Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Francis S. Collins, M.D., Ph.D. – UNDERWENT SURGERY LAST WEEK on his behalf the Award for presented to his designee, Kathy Hudson, PhD, Depute Outreach, NIH
Director, National Institutes of Health (NIH)

PERSONAL ADDRESS VIA VIDEO

William S. Dalton, Ph.D., M.D.
CEO, M2Gen
Director, DeBartolo Family Personalized Medicine Institute at Moffitt Cancer Center

Deborah Dunsire, M.D.
President and CEO, FORUM Pharmaceuticals

• Frontaltemporal Dementia
• Progranulin levels in FTD-GRN – FRM0334 Increased PRGN Expression
• Reverse GRN mRNA deficit

S. Roopom Banerjee
President and CEO, RainDance Technologies

• Single molecule
• Single cell sequencing
• Power of Biological Information: mission Genomics and Big Data for detection discoveries for long term
• ACCESS is still difficult: Mutations very many to be looked in a Big Data context and technologies
• Early detection and Accurate Monitoring Remain Elusive
• Colorectal Cancer: Liquid Biopsy (Plasma)
• Remission COlon A vs Relapse Colon B
• mCRC patients with mutated sub-clones <1 benefit anti ECFR therapies
• proporsion of KRAS mutated
• patient interaction
• Genetics linkage to markers – is Hypothesis driven
• illumina – repertoire of disease and immune system is a specific area that Illumina’s solution is too generic to solve
• Shareholder value
• Referendum of Sloane Kettering and MD Anderson in dealing with FDA on oncology testing

L. Patrick James, M.D.
Chief Clinical Officer, Health Plans and Policy, Quest Diagnostics

• Pathologist
• Persolalized Experience: Interactive Insights
• Provider

1. Result reports within Insights
2. Interactive Reporting: Physician View and Patient View
3. Tailor Report Formts

• Quest Diagnostics: MDs struggle with Diagnostics: Personalized Information for MDs and PAtients
• Dementia Pathway: Data Integration and Decision Support and Concierge Services
• Population Health Management
• Provision and Integrator company
• Algorithms at the Quest Diagnosis Office serves 200,000 MDs in the Communities
• Underwriters  make decisions on coverage – high risk patients coverage
• Partnership with novolog: data diagnostics in Clinical Medicine
• Monitising data by Sharing with insurers for them to set policies
• proficiency testing
• Testing can be meaningless rather thn meaningful

Jonathan Sheldon, Ph.D.
Global Vice President Healthcare, Oracle

• Sw and HW integration
• Life Sciences Sector – 5 years ago investment from HealthCare to Life Sciences
• Extremely large Data sets, quality of data is critical
•  Scale Population Health with Precision Medicine
• Mayo  Clinics collaboration
• mapping data is hard

Plan:

• start with integration of EMR Clinical Data plus Genomics by using data architecture