Irina Robu, PhD, Material Scientist and Business Developer for Materials Segment of Manufacturing Industry
Roles at Leaders in Pharmaceutical Business Intelligence
- Business Developer for RegenHU in the Tissue Engineering Industry in the US Mid West and Canada
- Business Developer for planned Global Distributorship of 3D Printing and related BioMedical Technologies, DBA, LM-3DP-GD based in the US, for the US Mid West and Canada
- Expert, Author, Writer in the following Research Categories
- Stem Cells for Regenerative Medicine
- Bone Disease and Musculoskeletal Disease
- Medical Devices: Stents and Tools
- Technology Transfer: Biotech and Pharmaceutical
- Nanotechnology for Drug Delivery
- Biomaterials
- Cell Therapy
- Tissue Engineering
- Medical Devices Design
UPDATED on 2/11/2020
IRINA ROBU, PhD
Ann Arbor, Michigan
Irina.robu@gmail.com
(m) 734-365-9015
BIO
Growing up, math and science have always been the subjects that I have excelled at. I found that I enjoy the simplistic facts and solutions of math and science. I always categorized myself as a logical thinker, so solutions often having an indisputable answer involving number or coming to conclusions based on facts and data are the most comprehensive reasoning for me. When I set my mind to solving a problem, I am determined to complete that task. With curiosity comes determination, which is a quality I apply to every aspect of my life. I initially completed my Bachelor of Science in Chemistry from University of Windsor with the intention of pursuing a medical degree, but realized that I enjoy learing how a system/machine works more. This lead me to pursue a Bachelor and Masters in Chemical engineering at Wayne State University in Detroit Michigan. It was there that I was exposed to the area of biomedical engineering , which is the subject that has always stimulated my curiosity.
It was there at Wayne State that I decided to pursue a PhD in Chemical engineering with area of specilization in tissue enginering and biomaterials. During my PhD, I I worked on assessing the growth, proliferation, adhesion, and spreading of SMCs and ECs on covalently immobilized GAG-chitosan material in-vitro, created and evaluated seeding efficiency of GAG-chitosan vascular graft and designed and evaluate a pulsatile bioreactor system for long-term 3D culture of large diameter tissue engineered constructs with efficient cell seeding, cell distribution and viability. I was able to improve cell seeding using collagen gel for vascular grafts and enhance their viability and survival in vitro as well as show that carboxymethylated dextran sulfate-chitosan/collagen material is a beneficial material for growing both endothelial and smooth muscle cells.
In the doctoral research phase of my studies I saw the high research potential for finding a treatment for cardiovascular disease, currently different approaches have been evaluated such as surgical procedures, organ transplantation, implantation of mechanical and synthetic devices and the administration of metabolic products. After completing my PhD, I pursued a post doctoral research position at IUPUI, Indianapolis where I looked to address the deficiencies of the current therapies for by taking a tissue engineering approach to regenerate bone for transplantation. In this approach, bone marrow mesenchymal stem cells harvested from animal model were used to generate transplantable tissue structures in culture. Parallel to this project I evaluated bioglass scaffolds seeded with a mixture of bone marrow derived mesenchymal stem cells and collagen in static, in perfusion system and in vivo conditions.
After my post doctoral studies, I had a chance to work a patent researcher at London IP in Michigan where I preformed qualitative analysis of patents and patent portfolios as well as delivered competitive intelligence to identify potential research.
Updated CV – 2/11/2020
Scientist with ability to lead scientific research and collaborate on a team to achieve scientific goals; develop methods and complete protocol design; execute and troubleshoot experiments; and provide statistical analysis and reporting of data in both written and oral reports. I am keen to utilize these skills in an industry setting in the next stage of my career.
EDUCATION
Ph.D. in Chemical Engineering (Biomaterials and Tissue Engineering Research)
Wayne State University, Detroit, MI
M.Sc. in Chemical Engineering (Laser Optics Research)
Wayne State University, Detroit, MI
B.Sc. in Chemical Engineering
Wayne State University, Detroit, MI
B.Sc. in Chemistry
University of Windsor, Windsor, Ontario, CA
PROFESSIONAL EXPERIENCE
Author/Writer for Leaders in Pharmaceutical Business Intelligence (LPBI) Group (Telecommute)
2013-Present
- 6 years of experience writing and editing curations, articles and regulatory documents on Biomaterials, Tissue Engineering, Stem Cells, Nanotechnology for Drug Deliver, Cell therapy and Technology Transfer.
