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Cancer Metastasis Author: Tilda Barliya PhD Metastasis, a complex process that involves the spread of tumor cells, accounts for more than 90%of cancer-related mortality (1,2). A metastatic tumor cell has a treacherous journey to go through: local invasion and intravasation survival in the circulation homing and extravasation into the parenchyma of distant organs adaptation to the new environment […]

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Targeting bone turnover by nature-derived agents for deriving effective treatment of PCa metastases Reporter: Ritu Saxena, Ph.D. Word Cloud By Danielle Smolyar Introduction and basis of research: Prostate Cancer (PCa) is a leading cause of cancer-related deaths in the men of United States. Metastasis development results in high mortality rate in prostate cancer patients and […]

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Reporter: Prabodh Kandala, PhD Word Cloud By Danielle Smolyar A study from Massachusetts General Hospital (MGH) researchers suggests that specific populations of tumor cells have different roles in the process by which tumors make new copies of themselves and grow. In their report in the May 15 issue of Cancer Cell, researchers identify a tumor-propagating cell […]

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From High-Throughput Assay to Systems Biology: New Tools for Drug Discovery Curator: Stephen J. Williams, PhD Marc W. Kirschner* Department of Systems BiologyHarvard Medical School Boston, Massachusetts 02115 With the new excitement about systems biology, there is understandable interest in a definition. This has proven somewhat difficult. Scientific fields, like spe­cies, arise by descent with […]

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Series D: e-Books on BioMedicine – Metabolomics, Immunology, Infectious Diseases, Reproductive Genomic Endocrinology Volume Four: Human Reproductive System, Genomic Endocrinology and Cancer Types Series Content Consultant: Larry H. Bernstein, MD, FCAP, Emeritus CSO, LPBI Group   http://www.amazon.com/dp/B08VTFWVKM   Available on Amazon.com since 2/2/2021 Product details ASIN : B08VTFWVKM Publisher : Leaders in Pharmaceutical Business Intelligence (LPBI) Group; 1st edition […]

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Papers citing PharmaceuticalIntelligence.com Reporter: Stephen J. Williams, PhD (10 papers, 5 peer reviewed, 2 web page, 2 teaching lectures, 1 preprint) Search from years 2012 – 2018 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777453/ Chin J Cancer. 2012 Oct; 31(10): 463–470. doi: 10.5732/cjc.012.10216 PMCID: PMC3777453 PMID: 22980418 Application of next-generation sequencing in clinical oncology to advance personalized treatment of cancer Yan-Fang Guan, Gai-Rui Li, Rong-Jiao Wang, Yu-Ting […]

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Data Architecture for Blockchain Deployment of Digital Assets: LPBI IP Asset Classes I,II,III,V Author: Aviva Lev-Ari, PhD, RN UPDATED on 6/26/2021 From: Erich Greenebaum <erich@prosperci.com> Date: Saturday, June 26, 2021 at 9:54 AM To: Aviva Lev-Ari <aviva.lev-ari@comcast.net>, Stephen Williams <sjwilliamspa@comcast.net>, John McCarthy <jfmccarthy2@gmail.com>, “George N. Gamota Jr” <gngamotajr@gmail.com> Cc: David DiPerri <david@prosperci.com> Subject: Blockchain Indexing […]

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WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN Introduction (From Cancer Volume 1): Cancer […]

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Systems Biology analysis of Transcription Networks, Artificial Intelligence, and High-End Computing Coming to Fruition in Personalized Oncology Curator: Stephen J. Williams, Ph.D. In the June 2020 issue of the journal Science, writer Roxanne Khamsi has an interesting article “Computing Cancer’s Weak Spots; An algorithm to unmask tumors’ molecular linchpins is tested in patients”[1], describing some […]

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Noam Steiner Tomer, Summer Internship, Research Assistant 1   8/11/2020   Aviva Lev-Ari, PhdD, RN, Founder & DIrector Leaders in Pharmaceutical Business Intelligence (LPBI) Group 83 Mandalay Road Newton, MA 02459     To Whom It May Concern:   It is my pleasure to write this letter of recommendation for Noam Steiner Tomer. Noam worked for […]

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