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Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: Treating cancer like an infectious disease.   A group of scientists has proposed a new strategy for the treatment of early cancerous lesions and advanced metastatic disease, via the selective targeting of cancer stem cells (CSCs), a.k.a., tumor-initiating cells (TICs). They searched […]

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miR-361-regulated prohibitin inhibits mitochondrial fission and apoptosis and … Nature.com MiR-361 cardiac-specific transgenic mice represent elevated mitochondrial fission and myocardial infarction sizes upon myocardial ischemia injury. Source: news.google.com See on Scoop.it – Cardiovascular Disease: PHARMACO-THERAPY

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Powering the Cell: Mitochondria Reporter: Aviva Lev-Ari, PhD, RN VIEW VIDEO http://labroots.com/user/account-file/view-video/type/public-wall/id/826 Posted by: Robert Woodard Date: Thursday, Oct 30, 2014 Views: 1890 Link: https://www.youtube.com/watch?v=RrS2uROUjK4 Together Harvard University and XVIVO developed this 3D animation journey for Harvard’s undergraduate Molecular and Cellular Biology students about the microscopic world of mitochondria. The animation highlights the creation of Adenosine Triphosphate (ATP) — […]

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Larry H. Benstein, MD, FCAP, Gurator and writer https://pharmaceuticalintelligence.com/7/8/2014/Update on mitochondrial function, respiration, and associated disorders This is a condensed account of very recent published work on respiration and disturbed mitochondrail function.  We know that their is an equilibrium between respiration and autophagy in eukaryotic cells.  The Krebs Cycle produces 32 ATPs in oxidative phosphorylation, […]

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Essential MCU regulator (EMRE) in the Mitochondrial Calcium Uniporter (MCU) Complex Reviewer and Curator: Larry H. Bernstein, MD, FCAP    UPDSTED on 9/22/2018   J Biol Chem. 2016 Dec 2;291(49):25505-25515. Epub 2016 Oct 28. CRISPR/Cas9-mediated endogenous C-terminal Tagging of Trypanosoma cruzi Genes Reveals the Acidocalcisome Localization of the Inositol 1,4,5-Trisphosphate Receptor. Lander N1, Chiurillo MA2, Storey M3, Vercesi AE2, Docampo R4,3. […]

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Calcium Signaling, Cardiac Mitochondria and Metabolic Syndrome Larry H Bernstein: Author  and Reporter: Aviva Lev-Ari, PhD, RN Mitochondria, the cardiovascular system and metabolic syndrome Start date April 24, 2013 End date April 24, 2013 Venue London, UK / Kennedy Lecture Theatre, Institute of Child Health Location London, UK Topics – Mitochondrial ROS metabolism in the […]

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Mitochondrial Dysfunction and Cardiac Disorders Curator: Larry H Bernstein, MD, FACP This article is the THIRD in a four-article Series covering the topic of the Roles of the Mitochondria in Cardiovascular Diseases. They include the following; Mitochondria and Cardiovascular Disease: A Tribute to Richard Bing, Larry H Bernstein, MD, FACP https://pharmaceuticalintelligence.com/2013/04/14/chapter-5-mitochondria-and-cardiovascular-disease/ Mitochondrial Metabolism and Cardiac Function, Larry H […]

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Reversal of Cardiac mitochondrial dysfunction Curator: Larry H Bernstein, MD, FACP This article is the FOURTH in a four-article Series covering the topic of the Roles of the Mitochondria in Cardiovascular Diseases. They include the following; Mitochondria and Cardiovascular Disease: A Tribute to Richard Bing, Larry H Bernstein, MD, FACP https://pharmaceuticalintelligence.com/2013/04/14/chapter-5-mitochondria-and-cardiovascular-disease/ Mitochondrial Metabolism and Cardiac Function, Larry H […]

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Mitochondrial Metabolism and Cardiac Function Curator: Larry H Bernstein, MD, FACP This article is the SECOND in a four-article Series covering the topic of the Roles of the Mitochondria in Cardiovascular Diseases. They include the following; Mitochondria and Cardiovascular Disease: A Tribute to Richard Bing, Larry H Bernstein, MD, FACP https://pharmaceuticalintelligence.com/2013/04/14/chapter-5-mitochondria-and-cardiovascular-disease/ Mitochondrial Metabolism and Cardiac Function, Larry H […]

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Mitochondria and Cardiovascular Disease Curator: Larry H Bernstein, MD, FACP This article is the FIRST in a four-article Series covering the topic of the Roles of the Mitochondria in Cardiovascular Diseases. They include the following; Mitochondria and Cardiovascular Disease: A Tribute to Richard Bing, Larry H Bernstein, MD, FACP https://pharmaceuticalintelligence.com/2013/04/14/chapter-5-mitochondria-and-cardiovascular-disease/ Mitochondrial Metabolism and Cardiac Function, Larry H Bernstein, […]

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