Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Using CRISPR to investigate pancreatic cancer

Reporter: Aviva Lev-Ari, PhD, RN

Writing about pancreatic cancer always gives me a pang. My grandmother died from the disease over 30 years ago, but I still remember the anguish of her diagnosis and the years of chemotherapy and surgery she endured before her death. This disease is much more personal to me than many I cover.

Sourced through Scoop.it from: scopeblog.stanford.edu

Pancreatic cancer is very common and almost uniformly fatal. Human pancreatic cancers usually have many mutations in many different genes but we know very little about how most of them drive pancreatic cancer initiation, development, and progression. Recreating these cancer-causing mutations in cells of the mouse pancreas can generate tumors that look and behave very similarly to human pancreas cancer.

https://scopeblog.stanford.edu/2015/07/23/using-crispr-to-investigate-pancreatic-cancer/

See on Scoop.it – Cardiovascular Disease: PHARMACO-THERAPY