8:00AM 11/13/2014 – 10th Annual Personalized Medicine Conference at the Harvard Medical School, Boston
REAL TIME Coverage of this Conference by Dr. Aviva Lev-Ari, PhD, RN – Director and Founder of LEADERS in PHARMACEUTICAL BUSINESS INTELLIGENCE, Boston http://pharmaceuticalintelligence.com
8:00 A.M. Welcome from Gary Gottlieb, M.D.
Opening Remarks:
Partners HealthCare is the largest healthcare organization in Massachusetts and whose founding members are Brigham and Women’s Hospital and Massachusetts General Hospital. Dr. Gottlieb has long been a supporter of personalized medicine and he will provide his vision on the role of genetics and genomics in healthcare across the many hospitals that are part of Partners HealthCare.
Scott Weiss, M.D., M.S. @PartnersNews
Scientific Director, Partners HealthCare Personalized Medicine;
Associate Director, Channing Laboratory/
Professor of Medicine, Harvard Medical School @harvardmed
Welcome
Engine of innovations
- lower cost – Accountable care
- robust IT infrastructure on the Unified Medical Records
- Lab Molecular Medicine and Biobanks
- 1. Lab Molecular medicine
- 2. Biobank
- 3. Translations Genomics: RNA Sequencing
- 4. Medical Records integration of coded diagnosis linked to Genomics
BIOBANKS – Samples and contact patients, return actionable procedures
LIFE STYLE SURVEY – supplements the medical record
GENOTYPING and SEQUENCING – less $50 per sequence available to researcher / investigators
RECRUITMENT – subject to biobank, own Consents – e-mail patient – consent online consenting — collects 16,000 patients per month – very successful Online Consent
LAB Molecular Medicine – CLIA — genomics test and clinical care – EGFR identified as a bio-marker to cancer in 3 month a test was available. Best curated medical exon databases Emory Genetics Lab (EMVClass) and CHOP (BioCreative and MitoMAP and MitoMASTER). Labs are renowned in pharmacogenomics and interpretability.
IT – GeneInsight – IT goal Clinicians empowered by a workflow geneticist assign cases, data entered into knowledge base, case history, GENEINSIGHT Lab — geneticists enter info in a codified way will trigger a report for the Geneticist – adding specific knowledge standardized report enters Medical Record. Available in many Clinics of Partners members.
Example: Management of Patient genetic profiles – Relationships built between the lab and the Clinician
Variety of Tools are in development
GenInsight Team –>> Pathology –>> Sunquest Relationship
- Mass General (MGH) & Brigham Women’s (BWH) — Chart in EM will have the Genetic Profile of a Patients checking in
The Future
Genetic testing –>> other info (Pathology, Exams, Life Style Survey, Meds, Imaging) — Integrated Medical Record
Clinic of the Future-– >> Diagnostics – Genomics data and Variants integrated at the Clinician desk
Gary Gottlieb, M.D. @PartnersNews
President and CEO, Partners HealthCare
2001 – Center for Genomics was started at Partners, 2008 Genomics and Other Omis, Population Health, PM – Innovations at Partners.
Please Click on Link Video on 20 years of PartnersHealthcare
Video of Dr. Gottlieb at ECRI conference 2012
Why is personalized medicine important to Partners?
From Healthcare system to the Specific Human Conditions
- Lab translate results to therapy
- Biobank +50,000 specimens links to Medical Records of patients – relevant to Clinician, Genomics to Clinical Applications
Questions from the Podium
- test results are not yet available online for patients
- clinicians and liability – delays from Lab to decide a variant needs to be reclassified – alert is triggered. Lab needs time to accumulated knowledge before reporting a change in state.
- Training Clinicians in above type of IT infrastructure: Labs around the Nations deal with VARIANT RECLASSIFICATION- physician education is a must, Clinicians have access to REFERENCE links.
- All clinicians accessing this IT infrastructure — are trained. Most are not yet trained
- Coordination within Countries and Across Nations — Platforms are Group specific – PARTNERS vs the US IT Infrastructure — Genomics access to EMR — from 20% to 70% Nationwide during the Years of the Obama Adm.
- Shakeout in SW linking Genetic Labs to reach Gold Standard
Click to see Advanced Medical Education Partners Offers
– See more at: http://personalizedmedicine.partners.org/Education/Personalized-Medicine-Conference/Program.aspx#sthash.qGbGZXXf.dpuf
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