Innovative Genomics Initiative (IGI) 2016 CRISPR WORKSHOP: PRACTICAL ASPECTS OF PRECISION BIOLOGY, UC, Berkeley, July 11-15, 2016
Reporter: Aviva Lev-Ari, PhD, RN
2.2.7 Innovative Genomics Initiative (IGI) 2016 CRISPR WORKSHOP: PRACTICAL ASPECTS OF PRECISION BIOLOGY, UC, Berkeley, July 11-15, 2016, Volume 2 (Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS and BioInformatics, Simulations and the Genome Ontology), Part 2: CRISPR for Gene Editing and DNA Repair
Innovative Genomics Initiative
CRISPRWORKSHOP
PRACTICAL ASPECTS OF PRECISION BIOLOGY
July 11-15, 2016 – Berkeley, California
IGI’S 2016 CRISPR WORKSHOP: PRACTICAL ASPECTS OF PRECISION BIOLOGY
The IGI’s new summer CRISPR Workshop: Practical Aspects of Precision Biology on July 11-15, 2016, will give participants a unique opportunity to learn about CRISPR technology in a laboratory-focused environment. Distinguished presenters and pioneers in the field of genome engineering will present lectures on a variety of topics – including basic and enhanced CRISPR methods, cellular repair mechanisms, regulation of gene expression, bioinformatics, applications to various organisms, and bioethics – and a practical laboratory component will give participants hands-on experience under the guidance of current practitioners of CRISPR-Cas9 technology.
CRISPR Workshop: Practical Aspects of Precision Biology
Dates: July 11-15, 2016
Location: Berkeley, CA
APPLY NOW – Apply online February 16 through April 10, 2016
Workshop co-organizers Dana Carroll (Professor of Biochemistry at the University of Utah) andMartin Kampmann (Assistant Professor of Biochemistry & Biophysics at the University of California, San Francisco) are excited about expanding the scope of this year’s workshop to include a practical laboratory experience that will enable participants to engage in research techniques unique to CRISPR research. Dr. Carroll – who organized the IGI’s 2015 CRISPR Workshop: Routes to Designer Biology – made it a priority to incorporate a laboratory component in this year’s workshop: “We are excited to offer a laboratory experience, so students will see exactly how the CRISPR tools can be employed and appreciate their efficacy and simplicity.” Dr. Kampmann, an expert in the multiplexed screening aspect of gene editing research, is designing the workshop’s hands-on bioinformatics sessions, which will cover the basics of screen design and analysis – “Multiplexed targeting of genes using CRISPR-based technology is a transformative technology for uncovering gene function and cellular pathways.”
Confirmed presenters currently include: Dana Carroll (University of Utah), Jacob Corn (Innovative Genomics Initiative), Jennifer Doudna (Innovative Genomics Initiative; University of California, Berkeley; HHMI), Luke Gilbert (University of California, San Francisco), Hank Greely (Stanford University), Lin He (University of California, Berkeley), Max Horlbeck (University of California, San Francisco), Martin Kampmann (University of California, San Francisco), Randy Peterson (Harvard Medical School), Jonathan Weissman (University of California, San Francisco; HHMI).
This new workshop is designed for scientists in academia and industry who have limited experience with CRISPR technology and want to expand its use in their research, and applications from researchers at all levels – including graduate students, postdoctoral fellows and more senior researchers – will be accepted. Applications will be accepted online starting February 16, 2016, and the deadline to submit an application is April 10, 2016.
Application Process
https://innovativegenomics.org/crispr-workshop-2016/
IGI Videos
https://innovativegenomics.org/category/videos/
IGI HISTORY
The Innovative Genomics Initiative was established at the Li Ka Shing Center for Genomic Engineering in early 2014 through a generous gift from the Li Ka Shing Foundation. The gift also created an affiliated faculty chair, the Li Ka Shing Chancellor’s Chair in Biomedical and Health Sciences, which is currently held by executive director Jennifer Doudna. Li Ka-shing, a Hong Kong-based, self-made businessman and philanthropist, had also provided a cornerstone gift of US$40 million to establish the Li Ka Shing Center for Biomedical and Health Sciences, which opened its doors in 2012. The IGI main laboratories are housed in this state-of the-art building located on the campus of the University of California, Berkeley.
As of 2015, the IGI and its affiliated laboratories — at Bay Area universities including UC Berkeley, UCSF and Stanford University — are actively participating in collaborations with academic and industrial research partners worldwide in order to expand our understanding and promote the use and development of CRISPR-Cas9 technology. Support from private donors, foundations and industrial collaborations continues to support IGI science on a global scale.
SCHEDULED PRESENTERS
Find out more about our presenters and the topics they will cover below.

DANA CARROLL
University of Utah
Dr. Carroll pioneered the use of targetable nucleases for genome engineering. He will describe the development of the various nuclease platforms, discuss cellular DNA repair pathways and their influence on editing outcomes, and describe applications of CRISPR/Cas9 to Drosophila.
JACOB CORN
UC Berkeley
Dr. Corn, whose career has spanned both academia and industry, has developed new approaches for more efficient sequence knockin and knockout in human cells. He will discuss bioinformatic tools related to CRISPR technology.

JENNIFER DOUDNA
UC Berkeley
Dr. Doudna developed CRISPR-Cas9 genome editing tools and pioneered its use in a broad range of applications and laboratories worldwide. She will discuss these issues as well as structural and biochemical features of this system.

HANK GREELY
Stanford University
Dr. Greely specializes in the ethical, legal, and social implications of new biomedical technologies, particularly those related to neuroscience, genetics, or stem cell research. He will discuss ethical issues raised by CRISPR/Cas9 technology.
RANDALL T. PETERSON
Harvard Medical School
Dr. Peterson develops technologies for zebrafish research, including those related to high-throughput chemical screening and genome editing, and he will describe applications for genome editing in this model organism.

JONATHAN WEISSMAN
UC San Francisco
Dr. Weissman has led the use of nuclease-dead Cas9 for targeted uses in the genome. He will discuss applications to gene regulation and cellular imaging, as well as methods for multiplexing the CRISPR tools.
LUKE GILBERT
UC San Francisco
Dr. Gilbert is a Postdoctoral Scholar in Jonathan Weissman’s lab at UC San Francisco, and his research primarily focuses on applying CRISPR functional genomics to cancer biology. He will present the various uses of dCas9, CRISPRi and CRISPRa.
LIN HE
UC Berkeley
Dr. He’s research explores the roles of microRNAs in the oncogenic and tumor suppressor pathways. She will discuss CRISPR applications using mouse tumor models.
MARTIN KAMPMANN
UC San Francisco
Dr. Kampmann’s lab uses functional genomics technology to understand how human cells maintain their proteins in a functional and balanced state. He will discuss multiplexing with CRISPR.
MAX HORLBECK
UC San Francisco
Mr. Horlbeck is a graduate student in Jonathan Weissman’s lab at UC San Francisco, where he has developed tools for efficiently targeting CRISPRi and CRISPRa at genome scale. He will lead a practical session on bioinformatic tools related to CRISPR technology.


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Contact: Marsha Fenner, IGI Program Director (mwfenner@berkeley.edu)
SOURCE
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