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Search Results for 'cancer sequencing'

Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Posted in Cancer - General, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Genomics, Genomic Testing: Methodology for Diagnosis, Next Generation Sequencing (NGS), Single Cell Genomics, tagged , , , , , , , , , , , , on August 14, 2019| Leave a Comment »


Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line Reporter: Stephen J. Williams, PhD In a Genome Research report by Marie Nattestad et al. [1], the SK-BR-3 breast cancer cell line was sequenced using a long read single molecule sequencing protocol in order to develop one […]

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First Cost-Effectiveness Study of Multi-Gene Panel Sequencing in Advanced Non-Small Cell Lung Cancer Shows Moderate Cost-Effectiveness, Exposes Crucial Practice Gap

Posted in Cancer and Current Therapeutics, Cancer Informatics, Genetics & Innovations in Treatment, Genetics & Pharmaceutical, Genome Biology, Genomic Expression, Genomic Testing: Methodology for Diagnosis, Genomics Pharmacy, Mutagenesis, Personalized and Precision Medicine & Genomic Research on June 27, 2019| Leave a Comment »


First Cost-Effectiveness Study of Multi-Gene Panel Sequencing in Advanced Non-Small Cell Lung Cancer Shows Moderate Cost-Effectiveness, Exposes Crucial Practice Gap WASHINGTON (June 27, 2019) — The results of the first economic modeling study to estimate the cost-effectiveness of “multi-gene panel sequencing” (MGPS) as compared to standard-of-care, single-gene tests for patients with advanced non-small cell lung […]

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Second Annual Single-Cell Sequencing of Cancer Rountable August 20,21, 2014 Washington DC

Posted in Bio Instrumentation in Experimental Life Sciences Research, CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Signaling & Cell Circuits, Disease Biology, Small Molecules in Development of Therapeutic Drugs, Personalized and Precision Medicine & Genomic Research, RNA Biology, Cancer and Therapeutics, Scientific & Biotech Conferences: Press Coverage, tagged , , , , , , , , , , , , , on June 19, 2014| Leave a Comment »


CSHL, UCLA & Einstein to Lead Roundtable Discussions on Single-Cell Sequencing Interactive discussions on three of the key questions researchers are facing when considering single-cell analysis will be held on the second day of the Single-Cell Sequencing Conference at Next Generation Dx Summit, taking place August 20-21, 2014 in Washington, DC. For full program details […]

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US Personalized Cancer Genome Sequencing Market Outlook 2018 –

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Genome Biology, Genomic Expression on May 5, 2014| Leave a Comment »


US Personalized Cancer Genome Sequencing Market Outlook 2018 Reporter: Aviva lev-Ari, PhD, RN Published: March 2014 | Pages: 65 | Format: PDF  The whole genome sequencing technology, over the past decade, has developed at an unprecedented rate. There has been a rapid progression from targeted gene sequencing to targeted whole genome sequencing coupled with bioinformatics […]

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Salivary Gland Cancer – Adenoid Cystic Carcinoma: Mutation Patterns: Exome- and Genome-Sequencing @ Memorial Sloan-Kettering Cancer Center

Posted in Biological Networks, Gene Regulation and Evolution, CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Signaling & Cell Circuits, Chemical Biology and its relations to Metabolic Disease, Chemical Genetics, Computational Biology/Systems and Bioinformatics, Disease Biology, Small Molecules in Development of Therapeutic Drugs, Genome Biology, Genomic Testing: Methodology for Diagnosis, Metabolomics, Molecular Genetics & Pharmaceutical, Personalized and Precision Medicine & Genomic Research, Regulated Clinical Trials: Design, Methods, Components and IRB related issues, tagged , , , , on May 20, 2013| 3 Comments »


Reporter: Aviva Lev-Ari, PhD, RN   Researchers Report on Mutational Patterns in Adenoid Cystic Carcinoma May 20, 2013 By a GenomeWeb staff reporter NEW YORK (GenomeWeb News) – A Memorial Sloan-Kettering Cancer Center-led team has taken an exome- and genome-sequencing centered look at the mutations that may be found in the salivary gland cancer adenoid cystic […]

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Issues in Personalized Medicine in Cancer: Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Posted in Biological Networks, Gene Regulation and Evolution, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Prevention: Research & Programs, Cell Biology, Signaling & Cell Circuits, Chemical Biology and its relations to Metabolic Disease, Computational Biology/Systems and Bioinformatics, Disease Biology, Small Molecules in Development of Therapeutic Drugs, Genome Biology, Genomic Testing: Methodology for Diagnosis, Health Economics and Outcomes Research, Molecular Genetics & Pharmaceutical, Personalized and Precision Medicine & Genomic Research, tagged , , , , , , , , , , , , , , , , , , , , on April 10, 2013| 16 Comments »


Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing[1] Curator and Reporter: Stephen J. Williams, Ph.D. Genomic instability is considered a hallmark and necessary for generating the mutations which drive tumorigenesis. Multiple studies had suggested that there may be multiple driver mutations and a plethora of passenger mutations driving a single tumor.  This diversity of […]

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LEADERS in Genome Sequencing of Genetic Mutations for Therapeutic Drug Selection in Cancer Personalized Treatment: Part 2

Posted in Biomarkers & Medical Diagnostics, Chemical Genetics, Computational Biology/Systems and Bioinformatics, Disease Biology, Small Molecules in Development of Therapeutic Drugs, Drug Delivery Platform Technology, Genome Biology, Genomic Testing: Methodology for Diagnosis, Interviews with Scientific Leaders, Medical and Population Genetics, Metabolomics, Molecular Genetics & Pharmaceutical, Personalized and Precision Medicine & Genomic Research, Pharmaceutical R&D Investment, Pharmacogenomics, Population Health Management, Genetics & Pharmaceutical, Proteomics, Reproductive Andrology, Embryology, Genomic Endocrinology, Preimplantation Genetic Diagnosis and Reproductive Genomics, Stem Cells for Regenerative Medicine, Technology Transfer: Biotech and Pharmaceutical, tagged , , , , , , , , on January 13, 2013| 19 Comments »


Curator:  Aviva Lev-Ari, PhD,RN Cancer Diagnostics by Genomic Sequencing: ‘No’ to Sequencing Patient’s DNA, ‘No’ to Sequencing Patient’s Tumor, ‘Yes’ to focus on Gene Mutation Aberration & Analysis of Gene Abnormalities How to Tailor Cancer Therapy to the particular Genetics of a patient’s Cancer THIS IS A SERIES OF FOUR POINTS OF VIEW IN SUPPORT […]

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Inspiration From Dr. Maureen Cronin’s Achievements in Applying Genomic Sequencing to Cancer Diagnostics

Posted in Interviews with Scientific Leaders, Scientist: Career considerations, tagged , on January 10, 2013| 13 Comments »


Reporter: Aviva Lev-Ari, PhD, RN presented from our Research Category on  Interviews with Scientific Leaders   Inspiration From Dr. Maureen Cronin’s Achievements in Applying Genomic Sequencing to Cancer Diagnostics Posted by: Patrick Terry on October 18, 2011 Related to: Healthcare Trends, In Vitro Diagnostics     The Tale of Two Tests “It was the best of times, it was the […]

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Deep Learning extracts Histopathological Patterns and accurately discriminates 28 Cancer and 14 Normal Tissue Types: Pan-cancer Computational Histopathology Analysis

Posted in Artificial Intelligence Applications in Health Care, Artificial Intelligence in CANCER, Artificial Intelligence in Health Care - Tools & Innovations, Artificial Intelligence in Medicine - Application for Diagnosis, CANCER BIOLOGY & Innovations in Cancer Therapy, Computational Biology/Systems and Bioinformatics, Computational Histopathology, Deep Learning in Pathology, Genome Biology, Meta-analysis of transcriptome data on October 28, 2019| Leave a Comment »


Deep Learning extracts Histopathological Patterns and accurately discriminates 28 Cancer and 14 Normal Tissue Types: Pan-cancer Computational Histopathology Analysis Reporter: Aviva Lev-Ari, PhD, RN Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis Yu Fu1, Alexander W Jung1, Ramon Viñas Torne1, Santiago Gonzalez1,2, Harald Vöhringer1, Mercedes Jimenez-Linan3, Luiza Moore3,4, and Moritz Gerstung#1,5 # to whom […]

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Cancer Genomics: Multiomic Analysis of Single Cells and Tumor Heterogeneity

Posted in AI in healthcare, Anticancer Resistance, Bio-MEMS, Biological Networks, Biological Networks, Gene Regulation and Evolution, Cancer - General, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Informatics, Cell Biology, Cell Biology, Signaling & Cell Circuits, Gene Regulation, Genome Biology, Methylation, Single Cell Genomics, Single-cell sequencing, tagged , , , , , , on October 15, 2019| Leave a Comment »


Cancer Genomics: Multiomic Analysis of Single Cells and Tumor Heterogeneity Curator: Stephen J. Williams, PhD   scTrio-seq identifies colon cancer lineages Single-cell multiomics sequencing and analyses of human colorectal cancer. Shuhui Bian et al. Science  30 Nov 2018:Vol. 362, Issue 6418, pp. 1060-1063 To better design treatments for cancer, it is important to understand the […]

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