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HDL oxidation in type 2 diabetic patients Larry H. Bernstein, MD, FCAP, Curator LPBI         High-density lipoprotein oxidation in type 2 diabetic patients and young patients with premature myocardial infarction G. Sartorea, R. Seragliab, S. Burlinaa, , , A. Bolisa, R. Marina, E. Manzatoa, E. Ragazzic, P. Traldib, A. Lapollaa Nutr Metab Cardiovasc Dis April 2015; 25(4): 418–425       http://dx.doi.org:/10.1016/j.numecd.2014.12.004 […]

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In Eli Lilly’s Pipeline: DISCONTINUING Evacetrapib, a CETP inhibitor that’s meant to boost HDL Reporter: Aviva Lev-Ari, PhD, RN   Pharma giant Eli Lilly’s pipeline lost a star contender on Monday when the company disclosed that it would be discontinuing trials for evacetrapib, a lead CVD drug candidate that the Indianapolis-based pharma believed would eventually garner […]

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HDL-C: Target of Therapy – Steven E. Nissen, MD, MACC, Cleveland Clinic vs Peter Libby, MD, BWH Reporter: Aviva Lev-Ari, PhD, RN   UPDATED on 7/29/2018 HDL-C: Is It Time to Stop Calling It the ‘Good’ Cholesterol? – Medscape – Jul 27, 2018. What triggers dysfunctional HDL? It has long been known that such conditions as acute coronary syndrome,[15] diabetes, or systemic […]

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LDL, HDL, TG, ApoA1 and ApoB: Genetic Loci Associated With Plasma Concentration of these Biomarkers – A Genome-Wide Analysis With Replication Reporter: Aviva Lev-Ari, PhD, RN Genetic Loci Associated With Plasma Concentration of Low-Density Lipoprotein Cholesterol, High-Density Lipoprotein Cholesterol, Triglycerides, Apolipoprotein A1, and Apolipoprotein B Among 6382 White Women in Genome-Wide Analysis With Replication Daniel […]

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Curator: Aviva Lev-Ari, PhD, RN Evidence of HDL Modulation of eNOS in Humans  Whereas the functional link between HDL and eNOS has been appreciated only recently, the relationship between HDL and endothelium-dependent vasodilation has been known for some time. In studies of coronary vasomotor responses to acetylcholine, it was noted in 1994 that patients with […]

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If you are hoping to lower your risk of a heart attack simply by raising your levels of “good” cholesterol—high-density lipoproteins (HDLs)—you may be disappointed. Although epidemiological studies point to HDLs as protective against heart disease, a new genetic analysis presented at the meeting shows that while high HDL might correlate with a healthier heart, it’s […]

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Noam Steiner Tomer, Summer Internship, Research Assistant 1 7/31/20 Genomics Articles Word Clouds Article Name w/ Live Link All Time Views Categories of Research Big Data in Genomic Medicine 695 Bio Instrumentation in Experimental Life Sciences Research, Chemical Biology and its relations to Metabolic Disease, Chemical Genetics, Computational Biology/Systems and Bioinformatics, Genome Biology, Genomic Testing: Methodology for Diagnosis, Molecular Genetics & Pharmaceutical, Personalized […]

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Disentangling molecular alterations from water-content changes in the aging human brain using quantitative MRI Reporter: Dror Nir, PhD   Authors’ list: Shir Filo, Oshrat Shtangel, Noga Salamon, Adi Kol, Batsheva Weisinger, Sagiv Shifman & Aviv A. Mezer Published in: Nature Communications volume 10, Article number: 3403 (2019) Abstract It is an open question whether aging-related […]

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Biotechnology & Pharma: 2018 Investment Budget in R&D – Top Ten Companies, Top R&D% AZ, Merck, BMS, Eli Lilly Reporter: Aviva Lev-Ari, PhD, RN   AstraZeneca Budget 5,932,000,000 R&D 5,932,000,000 27.0% Merck            Budget 9,750,000,000 R&D 9,750,000,000 23.0% BMS               Budget 6,345,000,000 R&D 6,345,000,000 23.0% Eli […]

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2020 Jessie Stevenson Kovalenko Medal for Outstanding Research in the Medical Sciences – Call for Nominations   Reporter: Aviva Lev-Ari, PhD, RN   SOURCE http://www.nasonline.org/programs/awards/kovalenko-medal.html PROGRAMS Awards 2020 Awards How to Nominate Alphabetical Listing Awards by Field National Academies Awards for Communicating Science Connect with Awards Cultural Programs Distinctive Voices Human Gene Editing Initiative Kavli Frontiers […]

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