Biology of aging research goal: Defeating Death – California Life Company (Calicolabs.com), A Billion-dollar Longevity Lab, since 2013, GOOGLE cofounder and CEO Larry Page, formation of a new Alphabet entity is using consumer genetics and genealogy firm Ancestry’s forest of family trees | Leaders in Pharmaceutical Business Intelligence (LPBI) Group

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Biology of aging research goal: Defeating Death – California Life Company (Calicolabs.com), A Billion-dollar Longevity Lab, since 2013, GOOGLE cofounder and CEO Larry Page, formation of a new Alphabet entity is using consumer genetics and genealogy firm Ancestry’s forest of family trees

November 6, 2018 by 2012pharmaceutical

Biology of aging research goal: Defeating Death – California Life Company (Calicolabs.com), A Billion-dollar Longevity Lab, since 2013, GOOGLE cofounder and CEO Larry Page, formation of a new Alphabet entity is using consumer genetics and genealogy firm Ancestry’s forest of family trees

Reporter: Aviva Lev-Ari, PhD, RN

Conclusion – “Don’t smoke, and don’t go to war.”

Humans have more control over how long they live than their genes do. It’s all the other things that families share—homes and neighborhoods, culture and cuisine, access to education and health care—that make a much bigger difference in the set of numbers that might one day grace your tombstone.

Analyzing the pedigrees of more than 400 million people who lived and died in Europe and America going back to 1800 was that although longevity tends to run in families, your DNA has far less influence on how long you live than previously thought. The results, published Tuesday in the journal Genetics, is the first research to be made public from the collaboration, which ended quietly in July and whose terms remain confidential.

“The true heritability of human longevity for that cohort is likely no more than seven percent,” says Ruby. Previous estimates for how much genes explain variations in lifespan have ranged from around 15 to 30 percent. So what did Ruby uncover that previous studies had missed? Just how often amorous humans go against the old adage that “opposites attract.”

For example, you might choose a partner who also has curly hair, and if the curly-haired trait winds up being somehow associated with long lifespans, this would inflate estimates of lifespan heritability passed on to your kids. Same thing for non-genetic traits like wealth, education, and access to good health care. People tend to choose partners in their same income bracket with the same terminal degree, both of which are associated with living longer, healthier lives.