniety subclonal genetic diversity in situ hybridization
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@RashidBashir, -
@SangeetaBhatia#Massbarcodes enable#multiplexing#Massencoded#synthetic#biomarkers Differentiating similar diseases with#proteaseactivity#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
@SangeetaBhatia multi-compartment modeling for predicting#PK Enhancing sensitivity by#nanosensorengineering for#ovariancancer#detection#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
Endoprotease Cancer: MMP9, MMP4 Synthetic Biomarkers Enzyme-responsive nanosensors PK switch Synthetic Biomarker paradigm for clinical decisions – Exogenous, multiples, urine
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@SangeetaBhatia, -
Team Science approache to effect the community @MichelleBradbury
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
@PaulaHammond @NoubarAfeyan Science must lead the way for translation and implementations, innovations IMPACT in academia on economy: MIT and Stanford in Sillicon Valley are leading the way#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
durability of nanoparticles in the body area we need more knowing FDA is developing new guidelines for nanotechnology policies will come from FDA soon
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @JohnMaraganore -
@JohnMaraganore company made decision to celebrate science by publishing research
@alnylam#augmentedreality @NOUBARAFEYAM: BIOLOGY DEVELOPED TOOL SETS THEY ARE EXAMPLES FOR NANO PARTICLES#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
potential becoming reality is in the hands of very able people working with people and other istitutionscreate robust designs partnering among roles
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@PaulaHammond @MichelleBradbury -
Notion of founding a company Investors some are scientists help develop companies while pursing science lip faith vs facts and quantification
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @NoubarAfeyan, -
Bringing therapeutics to tumor tissue
@BobLanger platform technology companies committed to bring cure#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@RobertLanger @johnmataganore@Alnylam @CristianneRijcken @CristalTherapeutics -
Diagnostics use of nanopartics by 7 developing companies
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @NoubarAfeyan -
Highly engineered particle encapsulated used in OR microdose in the past hospital setting finding optimal oncologies subtherapeutic properties cell death
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @MichelleSBradbury@MemorialSloan -
Panel on
#translations of#Nanomedicine to#patients#kisymposium@pharma_BI@AVIVA1950@BobLanger transformation of Biotech industry around@MIT like no elsewhere in the World -
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Are you going to
@kochinstitute‘s#KIsymposium tomorrow? Hear from@FlagshipPioneer CEO@NoubarAf, Bloomberg’s@beccabiotech, Alnylam’s@jmaraganore,@MIT‘s Robert Langer, and others. https://ki.mit.edu/news/symposium/2018 … -
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Angela Belcher (
@MITdeptofBE@KI_Nanomedicine) is sharing the stage with her portable, light-up bacteriophage to share “New Approaches for Finding Tiny Tumors: Towards Early Detection and Treatment of#ovariancancer” Ready, set, glow!#KIsymposium -
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Attending the 17th annual Cancer research symposium organized by
@kochinstitute. Interesting talk by Angela Belcher on finding tiny tumors.#KIsymposium@MIT -
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(gene) Silence, everyone! It’s time for
@KI_Nanomedicine member Dan Anderson (@MITChemE) to tell us about “Nanoparticle Formulations for RNA Therapy and Gene Editing.”#KIsymposium -
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@ben_ouyang and@TheChanLab taught me the importance of TAMs in tumour growth and NP delivery. The peptide developed by Suzie Pun that specifically targets M2 Mø has the potential to increase the efficiency of cancer nanotherapies#KIsymposium -
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Session II: Therapeutics continues with Suzie Pun (
@UW researcher and@KI_Nanomedicine scientific advisor) presenting on “Modulating Tumor-Associated Macrophages.” (Wait, was that a “macro” in the title? We thought#Kisymposium was all nano all the time this year!) -
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KI Director Tyler Jacks thanks this year’s
#KISymposium co-chairs: KI members Angela Belcher@MITdeptofBE,@snbhatia, director of@KI_Nanomedicine & Paula Hammond@MITChemE Dept head -
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50% HER2 positive will have brain metastesis BBB TfP Receptor-mediate Transcytosis: Antibody affinity Nanoparticles behave similarity to antibodies in the brain
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@MarkEDavis@Caltech -
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Excitement is “bubbling” after that first talk, but hold your questions for the break, please!
