Reporter: Prabodh Kandala, PhD
compound found in cannabis may prove to be effective at helping stop the spread of breast cancer cells throughout the body.
The study, by scientists at the California Pacific Medical Center Research Institute, is raising hope that CBD, a compound found in Cannabis sativa, could be the first non-toxic agent to show promise in treating metastatic forms of breast cancer.
“Right now we have a limited range of options in treating aggressive forms of cancer,” says Sean D. McAllister, Ph.D., a cancer researcher at CPMCRI and the lead author of the study. “Those treatments, such as chemotherapy, can be effective but they can also be extremely toxic and difficult for patients. This compound offers the hope of a non-toxic therapy that could achieve the same results without any of the painful side effects.”
The researchers used CBD to inhibit the activity of a gene called Id-1, which is believed to be responsible for the aggressive spread of cancer cells throughout the body, away from the original tumor site.
“We know that Id-1 is a key regulator of the spread of breast cancer,” says Pierre-Yves Desprez, Ph.D., a cancer researcher at CPMCRI and the senior author of the study. “We also know that Id-1 has also been found at higher levels in other forms of cancer. So what is exciting about this study is that if CBD can inhibit Id-1 in breast cancer cells, then it may also prove effective at stopping the spread of cancer cells in other forms of the disease, such as colon and brain or prostate cancer.”
However, the researchers point out that while their findings are promising they are not a recommendation for people with breast cancer to smoke marijuana. They say it is highly unlikely that effective concentrations of CBD could be reached by smoking cannabis. And while CBD is not psychoactive it is still considered a Schedule 1 drug.
Ref:
http://www.sciencedaily.com/releases/2007/11/071123211703.htm
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as it is said smoking can’t be an alternative because of, as mentioned above, the fact that “it is highly unlikely that effective concentrations of CBD could be reached by smoking cannabis”.
Moreover, using a highly sensitive new test, scientists in Europe are reporting “convincing evidence” that marijuana smoke damages the genetic material DNA in ways that could increase the risk of cancer.
read more at the following link and the related articles there in:
http://www.sciencedaily.com/releases/2009/06/090615095940.htm
Amidst all the discussion of marijuana, a series of myths is often perpetuated.
Marijuana is sometimes characterized as being harmless and other times characterized as being very harmful.
Some express concern that increasing marijuana availability will increase its use, while others suggest that marijuana is already so widely available that increasing its availability will undercut the black market without increasing use.
Marijuana is touted as having widespread medicinal benefits by some, while others point to the notion that the evidence for marijuana’s role as a medicinal agent is very limited.
Some point to the notion that marijuana causes addiction, while others state that addiction to marijuana does not exist.
Ultimately, policy determinations on marijuana should rest on some OBJECTIVE VALUATION of its impact on individuals, as well as the public health. The purpose of the following most recent paper is to review the scientific literature …
https://litigation-essentials.lexisnexis.com/webcd/app?action=DocumentDisplay&crawlid=1&doctype=cite&docid=43+McGeorge+L.+Rev.+91&srctype=smi&srcid=3B15&key=a4836ac9da21b69291d362a63a822c41
Dr. Prabodh (and/ or anyone) if you have access to this full review article please summarize and share with us all. This is an important topic and readers will certainly appreciate our input.
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