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@Pharma_BI #WMIF17 @AVIVA1950 Medical Devices – Prevention methods, Big data , AI, Heart Failure a role for Government like “CVD Moonshot”

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@Pharma_BI @AVIVA1950 #WMIF17 a working artificial heart is more needed than another stent, personalized sensors (diagnostics) reimbursment

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@pharma_BI @AVIVA1950 #WMIF17 Monetizing Diagnostics is key no reimbursement for regenerative medicine, biological system vs physical system

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@Pharma_BI #WMIF17 Bruce Rosengard: Crowd sourcing future mechanism for funding innovations vs ROI funding, Partnerships Academia/Industry

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@pharma_BI @AVIVA1950 #WMIF17 E. Edelman: Ideas start in Academia, Residential teaching is eroding, Industry needs assuming role of Academia

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@Pharma_BI #WMIF17 Ronald Tompkins, MD: Regulatory FDA/Bureaucracy needs be non-adversarial relations with Hospitals or Academia or industry

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@Pharma_BI @AVIVA1950 #WMIF17 Timothy Ring, CEO, Bard: corporate controlled fund for acquisions rely on Start up community for acquisitions

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@Pharma_BI, #WMIF17 Michael Mussallem CEO, Edwards Lifesciences Selling services – heart-lung machine: Perfusion is a product and Service

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@Pharma_BI #WMIF17 Lewis Sandy, MD UnitedHealth 30% of care cost is WASTE, eliminate!! Collaborations Pharma Devices: Data Analytics KEY

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@Pharma_BI #WMIF17 @AVIVA1950 Jagmeet Singh, MGH Genetic profiling for early detection, Going upstream for the Genetics and the Prevention

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@Pharma_BI #WMIF17 Omar Ishrak, PhD CEO, Medtronic Innovations are the essence of Medical Devices development as mission in technology

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@Pharma_BI #WMIF17 Omar Ishrak, CEO, Medtronic Training Challenge Surgical Robotic patient comfort of minimal invasive therapy, cost lower

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@Pharma_BI #WMIF17 Omar Ishrak, CEO, Medtronic Mitral Valve – platform for new generation of diagnostics ETERNAL: recover fast outcome

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@Pharma_BI #WMIF17 Marc Semigran Myokardia Preclinical trials for early insights for Younger patient with cardiomiopaty and older patient

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@Pharma_BI #WMIF17 Makoto Suematsu initiative on Dementia, cases of +100 y-o without functional decline in Japan

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@Pharma_BI #WMIF17 @AVIVA1950 Makoto Suematsu, collaboration with NIH, Beyond the Border Masanori Aikawa AGING disease indication is novel

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@Pharma_BI #WMIF17 Innovations from Japan leveraged in a global corporation, Bayer, Academia and Industry Partnership investment from Bayer

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@Pharma_BI #WMIF17 @AVIVA1950 Makoto Suematsu, Pharma’s difficulty to data access the clinical data from Academic Hospitals, gov’t IT invest

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@Pharma_BI #WMIF17 Carsten Brunn, Bayer Osaka Innovation Center to facilitate Translational results transfer to Pharma, stem cell initiative

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@Pharma_BI @AVIVA1950 #WMIF17 Hiroyuki Kawabata rate of CVD and HTN increased in Japan with aging population, national goal decrease BP

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@Pharma_BI @AVIVA1950 #WMIF17 Benjamin Scirica, FDA requires PRAGMATIC TRIAL DESIGN, IDENTIFY DIFFERENT POPULATION FOR EXISTING DRUGS,

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@Pharma_BI #WMIF17 Rowe of Edwards Mitral Valve Trans catheter is the direction PATIENT ACCESS – who will benefit devices Improve Patient

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@pharma_BI @AVIVA1950 #WMIF17 Cost of failure for AD at Eli Lilly, reduce failure rate, hedge bets to cut losses, investment may be deadend

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#WMIF17 @Pharma_BI @AVIVA1950 Offset AD prevent vs delay age of onsett is desirable, Pharma spend $70Billion on R&D, most is D NIH is R

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#WMIF17 @pharma_BI, @AVIVA1950, Increase Research at Eli Lilly CEO, medicine will bring value, can’t apologies for drug failure, best time

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#WMIF17 @Pharma_BI @AVIVA1950 Stanley Shaw, MD, PhD Realization by physicians that monitoring Patients @Home is a TIME SAVER – tech adopted

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#WMIF17 @pharma_BI Stanley Shaw Trusted Sources for Sharing genetic information with Academic Centers: Verily, AstraZeneca, AHA partnership