- Excel at working with subject-matter experts to gather information, identify relevant data and audiences, and write documents that are clear and user friendly.
- Books where my articles appears:
VOLUME 2: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS & BioInformatics, Simulations and the Genome Ontology On Amazon.com since 12/28/2019
https://www.amazon.com/dp/B08385KF87
VOLUME 4: Medical 3D BioPrinting – The Revolution in Medicine, Technologies for Patient-centered Medicine: From R&D in Biologics to New Medical Devices. On Amazon.com since since 12/30/2017
https://www.amazon.com/dp/B078QVDV2W
Patent Researcher, Landon IP, Southfield, MI
2012-2013
- Conducted long-term patent landscape studies in biomedical engineering / chemical engineering / chemistry related fields to identify trends in such fields.
- Analyzed biomedical / chemical and biomedical device related databases (NCBI, PUB Med), IEEE journals, IEEE research papers, dissertations, thesis and other technical documentation for relevant prior art.
- Provided prior art search and expert written opinion in the form of international search report (ISR) PCT applications.
Postdoctoral Researcher, Indiana University-Purdue University, Indianapolis, IN
2011-2012
- Manage three projects simultaneously; prepare complex data findings, and present data to collaborators from several therapeutic areas, including Hematology/Oncology, Dental Materials and Biomedical Engineering.
- Developed an improved expansion protocols with human bone marrow mesenchymal stem cell and endometrial stem cells for bone tissue applications.
- Conducted independent research to examine the osteogenic differentiation potential of mesenchymal stem cell and endometrial stem cells to test its feasibility for bone tissue engineering applications.
- Conducted implant studies to check the effects of 3D cylindrical SLS scaffolds on bone formation in rats.
Graduate Research Assistant, Chemical Engineering, Wayne State University, Detroit, MI
2005–2011
- Managed daily operations of the lab including stock inventory, calibration/maintenance of equipment, training new lab members and mentored several undergraduate students.
- Coordinated and conducted all aspects of cell culture studies on immobilized glycosaminoglycan chitosan/collagen surfaces and vascular graft culture in a 3D bioreactor system research including study design, protocol writing, statistics, data analysis, report writing, presentation and publications.
- Developed an improved isolation and expansion protocols of ovine/bovine bone marrow-derived mesenchymal stem cells, blood vessels primary cells for cardiovascular tissue engineering applications.
- Investigated the effects of glycosaminoglycan (GAG) and GAG-like polyanion as modifiers for smooth muscle and endothelial cells activity by evaluating the effects of heparin, dextran sulfate immobilized on chitosan and chitosan-collagen films on morphology and proliferation of aortic cells.
- Designed and validated large-size custom bioreactor systems with controlled dynamic parameters to improve the cell functionality, seeding efficiency, and tissue
SELECTED PRESENTATIONS
- Robu I.S., Chu Tien-Min Gabriel., In Vivo Evaluation of Bioactive Glass Scaffolds through Selective Laser Sintering, World Biomaterials Congress 2012, poster #3006.
- Robu I.S., Walters H.L., Matthew H.W.T., Collagen Gel Effects on Smooth Muscle Cell Seeding Efficiency and Function in Chitosan Scaffolds, American Institute of Chemical Engineering 2009, Nashville, Tennessee; Oral Presentation in Biomaterial Scaffolds for Tissue Engineering.
- Robu I.S., Walters H.L., Matthew H.W.T., Collagen Gel Effects on Smooth Muscle Cell Seeding Efficiency and Function in Chitosan Scaffolds, Biomedical Engineering Society 2009, Pittsburg, Pennsylvania; Poster Presentation in Biomaterials for Tissue Engineering #2332.
- Robu I.S., Walters H.L., Matthew H.W.T., Development of a Chitosan Fiber-Reinforced, Large Vessel Graft for Pediatric Applications, Tissue Engineering & Regenerative Medicine International Society (TERMIS) North America 2008 Conference and Exposition, San Diego, California, poster # 622.
