11:30AM 11/12/2014 – 10th Annual Personalized Medicine Conference at the Harvard Medical School, Boston
Reporter: Aviva Lev-Ari, PhD, RN
REAL TIME Coverage of this Conference by Dr. Aviva Lev-Ari, PhD, RN – Director and Founder of LEADERS in PHARMACEUTICAL BUSINESS INTELLIGENCE, Boston http://pharmaceuticalintelligence.com
11:30 Personalized Medicine Coalition Award & Award Recipient Speech
Presentation of Personalized Medicine Coalition’s 10th Annual Award for Leadership in Personalized Medicine.
Mark J. Levin
Co-Founder and Partner
Third Rock Ventures, LLC
Presenter:
Brian Munroe
PMC Founder and Senior Vice President, Government Affairs
Endo
- was at Ely Lilly in the 70s leading supplier of Insulin in the 20s and antibiotics in the 30s,Factor 8, pain drugs, chemotherapy
- was at Genentech – Human growth Hormone and Human Insulin — both are PM, Interferon,
- was at Mayfield Ventures
- was at Millenium, CEO, early 90s, monoclonal antibodies
- 2000 discussion on the need for PMC
- Founder of Foundation Medicine – molecular informatics – expands therapeutics and PM
- NOW — with Third Rock Ventures, LLC
Mark Levin – award acceptance speech – Team accomplishments most important
We need to thank the patients participating in Clinical Trials
- How I got involved in personalized medicine (PM): High School – Human Biology
- Genetics – drive
- PM – All diseases – genetic disorders — combination with extreme phenotyping, Muscular Dystrophy – splicing a gene for treatment
- Drugability and PM – gene therapy, replace factor, deliver a gene to the brain and the drug. inside CSF
- Gene editing – deliver to the Brain correct the gene in the Brain – therapy for ALS, Schizophrenia – understanding the genes involved in this disease, same
- Cancer cure – treatment of combination therapies several at the same time vs present time treat one other emerges
- cancer vaccine
- Sample of blood – proteomics — in Annual Exams at MDs Annual physical
- Convergent — comparison of Mutation across to 1000 patient’s mutations
- Future is MOST exciting
- Challenges of the Future: Biology and Technology, cells in microbiome, 10 million genes, SYSTEM BIOLOGY — will lead the way,
- FUNDING SCIENCE via NIH Scientist is the most important National task
- Preventative and Prognostics Medicine -need be part of DRUG development
- Justification – maximize value for patient vs $$ spent – maximum value – waste and no leadership
- Concern — Affordability of Healthcare to All, access to care vs economic Inequality
- Leadership and Management: We truly need NATIONAL CONVERSATION — with a Leader with set of goals to solve a problem in certain time
- Insurance, Pharma, HMO — budget challenge — attendees inn the room, need to provide leadership at the National Level
– See more at: http://personalizedmedicine.partners.org/Education/Personalized-Medicine-Conference/Program.aspx#sthash.qGbGZXXf.dpuf
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