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Search Results for 'Gene Editing'


Optimization of CRISPR Gene Editing with Gold Nanoparticles Reporter: Irina Robu, PhD The CRISPR-Cas9 gene editing system has been welcomed as a hopeful solution to a range of genetic diseases, but the expertise has proven hard to deliver into cells. One plan is to open the cell membrane using an electric shock, but that can […]

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Breakthrough in Gene Editing CRISPR–Cas systems: First example of a fully programmable, RNA-guided integrase and lays the foundation for genomic manipulations that obviate the requirements for double-strand breaks and homology-directed repair.   Reporter: Aviva Lev-Ari, PhD, RN   CRISPR alternatives for editing genes without cutting: CRISPR 12, 12a, 13, 14 – Alternative Techniques to CRISPR/Cas9 […]

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Alter the Code of Life – Technologies for Gene Editing from MammothBiosciences, San Francisco, CA   Reporter: Aviva Lev-Ari, PhD, RN UPDATED on 6/13/2019 Each CRISPR Cas protein offers different strengths in various applications because of factors like speed, precision, and cost, the company’s founders believe. Adding Cas14 to its arsenal allows Mammoth to target […]

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Will the Supreme Court accept a UC Berkeley Appeal of the Sep. 10th, US Court of Appeals for the Federal Circuit decision to uphold the patent filed by the Broad Institute on CRISPR/Cas9 gene editing? Reporter: Aviva Lev-Ari, PhD, RN   UPDATED on June 6, 2019 Several companies were founded on the initial CRISPR IP rights granted […]

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Sickle Cell and Beta Thalassemia chosen for first human trial of the gene editing technology, CRISPR by sponsoring companies CRISPR Therapeutics and Vertex Pharmaceuticals, trial at a single site in Germany,   Reporter: Aviva Lev-Ari, PhD, RN UPDATED on 3/09/2019 CRISPR Therapeutics share up on announcement of first dosing in the joint Vertex sponsored trial for […]

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Reporter and Curator: Dr. Sudipta Saha, Ph.D.   Researchers have embraced CRISPR gene-editing as a method for altering genomes, but some have reported that unwanted DNA changes may slip by undetected. The tool can cause large DNA deletions and rearrangements near its target site on the genome. Such alterations can confuse the interpretation of experimental […]

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On June 12, 2018 – Berkeley was granted a patent on using CRISPR/Cas9 to edit single-stranded RNA. On June 19, 2018 – Berkeley was granted a second patent, covering the use of CRISPR-Cas9 gene editing with formats that will be particularly useful in developing human therapeutics and improvements in food security. Reporter and Curator: Aviva Lev-Ari, PhD, RN […]

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Appellate Brief Seeking Reversal of U.S. Patent Board Decision on CRISPR/Cas9 Gene Editing Reporter: Aviva Lev-Ari, PhD, RN [Boldface added] Appeal seeks reversal of Patent Trial and Appeal Board decision terminating interference without determining priority of inventorship of CRISPR/Cas9 gene editing Brief asserts that the Board failed to properly apply controlling U.S. Supreme Court and […]

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Innovations on the CRISPR System for Gene Editing: (1) Cryo-electron microscopy-based visualization of Cas3 Enzyme Cleavage (2) New tool testing an entire genome against a CRISPR molecule to predict potential errors and interactions Curator and Reporter: Aviva Lev-Ari, PhD, RN   Boom in human gene editing as 20 CRISPR trials gear up A pioneering CRISPR […]

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GENE EDITING: Promises and Challenges: HSPH and NBC News Digital, Friday, May 19, 2017  Live webcast: 12:30-1:30pm ET Reporter: Aviva Lev-Ari, PhD, RN THE ANDELOT SERIES ON CURRENT SCIENCE CONTROVERSIES GENE EDITING: Promises and Challenges  Presented jointly with NBC News Digital Friday, May 19, 2017 Live webcast: 12:30-1:30pm ET ForumHSPH.org   In labs and in clinical […]

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