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Search Results for 'genomics mutations'


Laboratory for Genomics Research (LGR) to be established by GSK ($67M investment in 5 years) at UC, Berkeley/UCSF to be lead by Prof. Jennifer Doudna focusing on immunology, oncology, and neuroscience disease-causing gene mutations and development of new technologies using CRISPR to accelerate new drug discovery   Reporter: Aviva Lev-Ari, PhD, RN   GlaxoSmithKline, UC’s […]

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Cancer Genomics: Multiomic Analysis of Single Cells and Tumor Heterogeneity Curator: Stephen J. Williams, PhD   scTrio-seq identifies colon cancer lineages Single-cell multiomics sequencing and analyses of human colorectal cancer. Shuhui Bian et al. Science  30 Nov 2018:Vol. 362, Issue 6418, pp. 1060-1063 To better design treatments for cancer, it is important to understand the […]

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Single-cell Genomics: Directions in Computational and Systems Biology – Contributions of Prof. Aviv Regev @Broad Institute of MIT and Harvard, Cochair, the Human Cell Atlas Organizing Committee with Sarah Teichmann of the Wellcome Trust Sanger Institute   Curator: Aviva Lev-Ari, PhD, RN   Dana Pe’er, PhD, now chair of computational and systems biology at the […]

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Emerging STAR in Molecular Biology, Synthetic Virology and Genomics: Clodagh C. O’Shea: ChromEMT – Visualizing 3D chromatin structure   Curator: Aviva Lev-Ari, PhD, RN   On 8/28/2017, I attend and covered in REAL TIME the CHI’s 5th Immune Oncology Summit – Oncolytic Virus Immunotherapy, August 28-29, 2017 Sheraton Boston Hotel | Boston, MA https://pharmaceuticalintelligence.com/2017/08/28/live-828-chis-5th-immune-oncology-summit-oncolytic-virus-immunotherapy-august-28-29-2017-sheraton-boston-hotel-boston-ma/   […]

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A novel 5-gene pancreatic adenocarcinoma classifier: Meta-analysis of transcriptome data – Clinical Genomics Research @BIDMC Curator: Tilda Barliya, PhD Analysis of  Bhasin et al paper and Literature search Table 1: 5-genes classifiers as biomarkers for PDAC: Gene symbol Gene name Subcellular localization ECT2 Epithelial cell transforming sequence 2 oncogene Nucleus, cytoplasm AHNAK2 AHNAKE nucleoprotein 2 […]

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Metabolic Genomics & Pharmaceutics 2015 http://www.amazon.com/dp/B012BB0ZF0   Author, Curator and Editor Larry H Bernstein, MD, FCAP Chief Scientific Officer Leaders in Pharmaceutical Business Intelligence Larry.bernstein@gmail.com Chapter 1: Metabolic Pathways 1.1            Carbohydrate Metabolism 1.2            Studies of Respiration Lead to Acetyl CoA 1.3            Pentose Shunt, Electron Transfer, Galactose, more Lipids in brief 1.4            The Multi-step Transfer of Phosphate Bond and Hydrogen Exchange Energy 1.5            Diabetes Mellitus […]

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Series C: e-Books on Cancer & Oncology Series C Content Consultant: Larry H. Bernstein, MD, FCAP   VOLUME ONE  Cancer Biology and Genomics for Disease Diagnosis 2015 http://www.amazon.com/dp/B013RVYR2K Stephen J. Williams, PhD, Senior Editor sjwilliamspa@comcast.net Tilda Barliya, PhD, Editor tildabarliya@gmail.com Ritu Saxena, PhD, Editor ritu.uab@gmail.com Leaders in Pharmaceutical Business Intelligence  Part I Historical Perspective of Cancer […]

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Series B: Frontiers in Genomics Research Content Consultant: Larry H Bernstein, MD, FCAP Genomics Orientations for Personalized Medicine Volume One http://www.amazon.com/dp/B018DHBUO6 electronic Table of Contents Chapter 1 1.1 Advances in the Understanding of the Human Genome The Initiation and Growth of Molecular Biology and Genomics – Part I 1.2 CRACKING THE CODE OF HUMAN LIFE: Milestones […]

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DISCUSSION – Genomics-driven personalized medicine for Pancreatic Cancer Reporter: Aviva Lev-Ari, PhD, RN [bold face added, ALA] Integrated Patient-Derived Models Delineate Individualized Therapeutic Vulnerabilities of Pancreatic Cancer –>>> Personalized Tumor Models Could Help Identify Combination Therapies for Hard-to-Treat Cancers   Original article Pancreatic Cancer – Genomics-driven personalized medicine   PDAC has a particularly poor prognosis, […]

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Tumor Genome Profiling Technology and Genomics Research Services from Mount Sinai Services: Offering of Personalis Reporter: Aviva Lev-Ari, PhD, RN Personalis, Mount Sinai Services to Offer Tumor Genome Profiling Technology Personalis announced today that it has signed a letter of intent to offer its next-generation tumor sequencing and interpretation technology in Canada through a collaboration […]

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