Double Downside of HIV CRISPR therapy Larry H. Bernstein, MD, FCAP, Curator   Hitting HIV with CRISPR/Cas9 Can Arouse Resistance http://www.genengnews.com/gen-news-highlights/ This visual abstract depicts how HIV-1 can escape Cas9/sgRNA-mediated inhibition. The researchers reveal that the NHEJ repair machinery generates mutations in the HIV-1 Cas9 cleavage site that result in two outcomes: viral replication suppression … Continue reading Double downside of HIV CRISPR therapy