- Robu I.S., Walters H.L., Matthew H.W.T., A Fiber-Reinforced, Large Vessel Chitosan Scaffold for Pediatric Applications, American Institute of Chemical Engineers 2008, 30, Oral Presentation in Biomaterial Scaffolds for Tissue Engineering Section, 396f.
- Robu I.S., Walters H.L., Matthew H.W.T., Morphological and Growth Responses of Vascular Smooth Muscle Cells and Aortic Endothelial Cells Cultured on Immobilized Heparin and Dextran Sulfate Surfaces, TERMIS North America 2007 Conference and Exposition, Toronto, Canada, poster #1495.
- Robu I.S., Rothe Erhard W., Probes of Supercritical CΟ2 by Deflection of Multiple Beamlets; American Chemical Engineering Society Annual Meeting 2006, oral presentation.
PUBLICATIONS
- Irina Robu and David Orchard Webb, Manufacturability of Regenerative Medicine Products for Commercial Scale, Reference Module in Biomedical Sciences, Elsevier, October 2018.
- Larry H. Bernstein, Aviva Lev-Ari, Irina Robual. The Immune System, Stress Signaling, Infectious Diseases and Therapeutic Implications: VOLUME 2: Infectious Diseases and Therapeutics, Amazon Digital Services LLC. Kindle Edition. September 4, 2017.
- Robu I.S., Walters III Henry L., Matthew Howard W.T. Morphological and growth responses of vascular smooth muscle and endothelial cells cultured on immobilized heparin and dextran sulfate surfaces. J Biomed Mater Res Part A 2017:105A:1725–1735.
- Liu Wai Ching, Robu Irina, Patel Rikin, Leu Ming, Velez, Mariano, Chu, Tien-Min, The effects of 3D bioactive glass scaffolds and BMP-2 on bone formation in rat femoral critical size defects and adjacent bones, Biomedical Materials, Vol.9, Nr. 4, 2014 (* 50% contribution)
- Robu I.S., Walters H.L., Matthew H.W.T. Morphological and Growth Responses of Vascular Smooth Muscle Cells Cultured on Immobilized Heparin and Dextran Sulfate Surfaces; Transactions of the 32nd Annual Meeting of the Society for Biomaterials 2007, 30, p646.
- Robu I.S. and Erhard Rothe, Probes of supercritical CO2 by deflection of multiple beamlets, Journal of Flow Visualization & Image Processing, Vol. 12, pp. 1–11, 2005.
- Piparia R., Robu I.S, Matthew H.W.T. Optimizing Mechanical and Cell Adhesion Properties of Chitosan through Simultaneous Manipulation of Molecular Weight and Cross linking. Transactions of the 31st Annual Meeting of the Society for Biomaterials, 2006, 29: p278.
AWARDS
- Wayne State – Department of Chemical Engineering Teaching Assistantship (2007-2010)
- Perry Foundation Research Assistantship via Detroit Children’s Hospital (2005-2008)
- Graduate Research Fellowship, Industrial Manufacturing Research (2003-2005)
- Tissue Engineering and Regenerative Medicine Society Travel Award, Toronto (2007)
- Biomedical Engineering Society Travel Award Recipient, Pittsburgh (2009)
OLDER VERSIONS
Irina Robu, PhD
https://www.amazon.com/dp/B078QVDV2W
Available on Amazon.com, Kindle Store, since 12/30/2017
List of Posts on 3D BioPrinting in the Open Access Online Scientific Journal
http://pharmaceuticalintelligence.com
Curator: Aviva Lev-Ari, PhD, RN
3D Bioprinting Posts
· Development of 3D Human Tissue Models Awarded NIH Grants Worth $15M October 5, 2017
· Brain Surgeons Use 3D printing to PracticeOctober 4, 2017
· 3D-Printed Body Parts Could Replace Cadavers for Medical Training October 4, 2017
· First 3D Printed Tibia Replacement September 16, 2017
· 3-D Printing in Water with Novel Hybrid NanoparticlesSeptember 16, 2017
· 3-D Printed Ovaries Produce Healthy OffspringJuly 27, 2017
· 3D Printing Technique with Non-Contact Ultrasonic Manipulation TechnologyJune 27, 2017
· Stratasys Part of New CYBER Team for 3D Printed Orthotic Devices Targeting VeteransMarch 11, 2016
· World’s First 3D-printed ‘Sneezeometer’March 9, 2016
· New Scaffold-Free 3D Bioprinting Method Available to ResearchersFebruary 5, 2016
