Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia

Reporter: Aviva Lev-Ari, PhD, RN

Watch Video

https://www.youtube.com/v/n1VgTSondUE?fs=1&hl=fr_FR

Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeabil…

Sourced through Scoop.it from: www.youtube.com

See on Scoop.it – Cardiovascular and vascular imaging

Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids;

• an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient’s immune system, and therefore the risk of organ rejection. Also
• causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as
• an antifungal agent,
• an antirheumatic drug,
• a dermatologic drug,
• an immunosuppressive agent,
• a metabolite,
• a carcinogenic agent,
• an anti-asthmatic drug,
• an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor,
• an anticoronaviral agent and
• a geroprotector.

SOURCE

https://pubchem.ncbi.nlm.nih.gov/compound/Ciclosporin