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S.S. Gambhir from
@StanfordMed uses ultrasound imaging of nanobubbles (with gas core and active targeting) to image cancer at molecular level. Q: Do changes in pressure in body affect quality of imaging?#KIsymposium -
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Heads up!
@Caltech‘s Mark Davis is talking about “Designing Nanoparticles to Safely Cross the Blood-Brain Barrier for Treating Brain Cancers”#KIsymposium -
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Yup, definite “props” to Angie for a dynamic engaging talk. Good science too. Very promising technology, data. Lots to discuss during the break.
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MD: Now moving into combo delivery with nanoparticle. Topo I and PARP toxicity so high when delivered in drug form, toxicity so high dosing had to be reduced to sub-efficacious levels. Now NCI study using delivery with nanoparticles to avoid tox
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Welcome and Intro to NanoMedicine with
@snbhatia@KI_Nanomedicine#kisymposium. -
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EBioMedicine Retweeted Claudia Schaefer
Our editor is at the
#kisymposium today@marblecenter@kochinstitute. This is what’s going on right now:EBioMedicine added,
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Our first speaker, Sanjiv Sam Gambhir
@Stanford talks Bubble Based Nanodiagnostics. Early detection = Prevention = deserves intense focus so we can save lives#kisymposium -
@DanielAnderson e-sgRNA – edited PCKS9- hyperlipidemia — Nanoparticle for in vivo Genome Editing RNA NANOTHERAPEUTICS AND CANCER Delivery to Immune system – Genome editing in vivo of CAR-Ts#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM -
Chylomicron metabolism: Mechanism of APoE mediated iLNP delivery siRNA in hypatocytes 5 genes silencing in lung endothelial cells IMMUNE CELLS AS A TARGET FOR siRNA
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@DanielGAnderson@IOM -
Immunomodulation – Macrophage targeting for TAM for Humans improve drug potency synthetic Nucleocapsids Biomaterials for modulating tumor extracellular matrix
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @SusieHPun@uwashington -
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17th annual Summer Symposium: Breakthrough Cancer Nanotechnologies: Koch Institute, MIT Kresge Auditorium, June 15, 2018, 9AM-4PM https://pharmaceuticalintelligence.com/2018/06/14/17th-annual-summer-symposium-breakthrough-cancer-nanotechnologies-koch-institute-mit-kresge-auditorium-june-15-2018-9am-4pm-2/ … via
@wordpressdotcom@aviva1950@pharma_BI -
#translational#diagnostics:#Precisiononcology (1) Imaging (2) Tumor biopsy (3) Liquid biopsy Enable earlier detection Visualization affordable cost @MGH#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @RalphWeissleder@MGHCancerCenter -
#Fallopiantubes maximum#reduction in#tumor better#survivalrate Pre-surgical planning locates hard-to-detect#ovariantumor – find tumors that are hidden#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@AngelaBelcher -
Bubble based Nanodiognostics: cancer location molecular events, atomical modelity Bubble size nanobubbles microbubbles targeted for Vascular Endothilium In vivo
#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM @SanjivSamGambhir@Stanford -
Nanotech, Diagnostics, Therapeutics, Cancer Care, Cancer Biology New Center for NanoMedicine
@MIT Prevention and early detection of Cancer for improved outcomes#Cancer#Nanotechnologies@kochinstitute#Kresge@MIT@Pharma_BI@AVIVA1950#KISYMPOSIUM@TylerJacks@SangeetaBhatia -
17th annual
#Summer#Symposium: Breakthrough#Cancer#Nanotechnologies:@KochInstitute,@MIT#KresgeAuditorium, June 15, 2018, 9AM-4PM https://pharmaceuticalintelligence.com/2018/06/14/17th-annual-summer-symposium-breakthrough-cancer-nanotechnologies-koch-institute-mit-kresge-auditorium-june-15-2018-9am-4pm-2/ … via@wordpressdotcom
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