· 3-D Printing confirms physical model of brain foldsFebruary 1, 2016
· 3D Software Leads to Successful Jaw Replacement Surgery January 29, 2016
· Aprecia Pharmaceuticals Set to Advance 3D Printed Drug PipelineJanuary 29, 2016
· 3D “Squeeze” Helps Adult Cells Become Stem CellsJanuary 14, 2016
· Platform Technologies for Directly Reconstructing 3D Living Biomaterials January 13, 2016
· Low-cost 3-D printer-based organ model production technique January 11, 2016
· Materialise Partners with University of Michigan and Tissue Regeneration Services for Clinical Trials of 3D Printed Tracheal SplintDecember 26, 2015
· 3D Printer Breakthrough for Bone GraftsDecember 11, 2015
· 3D prints bacteria to create organically reactive materialNovember 8, 2015
· 3D bioprinted carbon nanotubes used to stimulate bone regrowthNovember 8, 2015
· New Spinal Cord Repair Strategy using 3D Cell GrowthOctober 31, 2015
· 3D printed microfibers used to reinforce hydrogelsOctober 27, 2015
· New technology for printing new tissues with living cellular bioink kitsOctober 23, 2015
· Silk Biomaterials Produced from 3D Bone Marrow Generate PlateletsOctober 23, 2015
· 3D-printed organ research enhanced with programmable DNA “smart glue”October 23, 2015
· Global 3D Bioprinting Market: Industry Size, Share and Segments Analysis to 2015 – 2021August 14, 2015
· Organs-on-Chips: An Alternative to 3D Bioprinting?August 13, 2015
· Chemical Giant BASF Teams With Poietis on 4D Bioprinted Skin ProjectAugust 13, 2015
· BioP3 technology could be an alternative to bioprinting organsAugust 13, 2015
· How to Feed Engineered Organs using a 3D Printed Sugar Network August 13, 2015
Non- 3D Bioprinting Posts
· Ferritin Cage Enzyme Encapsulation as a New Platform for NanotechnologyOctober 9, 2017
· Novel Blood Substitute – ErythroMerSeptember 17, 2017
· Walking DNA NanorobotSeptember 16, 2017
· First Haploid Human Stem CellsJuly 2, 2017
· Detecting Multiple Types of Cancer With a Single Blood TestJuly 2, 2017
· Nanostraws Developed at Stanford Sample a Cell’s Contents without DamageJune 27, 2017
· Cellular Guillotine Created for Studying Single-Cell Wound RepairJune 29, 2017
· Healing Side of Troublesome T CellsApril 24, 2016
· Google Glass Meets Organs-on-ChipsMarch 26, 2016
· Robotically Driven System Could Reduce Cost of Discovering DrugsMarch 15, 2016
· Fibrin-coated Electrospun Polylactide Nanofibers Potential Applications in Skin Tissue EngineeringMarch 1, 2016
· Cartillage Cells from Cow Knee Joints Used to Grow New Cartilage TissueJanuary 28, 2016
· Clinical Trials Could Lead to FDA Approval for Artificial PancreasJanuary 14, 2016
· Anti-diabetic Drugs Affect Gut bacteriaJanuary 12, 2016
· Nanoparticles Used to Levitate Cells in Tissue CultureJanuary 3, 2016
· The world’s most innovative intersection January 2, 2016
· Pennsylvania Supreme Court reverses Zimmer win in $20m knee implant lawsuitOctober 31, 2015
· Mass-producing stem cells to satisfy the demands of regenerative medicineOctober 28, 201
· Artificially intelligent synthetic skin interacts with brain cellsOctober 26, 2015
· Liver on the chip devices with the capacity to replace animal experimentsOctober 23, 2015
· Rat Hearts Healed by a Protein-rich GelOctober 5, 2015
· Newly discovered cells regenerate liver tissue without forming tumorsAugust 16, 2015
IRINA ROBU, PhD
[Email]: irina.robu@gmail.com [Cell]: (734)-365-9015
[Home]: (317)-222-1022
I am highly motivated researcher with strong passion in Biomaterials, Stem cells, Tissue engineering and Cell therapies. Equipped with the knowledge and technical skills in broad discipline topics (Biomaterials, Molecular Biology, Tissue Engineering, Chemistry and Chemical Engineering). I am keen to utilize these skills in an industry setting in the next stage of my career.
