The following post by Dr. Melvin Crasto on his site
contains a wonderful curation on a new TGF-beta antibody fresolimumab which inhibits multiple isoforms of TGF-beta and may have indications in cancer and inflammation. The curation includes informative diagrams on mechanism of action and TGF-beta signaling as well as pertinent PK/PD data.
Source: Fresolimumab
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