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Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line Reporter: Stephen J. Williams, PhD In a Genome Research report by Marie Nattestad et al. [1], the SK-BR-3 breast cancer cell line was sequenced using a long read single molecule sequencing protocol in order to develop one […]

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Using A.I. to Detect Lung Cancer gets an A! Reporter: Irina Robu, PhD Google researchers hypothesized that computers are as good or better than doctors at detecting tiny lung cancers on CT scans, since CT scan combines data from several X-rays to produce a detailed image of a structure inside the body. CT scans produce […]

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The Sylvester Comprehensive Cancer Center of the University of Miami named 71st NCI designated Cancer Center   Reporter: Stephen J. Williams, PhD As seen in the Cancer Letter at https://cancerletter.com/articles/20190729_1/ Conversation with The Cancer Letter Sylvester becomes 71st NCI-designated cancer center Stephen Nimer Director, Sylvester Comprehensive Cancer Center   After six years of  aggressively recruiting and spending […]

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An Intelligent DNA Nanorobot to Fight Cancer by Targeting HER2 Expression Reporter and Curator: Dr. Sudipta Saha, Ph.D.   HER2 is an important prognostic biomarker for 20–30% of breast cancers, which is the most common cancer in women. Overexpression of the HER2 receptor stimulates breast cells to proliferate and differentiate uncontrollably, thereby enhancing the malignancy of […]

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Single-cell RNA-seq helps in finding intra-tumoral heterogeneity in pancreatic cancer Reporter and Curator: Dr. Sudipta Saha, Ph.D.   Pancreatic cancer is a significant cause of cancer mortality; therefore, the development of early diagnostic strategies and effective treatment is essential. Improvements in imaging technology, as well as use of biomarkers are changing the way that pancreas […]

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Engineered Bacteria used as Trojan Horse for Cancer Immunotherapy Reporter: Irina Robu, PhD Researchers are using synthetic biology— design and construction of new biological entities such as enzymes, genetic circuits, and cells or the redesign of existing biological systems—is changing medicine leading to innovative solution in molecular-based therapeutics. To address the issue of designing therapies that can induce a […]

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AI System Used to Detect Lung Cancer Reporter: Irina Robu, PhD Lung cancer is characterized by uncontrolled cell growth in tissues of the lung. The growth spreads beyond the lung by metastasis into nearby tissues. The most common symptoms are coughing (including coughing up blood), weight loss, shortness of breath, and chest pains. The two […]

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New Targeted Cancer Therapy may be ‘Possible Hope’ for Some Pancreatic Cancer Patients Reporter: Irina Robu, PhD   UPDATED on 7/18/2019 BREAKTHROUGH PANCREATIC CANCER TREATMENT PHASE III TRIAL OPENS IN ISRAEL Hope is that successful trials will allow Rafael Pharmaceuticals will receive expedited FDA approval by late 2020. BY MAAYAN JAFFE-HOFFMAN  JULY 18, 2019 18:30 “What […]

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First Cost-Effectiveness Study of Multi-Gene Panel Sequencing in Advanced Non-Small Cell Lung Cancer Shows Moderate Cost-Effectiveness, Exposes Crucial Practice Gap WASHINGTON (June 27, 2019) — The results of the first economic modeling study to estimate the cost-effectiveness of “multi-gene panel sequencing” (MGPS) as compared to standard-of-care, single-gene tests for patients with advanced non-small cell lung […]

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Tweets, Pictures and Retweets at 18th Annual Cancer Research Symposium – Machine Learning and Cancer, June 14, 2019, MIT by @pharma_BI and @AVIVA1950 for #KIsymposium PharmaceuticalIntelligence.com and Social Media   Pictures taken in Real Time   Notification from Twitter.com on June 14, 2019 and in the 24 hours following the symposium   Anirban Maitra liked your […]

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