Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Richard Hamermesh, D.B.A.
Senior Fellow and Former MBA Class of 1961 Professor of Management Practice
Harvard Business School

with
Robert Kraft
Chairman and Chief Executive Officer
Kraft Group

will introduce Harvard Business School’s “Precision Trials Challenge” – Kraft Family Foundation donate $20Million for Precision Medicine harnessed to understand disease 

HBS and the Broad Institute – collaboration Catalyst – computational bottlenecks

• precision Medicine Ecosystem
• incubation of ideas
• commercialize collaborative initiative
• Initiate a Challenge in January 2016 – Faster, smaller, cheaper and more efficient Clinical Trial by using Precision Medicine and bringing FASTER to market new drugs.
• Prize of $2000 for NEW ideas on improving Clinical Trials

Elizabeth Karlson, M.D.
Co-Investigator, Partners Biobank, Partners HealthCare Personalized Medicine; Associate Professor of Medicine, Harvard Medical School

• Biobanks links to clinical data and EMR
• Pharmco-genetics focus on Cancer
• Beside Cancer, what other diseases BioBank could help?
• Q – biggest challenge to implement Precision Medicine in your Country
• Patients consent to be in BioBank and they do not get the results back
• Reactions of MDs and Patients: False positive requires more tests
• How can we handle getting back wiht results to 1Million Volunteers
• lessons from BioBank that can inform the President Cohort PMI

PARTNERS Experience

• Risk prediction model
• calling back patients with results
• bIoBank is linked for query Portal integrates all data for all participants
• Genotyping 25,000 Patients
• Honing Phenotypes and curated Phenotypes connected with gentic sequence data more evidence needed to call Data Acitonable
• Cost impact LDL receptor, genetic component in the context of Trial
• consent to PMI, may be some Patients will
• Sharing Consent FORMS – a possibility for Standardization, All online
• Partners HealthCare was approved by IRB in 18 month and the FORM will stand for ever.
• Patient Portal: Patient identity Verified
• Patient Portal used only by Educate White Populations
• A Team to do Face to Face
• Online recruitment targeted to White Educated

Hadi Abderrahim, M.D., Ph.D., M.B.A.
Managing Director, Qatar Biobank

• Hospital system develop the use of Biobanking, model for data collection using questionnaire Measurement of relations of the Database, volunteer patients, 1000 participant to 5000 participants
• Biobank can be instrumental for Diabetes
• education occur at the Clinic level not online

Taro Inada, Ph.D.
General Manager, Denka Co., Ltd. Japan

• Chemical Company
• Colon Cancer in Japan is increasing
• Precision Medicine: Protocol for Diagnosis
•  infectious disease in Japan
•  Sharing information keeping the motivation and the relationship with Academia

Nahid Turan, Ph.D.

PI, National Institute of General Medical Science Human Genetic Cell Repository, Coriell Institute

• gene discovery to prolong life
• mutation on a gene protected from EBOLA
• Drug Safety of upmost importance
• follow up all patients that has samples in the BioBank
• challenge is big with Data Collection and reporting back to patients
• Privacy
• Risk for melanoma – Education needed for Patients

QUESTIONS FROM THE AUDIENCE

• Q – Channels for Patient Education
• A – Online is very participatory