Neutrophil Serine Proteases in Disease and Therapeutic Considerations Larry H. Bernstein, MD, FCAP, Curator LPBI   SERPINB1 Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Belongs to the serpin family. Ov-serpin subfamily. Note: This description may include information from UniProtKB. Chromosomal Location of Human Ortholog: 6p25 Cellular Component: extracellular space; membrane; … Continue reading Neutrophil Serine Proteases in Disease and Therapeutic Considerations