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Ethics Behind Genetic Testing in Breast Cancer: A Webinar by Laura Carfang of survivingbreastcancer.org

Posted in Bio-Ethics, Ethics and Leadership, Genetics & Pharmaceutical, Health Economics and Outcomes Research, Healthcare costs and reimbursement, Healthcare Reform, Patient Experience, Patient Outlook, Patient-centered Medicine, Uncategorized, Women Health, tagged , , , , , , , on March 12, 2020| Leave a Comment »


Ethics Behind Genetic Testing in Breast Cancer: A Webinar by Laura Carfang of survivingbreastcancer.org Reporter: Stephen J. Williams, PhD The following are Notes from a Webinar sponsored by survivingbreastcancer.org  on March 12,2020. The webinar started with a brief introduction of attendees , most who are breast cancer survivors.  Survivingbreastcancer.org is an organization committed to supplying […]

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Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Posted in Cancer - General, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Genomics, Genomic Testing: Methodology for Diagnosis, Next Generation Sequencing (NGS), Single Cell Genomics, tagged , , , , , , , , , , , , on August 14, 2019| Leave a Comment »


Complex rearrangements and oncogene amplification revealed by long-read DNA and RNA sequencing of a breast cancer cell line Reporter: Stephen J. Williams, PhD In a Genome Research report by Marie Nattestad et al. [1], the SK-BR-3 breast cancer cell line was sequenced using a long read single molecule sequencing protocol in order to develop one […]

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Relations between Breast Cancer and DIET: amino acid called asparagine

Posted in Breast Cancer - impalpable breast lesions on February 8, 2018| Leave a Comment »


Relations between Breast Cancer and DIET: amino acid called asparagine Reporter: Aviva Lev-Ari, PhD, RN     Diet may influence the spread of a deadly type of breast cancer, study finds February 7, 2018, Cedars-Sinai Medical Center Three-dimensional cell culture of breast cancer cells. Credit: National Institutes of Health (Dao Tiensinh) A single protein building […]

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Reduction in Mortality in Breast Cancer Patients: Outcome of Drug Interactions

Posted in Cancer and Current Therapeutics, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Genomics, Cancer Informatics, Genomic Expression on December 14, 2016| Leave a Comment »


Reduction in Mortality in Breast Cancer Patients: Outcome of Drug Interactions  Reporter: Aviva Lev-Ari, PhD, RN Drug interactions using gene-expression data: common molecular pathways that might account for drug pairs with apparent synergistic effects, searching for drug-protein interactions in the twoXAR company’s database. “This is a holistic look at the data — EHR, gene expression, […]

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Breast Cancer Screening Imaging Technology: 2D Mammography vs Combination of 3D and 2D Mammography vs Combination of 3D and Synthetic 2D – Smaller, invasive cancers detection achieved

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Medical Imaging Technology, Image Processing/Computing, MRI, CT, Nuclear Medicine, Ultra Sound, tagged on July 19, 2016| Leave a Comment »


Breast Cancer Screening Imaging Technology:  2D Mammography vs Combination of 3D and 2D Mammography vs Combination of 3D and Synthetic 2D – Smaller, invasive cancers detection achieved   Reporter: Aviva Lev-Ari, PhD, RN   Mean tumor size for the 46 invasive cancers detected with both 2D mammography alone and a combination of 2D and 3D mammography was […]

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No Significant Long-term Risk of Breast Cancer caused by Ovarian Stimulation for In Vitro Fertilization

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Reproductive Biology & Bio Instrumentation, tagged , on July 19, 2016| Leave a Comment »


No Significant Long-term Risk of Breast Cancer caused by Ovarian Stimulation for In Vitro Fertilization  Reporter: Aviva Lev-Ari, PhD, RN   Original Investigation | July 19, 2016 Ovarian Stimulation for In Vitro Fertilization and Long-term Risk of Breast Cancer Alexandra W. van den Belt-Dusebout, PhD1; Mandy Spaan, MSc1; Cornelis B. Lambalk, MD, PhD2; Marian Kortman, MD3; Joop S. E. Laven, MD, PhD4; Evert J. P. van Santbrink, MD, PhD5; […]

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Breast Cancer Disparities to be Sponsored by NIH: NIH Launches Largest-ever Study of Breast Cancer Genetics in Black Women

