Leaders in Pharmaceutical Business Intelligence (LPBI) Group

11:30AM 11/12/2014 – 10th Annual Personalized Medicine Conference at the Harvard Medical School, Boston

Reporter: Aviva Lev-Ari, PhD, RN

REAL TIME Coverage of this Conference by Dr. Aviva Lev-Ari, PhD, RN – Director and Founder of LEADERS in PHARMACEUTICAL BUSINESS INTELLIGENCE, Boston http://pharmaceuticalintelligence.com

11:30 Personalized Medicine Coalition Award &  Award Recipient Speech

Presentation of Personalized Medicine Coalition’s 10th Annual Award for Leadership in Personalized Medicine.

• was at Ely Lilly in the 70s leading supplier of Insulin in the 20s and antibiotics in the 30s,Factor 8, pain drugs, chemotherapy
• was at Genentech – Human growth Hormone and Human Insulin — both are PM, Interferon,
• was at Mayfield Ventures
• was at Millenium, CEO, early 90s, monoclonal antibodies
• 2000 discussion on the need for PMC
• Founder of Foundation Medicine – molecular informatics – expands therapeutics and PM
• NOW — with Third Rock Ventures, LLC

Mark Levin – award acceptance speech – Team accomplishments most important

We need to thank the patients participating in Clinical Trials

1. How I got involved in personalized medicine (PM): High School – Human Biology
2. Genetics – drive
3. PM – All diseases – genetic disorders — combination with extreme phenotyping, Muscular Dystrophy – splicing a gene for treatment
4. Drugability and PM – gene therapy, replace factor, deliver a gene to the brain and the drug. inside CSF
5. Gene editing – deliver to the Brain correct the gene in the Brain – therapy for ALS, Schizophrenia – understanding the genes involved in this disease, same
6. Cancer cure – treatment of combination therapies several at the same time vs present time treat one other emerges
7. cancer vaccine
8. Sample of blood – proteomics — in Annual Exams at MDs Annual physical
9. Convergent — comparison of Mutation across to 1000 patient’s mutations
10. Future is MOST exciting
11. Challenges of the Future: Biology and Technology, cells in microbiome, 10 million genes, SYSTEM BIOLOGY — will lead the way,
12. FUNDING SCIENCE via NIH Scientist is the most important National task
13. Preventative and Prognostics Medicine -need be part of DRUG development
14. Justification – maximize value for patient vs $$ spent – maximum value – waste and no leadership
15. Concern — Affordability of Healthcare to All, access to care vs economic Inequality
16. Leadership and Management: We truly need NATIONAL CONVERSATION — with a Leader with set of goals to solve a problem in certain time
17. Insurance, Pharma, HMO — budget challenge — attendees inn the room, need to provide leadership at the National Level

– See more at: http://personalizedmedicine.partners.org/Education/Personalized-Medicine-Conference/Program.aspx#sthash.qGbGZXXf.dpuf

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