COVID-19 T-cell immune response map, immunoSEQ T-MAP COVID for research of T-cell response to SARS-CoV-2 infection

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COVID-19 T-cell immune response map, immunoSEQ T-MAP COVID for research of T-cell response to SARS-CoV-2 infection

November 20, 2020 by 2012pharmaceutical

COVID-19 T-cell immune response map, immunoSEQ T-MAP COVID for research of T-cell response to SARS-CoV-2 infection

Reporter: Aviva Lev-Ari, PhD, RN

Read our latest blog | T cells: Understanding Exposure and Immunity to COVID-19 by Adaptive Co-Founder and CSO, Harlan Robins. Read here

Watch the video

T cells are the adaptive immune system’s first responders to any virus, circulating in the blood to detect and quickly multiply to attack the virus, often before symptoms appear. Adaptive Biotechnologies’ unique MIRA Technology and immunoSEQ Technology has enabled us to create a comprehensive view of the T-cell response to SARS-CoV-2 infection. This data has been made public as part of the ImmuneCODE Initiative in order to help propel drug, vaccine, and clinical trial research. We are launching immunoSEQ T-MAP COVID with the tools to study and analyze the COVID-19 T-cell immune response map.

SARS-CoV-2-specific Antigen-TCR sequence-level data
Quantitative sequence level data for TCR repertoires for SARS-CoV-2 specific antigens

Monitor immunologic response to SARS-CoV-2 infection or vaccine
Track COVID-19 specific TCR sequences longitudinally

Dive into Patient, Population, or Cohort-level data
Determine TCR clones shared between cohorts & those that are Public vs Private clones

Learn more about the science behind the ImmuneCODE database in our first publication (Nolan et al.) and to discover initial COVID-19 data insights, read our recently updated pre-print publication (Snyder et al.)

A large-scale database of T-cell receptor beta (TCRβ) sequences and binding associations from natural and synthetic exposure to SARS-CoV-2

Magnitude and Dynamics of the T-Cell Response to SARS-CoV-2 Infection at Both Individual and Population Levels

End-to-end solution; from experimental design to publication ready data

SARS-CoV-2-specific TCR repertoire sequences & antigen data

✔ Validated TCR-antigen data from over 70 MIRA experiments

✔ In vivo identified SARS-CoV-2-specific TCR sequences

✔ TCR-Antigen sequence level data with the PCR, bias-controlled, reproducible immunoSEQ Assay

Data analysis through the immunoSEQ Analyzer or Computational Biology Services

✔ Explore SARS-CoV-2-specific TCR-Antigen sequence data in the immunoSEQ Analyzer

✔ Compare your COVID-19 samples against our COVID-19 samples to identify public vs private clones

✔ Computational Biology Services for COVID-19 data and Metadata analysis

Comprehensive COVID-19 TCR-Antigen sequence database

✔ Providing you a comprehensive view of SARS-CoV-2-specific antigen and TCR level data

✔ Database will constantly be updated with new findings and TCR-Antigen sequence data

Check out the publications below to learn how researchers are propelling their COVID-19 research by leveraging immunoSEQ T-MAP COVID and the ImmuneCODE COVID-19 database

Analysis of SARS-CoV-2 specific T-cell receptors in ImmuneCode reveals cross-reactivity to immunodominant Influenza M1 epitope

Watch our video, about how the immunoSEQ Technology and immunoSEQ T-MAP COVID can be used to better understand the immune response to SARS-CoV-2 infection.

Ready to learn more about how our immunoSEQ T-MAP COVID service can help you propel your research forward? Contact us below to speak with one of our experts.