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New Etiology for COVID-19: Death results from Immune-Mediation (virus-independent immunopathology: lung and reticuloendothelial system) vs Pathogen-Mediation causing Organ Dysfunction & Hyper-Inflammation – Immunomodulatory Therapeutic Approaches (dexamethasone)

Posted in COVID-19, Immune-Mediation (independent immunopathology: lung and reticuloendothelial system), Population Health Management, Genetics & Pharmaceutical, SARS-CoV-2, Serology tests for coronavirus antibodies, Treatment Protocols for COVID-19, Virus Infective Acute Respiratory Syndrome: SARS-CoV on July 12, 2020| Leave a Comment »


New Etiology for COVID-19: Death results from Immune-Mediation (virus-independent immunopathology: lung and reticuloendothelial system) vs Pathogen-Mediation causing Organ Dysfunction & Hyper-Inflammation – Immunomodulatory Therapeutic Approaches (dexamethasone) Curators: Stephen J. Williams and Aviva Lev-Ari, PhD, RN   State of Science on 7/21/2020 New Etiology for COVID-19: Death results from Immune-Mediation (virus-independent immunopathology: lung and reticuloendothelial system) […]

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The Relevance of Glycans in the Viral Pathology of COVID-19

Posted in Biological Engineering, Glycobiology: Biopharmaceutical Production, Microbiology, Virology, tagged , on March 23, 2020| 8 Comments »


The Relevance of Glycans in the Viral Pathology of COVID-19   Reporter: Ofer Markman, PhD   While we are constantly cautioning people from putting too high validity to the results seen in the bellow mentioned Study,  The ABO blood groups are a result of various and different glycans on the surfaces of red blood cells […]

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New Explanations for Evolution of Alzheimer’s Disease (AD): The Association between Brain neuroanatomy,  Brain Pathology and AD Biomarkers – Orientation and Attention are affected by the roles of Temporo-parietal junction (TPJ), Ventral attentional control network, Theory of mind, Inferior parietal cortex

Posted in Alzheimer's Disease, Etiology on February 27, 2020| 1 Comment »


New Explanations for Evolution of Alzheimer’s Disease (AD): The Association between Brain neuroanatomy,  Brain Pathology and AD Biomarkers – Orientation and Attention are affected by the roles of Temporo-parietal junction (TPJ), Ventral attentional control network, Theory of mind, Inferior parietal cortex   Reporter and Curator: Aviva Lev-Ari, PhD, RN   UPDATED on 3/2/2020 Blood test […]

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Deep Learning extracts Histopathological Patterns and accurately discriminates 28 Cancer and 14 Normal Tissue Types: Pan-cancer Computational Histopathology Analysis

Posted in Artificial Intelligence Applications in Health Care, Artificial Intelligence in CANCER, Artificial Intelligence in Health Care - Tools & Innovations, Artificial Intelligence in Medicine - Application for Diagnosis, CANCER BIOLOGY & Innovations in Cancer Therapy, Computational Biology/Systems and Bioinformatics, Computational Histopathology, Deep Learning in Pathology, Genome Biology, Meta-analysis of transcriptome data on October 28, 2019| Leave a Comment »


Deep Learning extracts Histopathological Patterns and accurately discriminates 28 Cancer and 14 Normal Tissue Types: Pan-cancer Computational Histopathology Analysis Reporter: Aviva Lev-Ari, PhD, RN 3.5.1.1   Deep Learning extracts Histopathological Patterns and accurately discriminates 28 Cancer and 14 Normal Tissue Types: Pan-cancer Computational Histopathology Analysis, Volume 2 (Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene […]

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CancerBase.org – The Global HUB for Diagnoses, Genomes, Pathology Images: A Real-time Diagnosis and Therapy Mapping Service for Cancer Patients – Anonymized Medical Records accessible to

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Computational Biology/Systems and Bioinformatics, Genetics & Innovations in Treatment, Genetics & Pharmaceutical, Genome Biology, Imaging-based Cancer Patient Management on July 28, 2016| Leave a Comment »


