Posts Tagged ‘bioprinter’

New Scaffold-Free 3D Bioprinting Method Available to Researchers

Reporter: Irina Robu, PhD


UPDATED ON 2/6/2016



Bio 3D Printer Regenova with Kenzan method



Cyfuse and Cyberdyne Are Pushing the Boundaries of 3D Printed Human Engineering With Regenova

by TE Halterman | Mar 3, 2015 | 3D Printers3D PrintingHealth 3D Printing |






New scaffold-free 3-D bioprinting method available for first time in North America

Cell Applications primary cells and Regenova 3D Bio Printer from Cyfuse Biomedical combine to print robust 3-D tissue without introduction of extraneous scaffolding material



Regenova, Bio 3D Printer by Cyfuse


Cyfuse Biomedical K.K. and Cell Applications.Inc. publicized on February 3, 2016 that advanced tissue engineering services using 3D bioprinting approach will be available in North America. The services involved using Cyfuse Biomedica’s Regenova 3D Bio Printer, a state of the art robotic system that produces 3D tissues from cell and Cell Applications has created a pay by service bio-printing model that produces scaffold-free tissue available immediately to scientists in the U.S. and Canada for research use.

According to James Yu, Founder and CEO of Cell Applications having the Regenova 3D Bio Printer at our San Diego headquarters offers researchers an end-to-end, customized solution for creating scaffold-free, 3D-engineered tissues that diminish costs by reducing the lengthy processes typical in pharmaceutical drug discovery. In addition , Koji Kuchiishi, CEO of Cyfuse Biomedical having the Regenova 3D Bio Printer, combined with Cell Applications’ comprehensive, high-quality primary cell bank, offers researchers streamlined access to a nearly limitless selection of three dimensional tissues including those mimicking blood vessels, human neural tissue and liver constructs.

Unlike the other bioprinters on the market the bio-printer made by Regenova does not depend on scaffolding made of biomaterials such as collage or hydrogel to construct 3D tissue, the instrument assembles three dimensional microscopic tissue by forming spheroids, one at the time and lancing them on a fine needle array. The spheroids are guided by pre-programmed software which can be design and constructed into rods, spheres, tubes, sheets and other tissue configurations. In order for the engineered tissue to mature a bioreactor chamber is used. As the cells mature, they self-organize promoting strong, reliable tissue that can be further optimized by design of bio printer’s needle array that allows for optimum circulation of culture medium.


Read Full Post »

3D Prints Bacteria to Create Organically Reactive Material

Reported by : Irina Robu, PhD


The invention at MIT Media Lab is unique because unlike other typical 3D printing projects, the reactive material isn’t implemented as a non-printed component instead the organic material, bioLogic is a 3D printing bacterial cells called nato, a microorganism found in dry rice stalks.

What makes this material unique and ideal as a reactive material is the ability to expand and contract, depending on the moisture of the surrounding environment. The natto cells were first grown within the MIT bio lab and characterized with AFM in order to reach nano resolution, where the resulting bacterial material is extruded onto the bioLogic ‘bio-skin’, with a micron-resultion bioprinter.

The garment used by bioLogic team is infused with the 3D printed natto cells, which allows the tight-fitting ’Second Skin’ garment to transform and respond to the wearer’s body heat and sweat. Once the natto-infused bio-skin is  impacted with the wearer’s body heat. The MIT Lab bioLogic team is in collaboration with New balance on the ‘Second Skin’ project, giving a potential real world application for this bacterial material within fashion industries.

The MIT Media Lab team has also shown other ways that this bio-hybrid film can be used beyond the “Second Skin”. This material can be utilized for shape and color changing, such as a tea leaf infused with the natto material that is able unfold when the tea is hot and ready. The microorganism-based material shows that organically-based materials can work as a reactant just as well as sensors and other non-printed components.




Read Full Post »