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#WMIF17 @pharma_BI @AVIVA1950 Jonathan Rennert: histories of ECG before cardiac arrest: instruct do not drive, do not be alone at home

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#WMIF17 @pharma_Bi @AVIVA1950 Joe Kvedar, MD Implement technology for quality care, access and lower cost monitoring Patients while @Home

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#WMIF17 @Pharma_BI @AVIVA1950 Robert Bradway CEO, Amgen Value of innovation at a price that allows access and lowering cost of care

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#WMIF17 @Pharma_BI @AVIVA1950 Robert Bradway CEO, Amgen Cardiologist prescribed the medication for himself 6 month for insurance approval

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@pharma_BI @AVIVA1950 #WMIF17 Norman Stockbridge, MD, PhD Director, Division of CV and Renal Products, FDA: Preserve randomization is key

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@pharma_BI @AVIVA1950 #WMIF17 Elisabeth Björk, AstraZeneca asked Norman Stockbridge, FDA – pragmatic design avoid missing data is 12%

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@pharma_BI @AVIVA1950 #WMIF17 Scott Wasserman, Amgen, AI will become part of Clinical Trial Design for investigational therapies and others

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@pharma_BI @AVIVA1950 #WMIF17 Dean Li, Merck, Arrhythmia: Mutation if down played causes Arrhythmia if Overexpressed causes Arrhythmia

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@pharma_BI @AVIVA1950 #WMIF17 Sean Harper, MD, Amgen in CVD complex traits phynotype more determinative then genotyping vs Oncology,

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@pharma_BI @AVIVA1950 #WMIF17 Sean Harper, MD, Amgen Sean Harper, MD Investors:to Biotech – works on Oncology and on Orphan drugs

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@pharma_BI @AVIVA1950 #WMIF17 Jean-François Formela, MD Coolest technology: CRISPR one injection reduction of effects in a genetic disease

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Aviva Lev-Ari‏ @AVIVA1950 16h16 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Highlights – LIVE Day 2: World Medical Innovation Forum – https://pharmaceuticalintelligence.com/2017/05/02/highlights-live-day-2-world-medical-innovation-forum-cardiovascular-%e2%80%a2-may-1-3-2017-boston-ma-%e2%80%a2-united-states/ … via @Pharma_BI

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@pharma_BI @AVIVA1950 #WMIF17 Ecosystem: Products, Patient Advocacy Groups and Regulators –alignment interaction among agencies: NIH, FDA

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Aviva Lev-Ari‏ @AVIVA1950 16h16 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Investment in Devices looks better vs CVD Drugs, Biologics are different, Nurtaceuticals some are harmful

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Aviva Lev-Ari‏ @AVIVA1950 16h16 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Robert Califf, Precision Medicine is over inflated except in Oncology, “in CVD, I wish to hear from you”

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Aviva Lev-Ari‏ @AVIVA1950 15h15 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Jessica Mega CMO Verily, Real Time monitoring, each Patient has own Portal, monitoring takes major resources

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Aviva Lev-Ari‏ @AVIVA1950 15h15 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Michael Mahoney: Challenges in Emerging Markets: China more regulation India – price very low expensive stent

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Aviva Lev-Ari‏ @AVIVA1950 15h15 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Microelectronics new direction: Endoscopy GI Pulmonary,SPINAL CORD STIMULATION: GU GI (Crohn),Neuromodulation

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@pharma_BI @AVIVA1950 #WMIF17 Aarif Khakoo, MD Amgen 1,500,000 stroke Genetics will bring the breakthrough to atherosclerosis

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@pharma_BI @AVIVA1950 #WMIF17 Craig Sponseller, Is triglycerides the right focus, Macrophage activation to prevent pathways resistance

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@pharma_BI @AVIVA1950 #WMIF17 Aarif Khakoo, MD Amgen Cost is related to FAIL less – target selection is cardinal

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@pharma_BI @AVIVA1950 #WMIF17 Clive Meanwell, Phase III needs different questions and more Phase IV needed

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@pharma_BI @AVIVA1950 #WMIF17 Campbell Rogers, MD Clinical burden remains: Value for Patient economic value of the outcome of the

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@pharma_BI @AVIVA1950 #WMIF17 Campbell Rogers, MD Imaging Efficiency free cost Plaque composition Coronary CT flow implication of stenosis

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Aviva Lev-Ari‏ @AVIVA1950 13h13 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Craig Sponseller, MD Pragmatic Clinical Trial Design: Novel Targets, collaboration of Academia and Industry

