International Summit on Human Gene Editing: A Global Discussion, National Academy of Sciences, WashDC, December 1-3, 2015

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International Summit on Human Gene Editing: A Global Discussion, National Academy of Sciences, WashDC, December 1-3, 2015

November 30, 2015 by 2012pharmaceutical

International Summit on Human Gene Editing: A Global Discussion, National Academy of Sciences, WashDC, December 1-3, 2015

Reporter: Aviva Lev-Ari, PhD, RN

2.1.5.25

2.1.5.25 International Summit on Human Gene Editing: A Global Discussion, National Academy of Sciences, WashDC, December 1-3, 2015, Volume 2 (Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS and BioInformatics, Simulations and the Genome Ontology), Part 2: CRISPR for Gene Editing and DNA Repair

UPDATED ON 12/8/2015

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CRISPR Leaders Argue Against Total Ban on Human Germline Editing

Nov 30, 2015

a GenomeWeb staff reporter

NEW YORK (GenomeWeb) – As scientists from around the world prepare to discuss the implications of genome editing for both science and society, two leaders in the CRISPR/Cas9 field today published essays making the case against a ban on human germline editing.

Jennifer Doudna, of the University of California, Berkeley, and George Church, of the Wyss Institute for Biologically Inspired Engineering and Harvard Medical School, both highlighted the need for regulation, but to different ends. They published their opinions today in Nature.

Doudna argued for regulation to enforce what she hopes will be widely agreed-upon boundaries on genome editing research, especially on human germline editing. “A complete ban might prevent research that could lead to future therapies, and it is also impractical given the widespread accessibility and ease of use of CRISPR/Cas9,” she wrote.

SOURCE

https://www.genomeweb.com/gene-silencinggene-editing/crispr-leaders-argue-against-total-ban-human-germline-editing?utm_source=SilverpopMailing&utm_medium=email&utm_campaign=Daily%20News:%20Human%20Longevity%20Acquires%20Cypher%20Genomics%20-%2011/30/2015%2011:30:00%20AM

AGENDA

http://nationalacademies.org/cs/groups/genesite/documents/webpage/gene_168809.pdf

International Summit on Human Gene Editing: A Global Discussion Convened by: Chinese Academy of Sciences The Royal Society U.S. National Academy of Sciences U.S. National Academy of Medicine National Academy of Sciences Building 2101 Constitution Avenue, N.W. Washington, D.C. 20418 December 1-3, 2015

Agenda

Tuesday, 1 December 2015

7:00 am Registration/Continental Breakfast

8:00 am Welcome and Introductions Summit Committee Chair David Baltimore, California Institute of Technology

8:05 am Opening Remarks Congressman Bill Foster (D-11th District, Illinois) John P. Holdren, White House Office of Science and Technology Policy Representatives of the Convening Organizations: Ralph J. Cicerone, U.S. National Academy of Sciences Victor J. Dzau, U.S. National Academy of Medicine Zhihong Xu, Chinese Academy of Sciences John Skehel, The Royal Society 2

8:35 am Context for Summit Summit Planning Committee Chair David Baltimore, California Institute of Technology

8:45 am Context Through Three Lenses: Scientific, Historical, Legal Moderator: Ismail Serageldin, The Library of Alexandria Speakers: Klaus Rajewsky, Max Delbrück Center for Molecular Medicine Daniel J. Kevles, New York University Alta Charo, University of Wisconsin, Madison

9:40 am Scientific Background on Gene Editing Technologies

Moderator: Jennifer A. Doudna, University of California, Berkeley

Speakers: Maria Jasin, Memorial Sloan Kettering Cancer Center Emmanuelle Charpentier, Max Planck Institute of Infection Biology Jin-Soo Kim, Seoul National University / Institute for Basic Science Jonathan Weissman, University of California, San Francisco Discussants: J. Keith Joung, Massachusetts General Hospital and Harvard Medical School Bill Skarnes, Wellcome Trust Sanger Institute Feng Zhang, Broad Institute of Harvard and MIT

11:05 am Comments from the Floor

11:30 am Lunch 1:00 pm Applications of Gene Editing Technology: Human Germline Modification

Moderator: Robin Lovell-Badge, The Francis Crick Institute

Speakers: Peter Braude, King’s College London Kyle Orwig, University of Pittsburgh George Q. Daley, Boston Children’s Hospital Discussants: George Church, Harvard Medical School Azim Surani, Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge

2:30 pm Comments from the Floor 3

3:00 pm Break

3:30 pm Societal Implications of Emerging Technologies

Moderator: Annelien L. Bredenoord, University Medical Center Utrecht Speakers: John Harris, University of Manchester Hille Haker, Loyola University Chicago Marcy Darnovsky, Center for Genetics and Society Sharon F. Terry, Genetic Alliance

4:30 pm Comments from the Floor

5:15 pm Limits to Our Understanding Speaker: Eric Lander, Broad Institute of Harvard and MIT

5:45 – 7:00 pm Breakout Sessions

6:30 Reception 8:00 pm Adjourn

Wednesday, 2 December 2015

8:30 am Applications of Gene Editing Technology: Basic Research

10:15 am Applications of Gene Editing Technology: Somatic Cell Therapy

1:30 pm Governance at the Institutional and National Level

3:00 pm Governance at the International Level

4:30 pm International Perspectives

Thursday, 3 December 2015

8:40 am Interrogating Equity