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Diagnostic and Prognostic value of structural MRI: preliminary evidence of common and specific gray matter changes in Depression and Anxiety patients

Reporter: Aviva Lev-Ari, PhD, RN

Cortical thickening in the insular cortex, a brain region vital to perception and self-awareness in Patients with

• Social anxiety disorder (SAD)
• Major depressive disorder (MDD)

A greater cortical thickness may reflect a

• compensatory mechanism that is related to inflammation or other aspects of the pathophysiology,” she said.
• greater anterior cingulate cortical thickness could be the result of both the continuous coping efforts and emotion regulation attempts of MDD and SAD patients.”

Image Source: There are significant cortical thickness differences among the three groups. All regions survived clusterwise-correction (p<0.001).(Credit: Radiological Society of North America)

SOURCE

MRI Uncovers Brain Abnormalities in People with Depression and Anxiety

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