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@pharma_BI @AVIVA1950 #WMIF17 Gary Gibbons Reinvent Longitudinal Cohort Studies & Genomics sequencing – Concepts of Data Commons Analytics

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Aviva Lev-Ari‏ @AVIVA1950 13h13 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Gary Gibbons 20% investigators take up 50% of the grants squeezing out the bandwidth need younger generation

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Aviva Lev-Ari‏ @AVIVA1950 13h13 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Gary Gibbons, MD Pragmatic optimist in this position, scientists innovate for Patients would do it again

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Aviva Lev-Ari‏ @AVIVA1950 11h11 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Highlights LIVE Day 3: World Medical Innovation Forum – CARDIOVASCULAR https://pharmaceuticalintelligence.com/2017/05/03/highlights-live-day-3-world-medical-innovation-forum-cardiovascular-%e2%80%a2-may-1-3-2017-boston-ma-%e2%80%a2-united-states/ … via @Pharma_BI

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Aviva Lev-Ari‏ @AVIVA1950 11h11 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Disruptive Dozen 1. Quantitative Molecular Imaging for Cardiovascular Phynotypes

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Aviva Lev-Ari‏ @AVIVA1950 3h3 hours ago

@pharma_BI @AVIVA1950 #WMIF17 Disruptive Dozen 2. Harnessing Big Data and Deep Learning for Clinical Decision Support

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@pharma_BI‏ @Pharma_BI 3h3 hours ago

Highlights LIVE Day 3: World Medical Innovation Forum – CARDIOVASCULAR • MAY 1-3, 2017 BOSTON, MA • UNITED STATES

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Aviva Lev-Ari‏ @AVIVA1950 3h3 hours ago

Highlights LIVE Day 3: World Medical Innovation Forum – CARDIOVASCULAR • MAY 1-3, 2017 BOSTON, MA •… https://pharmaceuticalintelligence.com/2017/05/03/highlights-live-day-3-world-medical-innovation-forum-cardiovascular-%e2%80%a2-may-1-3-2017-boston-ma-%e2%80%a2-united-states/ … via @Pharma_BI

Aviva Lev-Ari‏ @AVIVA1950 22h22 hours ago

Highlights – LIVE Day 2: World Medical Innovation Forum – CARDIOVASCULAR • MAY 1-3, 2017 BOSTON, MA… https://pharmaceuticalintelligence.com/2017/05/02/highlights-live-day-2-world-medical-innovation-forum-cardiovascular-%e2%80%a2-may-1-3-2017-boston-ma-%e2%80%a2-united-states/ … via @Pharma_BI

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Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @Pharma_BI @AVIVA Frans van Houten CEO, Philips eICU -measure evolution to forcast 6 hours a deterioration reduction 40% of death

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF @pharma_BI @AVIVA1950 Robert Bradway Future at Amgen: Coming drug is Pharmcogenetics for atherosclerosis

LikeAviva Lev-Ari‏ @AVIVA1950 May 2

Robert Bradway CEO, Amgen Pay for benefit, for outcome, no pay if med does not do what it was supposed to do – REFUND patients poor outcome

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @Pharma_BI @AVIVA1950 Robert Bradway CEO, Amgen Cardiologist prescribed the medication for himself 6 month for insurance approval

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @Pharma_BI @AVIVA1950 Robert Bradway CEO, Amgen Value of innovation at a price that allows access and lowering cost of care

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @pharma_Bi @AVIVA1950 Joe Kvedar, MD Implement technology for quality care, access and lower cost monitoring Patients while @Home

1 retweet

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @pharma_BI @AVIVA1950 Jonathan Rennert: histories of ECG before cardiac arrest: instruct do not drive, do not be alone at home

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @pharma_BI Stanley Shaw Trusted Sources for Sharing genetic information with Academic Centers: Verily, AstraZeneca, AHA partnership

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Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @Pharma_BI @AVIVA1950 Stanley Shaw, MD, PhD Realization by physicians that monitoring Patients @Home is a TIME SAVER – tech adopted

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Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @pharma_BI, @AVIVA1950, Increase Research at Eli Lilly CEO, medicine will bring value, can’t apologies for drug failure, best time

1 retweet

Aviva Lev-Ari‏ @AVIVA1950 May 2

#WMIF17 @Pharma_BI @AVIVA1950 Offset AD prevent vs delay age of onsett is desirable, Pharma spend $70Billion on R&D, most is D NIH is R

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