Leaders in Pharmaceutical Business Intelligence (LPBI) Group

AGENDA for microRNA Conference by CHI, March 16-17, 2015, Cambridge, MA

Reporter: Aviva Lev-Ari, PhD, RN

 

 

BIDMC’s Distinguished RNA Scientist, Dr. Frank Slack, to Deliver Presentation at Cambridge Healthtech Institute’s eleventh annual microRNA Conference. 

Dr. Slack, Director of Beth Israel Deaconess Medical Center’s new Institute for RNA Medicine, has led his team of molecular biologists in pioneering various aspects of the microRNA field and continues to make important contributions to this aspect of post-transcriptional control of gene regulation in stem cell development, cancer and aging.

Recent research has shown microRNAs to have tremendous potential as non-invasive biomarkers for the diagnosis and prognosis of disease, monitoring of treatment, and patient stratification. Cambridge Healthtech Institute’s Eleventh Annual microRNA as Biomarkers and Diagnostics will cover the latest developments in the use of microRNA in the early detection of disease for more effective treatment, monitoring tumor growth and disease progression, issues associated with microRNA measurement, and the potential for personalized medicine based on microRNA profile.

————————————————————————

Exosomal RNA/DNA in Cancer

• The Biology and Functional Contribution of Exosomes in Cancer Progression and Metastasis

Raghu Kalluri, M.D., Ph.D., Professor and Chair, Cancer Biology, University of Texas MD Anderson Cancer Center

• Exosomic microRNAs Affect the Biology of the Tumor Microenvironment

Muller Fabbri, M.D., Ph.D., Assistant Professor, Pediatrics and Molecular Microbiology & Immunology, University of Southern California Keck School of Medicine, Children’s Hospital Los Angeles

microRNA Biomarkers in Drug Development 

• Identification of Urinary microRNA Biomarkers of Glomerular Injury

Rounak Nassirpour, Ph.D., Principal Scientist, Investigative Pathology Laboratory, Drug Safety R&D, Pfizer

• MiRNAs as Circulating Biomarkers for Neurodegenerative Disorders

Pavan Kumar, Ph.D., Senior Scientist, Biomarkers and Personalized Medicine, Eisai

• MicroRNAs as Biomarkers in Clinical Fluids

Martin Beaulieu, Ph.D., Director, MicroMarkers™, Regulus Therapeutics

• MiRNAs as Biomarkers for Cancer Development and Drug Resistance

Bing-Hua Jiang, Ph.D., Professor, Pathology, Anatomy and Cell Biology, Thomas Jefferson University

• Universal Screening Test Based on Analysis of Circulating Organ-Enriched microRNAs

Kira Sheinerman, Ph.D., CEO, DiamiR Biosciences Corp.

microRNAs in Personalized Medicine 

• MiRNAs in Personalized Medicine: Hurdles and Possibilities

Omar Laterza, Ph.D., Director, Clinical Development Laboratory, Merck

• Circulating miRNAs in Autoimmune Disorders – Opportunities as Biomarkers for Patient Stratification and Challenges

Hungyun Lin, Ph.D., Principal Scientist, Drug Safety R&D, Pfizer

• MiRNA Biomarkers for Colorectal Cancers

Ajay Goel, Ph.D., Director, Epigenetics and Cancer Prevention, Baylor Research Institute

microRNA in Disease Diagnostics 

• Circulating miRNA Markers for Disease Diagnosis

Xuemei Zhao, Ph.D., Principal Scientist, Molecular Biomarkers and Diagnostics Laboratory, Merck

• MicroRNA Biofluid Profiles as Diagnostic Biomarkers in Epilepsy

David Henshall, Ph.D., Professor, Physiology & Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland

• Circulating microRNAs Show Promising Clinical Implications for Type 2 Diabetes

Elena Flowers, Ph.D., Assistant Professor, Physiological Nursing, University of California, San Francisco

Roundtable Discussions

• Topic 1: microRNA Normalization Strategy

Moderator: Christos Argyropoulos, M.D., Ph.D., University of New Mexico School of Medicine

• Topic 2: Quantitation Issues

Moderator: John Chevillet, Ph.D., Institute for Systems Biology

• Topic 3: Biomarker Biology: Delineating between Biomarkers that are the Drivers vs. Passengers in Disease Initiation, Progression and Maintenance

Moderator: Andrea Kasinski, Ph.D., Purdue University

microRNA as Predictive Cancer Biomarkers

Talk Title to be Announced

Frank J. Slack, Ph.D., Director, Institute for RNA Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School

• Tumor-Associated Circulating microRNAs as Biomarkers of Pancreatic Cancer

Subrata Sen, Ph.D., Professor and Deputy Chair, Translational Molecular Pathology, University of Texas MD Anderson Cancer Center

• MiRNAs as Predictors of Recurrence and Death in Melanoma

Iman Osman, M.D., Associate Director, NYU Cancer Institute & Professor, Oncology, and Director, NYU Interdisciplinary, Melanoma Coop Group, New York University Langone Medical Center

• MicroRNAs that Control the PI3K Survival Pathway

Andrei Thomas-Tikhonenko, Ph.D., Professor, Pathology and Laboratory Medicine, University of Pennsylvania

microRNAs in Cancer Pathways 

• Epigenetic Regulation of miRNAs in a Human T Cell Leukemia

Sundararajan Jayaraman, Ph.D., Clinical Associate Professor, Surgery, University of Illinois at Chicago

• A Combinatorial microRNA Therapeutics Approach to Eradicating Non-Small Cell Lung Cancer

Andrea Kasinski, Ph.D., Assistant Professor, Biological Sciences, Purdue University

• MicroRNA as Therapy – MRX34, a First-in-Human, First-in-Class microRNA Therapy in Advanced Cancer and Heme Malignancies

David S. Hong, M.D., Associate Professor and Chair, Investigational Cancer Therapeutics, University of Texas MD Anderson Cancer Center

Sponsored presentation opportunities are available.  For details, contact Carolyn Benton

 

CONFERENCE TRACKS

 

MARCH 16-17

Systems Biology, Evidence Synthesis and in silico Discovery Approaches to microRNA Biomarkers 

Executive ThinkTank: Development of Exosome-Based Diagnostics 

 

MARCH 17-18

RNA-Seq: A Fundamental Guide to the Field 

Circulating Nucleic Acid Biomarkers for Development of Non-Invasive Prenatal Tests

Separate registration is required.

SOURCE

From: microRNA as Biomarkers & Diagnostics <jaimeh@healthtech.com>

Date: Mon, 10 Nov 2014 10:30:00 -0500
To: <avivalev-ari@alum.berkeley.edu>
Subject: BIDMC’s Dr. Frank Slack to Deliver microRNA Research Updates