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Search Results for 'Aspirin'

The Promise of Low-Dose Aspirin on Longevity in the Geriatric Population: No Effect on Outcomes in the US and Australia

Posted in Atherogenic Processes & Pathology, Cardiovascular Research, Coagulation Therapy and Internal Bleeding, Frontiers in Cardiology and Cardiovascular Disorders, HTN, inflammation independent of lipid levels, Pharmacotherapy of Cardiovascular Disease, Stroke on September 24, 2018| Leave a Comment »


The Promise of Low-Dose Aspirin on Longevity in the Geriatric Population: No Effect on Outcomes in the US and Australia Reporter: Aviva Lev-Ari, PhD, RN UPDATED on 10/17/2018 https://www.nejm.org/doi/full/10.1056/NEJMoa1800722 Effect of Aspirin on Disability-free Survival in the Elderly ORIGINAL ARTICLE Effect of Aspirin on Disability-free Survival in the Healthy Elderly J.J. McNeil and Others      […]

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Aspirin Advocate vs Skeptic: Any Common Ground? – Medscape

Posted in Uncategorized on November 3, 2014| Leave a Comment »


UPDATED on 7/17/2016 Aspirin Fails to Prevent Cardiovascular Events in High-Risk Patients Significant bleeding risk may outweigh any benefit Aspirin Fails to Prevent Cardiovascular Events in High-Risk Patients   Aspirin Advocate vs Skeptic: Any Common Ground? Source: login.medscape.com See on Scoop.it – Cardiovascular Disease: PHARMACO-THERAPY

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Intracranial Vascular Stenosis: Comparison of Clinical Trials: Percutaneous Transluminal Angioplasty and Stenting (PTAS) vs. Clot-inhibiting Drugs: Aspirin and Clopidogrel (dual antiplatelet therapy) – more Strokes if Stenting

Posted in Atherogenic Processes & Pathology, Cardiac and Cardiovascular Surgical Procedures, Cerebrovascular and Neurodegenerative Diseases, Innovations in Neurophysiology & Neuropsychology, PCI on October 15, 2014| 2 Comments »


Intracranial Vascular Stenosis: Comparison of Clinical Trials: Percutaneous Transluminal Angioplasty and Stenting (PTAS) vs. Clot-inhibiting Drugs: Aspirin and Clopidogrel (dual antiplatelet therapy) – more Strokes if Stenting   Reporter: Aviva Lev-Ari, PhD, RN   UPDATED on 8/5/2018 Clopidogrel plus aspirin bests aspirin alone for CV event reduction: Cochrane Source: JAMA, Published online July 26, 2018. doi:10.1001/jama.2018.9641 Curated […]

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Platelet Endothelial Aggregation Receptor-1 (PEAR1) Gene to be most strongly associated with Dual Antiplatelet Therapy Response: Genetic Determinants of Variable Response to Aspirin (alone and in combination with Clopidogrel)

Posted in Atherogenic Processes & Pathology, Cardiac and Cardiovascular Surgical Procedures, Cardiovascular Pharmacogenomics, Cardiovascular Research, Cell Biology, Signaling & Cell Circuits, Chemical Genetics, Coagulation Therapy and Internal Bleeding, Computational Biology/Systems and Bioinformatics, FDA Regulatory Affairs, Frontiers in Cardiology and Cardiovascular Disorders, Genome Biology, Genomic Testing: Methodology for Diagnosis, HTN, Medical and Population Genetics, Origins of Cardiovascular Disease, PCI, Personalized and Precision Medicine & Genomic Research, Pharmacotherapy of Cardiovascular Disease, Stents & Tools, Valves & Tools, tagged , , , , , , on December 30, 2013| Leave a Comment »


Platelet Endothelial Aggregation Receptor-1 (PEAR1) Gene to be most strongly associated with Dual Antiplatelet Therapy Response: Genetic Determinants of Variable Response to Aspirin (alone and in combination with Clopidogrel) Reporter: Aviva Lev-Ari, PhD, RN 4 Genetic Variation in PEAR1 is Associated with Platelet Aggregation and Cardiovascular Outcomes Joshua P. Lewis1, Kathleen Ryan1, Jeffrey R. O’Connell1, Richard B. Horenstein1,Coleen M. Damcott1, Quince […]

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PIK3CA mutation in Colorectal Cancer may serve as a Predictive Molecular Biomarker for adjuvant Aspirin therapy

Posted in Biological Networks, Gene Regulation and Evolution, Biomarkers & Medical Diagnostics, CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Signaling & Cell Circuits, Chemical Biology and its relations to Metabolic Disease, Chemical Genetics, Genome Biology, Genomic Testing: Methodology for Diagnosis, Liver & Digestive Diseases Research, Medical and Population Genetics, Metabolomics, Molecular Genetics & Pharmaceutical, Personalized and Precision Medicine & Genomic Research, Population Health Management, Genetics & Pharmaceutical, tagged , , , , , , on November 28, 2012| 8 Comments »


