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Search Results for 'metastasis'


Cancer Metastasis Author: Tilda Barliya PhD Metastasis, a complex process that involves the spread of tumor cells, accounts for more than 90%of cancer-related mortality (1,2). A metastatic tumor cell has a treacherous journey to go through: local invasion and intravasation survival in the circulation homing and extravasation into the parenchyma of distant organs adaptation to the new environment […]

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Targeting bone turnover by nature-derived agents for deriving effective treatment of PCa metastases Reporter: Ritu Saxena, Ph.D. Introduction and basis of research: Prostate Cancer (PCa) is a leading cause of cancer-related deaths in the men of United States. Metastasis development results in high mortality rate in prostate cancer patients and PCa frequently metastasizes to the […]

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Reporter: Prabodh Kandala, PhD A study from Massachusetts General Hospital (MGH) researchers suggests that specific populations of tumor cells have different roles in the process by which tumors make new copies of themselves and grow. In their report in the May 15 issue of Cancer Cell, researchers identify a tumor-propagating cell required for the growth of […]

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Engineered Bacteria used as Trojan Horse for Cancer Immunotherapy Reporter: Irina Robu, PhD Researchers are using synthetic biology— design and construction of new biological entities such as enzymes, genetic circuits, and cells or the redesign of existing biological systems—is changing medicine leading to innovative solution in molecular-based therapeutics. To address the issue of designing therapies that can induce a […]

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AI System Used to Detect Lung Cancer Reporter: Irina Robu, PhD Lung cancer is characterized by uncontrolled cell growth in tissues of the lung. The growth spreads beyond the lung by metastasis into nearby tissues. The most common symptoms are coughing (including coughing up blood), weight loss, shortness of breath, and chest pains. The two […]

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Featuring Computational and Systems Biology Program at Memorial Sloan Kettering Cancer Center, Sloan Kettering Institute (SKI), The Dana Pe’er Lab   Reporter: Aviva Lev-Ari, PhD, RN A lecture by Dana Pe’er is included, below in the eProceedings which I generated in Real Time on 6/14/2019 @MIT eProceeding 2019 Koch Institute Symposium – 18th Annual Cancer […]

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LIVE Day One – World Medical Innovation Forum ARTIFICIAL INTELLIGENCE, Boston, MA USA, Monday, April 8, 2019   http://www.worldmedicalinnovation.org   The Forum will focus on patient interactions across care settings, and the role technology and data can play in advancing knowledge discovery and care delivery. The agenda can be found here. https://worldmedicalinnovation.org/agenda/ Leaders in Pharmaceutical […]

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Celgene Triumphs in Legal Battle over Revlimid Patent: Curation of Patents, Litigations, and Impact on Drug Pricing Curator: Stephen J. Williams, PhD From Celgene REVLIMID® (lenalidomide) in combination with dexamethasone is indicated for the treatment of patients with multiple myeloma (MM). as maintenance therapy in patients with MM following autologous hematopoietic stem cell transplantation (auto-HSCT). […]

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Immunoediting can be a constant defense in the cancer landscape


Reporter and Curator: Dr. Sudipta Saha, Ph.D.   There are many considerations in the cancer immunoediting landscape of defense and regulation in the cancer hallmark biology. The cancer hallmark biology in concert with key controls of the HLA compatibility affinity mechanisms are pivotal in architecting a unique patient-centric therapeutic application. Selection of random immune products […]

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Lesson 5 Cell Signaling And Motility: Cytoskeleton & Actin: Curations and Articles of reference as supplemental information: #TUBiol3373 Curator: Stephen J. Williams, Ph.D. Cell motility or migration is an essential cellular process for a variety of biological events. In embryonic development, cells migrate to appropriate locations for the morphogenesis of tissues and organs. Cells need to migrate […]

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