- BSc in Chemistry; BSc and MSc in Chemical Engineering; PhD in Chemical Engineering and minor in Biomedical Engineering.
- Familiar with GLP and GMP practices and FDA regulations.
- Strong knowledge of process optimization using statistical design of experiments (DOE), quality by design, data analysis using excel templates/macros and statistical analysis using Minitab and JMP.
- Hands on experience with mammalian and MSC stem cell culture/expansion, single use bioreactors (batch and perfusion), cell culture in 2D and 3D culture systems, cell based assays (proliferation/toxicity assays) and analytical protein assays (ELISA, Western Blot).
- Hand on experience with biomaterial (collagen, chitosan, bioglass, calcium phosphate) characterization, histomorphometry, micro-CT, XRD, GPC, microscopy (optical, fluorescence, SEM, TEM), viscometer, rheometer, tensile testing (MTS and Instron) and in vitro assays of biomaterials.
- Familiar with GLP and GMP practices and FDA regulations.
- Experience writing scientific manuscripts, standard operating procedures, batch records, reports, protocols, abstracts, presentation slides for seminars and conferences.
- Advanced proficiency with MS Office Suite (Excel, Word, Project, Powerpoint and Outlook) and image analysis software (Image J, Adobe Photoshop).
TECHNICAL SKILLS
Instrumentation
Microscopy (optical, fluorescence, SEM, TEM), UV Spectrophotometer, Fluorometer, X-ray Diffraction (XRD), Energy-dispersive X-ray spectroscopy (EDX), Tensile Testing Instruments (Instron, MTS), Freeze dryer, Refractometer, Viscometer, Evaporator, micro-CT and Microtome.
Molecular Techniques
ELISA, HPLC, RT-PCR, DNA isolation, Gel electrophoresis.
Biochemical Assays
Cell viability assays (Fluorescent: Alamar Blue, CyQuant; Colorimetric: MTT, XTT), Immunohistochemistry, Immunofluorescence,Stem cell differentiation assays, Material implantation and extraction and Histology.
Computer Skills
Sigma Scan Pro 5, Sigma Plot 2001, Origin 8, JMP 11, Image J, Endnote X2, Adobe Photoshop, Microsoft Office Package, Math Cad 2001, HYSIS, Minitab 14.
PROFESSIONAL EXPERIENCE
Expert Author/Writer for Leaders in Pharmaceutical Business Intelligence (Remote) 2013 – Present
Curated, authored, edited articles and regulation documents on the following Research Categories:
- Biomaterials
- Nanotechnology for Drug Delivery
- Cell Therapy
- Tissue Engineering
- Medical Devices
- Technology Transfer: Biotech and Pharmaceutical
Patent Researcher, Landon IP, Southfield, Michigan 2012-2013
- Performed qualitative analysis of patents and patent portfolios from, scientific, technical and business perspective.
- Analyzed biomedical / chemical and biomedical device related databases (NCBI, PUB Med), IEEE journals, IEEE research papers, dissertations, thesis and other technical documentation for relevant prior art.
- Provided prior art search and expert written opinion in the form of international search report (ISR) PCT applications.
Postdoctoral Researcher, Indiana University-Purdue University, Indianapolis, IN 2011 – 2012
- Manage three projects simultaneously; prepare complex data findings, and present data to collaborators from several therapeutic areas, including Hematology/Oncology, Dental Materials and Biomedical Engineering.
- Independently investigated the osteogenic differentiation potential of mesenchymal stem cell and endometrial stem cells to test its feasibility for bone tissue engineering applications using analysis such as flow cytometry, RT-PCR, histological analysis, immunofluorescence, SEM, cell based assays for proliferation and enzyme based assays.
- Planned and executed experiments to evaluate differentiation potential of MSC stem cells and endometrial cells by using techniques such as immunofluorescence microscopy, cell based assays for proliferation, migration, flow cytometry, SEM, enzyme based assays and histology.
- Conducted implant studies to check the effects of 3D cylindrical SLS scaffolds on bone formation in rats.