CancerBase.org – The Global HUB for Diagnoses, Genomes, Pathology Images: A Real-time Diagnosis and Therapy Mapping Service for Cancer Patients – Anonymized Medical Records accessible to anyone on Earth Reporter: Aviva Lev-Ari, PhD, RN   UPDATED on 10/29/2019 Pan-cancer computational histopathology reveals mutations, tumor composition and prognosis Yu Fu1, Alexander W Jung1, Ramon Viñas Torne1, […]

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Pathology Reports

Posted in Cancer - General, Cancer and Current Therapeutics, Clinical & Translational, Clinical Diagnostics, Curation, tagged , , on February 20, 2016| Leave a Comment »


Pathology Reports Larry H. Bernstein, MD, FCAP, Curator LPBI   Complete Pathology Reports and Clinical Decision Making Posted by Michael Doyle on Jan 15, 2015   http://www.softworksgroup.com/blog/complete-pathology-reports (Synoptic Reporting) Pathology reports provide care teams with crucial diagnostic and prognostic data. For population-level research and quality assurance initiatives, it’s important that reports are consistently complete. But report […]

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Identifying Another Piece in the Parkinson’s Disease Pathology Puzzle

Posted in Biomarkers & Medical Diagnostics, Uncategorized, tagged on February 2, 2016| Leave a Comment »


Press release on January 29,2016 International Consortium Identifies and Validates Cellular Role of Priority Parkinson’s Disease Drug Target, LRRK2 Kinase An international public-private consortium MARTINSRIED, GERMANY; DUNDEE, UNITED KINGDOM; NEW YORK, has identified and validated a cellular role of a primary Parkinson’s disease drug target, LRRK2 kinase. This finding was published in the online open […]

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Pathology Insights

Posted in Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Screening, Clinical Diagnostics, Clinical Genomics, Curation, Genomic Testing: Methodology for Diagnosis, Human Immune System in Health and in Disease, Innovations, Lung and pulmonology, Personalized and Precision Medicine & Genomic Research, RNA Biology, Cancer and Therapeutics, tagged , , , , , on October 28, 2015| Leave a Comment »


Pathology Insights Larry H Bernstein, MD, FCAP, Curator LPBI   Translational Lung Cancer Research Predicting the Prognosis of Lung Cancer: The Evolution of Tumor, Node and Metastasis in the Molecular Age—Challenges and Opportunities Ramón Rami-Porta; Hisao Asamura; Peter Goldstraw Transl Lung Cancer Res. 2015;4(4):415-423. http://www.medscape.com/viewarticle/852315   Abstract and Introduction Origin and Evolution of the TNM Classification […]

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Topics in Pathology

Posted in Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Clinical & Translational, Genomic Expression, tagged , , , , , on October 1, 2015| Leave a Comment »


Topics in Pathology Larry H Bernstein, MD, FCAP, Curator LPBI Special Issues from Medscape Pathology Journal of Clinical Pathology Hospital Autopsy: Endangered or Extinct? Angus Turnbull; Michael Osborn; Nick Nicholas Disclosures J Clin Pathol. 2015;68(8):601-604. Abstract Aim To determine the hospital autopsy rate for the UK in 2013. Methods A study of data from a ‘Freedom of Information’ […]

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Outstanding Achievement in Pathology

Posted in BioIT: BioInformatics, Biological Networks, Biomarkers & Medical Diagnostics, Bone Disease and Musculoskeletal Disease, Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Screening, Cardiac and Cardiovascular Surgical Procedures, Cell Biology, Cerebrovascular and Neurodegenerative Diseases, Peripheral Arterial Disease & Peripheral Vascular Surgery, tagged , , , , , , , on September 26, 2015| Leave a Comment »


Outstanding Achievement in Pathology Curator: Larry H Bernstein, MD, FCAP   Olympus America Honors Outstanding Pathologists During First Annual “Unsung Heroes” Awards Melville, Ny—Tracey Corey Handy, M.D., Chief Medical Examiner of Kentucky, and Matthew Zarka, M.D., affiliated with the University of Vermont and the Fletcher Allen Health Center, were recognized as the 1999 winners of […]

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