Lab Management: About The Doudna Lab, RNA Biology at UC Berkeley, HHMI

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Lab Management: About The Doudna Lab, RNA Biology at UC Berkeley, HHMI

January 21, 2016 by 2012pharmaceutical

Lab Management: About The Doudna Lab, RNA Biology at UC Berkeley, HHMI

Reporter: Aviva Lev-Ari, PhD, RN

See our Curation on the topic

Medical Interpretation of the Genomics Frontier – CRISPR – Cas9: Gene Editing Technology for New Therapeutics

Authors and Curators: Larry H Bernstein, MD, FCAP and Stephen J Williams, PhD and Curator: Aviva Lev-Ari, PhD, RN

2.1.5.24

2.1.5.24 Lab Management: About The Doudna Lab, RNA Biology at UC Berkeley, HHMI, Volume 2 (Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene Editing, NGS and BioInformatics, Simulations and the Genome Ontology), Part 2: CRISPR for Gene Editing and DNA Repair

Recommended Reading of an outstanding Science Writer:

‘On the same wavelength’

Jennifer Doudna credits her laboratory’s success
to someone she took a chance on 20 years ago

By Rajendrani Mukhopadyay

What is CRISPR?

It stands for: clustered regularly interspaced short palindromic repeats.

If you had asked Jennifer Doudna a few years ago about the gene-editing tool CRISPR, she would have described the research as “a pretty small effort in my lab, just a few people having fun checking it out.”

That was before a lightbulb went off, before Doudna and her postdoctoral fellow realized that the bacterial defense system could be exploited to fix faulty genes or bestow new functions on existing genes in all kinds of cells. The small effort in Doudna’s lab at the University of California, Berkeley, has since exploded into an international one, with laboratories in several continents furiously working on the gene-manipulation possibilities presented by the system. The method has received much attention in the mainstream press, including the New York Times, which described the adoption of CRISPR by researchers as a “scientific frenzy.”

CONTINUE TO READ

http://www.asbmb.org/asbmbtoday/201408/Features/Doudna/

About the author

raj_mukhopadhyay01_2 Rajendrani (Raj) Mukhopadhyay is the chief science correspondent for theAmerican Society for Biochemistry and Molecular Biology. Raj writes features and scientist profiles for ASBMB Today, the society’s membership magazine as well as posts for this blog. She also hosts G+ Hangouts on Air with ASBMB’s public outreach coordinator, Geoff Hunt. When not writing about the science that she finds fascinating, Raj pursues her other interests in food, music (she has a particular weakness for ’80s British pop) and books. Raj has a Ph.D. in biophysics and biochemistry from Johns Hopkins University. Follow her on Twitter!