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Screening, Genome Biology, Genomic Expression, Genomic Testing: Methodology for Diagnosis, tagged on July 6, 2016| Leave a Comment »


Breast Cancer Disparities to be Sponsored by NIH: NIH Launches Largest-ever Study of Breast Cancer Genetics in Black Women Reporter: Aviva Lev-Ari, PhD, RN   The largest study ever to investigate how genetic and biological factors contribute to breast cancer risk among black women launched today. This collaborative research project will identify genetic factors that […]

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Targeted Therapy for Triple Negative Breast Cancer

Posted in Anaerobic Glycolysis, Biochemical pathways, CANCER BIOLOGY & Innovations in Cancer Therapy, Cancer Informatics, Cell Biology, Signaling & Cell Circuits, Chemical Biology and its relations to Metabolic Disease, Chemical Genetics, Clinical & Translational, Clinical Diagnostics, Gene Regulation, Genetics & Innovations in Treatment, Genetics & Pharmaceutical, Genome Biology, Genomic Expression, Metabolism, Personalized and Precision Medicine & Genomic Research, Pharmaceutical Drug Discovery, tagged , , , on May 19, 2016| Leave a Comment »


Targeted Therapy for Triple Negative Breast Cancer Curator: Larry H. Bernstein, MD, FCAP LPBI   Triple-Negative Breast Cancer Target Is Found May 17, 2016   Researchers at UC Berkeley discover a target that drives cancer metabolism in triple-negative breast cancer. http://www.technologynetworks.com/Genotyping/news.aspx?ID=191502 UC Berkeley researchers have found a long-elusive Achilles’ heel within “triple-negative” breast tumors, a common […]

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Chemotherapy Benefit in Early Breast Cancer Patients

Posted in Anticancer Resistance, Bio Instrumentation in Experimental Life Sciences Research, Biological Networks, BioTechnology - Venture Creation, Cancer and Current Therapeutics, Cell Biology, Signaling & Cell Circuits, Chemical Genetics, Clinical & Translational, Clinical Genomics, Computational Biology/Systems and Bioinformatics, Curation, Disease Biology, Drug Delivery Platform Technology, Experimental validation, Gene Regulation, Genetics & Innovations in Treatment, Genetics & Pharmaceutical, Genomic Expression, Innovations, Intellectual Property, Innovations, Commercialization, Investment in technological breakthrough, Medical and Population Genetics, Metabolism, Metabolomics, Molecular Genetics & Pharmaceutical, Pharmaceutical Analytics, Pharmaceutical Drug Discovery, Pharmacologic toxicities, Population Health Management, Population Health Management, Genetics & Pharmaceutical, Signaling, Signaling & Cell Circuits, Small Molecules in Development of Therapeutic Drugs, Technology Advance Assessment of, tagged , , , , , , , , , , on April 20, 2016| Leave a Comment »


Chemotherapy Benefit in Early Breast Cancer Patients Larry H Bernstein, MD, FCAP, Curator LPBI   Agendia’s MammaPrint® First and Only Genomic Assay to Receive Level 1A Clinical Utility Evidence for Chemotherapy Benefit in Early Breast Cancer Patients http://www.b3cnewswire.com/201604191373/agendias-mammaprintr-first-and-only-genomic-assay-to-receive-level-1a-clinical-utility-evidence-for-chemotherapy-benefit-in-early-breast-cancer-patients. Clinical high-risk patients with a low-risk MammaPrint® result, including 48 percent node-positive, had five-year distant metastasis-free survival […]

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Lipids link to breast cancer

Posted in Cancer - General, CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Clinical Genomics, Curation, Cytoskeleton, Disease Biology, Genome Biology, Lipid metabolism, Lipids, tagged , , , , , , , , , , , , , , on April 10, 2016| Leave a Comment »


Lipids link to breast cancer Larry H. Bernstein, MD, FCAP, Curator LPBI   Lipids Found Critical to Breast Cancer Cell Proliferation http://www.genengnews.com/gen-news-highlights/lipids-found-critical-to-breast-cancer-cell-proliferation/81252572/ http://www.genengnews.com/Media/images/GENHighlight/112523_webApr6_2016_IRBBarcelona_BreastTumorsLIPD3119618425.jpg   Scientists in Spain report finding that breast cancer cells need to take up lipids from the extracellular environment so that they can continue to proliferate. The main protein involved in this […]

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