Reporter: Aviva Lev-Ari, PhD, RN Aspirin Use, Tumor PIK3CA Mutation, and Colorectal-Cancer Survival N Engl J Med 2012; 367:1596-1606 October 25, 2012DOI: 10.1056/NEJMoa1207756 BACKGROUND Regular use of aspirin after a diagnosis of colon cancer has been associated with a superior clinical outcome. Experimental evidence suggests that inhibition of prostaglandin-endoperoxide synthase 2 (PTGS2) (also known as cyclooxygenase-2) by aspirin […]

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Aspirin a Day Tied to Lower Cancer Mortality

Posted in CANCER BIOLOGY & Innovations in Cancer Therapy, Cell Biology, Signaling & Cell Circuits, Chemical Biology and its relations to Metabolic Disease, tagged , , , , , , on August 11, 2012| 4 Comments »


Aspirin a Day Tied to Lower Cancer Mortality Reporter: Aviva Lev-Ari, PhD, RN Aspirin a Day Tied to Lower Cancer Mortality Download Complimentary Source PDF  By Nancy Walsh, Staff Writer, MedPage Today Published: August 10, 2012 Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania  http://www.medpagetoday.com/HematologyOncology/OtherCancers/34149?utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=WC&eun=g99985d0r&userid=99985&email=avivalev-ari@alum.berkeley.edu&mu_id=5099207 Action Points This study […]

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Aortic Stenosis (AS): Managed Surgically by Transcatheter Aortic Valve Replacement (TAVR) – Search Results for “TAVR” on NIH.GOV website, Top 16 pages

Posted in Aortic Valve: TAVR, TAVI vs Open Heart Surgery, Atherogenic Processes & Pathology, Cardiac and Cardiovascular Surgical Procedures, Congenital Heart DIsease, Frontiers in Cardiology and Cardiovascular Disorders, Medical Devices R&D and Inventions, Origins of Cardiovascular Disease, TAVI vs Open Heart Surgery, Valves & Tools on August 14, 2018| Leave a Comment »


Aortic Stenosis (AS): Managed Surgically by Transcatheter Aortic Valve Replacement (TAVR) – Search Results for “TAVR” on NIH.GOV website, Top 16 pages Reporter: Aviva Lev-Ari, PhD, RN   UPDATED on 9/24/2018 Sapien 3, CoreValve Evolut R on Par for Aortic Stenosis Head-to-head trial also shows local, general anesthesia outcomes similar by Ashley Lyles, Staff Writer, MedPage Today September 23, […]

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Single-Author Reporting on MedTech and Cardiac Medical Devices by Aviva Lev-Ari, PhD, RN

Posted in on August 6, 2018|


Single-Author Reporting on MedTech and Cardiac Medical Devices by Aviva Lev-Ari, PhD, RN On 8/13/2018 Reportings, N = 150   157r  Comparison of four methods in diagnosing acute myocarditis: The diagnostic performance of native T1, T2, ECV to LLC Reporter: Aviva Lev-Ari, PhD, RN https://pharmaceuticalintelligence.com/2018/08/08/comparison-of-four-methods-in-diagnosing-acute-myocarditis-the-diagnostic-performance-of-native-t1-t2-ecv-to-llc/   156r   Left ventricular outflow tract (LVOT) obstruction (LVOTO): The Role […]

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Coronary Artery Interventions: Balloon, Stent, Drug-eluting Stent and Antiplatelet Demand

Posted in Academic Publishing, CABG, Cardiac and Cardiovascular Surgical Procedures, Cardiovascular Pharmacogenomics, PCI, tagged , , , , , on August 5, 2018| Leave a Comment »


Coronary Artery Interventions: Balloon, Stent, Drug-eluting Stent and Antiplatelet Demand Curator: Justin D. Pearlman, MD, PhD, FACC Italicized text represents the voice of Dr. Pearlman Coronary Artery Disease (CAD), causing impeded blood supply to the heart, constitutes a major cause of disability and death, amounting to triple all forms of cancer combined. The warning symptoms […]

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Two Classes of Antithrombotic Drugs: Anticoagulants and Antiplatelet drugs

Posted in Acute coronary syndrome, Acute Myocardial Infarction, Atherogenic Processes & Pathology, Cardiovascular Research, Coagulation Therapy and Internal Bleeding, congestive heart failure, endovascular thrombectomy, Frontiers in Cardiology and Cardiovascular Disorders, Hematology, Origins of Cardiovascular Disease, Pharmacotherapy of Cardiovascular Disease, Stents & Tools, Stroke, Valves & Tools, Vascular Diseases on June 25, 2018| Leave a Comment »


Two Classes of Antithrombotic Drugs: Anticoagulants and Antiplatelet drugs Reporter: Aviva Lev-Ari, PhD, RN These drugs are used to treat strokes, myocardial infarctions, pulmonary embolisms, disseminated intravascular coagulation (DIC) and deep vein thrombosis (DVT) — all potentially life-threatening conditions. THERAPEUTIC STRATEGIES • Degrade fibrinogen/fibrin (fibrinolytic agents) GOAL: eliminate formed clots • Inhibit clotting mechanism (anticoagulants) […]

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