Technion Prof. Emeritus Yoram Palti of the Faculty of Medicine will receive the 2022 Israel Prize in the Field of Entrepreneurship and Technological Innovation

Feeds:: Posts; Comments

« Bipolar Disorder now understood by Markers Identified of the Gene Expression for this Diagnosis

AI enabled Drug Discovery and Development: The Challenges and the Promise »

Technion Prof. Emeritus Yoram Palti of the Faculty of Medicine will receive the 2022 Israel Prize in the Field of Entrepreneurship and Technological Innovation

March 13, 2022 by 2012pharmaceutical

Technion Prof. Emeritus Yoram Palti of the Faculty of Medicine will receive the 2022 Israel Prize in the Field of Entrepreneurship and Technological Innovation

Reporter: Aviva Lev-Ari, PhD, RN

Prof. Emeritus Yoram Palti of the Ruth and Bruce Rappaport Faculty of Medicine will receive the 2022 Israel Prize in the Field of Entrepreneurship and Technological Innovation. Prof. Palti developed groundbreaking cancer treatments that fight malignant brain tumors using electric pulses in a non-invasive manner.

SOURCE

https://mailchi.mp/technion/shaping-the-future-of-the-technion?e=d234e13770

An Interview and the milestones of the technology development is described in a Journal article

From the basement in Israel – to a global medical revolution: the innovative treatment of life-prolonging cancer

SOURCE

https://www.mako.co.il/news-n12_magazine/2021_q3/Article-2329c13a68afb71026.htm

Core Technology

The idea behind Tumor Treating Fields is simple yet ingenious: We harness basic physical principles using electric fields to disrupt cancer cell division.—

Uri Weinberg,
Chief Science Officer

Tumor Treating Fields utilize the natural electrical properties of dividing cancer cells

Cellular proteins such as tubulin and septin are strongly affected by Tumor Treating Fields because they are highly polar, containing both positive and negative charges. During cell division, tubulin and septin must position themselves in a particular way in order for the cell to divide. Tumor Treating Fields exert forces on tubulin and septin, preventing them from moving to their correct locations and disrupting cancer cell division.

Normal Cancer Cell Division

Image Source: https://www.novocure.com/our-therapy/

Effect of Tumor Treating Fields

Image Source: https://www.novocure.com/our-therapy/

Novocure.com

We are striving to extend survival in some of the most aggressive forms of cancer.

In 2000, Yoram Palti, our founder and professor emeritus of physiology and biophysics at the Technion — Israel Institute of Technology, sought to leverage his expertise in biophysics to develop a new way to treat solid tumor cancers that would destroy tumor cells while sparing healthy tissue and avoiding many of the life-altering side effects of existing cancer therapies.

He set up a laboratory in his basement to explore the potential of electric fields as a treatment for solid tumors.

Professor Palti founded Novocure to provide patients with a new cancer treatment based on his hypothesis, since proven, that alternating electric fields, when applied at specific frequencies, can disrupt cancer cell division. This innovative treatment, Tumor Treating Fields, is a completely different approach to cancer therapy.

“Nobody understood what I was doing,” Professor Palti said of his early development of Tumor Treating Fields.

Palti’s initial research from his basement laboratory evolved to become Novocure – an international oncology company with more than 1,000 employees and operations in North America, Europe, the Middle East and Asia.

Our company began with a patient-forward approach that continues to drive our mission today. With more than 20 years of research and many significant milestones, we believe we are only beginning.

Read more …

SOURCE

https://www.novocure.com/about-us/