- Analyzed the 3D cylindrical bio-glass scaffolds pre-implantation using a) FTIR, XRD and SEM to assess their chemical bonding, composition and surface morphology of the scaffold and using MTS to assess their mechanical stability and post implantation a) histology to assess the presence of mineralized calluses bridging the gap of the segmental bone defects and b) verified the presence of tissue using micro-CT.
- Evaluated post dental implant tissue and post implant bioactive glass scaffold for bone resorption, mineral deposition, mechanical stability and tissue formation around the implant.
Graduate Research Assistant, Chemical Engineering, Wayne State University, Detroit, MI 2005 – 2011
- Managed daily operations of the lab including stock inventory, calibration/maintenance of equipment, training new lab members and mentored several undergraduate students.
- Independently coordinated and investigated all aspects of cell culture studies on immobilized glycosaminoglycan chitosan/collagen surfaces and vascular graft culture in a 3D bioreactor system research including study design, protocol writing, statistics, data analysis, report writing, presentation and publications.
- Investigated the effects of glycosaminoglycan (GAG) and GAG-like polyanion as modifiers for smooth muscle and endothelial cells activity by evaluating the effects of heparin, dextran sulfate immobilized on chitosan and chitosan-collagen films on morphology and proliferation of aortic cells.
- Designed and assembled continuous and perfusion bioreactor cell culture system with external gas and medium oxygenation capabilities for conducting in vitro biomaterials – cell interaction studies.
- Studied the effects of variable flow and medium composition (via perfusion bioreactor) on viability, morphology and metabolites.
Research Assistant, Chemical Engineering Department, Wayne State University, Detroit, MI 2003 – 2004
- Prepared and evaluated large density gradient experiments with compressible supercritical CO2 and calibrated single ray path inhomogeneous supercritical CO2.
Research Engineer, Detroit Edison -Warren Service Center, Detroit MI 2001 – 2003
- Responsible for the general lab support activities such as equipment maintenance and calibration.
- Conducted plant surveys of chemical usage for chemical consumption database and cost savings analysis.
- Designed and wrote a technical training manual for the Laboratory Information Management System (LIMS) program.
Research Assistant, University of Windsor, Chemistry, Windsor, Ontario, Canada 1998 – 2000
- Synthesized and characterize zirconium complexes using infrared spectroscopy, H-NMR and C-NMR and X-ray crystallography.
TEACHING/TRAINING EXPERIENCE
Graduate Teaching Assistant, Chemical Engineering, Wayne State University, Detroit, MI 2007-2008; 2009-2010
- Presented fundamental concepts and test strategies, graded student assignment and exams for Thermodynamics (CHE 3300) and Transport Phenomena (CHE 3200), Product and Process Design (CHE 4200) and Process Dynamics and Simulation (CHE 4600), Chemical process Integration (CHE 4800) and Material and Mass Balances (CHE 2800).
- Prepared course material including lectures, exams, homework, practice problems.
- Led weekly problem-solving sessions for a group of 12-24 students.
- Supervised students in their final exams, graded exams and weekly homework.
- Offered assistance with design project, HYSIS term project for Product and Process Design Class.
VOLUNTEER EXPERIENCE
- Contributing Volunteer Editor, MEDCRAVE: Advances in Tissue Engineering & Regenerative Medicine (ATROA) 2016-Present
EDUCATION
Ph.D. in Chemical Engineering (Biomaterials and Tissue Engineering Research)
Wayne State University, Detroit, MI May 2011
M.Sc. in Chemical Engineering (Laser Optics Research)
Wayne State University, Detroit, MI Dec 2004
B.Sc. in Chemical Engineering
Wayne State University, Detroit, MI May 2003
B.Sc. in Chemistry
University of Windsor, Windsor, Ontario, CA June 2000
SELECTED PRESENTATIONS
- Robu I.S., Chu Tien-Min Gabriel., In Vivo Evaluation of Bioactive Glass Scaffolds through Selective Laser Sintering, World Biomaterials Congress 2012, poster #3006.
- Robu I.S., Walters H.L., Matthew H.W.T., Collagen Gel Effects on Smooth Muscle Cell Seeding Efficiency and Function in Chitosan Scaffolds, American Institute of Chemical Engineering 2009, Nashville, Tennessee; Oral Presentation in Biomaterial Scaffolds for Tissue Engineering.
