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Cancer treatment using CRISPR-based Genome Editing System  Reporter: Irina Robu, PhD CRISPR, stands for “clusters of regularly interspaced short palindromic repeats” is one of the biggest accomplishments in science of this decade and it is the simplest tool for altering DNA sequences and modifying gene functions. The technology is adapted form the natural defense mechanism […]

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From AAAS Science News on COVID19: New CRISPR based diagnostic may shorten testing time to 5 minutes Reporter: Stephen J. Williams, Ph.D.                   A new CRISPR-based diagnostic could shorten wait times for coronavirus tests.     New test detects coronavirus in just 5 minutes By Robert F. ServiceOct. […]

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Prime Editing as a New CRISPR Tool to Enhance Precision and Versatility   Reporter: Stephen J. Williams, PhD   CRISPR has become a powerful molecular for the editing of genomes tool in research, drug discovery, and the clinic (see posts and ebook on this site below) Volume Two: Latest in Genomics Methodologies for Therapeutics: Gene […]

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CRISPR-Cas9 and the Power of Butterfly Gene Editing Reporter: Madison Davis Genome editing is a relatively new branch of genetic engineering that utilizes modern technologies in altering, inserting, or deleting selective DNA sequences within cells.  CRISPR-Cas9, otherwise known as “Clustered Regularly Interspaced Short Palindromic Repeat”, is a groundbreaking genome editing technique for scientists, as it […]

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CRISPR companies calling for article retraction from Nature Methods – If the same or similar sequence of letters appears elsewhere in the genome, that can result in an unintentional or off-target edit – Concerns of Harm caused by Gene Editing using CRISPR-Cas9   Reporter: Aviva Lev-Ari, PhD, RN Storm around the call for “Nature Methods […]

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Update 6/11/2020 CRISPR-IL used to develop next-gen genome editing products Haifa-based Pluristem Therapeutics is a regenerative medicine company that plans to develop next-generation multi-species genome editing products for human, plant and animal DNA that could improve work done in the pharma, agriculture and aquaculture industries. The CRISPR-IL consortium includes Sheba Medical Center and Schneider Children’s Medical […]

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Merck KGaA-owned Sigma-Aldrich has petitioned the US Patent and Trademark Office (USPTO) to open an interference proceeding between its own pending CRISPR-Cas9 patents and patents awarded to the University of California, Berkeley (UC Berkeley). On Friday, July 19, Sigma-Aldrich submitted the request, available on blog PatentDocs, asking for a parallel interference to the one declared by the […]

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At Technical University of Munich (TUM) Successful Genetical modification of a patient’s own immune cells, T cell receptors, using CRISPR-Cas9 gene editing tool. The engineered T cells are very similar to the physiological immune cells. Reporter: Aviva Lev-Ari, PhD, RN   Targeted exchange using the CRISPR-Cas9 gene scissors The problem with conventional methods is that the […]

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FIVE Forthcoming Books on CRISPR in 2019-2020: Flooded market or CRISPR-fatigued readers – Not to Worry !!!!! Author: Aviva Lev-Ari, PhD, RN   From: Aviva Lev-Ari <AvivaLev-Ari@alum.berkeley.edu> Date: Thursday, July 4, 2019 at 8:39 PM To: <damian.garde@statnews.com> Cc: Marcus W Feldman <mfeldman@stanford.edu>, “Stephen Williams, PhD” <sjwilliamspa@comcast.net>, Aviva Lev-Ari <AvivaLev-Ari@alum.berkeley.edu>, Gail Thornton <gailsthornton@yahoo.com> Subject: Regarding your […]

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Optimization of CRISPR Gene Editing with Gold Nanoparticles Reporter: Irina Robu, PhD The CRISPR-Cas9 gene editing system has been welcomed as a hopeful solution to a range of genetic diseases, but the expertise has proven hard to deliver into cells. One plan is to open the cell membrane using an electric shock, but that can […]

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