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Will the Supreme Court accept a UC Berkeley Appeal of the Sep. 10th, US Court of Appeals for the Federal Circuit decision to uphold the patent filed by the Broad Institute on CRISPR/Cas9 gene editing? Reporter: Aviva Lev-Ari, PhD, RN   On 2018, Sep. 10th, the US Court of Appeals for the Federal Circuit agreed to uphold the patent filed […]

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Sickle Cell and Beta Thalassemia chosen for first human trial of the gene editing technology, CRISPR by sponsoring companies CRISPR Therapeutics and Vertex Pharmaceuticals, trial at a single site in Germany,   Reporter: Aviva Lev-Ari, PhD, RN UPDATED on 9/13/2018   September 13, 2018 NIH launches initiative to accelerate genetic therapies to cure sickle cell disease […]

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Reporter and Curator: Dr. Sudipta Saha, Ph.D.   Researchers have embraced CRISPR gene-editing as a method for altering genomes, but some have reported that unwanted DNA changes may slip by undetected. The tool can cause large DNA deletions and rearrangements near its target site on the genome. Such alterations can confuse the interpretation of experimental […]

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On June 12, 2018 – Berkeley was granted a patent on using CRISPR/Cas9 to edit single-stranded RNA. On June 19, 2018 – Berkeley was granted a second patent, covering the use of CRISPR-Cas9 gene editing with formats that will be particularly useful in developing human therapeutics and improvements in food security. Reporter and Curator: Aviva Lev-Ari, PhD, RN […]

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Appellate Brief Seeking Reversal of U.S. Patent Board Decision on CRISPR/Cas9 Gene Editing Reporter: Aviva Lev-Ari, PhD, RN [Boldface added] Appeal seeks reversal of Patent Trial and Appeal Board decision terminating interference without determining priority of inventorship of CRISPR/Cas9 gene editing Brief asserts that the Board failed to properly apply controlling U.S. Supreme Court and […]

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Innovations on the CRISPR System for Gene Editing: (1) Cryo-electron microscopy-based visualization of Cas3 Enzyme Cleavage (2) New tool testing an entire genome against a CRISPR molecule to predict potential errors and interactions Curator and Reporter: Aviva Lev-Ari, PhD, RN   Boom in human gene editing as 20 CRISPR trials gear up A pioneering CRISPR […]

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GENE EDITING: Promises and Challenges: HSPH and NBC News Digital, Friday, May 19, 2017  Live webcast: 12:30-1:30pm ET Reporter: Aviva Lev-Ari, PhD, RN THE ANDELOT SERIES ON CURRENT SCIENCE CONTROVERSIES GENE EDITING: Promises and Challenges  Presented jointly with NBC News Digital Friday, May 19, 2017 Live webcast: 12:30-1:30pm ET ForumHSPH.org   In labs and in clinical […]

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Gene Editing Consortium of Biotech Companies: CRISPR Therapeutics $CRSP, Intellia Therapeutics $NTLA, Caribou Biosciences, ERS Genomics, UC, Berkeley (Doudna’s IP) and University of Vienna (Charpentier’s IP), is appealing the decision ruled that there was no interference between the two sides, to the U.S. Court of Appeals for the Federal Circuit, targeting patents from The Broad Institute. […]

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FEBS Journal Special Issue on CRISPR/Cas9 Gene Editing by news.wiley.com Reporter: Aviva Lev-Ari, PhD, RN   FEBS Journal Special Issue on CRISPR FEBS Journal Special Issue on CRISPR/Cas9 The FEBS Journal The discovery of CRISPR in archaea and bacteria The FEBS Journal Design, execution, and analysis of pooled in vitro CRISPR/Cas9 screens The FEBS Journal […]

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LIVE – The CRISPR/Cas9 Revolution and Gene Editing: 2016 WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM Reporter: Aviva Lev-Ari, PhD, RN Each year the recipient(s) of the Warren Alpert Foundation Prize are recognized at a scientific symposium hosted by Harvard Medical School. OCTOBER 6, 2016 – 1:30PM TO 5:30PM 2016 WARREN ALPERT FOUNDATION PRIZE SYMPOSIUM The CRISPR/Cas9 […]

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