- Robu I.S., Walters H.L., Matthew H.W.T., Collagen Gel Effects on Smooth Muscle Cell Seeding Efficiency and Function in Chitosan Scaffolds, Biomedical Engineering Society 2009, Pittsburg, Pennsylvania; Poster Presentation in Biomaterials for Tissue Engineering #2332.
- Robu I.S., Walters H.L., Matthew H.W.T., Development of a Chitosan Fiber-Reinforced, Large Vessel Graft for Pediatric Applications, Tissue Engineering & Regenerative Medicine International Society (TERMIS) North America 2008 Conference and Exposition, San Diego, California, poster # 622.
- Robu I.S., Walters H.L., Matthew H.W.T., A Fiber-Reinforced, Large Vessel Chitosan Scaffold for Pediatric Applications, American Institute of Chemical Engineers 2008, 30, Oral Presentation in Biomaterial Scaffolds for Tissue Engineering Section, 396f.
- Robu I.S., Walters H.L., Matthew H.W.T., Morphological and Growth Responses of Vascular Smooth Muscle Cells and Aortic Endothelial Cells Cultured on Immobilized Heparin and Dextran Sulfate Surfaces, TERMIS North America 2007 Conference and Exposition, Toronto, Canada, poster #1495.
- Robu I.S., Rothe Erhard W., Probes of Supercritical CΟ2 by Deflection of Multiple Beamlets; American Chemical Engineering Society Annual Meeting 2006, oral presentation.
PUBLICATIONS
- Larry H. Bernstein, Aviva Lev-Ari, Irina Robu et al. The Immune System, Stress Signaling, Infectious Diseases and Therapeutic Implications: VOLUME 2: Infectious Diseases and Therapeutics, Amazon Digital Services LLC. Kindle Edition. September 4, 2017.
- Larry H. Bernstein, Aviva Lev-Ari, Irina Robu et al. Series E: e-Books on Patient-centered Medicine, VOLUME FOUR – Medical 3D BioPrinting – The Revolution in Medicine, Technologies for Patient-centered Medicine: From R&D in Biologics to New Medical Devices
https://pharmaceuticalintelligence.com/biomed-e-books/series-e-titles-in-the-strategic-plan-for-2014-1015/volume-four-medical-3d-bioprinting-the-revolution-in-medicine/ To be published on Amazon.com in 11/2017.
- Robu I.S., Walters III Henry L., Matthew Howard W.T. Robu IS, Walters HL, Matthew HWT. 2017. Morphological and growth responses of vascular smooth muscle and endothelial cells cultured on immobilized heparin and dextran sulfate surfaces.J Biomed Mater Res Part A 2017:105A:1725–1735
- Liu Wai Ching, Robu Irina, Patel Rikin, Leu Ming, Velez, Mariano, Chu, Tien-Min, The effects of 3D bioactive glass scaffolds and BMP-2 on bone formation in rat femoral critical size defects and adjacent bones, Biomedical Materials, Vol.9, Nr. 4, 2014 (* 50% contribution)
- Robu I.S., Walters H.L., Matthew H.W.T. Morphological and Growth Responses of Vascular Smooth Muscle Cells Cultured on Immobilized Heparin and Dextran Sulfate Surfaces; Transactions of the 32nd Annual Meeting of the Society for Biomaterials 2007, 30, p646.
- Robu I.S. and Erhard Rothe, Probes of supercritical CO2 by deflection of multiple beamlets, Journal of Flow Visualization & Image Processing, Vol. 12, pp. 1–11, 2005.
- Piparia R., Robu I.S, Matthew H.W.T. Optimizing Mechanical and Cell Adhesion Properties of Chitosan through Simultaneous Manipulation of Molecular Weight and Cross linking. Transactions of the 31st Annual Meeting of the Society for Biomaterials, 2006, 29: p278.
AWARDS
- Wayne State – Department of Chemical Engineering Teaching Assistantship (2007-2010)
- Perry Foundation Research Assistantship via Detroit Children’s Hospital (2005-2008)
- Graduate Research Fellowship, Industrial Manufacturing Research (2003-2005)
- Tissue Engineering and Regenerative Medicine Society Travel Award, Toronto (2007)
- Biomedical Engineering Society Travel Award Recipient, Pittsburgh (2009)
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