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Cancer Metastasis Author: Tilda Barliya PhD Metastasis, a complex process that involves the spread of tumor cells, accounts for more than 90%of cancer-related mortality (1,2). A metastatic tumor cell has a treacherous journey to go through: local invasion and intravasation survival in the circulation homing and extravasation into the parenchyma of distant organs adaptation to the new environment […]

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Targeting bone turnover by nature-derived agents for deriving effective treatment of PCa metastases Reporter: Ritu Saxena, Ph.D. Introduction and basis of research: Prostate Cancer (PCa) is a leading cause of cancer-related deaths in the men of United States. Metastasis development results in high mortality rate in prostate cancer patients and PCa frequently metastasizes to the […]

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Reporter: Prabodh Kandala, PhD A study from Massachusetts General Hospital (MGH) researchers suggests that specific populations of tumor cells have different roles in the process by which tumors make new copies of themselves and grow. In their report in the May 15 issue of Cancer Cell, researchers identify a tumor-propagating cell required for the growth of […]

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WordCloud Visualization of LPBI’s Top Sixteen Articles on CANCER in eight categories and by Views at All Time and their Research Categories in the Ontology of PharmaceuticalIntelligence.com Curator: Stephen J. Williams, PhD and WordCloud Producers: Daniel Menzin, Noam Steiner-Tomer, Zach Day, Ofer Markman, PhD and Aviva Lev-Ari, PhD, RN Introduction (From Cancer Volume 1): Cancer […]

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Systems Biology analysis of Transcription Networks, Artificial Intelligence, and High-End Computing Coming to Fruition in Personalized Oncology Curator: Stephen J. Williams, Ph.D. In the June 2020 issue of the journal Science, writer Roxanne Khamsi has an interesting article “Computing Cancer’s Weak Spots; An algorithm to unmask tumors’ molecular linchpins is tested in patients”[1], describing some […]

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Noam Steiner Tomer, Summer Internship, Research Assistant 1   8/11/2020   Aviva Lev-Ari, PhdD, RN, Founder & DIrector Leaders in Pharmaceutical Business Intelligence (LPBI) Group 83 Mandalay Road Newton, MA 02459     To Whom It May Concern:   It is my pleasure to write this letter of recommendation for Noam Steiner Tomer. Noam worked for […]

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Daniel Menzin, BSc BioMedical Engineering, expected, May 2021, Research Assistant 4, Core Applications Developer and Acting CTO https://pharmaceuticalintelligence.com/contributors-biographies/research-assistants/daniel-menzin-bsc-biomedical-engineering-expected-may-2021-research-assistant-4-core-applications-developer-and-acting-cto/   Letter of Recommendation for Daniel Menzin Written on 8/13/2020 by   Aviva Lev-Ari, PhD, RN Director & Founder https://lnkd.in/eEyn69r Leaders in Pharmaceutical Business Intelligence (LPBI) Group, Boston, NJ, New Delhi, Palo Alto, Philadelphia, Toronto, Newark, DE Editor-in-Chief […]

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Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 28, 2020 Session on Early Detection and ctDNA 1:35 – 3:55 PM Reporter: Stephen J. Williams, PhD Introduction Alberto Bardelli circulating tumor DNA has been around but with NGS now we can have more specificity in analyzing ctDNA interest lately in using liquid biopsy to […]

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Live Notes, Real Time Conference Coverage 2020 AACR Virtual Meeting April 27, 2020 Minisymposium on Drugging Undrugged Cancer Targets 1:30 pm – 5:00 pm SESSION VMS.ET01.01 – Drugging Undrugged Cancer Targets April 27, 2020, 1:30 PM – 3:30 PM Virtual Meeting: All Session Times Are U.S. EDT Session Type Virtual Minisymposium Track(s) Experimental and Molecular Therapeutics,Drug […]

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Cancer Genomics: Multiomic Analysis of Single Cells and Tumor Heterogeneity Curator: Stephen J. Williams, PhD   scTrio-seq identifies colon cancer lineages Single-cell multiomics sequencing and analyses of human colorectal cancer. Shuhui Bian et al. Science  30 Nov 2018:Vol. 362, Issue 6418, pp. 1060-1063 To better design treatments for cancer, it is important to understand the […]

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