LIVE 11/3/2015 1:30PM @The 15th Annual EmTech MIT – MIT Media Lab: Top 10 Breakthrough Technologies & 2015 Innovators Under 35
Reporter: Aviva Lev-Ari, PhD, RN
Live Press Coverage in REAL TIME Aviva Lev-Ari, PhD, RN Director & Founder, Leaders in Pharmaceutical Business Intelligence, Boston Co-Founder, GDE |
1:30 Lunchtime Programming:Robots Among Us.
Discover how the country more famous for the “Three Fs”—food, fashion, and fast cars—is among the heaviest and earliest adopters of robotics and automation in its advanced-manufacturing-driven economy.
Arturo Baroncelli
Business Development Manager, Comau Robotics, Engelberger Prize 2005
Presented by the Italian Trade Agency
Manufacture of robots from 3kg & 0.6 Meters to 800 kg: COMAU – World largest system integrator, manufacturer
- robots used in auto manufacturing
- 2018 2.3 Million of robots on floors
- Italy is the largest robot consumers the density of robots on floors
- Italy and Japan are the Worls leaders since 1973 on
- 50 years of highest productivity, quality and reliability, cost effectiveness
- 90s the Service robot
- in industrial automation
- Technical complexity (6 axes no sensors to 30-50 axes tactile & vision system) and complexity of external environment (non structural env high interaction with humans to structured intermediate by cooperative Robots = 6-14 axes single-double arms without vision, small payload % short reach
- cooperative robot: Piece, Soft Gripper, robot
- dangerous grippers, hazardous Pieces
Ms. Kennedy:
- China has the most robots
- 3D Printing
China 56,000 robots will grow 15% a year
Arturo: enabling technologies
- Service robotics
- innovations in robotics – new applications
- Vision is no longer an innovations
- Learning, teaching the robots
2:00 Breaking the Code for Better Health
A timely examination of breakthroughs in genomic engineering to fight human diseases.
Katrine Bosley
Chief Executive, Editas Medicine
Transformative Genome Editing
Repair broken genes, Cystics fibrosis, Huntington, 6,000 genetic diseases, 25 years ago sequences,
CRISPR: ability to sequence rapidly and cheaply
- guide RNA – complex nuclease protein (Cas9)
- leverages native pairing mechanism od RNA and DNA to precisely
- diffrent Mutations require diferent Edits
- Cur & Revise, cut and remoce, cut anf repair
- Multiple Options for Delivery of CRISPR Mediicnes
- EDITAS – 4 parts
- 1.achieve the right repaire
- 2. specificically
- Expanding technology to helpmore patients
- Leber Concenital Amaurosis (LCA10) a genetic form of progressive blindness – retinal degeneration, no tritment in US or Europe – visual accuity measures
- CEP290 Gene Editing to Treat LCA10
- Exon 25,26, glitch exon 27, 28
- get rid of glitch remove the piecce of DNA
- functional Full Length Protein
- mRNA Expression vs Increase Full-Length Protein Expression
- Potential to repair any broken gene
- recombinant protein
Jason: visus mechanism as inspiration
- Augmentation vs PREVENTIVE MEDICINE
Ethical edit human germ line – is not scientific but societal, regulatory FDA advisory Committee at NIH — debate to have
Editas, CEO
- Gentic heritage – alterations in,
- On the question of Moratorium on Human Germ Line – Editas is dealing wiht adult cells
- Clinical Trials, When?? What do you work on parallel or in sequence
- 2009 raising money was hard in 2015 – parallel technology of CRISPR – understand mutation and disease
- investing in parallel is reasonable
- Clinical Trials in 2017
- Team and Capital — IP Contraversy: intensity,
- Cas9 – Other Enzymes?? Other enzymes — features are different in 5 years we will know more
- Specificity, cut and repair is getting to Medicine
- Alternative methods will be better to be used with other methods
- Diseases to target Vision, Liver,
- Sickle Cells: Stem cells to be use in Gene Therapy vs Gene Editing – correct gene in place vs systemic
Complement your views with her Perspective by reading
CRISPR Gene Editing to Be Tested on People by 2017, Says Editas
A biotechnology company says it will test advanced gene-engineering methods to treat blindness.
2:30 Meet the Innovators Under 35
Polina Anikeeva
Assistant Professor, MIT Department of Materials Science and Engineering
2015 Innovator Under 35
Canan Dagdeviren
Postdoctoral Researcher, The David H. Koch Institute for Integrative Cancer Research at MIT
2015 Innovator Under 35
- Pace makers – heart – mechanical energy
- Gastric Pacemaker
Gozde Durmus
Postdoctoral Research Fellow, Stanford University
2015 Innovator Under 35
- Antibiotic resistance = Superbags
- alternative to culturing cells to identify resistence or sensitivity
Gilad Evrony
Physician-Scientist, Mount Sinai Hospital
2015 Innovator Under 35
- Somatic mutations – how many are
- single-neuron sequencing – neurological and psychiatry diseases
- genetics – Autism is one area of the brain
Rikky Muller
CTO and Cofounder, Cortera Neurotechnologies
2015 Innovator Under 35
- robotics arm to assist impairment
- Epilapsy
- one chip implanted and interact with entire body – remotely monitored
- targeted stimulation to the Brain small devices
ANALOG DEVICES Presentations – 50 years old – Culture of Engineering embrass technology
- Autonomous Mapping – drones
- IoT – a new machine to integrate – development cost $100Million
- John Deere machine for Smart Agriculture
- Sensor: Anti collition devices
- MEMS Gyroscope in the cloud – Signal Chain
- Analog filters
- Swarm Control – tractors in the agriculture field
- Sensors must be encreepted
Enablers: LIDAR Sensors, Lower Power Crypto, Robust SW, high bandwidth Sensors
Safety & Security: Secure trusted sensors, better signals, better data, self-healing SW
high performance matters: multiple sensors
Please see the following Meeting @TechReview @Jason_Pontin and #EmTechMIT on Twitter and follow us at @pharma_BI
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General meeting #
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Please see the Following Talk Specific @ and #
Talk Time @ #
Arturo Baroncelli | Nov3 12:30PM | @comaugroup | #ItalianTradeAgency #ICEAgenzia #FEDERMACCHINE #COMAU
#tech #innovation #investing #startup #trade |
Breaking the Code for Better Health: Katrine Bosley | Nov3 2:00PM | @editasmed
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#CRISPR
#biotech
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Meet the Innovators Under 35 | Nov3 2:30 PM | @MIT | #EmTechMIT
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