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@Cleveland Clinic – Serial measurements of high-sensitivity C-reactive protein (hsCRP) post acute coronary syndrome (ACS) may help identify patients at higher risk for morbidity and mortality   Reporter: Aviva Lev-Ari, PhD, RN   Original Investigation March 6, 2019 Association of Initial and Serial C-Reactive Protein Levels With Adverse Cardiovascular Events and Death After Acute Coronary […]

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A Timeline of Dr. Gottlieb’s Tenure at the FDA: 2017-2019 Reporter: Stephen J. Williams, Ph.D.   From FiercePharma.com FDA chief Scott Gottlieb steps down, leaving pet projects behind by Eric Sagonowsky | Mar 5, 2019 3:50pm FDA Commissioner Scott Gottlieb was appointed by President Trump in 2017. (FDA) Not quite two years into his stewardship of the […]

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A new mechanism of action to attack in the treatment of coronary artery disease (CAD), Novartis developed Ilaris (canakinumab), a human monoclonal antibody targeting the interleukin-1beta innate immunity pathway Reporter: Aviva Lev-Ari, PhD, RN   Speaking at an ESC press briefing, Ridker said, “This is what personalized predictive medicine is all about.” Once a patient has […]

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Trends in HealthCare Economics: Average Out-of-Pocket Costs, non-Generics and Value-Based Pricing, Amgen’s Repatha and AstraZeneca’s Access to Healthcare Policies Reporter: Aviva Lev-Ari, PhD, RN   1.   AstraZeneca’s access to healthcare strategy is made up of three elements: Provide high-quality, effective and appropriate medicines to those who need them. Improve affordability, particularly among the growing middle […]

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Highlights – LIVE Day 2: World Medical Innovation Forum – CARDIOVASCULAR • MAY 1-3, 2017  BOSTON, MA • UNITED STATES   Leaders in Pharmaceutical Business Intelligence (LPBI) Group will cover the event in REAL TIME Aviva Lev-Ari, PhD, RN will be streaming live from the floor of the Westin Hotel in Boston on May 1-3, 2017 […]

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Regulatory MicroRNAs in Aberrant Cholesterol Transport and Metabolism Curator: Marzan Khan, B.Sc Aberrant levels of lipids and cholesterol accumulation in the body lead to cardiometabolic disorders such as atherosclerosis, one of the leading causes of death in the Western World(1). The physical manifestation of this condition is the build-up of plaque along the arterial endothelium […]

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LIVE 9/21 8AM to 2:40PM Targeting Cardio-Metabolic Diseases: A focus on Liver Fibrosis and NASH Targets at CHI’s 14th Discovery On Target, 9/19 – 9/22/2016, Westin Boston Waterfront, Boston http://www.discoveryontarget.com/ http://www.discoveryontarget.com/crispr-therapies/ #BostonDOT16 @BostonDOT   Nonalcoholic Steatohepatitis (NASH)   Leaders in Pharmaceutical Business Intelligence (LPBI) Group is a Media Partner of CHI for CHI’s 14th Annual Discovery on Target taking place […]

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LIVE 9/20 8AM to noon GENE THERAPIES BREAKTHROUGHS at CHI’s 14th Discovery On Target, 9/19 – 9/22/2016, Westin Boston Waterfront, Boston http://www.discoveryontarget.com/ http://www.discoveryontarget.com/crispr-therapies/ #BostonDOT16 @BostonDOT   Leaders in Pharmaceutical Business Intelligence (LPBI) Group is a Media Partner of CHI for CHI’s 14th Annual Discovery on Target taking place September 19 – 22, 2016 in Boston. In Attendance, streaming LIVE using […]

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Coronary Heart Disease Research: Sugar Industry influenced national conversation on heart disease – Adoption of Low Fat Diet vs Low Carbohydrates Diet Reporter: Aviva Lev-Ari, PhD, RN Public Health Outcome: Uncontrolled consumption of sugar prevailed 1965 – 2005 – role of sugar in CVD was played down while Consumption of fat become the diet factor […]

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Metabolic Genomics & Pharmaceutics 2015 http://www.amazon.com/dp/B012BB0ZF0   Author, Curator and Editor Larry H Bernstein, MD, FCAP Chief Scientific Officer Leaders in Pharmaceutical Business Intelligence Larry.bernstein@gmail.com Chapter 1: Metabolic Pathways 1.1            Carbohydrate Metabolism 1.2            Studies of Respiration Lead to Acetyl CoA 1.3            Pentose Shunt, Electron Transfer, Galactose, more Lipids in brief 1.4            The Multi-step Transfer of Phosphate Bond and Hydrogen Exchange Energy 1.5            Diabetes Mellitus […]

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